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全部话题 - 话题: bispecific
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S*****a
发帖数: 63
1
【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Biologics Discovery and Development Positions Available at Abpro Labs in Woburn, MA
关键字: Biologics,Discovery,Development,Antibody,Computational
发信站: BBS 未名空间站 (Wed May 31 20:28:52 2017, 美东)
Multiple Biologics Discovery and Development Positions Available at Abpro
Labs in Woburn, MA
www.abpro-labs.com
To apply please send resume to [email protected]
1. Scientist/Senior Scientist, Antibody Display Technology
... 阅读全帖
S*****a
发帖数: 63
2
【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Biologics Discovery and Development Positions Available at Abpro Labs in Woburn, MA
关键字: Biologics,Discovery,Development,Antibody,Computational
发信站: BBS 未名空间站 (Wed May 31 20:28:52 2017, 美东)
Multiple Biologics Discovery and Development Positions Available at Abpro
Labs in Woburn, MA
www.abpro-labs.com
To apply please send resume to [email protected]
1. Scientist/Senior Scientist, Antibody Display Technology
... 阅读全帖
S*****a
发帖数: 63
3
【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Biologics Discovery and Development Positions Available at Abpro Labs in Woburn, MA
关键字: Biologics,Discovery,Development,Antibody,Computational
发信站: BBS 未名空间站 (Wed May 31 20:28:52 2017, 美东)
Multiple Biologics Discovery and Development Positions Available at Abpro
Labs in Woburn, MA
www.abpro-labs.com
To apply please send resume to [email protected]
1. Scientist/Senior Scientist, Antibody Display Technology
... 阅读全帖
S*****a
发帖数: 63
4
【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Biologics Discovery and Development Positions Available at Abpro Labs in Woburn, MA
关键字: Biologics,Discovery,Development,Antibody,Computational
发信站: BBS 未名空间站 (Wed May 31 20:28:52 2017, 美东)
Multiple Biologics Discovery and Development Positions Available at Abpro
Labs in Woburn, MA
www.abpro-labs.com
To apply please send resume to [email protected]
1. Scientist/Senior Scientist, Antibody Display Technology
... 阅读全帖
S*****a
发帖数: 63
5
Multiple Biologics Discovery and Development Positions Available at Abpro
Labs in Woburn, MA
www.abpro-labs.com
To apply please send resume to [email protected]
1. Scientist/Senior Scientist, Antibody Display Technology
We are seeking an experienced and highly motivated Scientist with strong
hands-on experience in antibody display (phage/yeast) to support discovery
research projects by screening to identify lead candidate therapeutic
antibodies, as well as engineering molecules for improved... 阅读全帖

发帖数: 1
6
【 以下文字转载自 Biology 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Biology
标 题: Protein Chemistry Scientist position available in Woburn MA (转载)
发信站: BBS 未名空间站 (Wed Apr 18 13:56:34 2018, 美东)
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Protein Chemistry Scientist position available in Woburn MA
发信站: BBS 未名空间站 (Wed Apr 18 13:54:49 2018, 美东)
Sr./Scientist, Protein Chemistry
We are looking for an energetic and dynamic hands-on scientist with
initiative and a
collaborative spirit in our protein chem... 阅读全帖
c*********o
发帖数: 1734
7
来自主题: Immigration版 - Review opportunity, 制药
我可以把你推荐给editor,感兴趣的话,尽快PM我。
你需要把你的简单背景发给我, 包括名字,email,现在的organization和title。 还
要在这个journal的reviewer database注册一下。
Title: Thermally induced degradation pathways of three different antibody-
based drug development candidates
European Journal of Pharmaceutical Sciences
ABSTRACT:
Protein-based medicinal products are prone to undergo a variety of chemical
and physical degradation pathways. One of the most important exogenous
stress condition to consider during manufacturing, transport and storage
pro... 阅读全帖
i********n
发帖数: 171
8
来自主题: Immigration版 - 审稿 IF2.0
Please send your request with selected article and CV in your field. if you
have been as reviewer with this journal, please mention your experiences.
Some reviewers has agreed with my previous review invitation, please submit
your comments as soon as possible. thanks,
send your request to [email protected]/* */
1.Sex differences regarding the amelioration of wrinkles due to skin dryness
by the administration of tranexamic acid
2.Preparation, pharmacokinetics and pharmacodynamics of ophthal... 阅读全帖
S*****a
发帖数: 63
9
【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Protein Chemistry Group Leader position available in Woburn MA
关键字: protein chemistry,antibody,biologics
发信站: BBS 未名空间站 (Fri Jul 7 09:36:00 2017, 美东)
We are looking for an energetic and dynamic hands-on leader with initiative
and a
collaborative spirit to serve as a Group Leader in our protein chemistry lab
. This is a fantastic
opportunity to drive antigen/antibody expression, purification, and QA to
support
v... 阅读全帖
d****t
发帖数: 139
10
来自主题: Biology版 - Paper help
Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22611-6.
Chemical generation of bispecific antibodies
Thanks!

发帖数: 1
11
来自主题: Biology版 - 求职三年(2014-2016)
求职三年(2014-2016)
2016年10月26日
前言
十多年前本科毕业就来到了美国,一直没有上过MITBBS。去年准备绿卡,找到了
Immigration版,受益良多,发现这儿有一群跟自己经历很相似的人,重温了当年分享
机经的感觉。在版上闲逛,看到了一些真知灼见的帖子,如longwoodwalk(http://www.mitbbs.com/article_t/Biology/31797101.html),Devonshire01 (http://www.mitbbs.com/article_t/Returnee/13560813.html)和evelynlin (http://mitbbsde.com/article_t1/Military/46400579_46401185_1.html)等,很感触这些对自己的增益。身为千老,对Biology版上战友们的苦闷深切共鸣。近几年一直在生物制药领域找工作,最近感到了一些希望和正能量,献丑跟大家分享。
我本科博士都是化学,博士后生物化学,都是辛苦的方向,是个千老。从博士起所做的
方向一直跟蛋白质,博士后有幸在几个算得上prestigi... 阅读全帖
S*********e
发帖数: 127
12
来自主题: Biology版 - paper help
Elimination of large tumors in mice by mRNA-encoded bispecific antibodies
Christiane R Stadler, Hayat Bähr-Mahmud, Leyla Celik, Bernhard
Hebich, Alexandra S Roth, René P Roth, Katalin Karikó, Ö
zlem Türeci & Ugur Sahin
Nature Medicine (2017)
doi:10.1038/nm.4356
Thanks
G********a
发帖数: 268
13
来自主题: Pharmaceutical版 - bispecific
公司准备在这方面加强实力,招兵买马。有同行的,可以准备跳了。
b*******e
发帖数: 724
14
小分子前途很有限,主要是受技术本身的限制.副作用太强.新的TARGET是有,
EPIGENETICS,CANCER IMMUNO等都是新领域,但就算是好的TARGET,最终成药的概略也是
小于大分子.大分子的研发其实挺成熟的,局限性在TARGET.ADC和BISPECIFIC应该是将来
的大方向.尤其是ADC,T-DM1就是一个例子,这个技术经过十几年的发展,终于步入了成熟
期,不久的未来我们会看到很多ADC药.如果你要选一个方向的话,我会说大分子.
b*******e
发帖数: 724
15
小分子前途很有限,主要是受技术本身的限制.副作用太强.新的TARGET是有,
EPIGENETICS,CANCER IMMUNO等都是新领域,但就算是好的TARGET,最终成药的概略也是
小于大分子.大分子的研发其实挺成熟的,局限性在TARGET.ADC和BISPECIFIC应该是将来
的大方向.尤其是ADC,T-DM1就是一个例子,这个技术经过十几年的发展,终于步入了成熟
期,不久的未来我们会看到很多ADC药.如果你要选一个方向的话,我会说大分子.
b*******e
发帖数: 724
16
来自主题: Pharmaceutical版 - Gilead很猛啊
短期内内是个不错的公司.但他们公司从长远来讲在TECHNOLOGY上面的局限性比较大.因
为主要是小分子,ANTI VIRAL DRUG.这个市场在SHRINK,尤其是HCV,过了2020就没啥
REVENUE了.GENENTECH相对来讲,是INDUSTY里面技术最全面的.MAB,ADC, BISPECIFIC,小
分子都做的不错,长期的发展回更好些.
S*****a
发帖数: 63
17
We are looking for an energetic and dynamic hands-on leader with initiative
and a
collaborative spirit to serve as a Group Leader in our protein chemistry lab
. This is a fantastic
opportunity to drive antigen/antibody expression, purification, and QA to
support
various therapeutic biologics programs while providing leadership to our
discovery efforts.
Responsibilities:
• Set up and run, in a hand-on way, a Protein Chemistry group to
express, purify, and characterize proteins, fusion pr... 阅读全帖
S****u
发帖数: 42
18
来自主题: Pharmaceutical版 - 无标题
Please apply from the Pfizer Website:
https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---
California---Rinat/Scientist--non-PhD---Protein-Engineering_4692599
Pfizer -CID
Pfizer Cancer Immunology Discovery (CID) is a South San Francisco
biotechnology unit within the Oncology division of Pfizer Worldwide Research
& Development, dedicated to doing its part to fulfill Pfizer's mission of
working together for a healthier world. CID is dedicated to developing new
protein and cell-b... 阅读全帖
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