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s**o
发帖数: 578 | 2 Bone scan will tell.
Xeloda is used for breast cancer. Its expensive though. My dad uses for
gastric canter, bone metastatis. $2300 for 14 days of usage. 14 days on and
7 days off. |
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t****o
发帖数: 41 | 4 nod，有第一个，她换过药，今天晚上问问6年来换过的药。 |
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s****n
发帖数: 147 | 7 Most possibility is that it has spread to bone.
If that
1.Hormonal Therapy. Cut ovary or injecting every month.
2. If very painful, using Sr89 or Sm 153
Bless |
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l*****O
发帖数: 402 | 8 HER2 ++++ 应该有转移高风险。你可以试Herceptin if bone metastasis is
confirmed. |
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l*****O
发帖数: 402 | 9 if she used tamoxifen before, then she could use aromatase inhibitors now
given she is postmenopausal. Aromatase inhibitors usually doesn't work for
premenopausal women. How old was your mom when she's diagnosed? |
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y********3
发帖数: 43 | 16 Bless MM的妈妈，如果骨转移的话，会很痛的。 |
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l*****O
发帖数: 402 | 18 I don't know the chinese name. Aromatase inhibitors have lots of types. Most
popular now is the brand name Femara.
更年期 usually means perimenopause or premenopause. menopause and post
menopause are the same thing. 55 yrs old can not be safely categoried as
menopause for most women unless your mom were done with her period at age 45
or earlier. |
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I****a
发帖数: 407 | 20 ER or PR (+) means tumor's growth some how is dependent on estrogen and it
is a good predictor as one can give either Tamoxifen or aromatase inhibitor
to block the estrogen. Her2/neu + traditionally means that the tumor is more
aggressive and hard to treat. Since Her2/neu monoclone antibody (herceptin)
is introduced, Her2/neu positivity is not that important because we now can
block the her2 pathway with herceptin and even with small tyrosine kinase
inhibitor such as Tykerb.
Overall for your mom... 阅读全帖 |
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t********a
发帖数: 423 | 21 MRI这个检查就可以诊断是否有骨转移，不知道LZ的妈妈在哪里，如果在北京的话，北
医三院或肿瘤医院对骨转移到诊断都是非常准确的。
BLESS |
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s**o
发帖数: 578 | 22 My dad was picked for a ultra sound MRI clinical study to reduce the bones
metastatis pain. It is very helpful |
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a*****y
发帖数: 277 | 25 祝福您妈妈。
ECT就是全身骨扫描，看有无放射性增浓的。
我妈妈和你情况差不多。而且她在国内，我一年多没回去了，好想念她！
可以交流治疗经验，如果您愿意的话。 |
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a*****y
发帖数: 277 | 26 祝福您妈妈。
ECT就是全身骨扫描，看有无放射性增浓的。
我妈妈和你情况差不多。而且她在国内，我一年多没回去了，好想念她！
可以交流治疗经验，如果您愿意的话。 |
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m*********w
发帖数: 17 | 28 MRI and Bone Scan still cannot verify whether it is cancer or not. In US,
they will perfom MRI and Bone Scan to get the general picture first, and
where the cancer is in your body if it is verified. But first in order to
decide whether it is cancer or not, you need to do biopsy - 活检.
I suggest to do biopsy - 活检 ASAP. For the worst case, you can start
radiation treatment and chemo without any further delay.
My bless to your family. |
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l*******e
发帖数: 121 | 29 祝福楼主的妈妈
我不太懂这方面的知识 只有祝福了! big bless! |
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m********h
发帖数: 86 | 31 18F-FDG PET is the best way to tell the bone metastasis. It is highly
sensitive, less false positive. It does affected by inflammary tissue, but
it will give a global view of the disease for whole-body. It is a standard
follow up for monitoring breast cancer recurrence. Strongly recommended. |
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x******n
发帖数: 87 | 33 Bless!!!!
You mom will be fine!!! |
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p***1
发帖数: 200 | 34 我也想问一下，我的母亲去年也被诊断得了乳腺癌。手术，化疗。
诊断：右乳浸润型导管癌 PIINoMo，
免疫组化：ER（－），PR（－），c-erbB-2(＋＋) ，P53(+)，nm23(+)
这些诊断能说明什么？
谢谢了。 |
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s*****g
发帖数: 180 | 36 ECT is sort of bone scan.Usually 99mTc-MDP would be used as a radio-tracer.
It is actually sensitive to bone metastasis. Sometime a PET scan using 18F-
sodium fluoride could also be helpful.
Clear about the diagnosis (the staging of the cancer) is the first step!
Herceptin is an anti-HER2 monoclonal antibody. SERM will be applied to deal
with ER + tumors. |
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t****o
发帖数: 41 | 38 那现在ECT显示有浓聚，下一步应该是什么哪？MRI要到礼拜六才能做。
.
-
deal |
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t****o
发帖数: 41 | 39 刚问清楚了，从2004年开始先是吃了1年多的“法乐通”，英文名是Fareston，药名是
Toremifene，然后因为子宫内膜增厚，又2006的时候做摘除胆囊手术，所以停了一年。
之后吃“弗隆”Femara，来曲唑，Letrozole，吃了2年多的样子吧，后来因为浑身发类
似湿疹的皮肤病，又换成了“瑞宁得”，阿那曲唑片，Anastrozole Tablets。这里“
法乐通”不知道是属于哪类药，似乎是比Tamoxifen好些。后面两个Femara和瑞宁得都
是属于aromatase inhibitor。
另外2004年的诊断和治疗是：
右乳癌，已行改良根治手术。术中病理报告：右乳腺导管内癌（多灶性），基地阴性，
巴结22个全部阴性。化疗5次，分别是： 第一次THP80mg，泰素210mg，第二，三，四
CTX0.8d，THP90mgd，第五次泰素210mgd.
inhibitor
more
herceptin)
can
treatment |
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t****o
发帖数: 41 | 40 再多问一句，ECT和PET CT的区别是什么？
.
-
deal |
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t****o
发帖数: 41 | 41 已经做了ECT了，周六再做MRI，还需要做PET CT嘛？ |
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I****a
发帖数: 407 | 44 If she really is proved having bone metastasis, she should continue be
treated with hormonal therapy although through different drugs with
different mechanism. Just to list a few: she can try steroidal aramatase inactivator Exemestane or estrogen antagonist Fulvestrant or even Megestral acetate. If disease strikes through above treatment and I think sooner or later it is going to, then Her2 targeted therapy coupled with chemotherapy.
Above information is based on if your mom's menstruation had s... 阅读全帖 |
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s*****g
发帖数: 180 | 45 ECT uses single photon emitter such as 99mTc; PET uses positron emitter such
as 18F. The mechanism is different. PET/CT is the fusion of PET and CT.
Usually PET is more sensitive but it is more expensive. As I mentioned, for
bone metastasis, 99mTc-MDP scan (one sort of ECT) is good enough, 18F-FDG/
NaF scan may or may not add value to it. |
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t****o
发帖数: 41 | 46 太感谢了！那为什么国内的大夫看了ECT上面的“轻度浓聚”还说不能确诊？接下来除
了MRI还能做什么啊？
such
for |
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t****o
发帖数: 41 | 47 Thanks a lot. Now the key step is just how to confirm it is or not bone
matastasis. :(
inactivator Exemestane or estrogen antagonist Fulvestrant or even Megestral
acetate. If disease strikes through above treatment and I think sooner or
later it is going to, then
not, ovary ablation with drugs should be tried.
treatment in US in conjunction with all others. |
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m*********w
发帖数: 17 | 48 biopsy - 活检 is the only way to confirm whether it is cancer or not. I know
this from my experience to handle bone matastasis for the family memeber in
US. Don't waste time any more. The doctors won't care much when you want to
do biopsy - 活检.
Megestral |
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t****o
发帖数: 41 | 49 那这种情况应该做哪个部位的biopsy啊？还是说要像前面提到的做CT-guided biopsy从
腰椎里取东西？
know
in
to |
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t****o
发帖数: 41 | 50 btw，her2 targeted therapy是不是就是用herceptin？
inactivator Exemestane or estrogen antagonist Fulvestrant or even Megestral
acetate. If disease strikes through above treatment and I think sooner or
later it is going to, then
not, ovary ablation with drugs should be tried.
treatment in US in conjunction with all others. |
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