R*****G
发帖数: 1665 | 1 As you post the stuffs, you obviously have abrogated your right of privacy,
a posture yielding for attention. Now you get it, so what are you
complaining about? |
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c**********h
发帖数: 496 | 2 每天包办家务，老公还不给办身份的家庭妇女，还有征婚的女同胞们，尤其注意了哦！
英国封建社会的一个女人尚且能有这样的思想，写出这样的文章。而在现代民主的美国
，我们受过的教育胜她百倍，还不能为女权站起来做些力所能及的事情吗？
AFTER considering the historic page, and viewing the living world with
anxious solicitude, the most melancholy emotions of sorrowful indignation
have depressed my spirits, and I have sighed when obliged to confess, that
either nature has made a great difference between man and man, or that the
civilization which has hitherto taken place in the world has been very
partial. I have turned... 阅读全帖 |
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c****t
发帖数: 19049 | 3 THE PACIFIC JOURNAL OF ADAM EWING
Thursday, 7th November—
Beyond the Indian hamlet, upon a forlorn strand, I happened on a trail of
recent footprints.
Through rotting kelp, sea cocoa-nuts & bamboo, the tracks led me to their
maker, a White man,
his trow-zers & Pea-jacket rolled up, sporting a kempt beard & an outsized
Beaver, shoveling
& sifting the cindery sand with a teaspoon so intently that he noticed me
only after I had hailed
him from ten yards away. Thus it was, I made the acquaintance of... 阅读全帖 |
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R*o
发帖数: 3781 | 4 From Constantine To Augustine
As Durant and other historians have pointed out, Constantine never reno
unced his loyalty to the pagan gods. He abolished neither the Altar of Victo
ry in the Senate nor the Vestal Virgins who tended the sacred fire of the go
ddess Vesta. The Sun-god, not Christ, continued to be honored on the imperia
l coins. In spite of the "cross" (actually the cross of the god Mithras) on
his shields and military banners, Constantine had a medallion created honori
ng the Su... 阅读全帖 |
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C****i
发帖数: 1776 | 5 CHAPTER 19
OF THE LAW OF GOD
1. God gave to Adam a law, as a covenant of works, by which he bound him and
all his posterity to personal, entire, exact, and perpetual obedience, prom
ised life upon the fulfilling, and threatened death upon the breach of it, a
nd endued him with power and ability to keep it.
2. This law, after his fall, continued to be a perfect rule of righteousness
; and, as such, was delivered by God upon Mount Sinai, in ten commandments,
and written in two tables: the first fo... 阅读全帖 |
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l**********t
发帖数: 5754 | 6
3. For what if some did not believe? shall their unbelief make the faith of
God without effect?
"
3. What indeed if some, etc. As before, while regarding the Jews as exulting
in the naked sign, he allowed them no not even a spark of glory; so now,
while considering the nature of the sign, he testifies that its virtue (
virtutem, efficacy) is not destroyed, no, not even by their inconstancy. As
then he seemed before to have intimated that whatever grace there might have
been in the sign of circu... 阅读全帖 |
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l**********t
发帖数: 5754 | 7
21. But now the righteousness of God without the law [109] is manifested,
being witnessed by the law and the prophets;
"
21. But now without the law, etc. It is not certain for what distinct reason
he calls that the righteousness of God, which we obtain by faith; whether
it be, because it can alone stand before God, or because the Lord in his
mercy confers it on us. As both interpretations are suitable, we contend for
neither. This righteousness then, which God communicates to man, and
accepts ... 阅读全帖 |
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C*****e
发帖数: 367 | 8 【 以下文字转载自 Church 俱乐部 】
发信人: CCBible (神同在圣经), 信区: Church
标 题: Glossary to the Westminster Confession
发信站: BBS 未名空间站 (Tue Apr 24 21:16:33 2012, 美东)
Glossary to the Westminster Confession
Explanations of all archaic and uncommon words, usages, and expressions, in
the order in which they occur.
Title Confession. n. Public statement of religious beliefs.
1.1 Providence. n. Divine care. Manifest. v. Show. Are they. idiom. T
hey are. Unto. prep. With regard to. Sundry. adj. Separate. D... 阅读全帖 |
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W**N
发帖数: 1037 | 9 历史主义是Marx主张的吗？ ：）
－－－－－－－－－－－－－－－－－－－－－－－－－－
http://en.wikipedia.org/wiki/Historicism
Karl Popper used the term historicism in his influential books The Poverty
of Historicism and The Open Society and Its Enemies, to mean: "an approach
to the social sciences which assumes that historical prediction is their
primary aim, and which assumes that this aim is attainable by discovering
the 'rhythms' or the 'patterns', the 'laws' or the 'trends' that underlie
the evolution of history".[5] Karl Popper w... 阅读全帖 |
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w******e
发帖数: 1187 | 10 I hope I knew this earlier...:)
I guess you are talking about endosomal escape? or chemical conjugation
simply
abrogate the drug property?
I'm hooked with the simplicity of conjugating aptamer with siRNA. both can
achieve certain level of specificity; both can be synthesized in a single
run; the toxicity profile of ONs are widely available due to the gold
rush in anti-sense field... Yet it's a shame that you only have that few
aptamers to choose from (well, only 1 or 2, according to my knowledge |
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a********k
发帖数: 2273 | 11 花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
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D*******8
发帖数: 4 | 12 Please don’t dig me out. I am writing this out of my conscience as a
scientist. We are using, largely, the tax payers’ money to explore
mechanisms underlying diseases that we don’t have a cure, yet. We are doing
this in the hope that little bit knowledge can accumulate till one day we
can find that magic bullet. However, there are people out there, their
purpose is to use these money to achieve their personal fames, sometimes
international ones, totally disregarding our original noble cause. I... 阅读全帖 |
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s******y
发帖数: 28562 | 13 我觉得他的文章的意思就是大部分基因的表达程度都和细胞的活跃程度有关，
所以随便乱抓几个都能看出区别来，但是和癌症的机理基本上就是打酱油的关系。
总体意思就是目前的主流方法找出来的marker不能作为推测机理的起点。
他们在faculty 1000上抱怨说他们这篇文章一共投了4年，前后被六个
顶级杂志据了（他们直接点名的几家估计是对他们态度最糟糕的，哈哈哈）
这里是他们在PLoS Comp Biol 发表的文章的摘要。
Bridging the gap between animal or in vitro models and human disease is
essential in medical research. Researchers often suggest that a biological
mechanism is relevant to human cancer from the statistical association of a
gene expression marker (a signature) of this mechanism, that was d... 阅读全帖 |
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s******y
发帖数: 28562 | 14 我觉得他的文章的意思就是大部分基因的表达程度都和细胞的活跃程度有关，
所以随便乱抓几个都能看出区别来，但是和癌症的机理基本上就是打酱油的关系。
总体意思就是目前的主流方法找出来的marker不能作为推测机理的起点。
他们在faculty 1000上抱怨说他们这篇文章一共投了4年，前后被六个
顶级杂志据了（他们直接点名的几家估计是对他们态度最糟糕的，哈哈哈）
这里是他们在PLoS Comp Biol 发表的文章的摘要。
Bridging the gap between animal or in vitro models and human disease is
essential in medical research. Researchers often suggest that a biological
mechanism is relevant to human cancer from the statistical association of a
gene expression marker (a signature) of this mechanism, that was d... 阅读全帖 |
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p*****e
发帖数: 93 | 15 1.
CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-κB
activation
Brian C. Grabiner1,5, Marzenna Blonska1,5, Pei-Chun Lin1, Yun You1, Donghai
Wang4, Jiyuan Sun1, Bryant G. Darnay2, Chen Dong3, and Xin Lin1,6
2.
MEKK3 is required for lysophosphatidic acid-induced NF-kappaB activation.
Sun W, Li H, Yu Y, Fan Y, Grabiner BC, Mao R, Ge N, Zhang H, Fu S, Lin X,
Yang J.
3.
Bcl10 plays a critical role in NF-κB activation induced by G protein-
coupled receptors
Donghai Wang * , † ... 阅读全帖 |
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l********n
发帖数: 260 | 16 揭露臧敬五在新闻媒体上的谎言——兼评其JCI论文
作者：胆大妄为
方舟子先生，
你好！本人注意到臧敬五在很多新闻媒体上对其作为通讯作者发表在JCI上
的论文加以宣传后，翻阅了这篇论文（1），发现臧敬五胆大妄为，编造谎言，
欺骗中国新闻媒体，应予以揭露。
先看二篇臧敬五在媒体上的宣传：
“骨桥蛋白”是引发类风湿性关节炎的顽凶
新华网上海３月２日电（胡德荣、仇逸）严重影响人类健康和生活质量的类
风湿性关节炎（注：rheumatoid arthritis，RA）研究获得重大突破性进展。我
国科研人员在国际上第一次阐明了骨桥蛋白（注：osteopontin ，OPN）在类风
湿性关节炎发病中的作用，发现“骨桥蛋白”是引发类风湿性关节炎的顽凶，为
治疗类风湿性关节炎找到了临床手段和药物靶点。……
http://www.stcsm.gov.cn/news/detail.asp?pid=64857
我专家突破类风湿关节炎治疗世界难题
上海分院
日前，中国科学院上海生命科学研究院健康科学中心主任臧敬五教授，带领
科研人员完成了“骨桥蛋白在类风湿性关节炎中的病理机制”研究，其论文已刊
登在3月2日出版的... 阅读全帖 |
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S*****s
发帖数: 242 | 17 最早发现Ctla-4的是James Allison？这是谁告诉你的？Pierre Goldstein！连ctla-4
对免疫的抑制功能都是Jeffery Bluestone发现的，这才是关键的发现。这个Jim
Allison是开发抗体的，这个credit要给他。不过这离Lasker也太远了吧？ James
Allison现在是拉上他在MD Anderson的情妇拼命的抢credit，故意误导舆论。这不就有
像你这样被误导成了义务宣传员的？ 建议好好阅读这篇新的Science Letter, 搞清楚
才发言。
https://www.sciencemag.org/content/344/6180/149.1.full
Science 11 April 2014:
Vol. 344 no. 6180 p. 149
DOI: 10.1126/science.344.6180.149-a
LETTERS
Immunotherapy: It Takes a Village
We in the cancer immunology and immunotherapy community are th... 阅读全帖 |
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l**********r
发帖数: 240 | 18 Actually I think it is a tough choice for the firm. Unlike in NYC, clients
here generally can't afford high billing rate. So they kind of use the
billable hours to compensate for that.
I think he could have gone to a top20 firm at that time(Mcdermott?). The
reason that he stayed with this firm is probably because his girlfriend (now
wife) took a job here with another top firm---my guess:)
And my guess is that you are an in-house counsel:) Laid-off possibility is
abrogated since somehow I feel th |
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p*******g
发帖数: 2976 | 19 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
s******i
发帖数: 870 | 20 这才是社会学大家应该干的事儿。
----------------------------------------------------------------------------
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Wallerstein Commentary 239
1 message
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Donna DeVoist Fri, Aug 15, 2008 at 7:18 AM
Reply-To: Commentary Subscribers
To: C*****[email protected]
Please do not reply to the listserv. To correspond with the author, write <
i******************[email protected]>.... 阅读全帖 |
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h***a
发帖数: 312 | 21 来自主题: Medicalpractice版 - GMO http://www.aaemonline.org/gmopost.html
https://www.youtube.com/watch?v=eeW5yUSqdhY
American academy of enviromental medicine
Genetically Modified Foods
According to the World Health Organization, Genetically Modified Organisms(
GMOs) are "organisms in which the genetic material (DNA) has been altered in
such a way that does not occur naturally."1 This technology is also
referred to as "genetic engineering", "biotechnology" or "recombinant DNA
technology" and consists of randomly inserting genet... 阅读全帖 |
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