d*********e
发帖数: 3835 | 1 Citizenship Requirement: U.S. or Valid Green Card Holder
Job Duties:
Planning:
• Develop a market-centric strategy for the product or product line,
that includes an analysis of market demand (supported by the Strategic
Marketing Manager and others as needed), customer behavior, competitors,
StandardAero's capabilities and a strategic and market orientation for the
product or product line. Such a plan shall present the evolution of the
product and product portfolio over an appropriate calen |
|
d*********e
发帖数: 3835 | 2 Citizenship Requirement: U.S. or Valid Green Card Holder
Job Duties:
Planning:
• Develop a market-centric strategy for the product or product line,
that includes an analysis of market demand (supported by the Strategic
Marketing Manager and others as needed), customer behavior, competitors,
Company’s capabilities and a strategic and market orientation for the
product or product line. Such a plan shall present the evolution of the
product and product portfolio over an appropriate calendar p |
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P****d
发帖数: 564 | 3 zkss?
I was impressed by the facility and the smoothness of the organization. The
meeting I went to was a bit Chinese-centric (chinese from overseas), but I
guess most new meetings struggle with attracting attendees. |
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w******e
发帖数: 1187 | 4 quite a slap on the face hehe.
The results also show that the contribution of phenotypic screening to the
discovery of first-in-class small-molecule drugs exceeded that of target
-based approaches — with 28 and 17 of these drugs coming from the two
approaches
, respectively — in an era in which the major focus was on target-based
approaches. We postulate that a target-centric approach for first-in-class
drugs, without consideration of an optimal MMOA, may contribute to the
current
high attrition... 阅读全帖 |
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u*********1
发帖数: 2518 | 5 我觉得要考虑几个方面：
1.如何定义“遗传因素比较大”？ 想确定到底是familial还是sporadic，肯定要收集
足够的sample吧。。有时候对于有的疾病sample都很难收集。这不仅是人力，精力，
funding的问题，有的疾病病人死的很快，或者sample本身很少，总是很难碰到一个好
的大的pedigree的
2.NGS技术本身我当然是很看好的了，肯定越来越精确成熟，而且越来越便宜。但到底
能有多便宜？什么时候可以很轻松的给每个人做全基因组测序？read length可以达到
长?（肯定是越长越好）计算机的硬件能跟上NGS数据发展的趋势吗？
3.生物信息分析。我只能说现在的bioinformatic pipeline，除了read alignment和
SNP calling变的非常成熟（不仅sensitivity/specificity很高，而且可以做
population-level的分析），在其他方面，要么很艰难，要么很混乱。就是说无法达成
一个统一大家公认的最好的pipeline，我开发一个方法，你开发一个软件，最后把使用
者都搞的糊里糊涂的。比如indel cal... 阅读全帖 |
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n******7
发帖数: 12463 | 6 我觉得你说到点上了，应该M起来
“4.对基因组，genome biology本身的认识。其实纵然是whole-genome sequencing，我
看大部分的paper也就是先找找coding region/splicing的SNP/indel；或者说大家还是
gene-centric的。现在我们对基因组的认识还很不完善，且不说loci interaction，就
连最基本的每个loci是什么作用都不清楚。很多基因的功能都不知道，而且gene本身的
概念也在被扩充，不断有新的gene被发现，以及各种新型的什么miRNA gene啊，
linkRNAgene被发现。还有很多regulatory region比如被ENCODE给annotate出来。除了
非常明显的罕见的large deletion/duplication，或者一些repeat expansion，我们的
精力还是停留在missense mutation上，因为这个最好解释。而splicing site，或者
regulatory region有一个哪怕是罕见的A到T的突变，请问你能立刻给我解释下这个
rare SNP ... 阅读全帖 |
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m**********n
发帖数: 299 | 7 http://www.ncbi.nlm.nih.gov/pubmed/?term=24014010
1: Garvey WT. New tools for weight-loss therapy enable a more robust medical
model for obesity treatment: rationale for a complications-centric approach.
Endocr Pract. 2013 Sep-Oct;19(5):864-74. doi: 10.4158/EP13263.RA. PubMed
PMID:
24014010.
非常感谢。 |
|
m**********n
发帖数: 299 | 8 包子求助文献一篇
http://www.ncbi.nlm.nih.gov/pubmed/?term=24014010
1: Garvey WT. New tools for weight-loss therapy enable a more robust medical
model for obesity treatment: rationale for a complications-centric approach.
Endocr Pract. 2013 Sep-Oct;19(5):864-74. doi: 10.4158/EP13263.RA. PubMed
PMID:
24014010.
非常感谢。 |
|
m**********n
发帖数: 299 | 9 包子求助文献一篇
http://www.ncbi.nlm.nih.gov/pubmed/?term=24014010
1: Garvey WT. New tools for weight-loss therapy enable a more robust medical
model for obesity treatment: rationale for a complications-centric approach.
Endocr Pract. 2013 Sep-Oct;19(5):864-74. doi: 10.4158/EP13263.RA. PubMed
PMID:
24014010.
非常感谢。 |
|
u*********1
发帖数: 2518 | 10 其实translational research这个词，一方面强调了研究应用化，另一方面也算个空话
可以钻很多空子。我眼里的translational其实可以囊括basic research以外的所有研
究，比如clinical research/biostat/药物/engineering，甚至包括我自己这种用病人
样本但还是基础手段做disease研究的。总之最后目的还是治病救人；要translational
肯定离不开basic science；但一味basic最后也就很容易陷入拼figure，纠结detail的
泥潭。
但我要说，从不同角度看同一个主题，还真是不一样。
比如neuroscience vs neurology，过去刚入行的时候觉得这俩应该肯定有很多
overlapping吧，但XX-ology就真的是想方设法，动用各种手段来了解disease本身，一
个有影响力的MD老板，手上有样本有资源，就可以招各路神仙，有做genetics的，做
bioinformaitcs/测序的，做RNA的，做protein structure的，做老鼠的，做signaling
path... 阅读全帖 |
|
发帖数: 1 | 11 Competing endogenous RNAs: a target-centric view of small RNA regulation in
bacteria
Lionello Bossi & Nara Figueroa-Bossi
Nature Reviews Microbiology (2016) doi:10.1038/nrmicro.2016.129
Published online 19 September 2016
Am J Respir Crit Care Med. 2016 Sep 20. [Epub ahead of print]
Translating MicroRNA Biology in Pulmonary Hypertension: It Will Take More
Than "miR" Words.
Chun HJ1, Bonnet S2, Chan SY3.
my Email: [email protected]/* */
Thank you very much. |
|
发帖数: 1 | 12 Admera Health is seeking aScientist I to join our Custom and RUO Services
team. This is a position that works closely with customers and in the lab
in order to effectively manage the customer interaction with Admera Health.
Title: Scientist I
Location: South Plainfield, NJ
Purpose of the Position
Useyour extensive scientific knowledge in molecular biology with creativity
and technological skills to establish new methods,provide new services, and
troubleshoot. T... 阅读全帖 |
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c*******e
发帖数: 150 | 13 For the concentration in finance for example:
faculty research: Johnson > Fuqua > Yale SOM
MBA placement: Yale > Johnson >= Fuqua
alums influences and networks: Yale >= Johnson > Fuqua
location: New Haven > Ithaca > Durham (NYC-centric)
not sure about the case for other tracks like management consulting,
strategies, accounting, etc. Yet I suspect that Yale SOM still contribute
the most graduates to McKinsey and BCG as compared with Fuqua or Johnson |
|
B******1
发帖数: 9094 | 14 Blame all these to Wall Street and those people who changed pharma from a
science-based organization to business-centric enterprise. |
|
发帖数: 1 | 15 Introduction
Meritco Services, a fast-growing China-focused strategy consulting firm, was
founded by ex-McKinsey consultants in late 2009 and now has presence in
Shanghai, Beijing and Chengdu with a team of over 80 consultants.
Since the very beginning of our establishment, Meritco has been dedicated in
building a very strong healthcare practice with a mission to serve leading
corporate and PE clients in the areas of pharmaceuticals, medical device,
and healthcare service in China. Our topics ... 阅读全帖 |
|
ls
发帖数: 33 | 16 麻烦大家帮忙转贴 多谢
Call for Papers
DANMS 2008
3rd International Workshop on Distributed Autonomous Network Management
Systems
Co-located with Globecom 2008, New Orleans, USA
30 November, 2008
http://www.danms.org
The DANMS workshop series focuses on distributed and autonomous principles
for network management and applications of those principles in network
design. This year's workshop emphasizes Service Centric Network Management
considering the impact on the system, across the whole information flow f |
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h**l
发帖数: 168 | 17 hehe, my humble comments:
3G根本不可能承担大规模的使用量，大量使用，带宽就会拥堵，更不要说现在推的上网
本、数据卡，这是要3G的命。
This is simply a question of bandwidth/user proportion problem. If this
professor can say it to 3G, I can also say it to 2G, 1G, WIFI, and whatever
bandwidth-limited network services. lol.
I think the underlying assumption is that the average thoughtput per user
will significantly increase as 3G is data centric and more data-hungry
applications will be available to end-users, thus aggravating the problem.
三个3G运营商资费 |
|
T******T
发帖数: 3066 | 18 BTW jeamouse, I believe our system manager has a req for Senior System
Hardware Engineer(FPGA emulation centric),some board level design work (20%)
, but requires extensive XV5 based SOC emulation experience (80%). PM me
your resume if you are interested. |
|
P**********c
发帖数: 3417 | 19 新浪微薄feature多，但是技术上不见得比twitter有什么优势。国内的网站有用户没traffic. 微薄这么火才排29就是例子。Twitter是媒体centric, 主要用来传播消息，主要的tweets来源WSJ, Bloomberg什么的。而微博更像是换了一个界面的facebook，还是大家在上面贴照片. Twitter traffic全球排第9，每天的tweets数量远远超过新浪微薄。要想赚广告钱，traffic是王道。traffic越大，大家点广告的概率越大。facebook和人人网看着差不多的东西，facebook现在一年赚1个billion, 人人网还在亏钱。
互联网还算是个新领域，国内这块是挺强的，但是也没必要盲目捧杀，更没必要因为这个就说互联网没技术含量。说实在的，技术含量这东西听上去很牛，实际上很虚。有没有技术含量，看赚多少钱是唯一的标准。因为至少对私企来说，大家都还是普遍承认赚钱是他们共同的唯一的目标。你的技术含量既然那么高，就要有敢要价的魄力。别人技术含量低，有本事你就去分一杯羹。说其他的都是枉然。
twitter |
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j******g
发帖数: 1098 | 20 凡是TG也能做的，立马变成白菜，立马不属于高科技。
燃汽轮机如此，weibo也如此。
twitter的zombie account也不少。
说的难听点，twitter连贴图片的功能都搞不出来，看张WSJ的都成问题。
只用赚钱多少来衡量技术含量明显不合适。
facebook肯定赚的比mips，amd 或者那个threeleaf多多了，
facebook 米犹敢忽悠TG的中投来参股，但是连threeleaf这样的小破公司，华为这辈子
都买不到。
traffic. 微薄这么火才排29就是例子。Twitter是媒体centric, 主要用来传播消息，
主要的tweets来源WSJ, Bloomberg什么的。而微博更像是换了一个界面的facebook，还
是大家在上面贴照片. Twitter traffic全球排第9，每天的tweets数量远远超过新浪微
薄。要想赚广告钱，traffic是王道。traffic越大，大家点广告的概率越大。facebook
和人人网看着差不多的东西，facebook现在一年赚1个billion, 人人网还在亏钱。
这个就说互联网没技术含量。说实在的，技术含量这东... 阅读全帖 |
|
c****p
发帖数: 6474 | 21 如果从traffic/可用用户数来看呢？
微博和人人只有国内的几亿人在用（包括从国内出去的学生），后者的主要群体更只有
在校大学生。
我觉得这两个人和国外这些差别也和国家的信息建设有关。
个人体验来说，我感觉人人上的东西（应用）比facebook丰富得多，但是有用的信息的
重复率太高了。
没上过tweets，不知道是什么样子。【 在 PixelClassic (如梦) 的大作中提到: 】
traffic. 微薄这么火才排29就是例子。Twitter是媒体centric, 主要用来传播消息，
主要的tweets来源WSJ, Bloomberg什么的。而微博更像是换了一个界面的facebook，还
是大家在上面贴照片. Twitt
这个就说互联网没技术含量。说实在的，技术含量这东西听上去很牛，实际上很虚。有
没有技术含量，看赚多少钱是唯一的标准。因为至少对私企来说，大家都还是普遍承认
赚钱是他们共同的唯一的目 |
|
a*****n
发帖数: 2499 | 22 August 16, 2016, 8:07 pm EDT
Cisco is laying off upwards of 14,000 employees, representing nearly 20
percent of the networking giant’s global workforce, according to multiple
sources close to the company.
San Jose, Calif.-based Cisco is expected to announce the cuts within the
next few weeks, as many early retirement package plans have already been
offered to employees, said sources. Cisco is set to announce its fourth
fiscal quarter results after the market closes tomorrow.
The heavy cuts, whi... 阅读全帖 |
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c**********a
发帖数: 92 | 23 The Company:
Faraday Future (FF) is a California-based mobility company, leveraging the
latest technologies and world’s best talent to realize exciting new
possibilities in sustainable transportation. We’re producing user-centric,
technology-first vehicles to establish new paradigms in human-vehicle
interaction. We’re not just seeking to change how our cars work – we’re
seeking to change the way we drive. At FF, we’re creating something new,
something connected, and something with a global impac... 阅读全帖 |
|
发帖数: 1 | 24 Introduction
Meritco Services, a fast-growing China-focused strategy consulting firm, was
founded by ex-McKinsey consultants in late 2009 and now has presence in
Shanghai, Beijing and Chengdu with a team of over 80 consultants.
Since the very beginning of our establishment, Meritco has been dedicated in
building a very strong healthcare practice with a mission to serve leading
corporate and PE clients in the areas of pharmaceuticals, medical device,
and healthcare service in China. Our topics ... 阅读全帖 |
|
a*a
发帖数: 1295 | 25 The personal statement:
Many of us find these as hard to read as you do to write. We seldom use the
statement as an important discriminator. That said, there are rare personal
statements that so succeed in painting a picture of you as an interesting
person that I will really want to meet you. Unfortunately, more of you,
concerned to be noticed, worry me by self-aggrandizing ego-centric prose. If
your file is iffy to start with, this will put you in the rejected pile. We
are looking for team-play |
|
m********4
发帖数: 607 | 26 Winning Their Trust----Anand K. Parekh, M.D., M.P.H.
The ranks of the U.S. medical profession will soon grow by 16,000 physicians
, as the class of 2011 graduates from medical schools throughout the country
. These new physicians will go on to receive graduate medical training that
is superb by global standards. Once in practice, they will be encouraged to
uphold high quality standards through licensing and certification,
activities of specialty societies, and participation in a growing array of... 阅读全帖 |
|
b******6
发帖数: 19 | 27 We are hiring for a foreign-invested hospital located in Shanghai, China.
This hospital is currently the largest teritary level, with a total
investment of USD 500 million. The hospital is conveniently located in Xuhui
District, the city center of Shanghai, with approved tertiary care capacity
of 500 licensed beds (246 beds in phase one).
From design to operation, they seek to employ the world’s best practices to
be an internationally recognized medical institution in China, providing
high-quali... 阅读全帖 |
|
M*********m
发帖数: 2024 | 28 You must have seen this sort of things before. For free electron gas, if you
apply magnetic field to it, the orbital angular momentum around the magnetic
field is quantized. Since the electron number is conserved, so the density of
state changes from a parabolic to steps. It was proposed by L.D. Landau in
1930 and was measured by de Haas and van Alphen at the same year. For HTSC,
the electrons are considered mainly confined in 2D cuprate layer, and
therefore the Landau levels are co-centric circ |
|
S******y
发帖数: 1123 | 29 湾区的data scientist 的job market 今年年初已来 依然红火
三四年前 融资三千万算是techcrunch 上的大新闻
现在比比皆是。融资一轮就上亿的公司最近也好几个了
科技公司刚开始都是请core engineer搭架子 做两年数据多了就需要data scientist /
data analyst 提供insights, guidance, 及对产品的建议, predictive model
prototype and support productionization
趋势是social，mobile， cloud, ads platform
机会挺多 竞争也多
湾区公司请人 上花的时间不计其数
见过一个小公司请一个工程师面了竟有三四十人 有时我也不理解
有点花街的风气 local candidates 多; scale of economy 面试的人走马灯一样
所以找工作 换工作 的同学不要打没准备的仗~
Python Hive R 最基本三板斧一样不少 big O notation
简单的算法要知道一点更好
machine learning concep... 阅读全帖 |
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m********4
发帖数: 607 | 30 Winning Their Trust-----by Anand K. Parekh, M.D., M.P.H.
The ranks of the U.S. medical profession will soon grow by 16,000 physicians
, as the class of 2011 graduates from medical schools throughout the country
. These new physicians will go on to receive graduate medical training that
is superb by global standards. Once in practice, they will be encouraged to
uphold high quality standards through licensing and certification,
activities of specialty societies, and participation in a growing arra... 阅读全帖 |
|
m********4
发帖数: 607 | 31 Winning Their Trust-----by Anand K. Parekh, M.D., M.P.H.
The ranks of the U.S. medical profession will soon grow by 16,000 physicians
, as the class of 2011 graduates from medical schools throughout the country
. These new physicians will go on to receive graduate medical training that
is superb by global standards. Once in practice, they will be encouraged to
uphold high quality standards through licensing and certification,
activities of specialty societies, and participation in a growing arra... 阅读全帖 |
|
z*****2
发帖数: 498 | 32 三年来从Allscript换到Centricity,现在又换到Epic。 老了，经不起折腾了，还是回
到老本行Linux。 |
|
s*********o
发帖数: 567 | 33 工作压力不大，薪资中等，training 机会比较多。部门招的中印研究生，都陆续先给
办了H1b 再给办绿卡。
http://aetna.jobs/new-york-ny/digital-media-analyst-sas-r-pytho
Req ID: 29049BR POSITION SUMMARY Aetna s Data Science organization is
growing! Aetna is building leading data science capabilities to drive our
business transformation in this exciting period in the health care industry.
We are seeking passionate, data-hungry consultants and analysts at all
levels to harness cutting-edge tools and technology to transform health care
. Come join... 阅读全帖 |
|
|
发帖数: 1 | 35 Introduction
Meritco Services, a fast-growing China-focused strategy consulting firm, was
founded by ex-McKinsey consultants in late 2009 and now has presence in
Shanghai, Beijing and Chengdu with a team of over 80 consultants.
Since the very beginning of our establishment, Meritco has been dedicated in
building a very strong healthcare practice with a mission to serve leading
corporate and PE clients in the areas of pharmaceuticals, medical device,
and healthcare service in China. Our topics ... 阅读全帖 |
|
z*******n
发帖数: 1034 | 36 http://gamerboom.com/archives/83475
发布时间：2014-04-23 11:04:44 Tags：巴西数字游戏市场,手机上瘾者,美国智能手机
用户,苹果IAP标签
1）据MacRumors报道，苹果已采取步骤更好地区分含有IAP内容的游戏和应用，在App
Store榜单和列表中增加了一个新的IAP标签。
苹果去年3月在应用商店每个页面添加了一个“Offers IN-App Purchases”的声明，最
近又通过iOS 7.1.1为这些应用增加了标签，当应用出现在苹果App Store分类页面以及
热门榜单之上时就会显示其含有“In-App Purchases”的标签。
IAP label(from gamasutra)
IAP label(from gamasutra)
由于许多用户是直接通过App Store列表和分类页面来寻找应用，所以苹果此举有利于
最小化用户在“不知情”中因IAP机制而被收费的情况。
今年1月，苹果已同意向那些能够证实自己信用卡被子女误刷而遭遇损失的用户支付达
3250万美元的退款。
2）尼尔森最新数据显示，各个年龄段的多数美... 阅读全帖 |
|
z*******n
发帖数: 1034 | 37 By Bogdan Petrovan June 21, 2014
samsung gear neo fit smartwatches aa 4
Samsung will show its first Android Wear device at Google I/O next week,
says a new report.
According to CNET, which cites people familiar with the matter, Samsung will
be the third Android Wear partner to introduce a smartwatch powered by
Google’s wearable-centric operating system. Samsung’s device will be
similar to its Gear smartwatches, which are running Tizen, according to the
sources.
Samsung is said to be developing a... 阅读全帖 |
|
z*******n
发帖数: 1034 | 38 There Are 506,742 Mobile Developers in the Three Major App Stores: And They
Don’t Play Together
Marketing & Promotion
Tuesday, July 29, 2014
- 4,769 views
Posted 2 days ago by STUART PARKERSON
There Are 506,742 Mobile Developers in the Three Major App Stores: And They
Don’t Play Together
Google Play has 292,796 developers. The iOS App Store has 271,509 developers
. The Amazon Appstore has 31,247 developers. That’s a lot of developers -
506,742 to be exact.
Where did we get those ... 阅读全帖 |
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N*****S
发帖数: 1551 | 39 这种方法理论可行，可是转接电话可能不太牢靠，就是说很多电话都接不到。从我个人
经验来的。
我当年也是转到GV上，然后付费到skype上买了一个skype number并付了年费，GV-》
Skype-》国内联通。结果经常接不到电话。
当然，我不知道这个call centric到底有多牛。不过大家可以自己掂量掂量。 |
|
C******g
发帖数: 2930 | 40 The Q&A session following the Free Realms-centric keynote speech, delivered
earlier today by Sony Online Entertainment president John Smedley at GDC
Austin, contained a hopeful tidbit for those looking to play the
aforementioned free-to-play MMO on their consoles. When we asked about the
release window for the PS3 version of Free Realms, Smedley cheekily replied,
"I'm wondering, too!" He then added, "It's next year sometime, toward the
middle of the year."
During his speech, Smedley also address |
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l******n
发帖数: 11737 | 41 【 以下文字转载自 EGames 俱乐部 】
发信人: lalaphin (orpheus), 信区: EGames
标 题: New NGP details emerge at private event
发信站: BBS 未名空间站 (Sat Feb 5 18:37:14 2011, 美东)
http://www.eurogamer.net/articles/2011-02-04-new-ngp-details-em
During a presentation to around 20 UK developers at its headquarters in
London yesterday, Sony shared a wide range of information about its new
handheld platform, revealing significant new details on launch plans,
hardware specifications, networking features and more.
One attendee, sp... 阅读全帖 |
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r*******1
发帖数: 4394 | 42 换新的rotor(centric reqular blank)，以前的pads (Hawk HPS)还有70%，觉得扔掉太
可惜。但是pads上有些pattern，有没有办法把pads 打磨平啊？ |
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r*******1
发帖数: 4394 | 43 刚自己换了centric 的 rotor 和 HPS 的pads，按照6小停3大停的程序bed in。不知道
之后还要磨合吗？有人说800mile之内不急停.
友情提示：brake这活还是让mechanic干吧，把rotor从hub上卸下来废了牛劲了，还把
手给扭了，最后用20lb的大榔头生生给震下来了。 |
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d***a
发帖数: 13752 | 44 昨天自己把SUV的冬季胎换下来，把四季胎换上去。开车十多年，
还是第一次自己动手换胎。说说作为一个新手的心得体会：
1. 换胎的准备工作不算小，准备了jack/jack stand, tire
chock, torque wrench, 十字wrench, 把lug nuts adapters,
lug nut lock adapter找出来。这些少一个都不好使。
2. 换的注意事项也不少。换每个wheel时，先要把每个lug
nut松开，再把车jack起来，取下lug nuts，卸下冬季胎，
放上四季胎，拧上lug nuts，松开jack把车放下来，再用
torque wrench拧紧lug nuts。松开和拧紧lug nuts有一定
的次序，松开第一个后，再松开对面一个。我的wheel有五
个lug nuts，要按一个star pattern来松开和拧紧。
3. 要注意胎是不是symmetric/asymmetric以及
directional/non-directional。我的四季胎是symmetic
和non-directional，这种最简单。要把四个wheel编上
号，下... 阅读全帖 |
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e********y
发帖数: 350 | 45 tirerack.com上有很多,你可以从tirerack上看你车可以fit的刹车编号,然后google下
看看有没有更便宜的. 我觉得akebono, centric, brembo和stoptech都很不错,别买
hawk的就行了 |
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w*******y
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Here's the link: Link:
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w*******y
发帖数: 60932 | 48 Wii Trideca Gaming Tower $10 Free Ship
Link:
http://www.bedbathandbeyond.com/product.asp?SKU=16844080&RN=222
Keep your favorite Wii games neat, tidy and organized with this Wii Trideca
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and Wii-centric form factor. Constructed of 100% recyclable plastic. One-
year limited warranty ... 阅读全帖 |
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