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q*******1
发帖数: 2 | 3 please see below detailed JD:
Executive Director of Discovery Biology
Location: Beijing
Key activities: Oversee biology-related research and drug discovery
activities to execute departmental strategies and meet deliverables.
Successful candidate is also responsible for biology resource allocation,
recruitment and the professional development of biology staff.
Requirements:
• Ph.D. in biology, cell biology, immunology, biochemistry,
virology, pharmacology or a related field with an ou... 阅读全帖 |
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H**********J
发帖数: 351 | 4 我在招聘Assay Head/DMPK Head/Translational Medicine Leader/Biomarker/统计等
等 |
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M******A
发帖数: 15 | 5 We are looking for a Scientist or Senior Scientist for a leading pharma
company's R&D center in Shanghai, China.
Main Responsibilities:
1. Works within a multi-disciplinary team of scientists to ensure successful
delivery of antiviral drug discovery program from exploratory to lead
optimization stage;
2. Initiate and execute research activities related to identification and
characterization of antiviral targets;
3. Design and implement various in vitro and in vivo studies to elucidate
molecular ... 阅读全帖 |
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M******A
发帖数: 15 | 6 We are looking for a Scientist or Senior Scientist for a leading pharma
company's R&D center in Shanghai, China.
Main Responsibilities:
1. Works within a multi-disciplinary team of scientists to ensure successful
delivery of antiviral drug discovery program from exploratory to lead
optimization stage;
2. Initiate and execute research activities related to identification and
characterization of antiviral targets;
3. Design and implement various in vitro and in vivo studies to elucidate
molecular ... 阅读全帖 |
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E*******2
发帖数: 131 | 7 看什么岗位吧。最近看到诺华上海招DMPK Scientist，要求0－3年工作经验。然后碰巧
看到一个猎头发了类似信息，只是隐去了公司名字，然后说年薪30－60万。 |
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J****S
发帖数: 15 | 8 Pls contact: d******[email protected] for more information
Requirements:
1、BS in Clinical Medicine/Basic Medicine from top universities
2、Overseas Ph.D in lifescience(no clincal experiences need) / or have
clinical trial management experiences(no further degree needed)
Responsibilities:
1、Work as a CTL on Medium to High complexity studies including multi-
country / multi-centre trials and lead the Clinical Trial Team (CTT) in
development of the protocol and related documents.
*CTL will involve the ... 阅读全帖 |
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C****3
发帖数: 162 | 9 联系人：Echo Zhong +8618621600641
E-mail: [email protected]
/* */
Thanks
大分子类研发、工艺开发、生产运营：
1. 抗体研发&工艺开发总监/高级总监（上下游技术均可）
2. 细胞培养研发&工艺开发总监/高级总监
3. 抗体技术支持高级总监（熟悉抗体研发和生产技术，上下游均可）
4. 抗体生产高级总监（上下游技术均可）
5. 高级运营总监（熟悉大分子工厂运营管理，抗体、蛋白、疫苗类均可）
6.纯化研发&工艺开发总监（熟悉生物类药物纯化技术）
7.制剂研发&工艺开发总监（熟悉生物类药物制剂技术）
8. Bioassay and Biological Characterization Director (Lead bioassay
development activities.Accountable for bioassay applications for early
and late stage development programs,bioassay qualific... 阅读全帖 |
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s****l
发帖数: 513 | 10 一直都有人做。日本做的稍微好一些。
这一套流程非常冗长和繁琐，需要的技术很多。如果只是lab做做，发发文章，就不用
看我下面写的了。
这个idea一点也不稀奇，难在如何用有限的资源和技术来实现。难点很多：
中草药的提取很复杂，分离和鉴定不是一般实验室可以做的。药物筛选是需要分离和鉴
定的物质，而且不是一堆混合物。有天然产物化学背景的人知道，大部分天然产物是非
常复杂的结构，还包括了不少手性中心。除非可以好运筛选到活性足够，毒性够低，
DMPK性质够好的分子。这种情况几乎是买彩票中大奖。那么接下来很实际的一个问题是
，lead optimization。Medicinal chemist是不喜欢来给复杂的天然产物来做SAR的，
比起其他Lipinski's rule的分子来说，工作量绝对是5-10倍都不止的，而且你拿到结
果量是差不多的。很可能没合成几百个分子，lab就没grant或者公司就shift mission
了。不少中草药分子很大的一个问题是动物毒性比较大。在这个浮躁的社会（不止中国
，其他地方也是），很少人愿意去做这种事情。 |
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T****u
发帖数: 424 | 11 同楼上两位
不仅如此，还有你用的溶剂也有影响，常说的DMPK
一般从1mpk-100mpk,看下PK,T1/2
如果不是新药的，查查文献参考一下 |
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H**********J
发帖数: 351 | 12 目前Open职位：
DMPK-Group Leader (Roche R上海)；
Bioanalytical Head（Roche R上海）；
CMC Biologics(Roche R上海)；
Medicinal Chemistry (Roche R 上海)；
Clinical Pharmacology Expert(Roche R 上海)；
Clinical Pharmacologist(Roche R北京)；
Analytical Science-CI(Roche R 上海)；
Quality and Compliance Manager-CMC（Roche R 上海）
CMC-Formulation Group Leader（Roche R 上海）
Clinical Scientist-Onc/CNS/Rheumatology（Roche D 上海/北京）
MA & ME –Onc (Bayer R & D 北京)
有有兴趣的同学吗？ |
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b******e
发帖数: 3348 | 13 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: bitworse (关白), 信区: Pharmaceutical
标 题: HPLC 和 MS的工作机会
发信站: BBS 未名空间站 (Tue Apr 17 15:34:09 2012, 美东)
recruiter跟我联系的，仪器界的大公司，在Boston, 谁有兴趣，发resume到bitworse@
gmail.com
1. field service engineer in the Boston area (Waters experience preferred)
2. DMPK applications scientist (>1 year company experience) |
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s********s
发帖数: 579 | 15 【 以下文字转载自 Returnee 讨论区 】
发信人: smileashes (Pb), 信区: Returnee
标 题: 中国医药生物化学产业对美国的就业冲击
发信站: BBS 未名空间站 (Sun Oct 21 21:55:09 2012, 美东)
最近和普华永道一起搞了一个调查,摸清了中国医药生物化学产业的现状.
有几个数据很可怕：
1。整个这个产业的产能过剩40%,开工率完全不足，还有逐渐增加的趋势.
2。上海去年新增后缀为生物医药或者生物化学公司超过4900家。
其实上海的门槛还是比较高的（也没有什么政府投资），很多小地方政府疯狂的吸引这
个方面的海龟(很多是被lay off的bench labor，或者是没有network的老千)回来创业
，前期政府还参与投资个100-200万，基本上就便宜了卖仪器和玻璃设备的。
3。中国FTE的价格的白热战，已经导致严重的低利润，甚至印度公司都举步维艰了。
国内一线的大公司的价格已经降到6万多美金一个人了（从高峰的10万，到后来的8万,
直接下来）根据我的测算，这个价格的利润已经低于15%了。
当年印度公司通过5万美金的FTE拿活... 阅读全帖 |
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l*****7
发帖数: 2844 | 16 http://cen.acs.org/articles/90/i43/AstraZeneca-Teams-Two-Major-
AstraZeneca Teams Up With Two Major Research Contractors
By Jean-François Tremblay
Department: Business
Keywords: CRO, R&D outsourcing, layoffs, China, dmpk, in vivo
The British drugmaker AstraZeneca has established two research outsourcing
agreements as part of the restructuring of its R&D organization.
In Beijing, the Chinese pharmaceutical R&D contractor Pharmaron will set up
a dedicated research center for AstraZeneca tha... 阅读全帖 |
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j**********8
发帖数: 65 | 17 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: jonathan9158 (double), 信区: Pharmaceutical
标 题: 湾区大药厂的 temp 位置，做bioanalysis，有人感兴趣么？
发信站: BBS 未名空间站 (Wed Oct 16 22:56:37 2013, 美东)
六个月的temp职位，是Research Associate，在DMPK department，有可能延长到一年
。要求有较强的小分子定量LC/MS经验，会sample preparation，包括plasma，blood，
CSF，Urine 和 tissues。熟悉 Watson LIMS。
不sponsor H1B。最好是本地candidate，学历本科或硕士，工作经验两年以上最好。
感兴趣的话，发简历到我信箱 w****[email protected]
谢谢！ |
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M********e
发帖数: 212 | 18 【 以下文字转载自 Immigration 讨论区 】
发信人: Macrophage (男神 总教主), 信区: Immigration
标 题: 求BIOANALYSIS, PK 方面的REVIEWERS 各3名
发信站: BBS 未名空间站 (Wed May 7 10:21:47 2014, 美东)
我有二篇PAPER 想发在Journal of Chromatography B. 和Drug Metabolism and
Disposition. 求搞BIOANALYSIS， HPLC, 药物代谢， DMPK的同学 做REVIEWER. 我把
文章SUBMIT的时候名字推荐给编委他做决定， 最好博后以上吧。 请把名字， title
， 公司院校名和EMAIL 信息EMAIL 给我， qhuangclass AT gmail.com。最好以前有在
这2个杂志发过文章， 有记录（注册有了REVIEWER帐号就更好）。 我会把我的文章摘
要寄给你， 你填一下为啥要选你做REVIEWER. 其他领域的就不要了，我想EDITOR也不
会考虑。 谢谢。 |
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c******1
发帖数: 61 | 20 anyone interested please contact recruiting HR Carol Huang for more
information
[email protected]
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/* ]]> */
Senior Synthetic Chemist 化学合成高级研究员
Key responsibil... 阅读全帖 |
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x**********0
发帖数: 33 | 21 我们公司招有经验的LC-MS分析Principle Scientist。地点在南加尔湾。有兴趣的发信
给我。
job description:
A principle scientist who will play a key role in new drug characterization
and analysis using LC-MS in research and development. Major responsibility
include assay development and troubleshooting for in vitro and in vivo drug
metabolism and pharmacokinetic (DMPK)studies in support of drug candidate
selection and IND-enabling studies.
PH.D in chemistry with more that 10 years pharmaceutical experience using LC
/MS. |
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c*****a
发帖数: 845 | 22 上海招聘俩名生物药工艺研发副总监（ Cell Line 和cell
culture俩个方向 ），要求博士3年以上相关工作经验，欢迎自荐和推荐。Redrock.wu@
p-link.cn,Cell/Wechat: 13564288425
外资药企招聘化学工艺安全评估的高级研究员，要求应届博士，化学专业，熟悉有机合
成，英语流利，懂工艺研发更佳，工作地江苏苏州，欢迎自荐和推荐。Redrock.wu@p-
link.cn,Cell/Wechat: 13564288425
外企做药企上海招聘DMPK项目管理人员，最低要求博士2年企业相关工作经验，英语流
利，项目沟通协调和项目管理能力强，欢迎自荐和推荐。[email protected]
/* */, Cell
/Wechat: 13564288425 |
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H**********J
发帖数: 351 | 23 如题
国内药厂有3个Informatics职位招聘，越看越觉得跟药物研发背景关系不大，跟IT倒是
有巨大关系~大家帮忙看看哈~谢谢啦~
1，Early Development Informatics
Qualifications: M.Sc., Ph.D. or equivalent in Computer Science with a
pharmacology or medical background, or an M.Sc., Ph.D. or equivalent
Pharmacology or Medicine with a strong computer science background, in
addition to experience within the Pharmaceutical or Biotech industry.
Working as a member of Early Development Informatics within Pharma Research
and Early Development Informatics at the Roc... 阅读全帖 |
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j******8
发帖数: 12 | 24
1,
药学版块贴过了，TKS~
医生可以考虑Medical的职位ha：ME(Physician, Protocol Design, Phase 3-4); MA、
MSL（方向：肿瘤、CNS、风湿免疫、CV、内分泌等）拜耳&罗氏D
罗氏R主要是肿瘤、病毒、DMPK、Clinical Pharmacology、Medicinal Chemistry等方
面的职位;
大家愿意看机会的可以电话我：021-5155 8984；国内现在机会比较多，诺华和阿斯利
康职位马上也出来了；
Scientist 最好是已经做完博士后的；中级职位要求海外背景+3年以上Industry经验；
高级职位要求海外背景+8年以上Industry经验；
关于薪酬及行业情况，等我自己的账号可以发帖了之后，我再跟大家沟通；O(∩_∩)O |
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R*j
发帖数: 248 | 25 The research in this lab perfectly fits the company's position in DMPK or
TOX department. Big pharma particularly wants to know how parent drug or
bioactive metabolites covalently bind to macromolecules (e.g., proteins)
leading to toxicity. (I should point out that thus far no clear evidence
demonstrate the binding of drug to macromolecules absolutely results in
toxicity.).
Go for it! I guarntee you'll get lots of interviews from big pharmas after
graduation.
tissues" |
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b**u
发帖数: 2761 | 26 是么？我以前做的和DMPK有点关系，我不知道楼主说的chemical在体内代谢对身体的伤
害做的是哪方面？ |
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b*******e
发帖数: 724 | 27 We don't need you to "educate" us, because what you said is "go ask somebody
" rather than discussing the merits about the original post.
What you said is not correct:
1. Generic drugs are cheaper, often much cheaper than brand names. they use
the least expensive alternative available, and their cost of manufacturing
is much lower.
2. The 80-125% given by the author is quite accurate. The same range was
given by a chief DMPK person from TEVA, the laregest generic drug maker, in
a speech about ge |
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p***y
发帖数: 239 | 28 尽管PK/PD水平一般，大部分Ph.D 毕业都可以到大公司的DMPK部门找到工作。主要是这
几年这个方向工作机会比较多吧。但是还在努力往前走的教授很少了，有的自己开公司
，有的要退休，对research 和publication不关心了。据说每年发了10个offer,有三分
之二的人接受offer。
many |
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I******t
发帖数: 1619 | 29 请在美国的大侠们不吝赐教啊！专业是药分，DMPK之类的。。。 |
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E***n
发帖数: 308 | 30 your background sounds fine. Gain as much DMPK experience as possible. I
believe you will get a job after 2 yrs postD.
what's the difference between LC-MS/MS定量 and simple LC quantification?
),
time
profit
y)，目前就是做一些 pre-clinical and
ADME |
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o****3
发帖数: 5100 | 31
from
and
This
Very good position. Is he doing all right? 16 year assosiate professor is a
big concern if you ask me. |
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K******S
发帖数: 10109 | 32 这回文怎么看的那么别扭呢？上个ID的话没有看出什么啊？收到刺激了？
who
this
they
and |
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o****3
发帖数: 5100 | 33 I am not sure you picked the right person to fight. I am in industry but not
in ADME field. So I don't know too much about it. At least in big pharma,
people care where you came from, especially now.
I hope that chinese here can find a nice boss who is also helpful for future
job looking. But you just don't want to postdoc a couple of years and could
not find a recommendation letter for your next job/postdoc. |
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s**********r
发帖数: 330 | 34 My department is DMPK, but the general hiring process should be quite
similar. |
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px
发帖数: 853 | 35 CRO 有CRO的skill set. CRO做DMPK的一样好进pharmaceutical. 经济差的年头， CRO
可滋润了。 |
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k*****1
发帖数: 1 | 36 请教一下这位前辈,我在申请研究生,
毒理和药理在那边的发展怎么样?比起DMPK呢？
我现在在选择学校和方向，对于这个行业，什么层次的学校值得去呢？
谢谢啦 （^_^）
的. |
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o*****9
发帖数: 61 | 37 DMPK 当然热拉. 越牛的老板越好.学校 比如北卡, 华声顿大学,家周大学... |
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s********s
发帖数: 579 | 38 Covance再过两年肯定要大裁员，
中国的CRO都在建tox,DMPK,报价最多Covance 30％的价格。
Covance的好日子快到头了。 |
|
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s**********r
发帖数: 330 | 40 I don't know how to answer this. PK/PD's role is very important in DMPK,
and normally their jobs are quite secure. But that's my impression. To my
knowledge, there are quite a few famous IDs on this board, maybe they can
post their 2 cents?? |
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c***a
发帖数: 38 | 41 In my company, most of the clinical PK/PD guys are also compound directors
for the DMPK, which is a pretty good career path. |
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i******a
发帖数: 143 | 42 回到原来的话题：
大分子分析现在很多department都需要吧，like DMPK, biologics, some biomarker
group. 有谁知道大分子分析在这些部门的就业情况吗〉？那些公司，哪些部门？
thanks for input |
|
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w********g
发帖数: 447 | 44 俺做，但是工业界好像不怎么care这个东西，比DMPK肯定差多了 |
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f*******r
发帖数: 78 | 45 agree
what about PK/PD, DMPK？ higher or lower than 药剂学? |
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y**g
发帖数: 197 | 46 我还没工作过，所以说的不一定对。
我觉得，PKPD group in the R&D of pharm industry 不需要做实验，你可以google一
下招聘广告，没有要求做bench work的。但有可能你需要设计实验，比如是bolus/
infusion给药，decided the location/frequency/timing of the samples.
就我所知，真正有PKPD的药学院不多，涉及的程度不一样（PKPD, DMPK,CLINICAL
PHARMACUTEICAL SCIENCE). 总之你最好了解PKPD的基本概念，设计模型，有一点统计
知识，会用winnolin/nonmem/splus etc. 就差不多了。
我不清楚这个专业到底好不好找工作。很多公司没有这部门，即使有人数也不多，不能
跟FORMULATION的比。FDA十几年前有了关于PKPD的规定，一个好处是可以少做些实验/
临床，省钱，所以很多公司招人，当时学BME的搞模型的也可以进去。 |
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h******r
发帖数: 294 | 47 公司要大裁人了，上周Director已经发话说我们可能要被砍掉。现在看看自己只能找找
CRO的工作了。有谁知道一些在NJ的做DMPK bioanalysis 的CRO 啊？谢谢！ |
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l******t
发帖数: 2243 | 48 so everybody touches small molecules in those sites get laid off? discovery,
DMPK, formulation...?
(
molecule)
from |
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c********g
发帖数: 1106 | 49 似乎可以申请DMPK的工作。PharmPK mailing list经常有招这类位置的信息。 |
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T*****t
发帖数: 761 | 50 有个职位非常match 我的background. 不知道有没有人在DMPK, 可以帮递简历的. 不甚
感激. |
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