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发帖数: 27354 | 1 _gen/derivatives/landscape_630/DIY_BIO_SOSA_pg_02web.jpg
A complete lack of formal scientific training has not kept Johan Sosa from
dabbling with one of the most powerful molecular-biology tools to come along
in decades.
Sosa has already used CRISPR, a three-year-old technology that makes
targeted modifications to DNA, in test-tube experiments. Next week, he hopes
to try the method in yeast and, later, in the model plant Arabidopsis
thaliana.
http://www.nature.com/news/biohackers-gear-up-for-gen... 阅读全帖 |
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m**p
发帖数: 2471 | 2 Career Ladder: Xiaoxi Wei
A fascination with organ transplantation inspired this ‘biohacker’ to
cofound her own company
By Taylor C. Hood
Growing up in China with a petrochemical engineer and businessperson father
and a physician mother, Xiaoxi Wei was encouraged to pursue scientific
activities. “My father would often let me take things apart and analyze how
things worked, and my mother would stay by my bed telling me stories from
the children’s encyclopedia when I was sick. I was fascinated by ... 阅读全帖 |
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发帖数: 1 | 3 基因编辑技术对成年人而言，有希望治愈或缓解遗传病，是已经在实验室中折腾了几十
年的基因治疗真正走出实验室，走进临床为大众服务的机会。因为，这一次我们掌握了
强大的工具，能相当准确的进行基因编辑。
这项技术的巨大医疗价值，相信会让该领域有大量金钱持续涌入，无论是来自政府还是
来自私人资本或民间组织，这会让该技术进一步完善，并且让成本大幅度下降。所以，
人们也不用担心这个技术会彻底分裂社会。想想智能手机的普及速度就知道了。我相信
，如今说起来还是高精尖的基因编辑技术，最多二十年也就会变成高中生就能操作的技
术，这样的宿命，在基因测序一事上早就变成现实。
除此之外，世界首例基因编辑婴儿问世，也证明该技术可以用于防止遗传病继续遗传，
当然也可以用它人为制造遗传病，比如这次的操作就是将正常的CCR5基因给突变灭活，
就为了防范HIV。这件事过于魔幻和滑稽，我更想听到的消息是，重度地中海贫血患者
生出了健康宝宝。
当然，从科幻的角度看，这项技术还能用于人类补完。
但鉴于目前我们不知道该怎么补完人类，除非在动物身上先做一系列实验。所以，在补
完人类之前，我们也许先得去补完一下比如黑猩猩。您是不是想起... 阅读全帖 |
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