E*****m 发帖数: 25615 | 1 http://news.discovery.com/human/embryonic-stem-cells-trials.html?print=true
First Human Embryonic Stem Cell Trial Begins
The landmark trial could one day lead to a breakthrough in the treatment of
spinal cord injuries.
Thu Oct 14, 2010 11:50 AM ET | content provided by Karin Zeitvogel, AFP
Doctors have begun the first tests of human embryonic stem cells in patients
, treating a man with spinal cord injuries in a landmark trial of the
controversial process, the Geron Corporation said Monday.
The ... 阅读全帖 |
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k*****d 发帖数: 177 | 2 带友发文,请勿回站内,谢谢~
以下为全文:
I am rotating in a lab and struggling with the chick embryonic neural tube
injection. I have
already practised for at least 5 times and still could not get it. Now I can
see the neural tube
under the dissection microscope, but I feel really hard to blow and do the
injection. I think the
main problem I have is my failure to dip the micropipette in a correct way.
Or maybe I did not
blow in the correct time point, or maybe the pipette does not have a proper-
sized hole. I feel |
|
s*r 发帖数: 2757 | 3 只是批准可以实验
http://www.nytimes.com/2010/07/31/health/research/31stem.html?ref=us
from DIA daily
The New York Times (7/31, B1, Pollack) reported on the front of its Business
Day section that the FDA has approved "the world's first authorized test in
people of a therapy derived from human embryonic stem cells." The clinical
trial "could offer the first glimpse of the safety and possible
effectiveness of a technology that has been hailed for its vast medical
promise but also embroiled in political and |
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h*****G 发帖数: 113 | 4 human embryonic stem cell differentiated的细胞cell surface marker staining
需要block Fc receptor吗?
如果需要,一般怎么做?
谢谢。 |
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X******n 发帖数: 914 | 5 谁有RBPJ deficient embryonic stem cell line, 求合作。
请站内联系。 |
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y****g 发帖数: 94 | 6 本人fresh phd一枚, 现在开始找博士后。 一直对embryonic stem cells的研究很感
兴趣。 大家知道湾区做这一块的rising star有哪些实验室吗?谢谢。 |
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y****g 发帖数: 94 | 7 不是不愿意做, cancer太复杂了。 现在cancer stem cell 在solid tumor里面似乎也
没有很好的研究体系。 所以不敢去做。 个人对embryonic stem cell和developmental
biology比较感兴趣。而且ES cell的应用性比较强。 |
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P********r 发帖数: 92 | 8 叹口气,居然又退化到靠读新闻才知道 the advancement in medical research.
真是新年新气象,Embryonic stem cell breakthrough -- 用在病人上啦!How
exciting. (嗯,晚上要读下文献了)
http://www.cnn.com/video/?hpt=hp_c2#/video/health/2012/01/23/ex
breakthrough.cnn
When would the doctors prescribe 'stem cells'? Or any product related with
stem cells? :-) |
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f**********g 发帖数: 2252 | 9 $1,700,000 Funding of NeoStem's Very Small Embryonic-Like Stem Cells Being
Developed to Treat Osteoporosis Recommended by the Department of Defense
Peer Reviewed Medical Research Program
41 minutes ago - PRN
PR NewswireNeoStem, Inc. (NYSE Amex: NBS) ("NeoStem" or the "Company"), an
international biopharmaceutical company with operations in the U.S. and
China, today announced that its FY2010 Technology/Therapeutic Development
Award application number PR101055 has been recommended for funding by t... 阅读全帖 |
|
f**********g 发帖数: 2252 | 10 $1,700,000 Funding of NeoStem's Very Small Embryonic-Like Stem Cells Being
Developed to Treat Osteoporosis Recommended by the Department of Defense
Peer Reviewed Medical Research Program
41 minutes ago - PRN
PR NewswireNeoStem, Inc. (NYSE Amex: NBS) ("NeoStem" or the "Company"), an
international biopharmaceutical company with operations in the U.S. and
China, today announced that its FY2010 Technology/Therapeutic Development
Award application number PR101055 has been recommended for funding by t... 阅读全帖 |
|
发帖数: 1 | 11 12月26日 事实的真相
以前我们分析过,Augusta, GA 只是这个人体基地的一个点,而且我们也追踪到还有一
个点在加州。那么经过更多的分析,显示事实的真相可能是如此。这些地下通道是很久
以前就存在的,是为了战争或避难用的,后来在南北战争中,又充当奴隶逃跑到北方的
通道。那么在后来的后来,就被一些别有用心的人充当了非法活动的场地。而到了80年
代后,日本人就加入进来,把其改造成了一个军事,人体实验基地,成了报复美国的一
种手段。当然,我也强调历史和解,仇恨和解,但要在正确的认知,悔改下的和解。如
果一边在屠杀受害者,一边高谈和解,并千方百计掩盖事情真相的曝光,这不是悔改的
表现,最多是转移了屠杀的目标,我们不能原谅罪恶势力彼此勾结下的和解。根据分析
,这个基地的入口就在Deerfield, ILLinois. 世界每一个人都是这个基地的受害者,
都是这些大药厂的受害者,受害者以亿为单位来计算。你们很可能都在不知不觉中受到
了他们的伤害,请把信息传达到世界每一个角落,让我们一起携手和世界上最邪恶的势
力做顽强的斗争,他们现在还在屠杀无辜的受害者,每天在我家里杀人。请你们和我站
在... 阅读全帖 |
|
发帖数: 1 | 12 【Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH D005368
[edit on Wikidata]
Filariasis is a parasitic disease caused by an infection with roundworms of
the Filarioidea type.[1] These are spread by blood-feeding black flies and
mosquitoes. This disease belongs to the group of d... 阅读全帖 |
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发帖数: 1 | 13 12月27日 为什么我要替中国辩护
我要替中国辩护,并不是因为我是一个中国人,而是因为我知道中国就和这世界上绝大
数的国家一样,虽然有很多丑陋的现象,但是他们是受害者。就
象这个犯罪集团里很多的人一样,他们来自各种种族,他们可能充当了工具,但他们不
是制造这一切,谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂,他们只是打工者,他们只是按照各种雇主提供的配方来生产,他们并不知道
他们会产生怎样的后果。或者这些工人知道后果,但他们只是奴隶,他们又如何去改变
这一切? 所以,当我的调查不断往前推进的时候,不可避免地会涉及各国的企业,但
这并不表明是针对这个国家或这个国家的人民,而是针对一种社会现实和丑陋现象。就
拿菲律宾来说,菲律宾是一个犯罪猖獗的国家,有很多犯罪分子,但是菲律宾人民却是
这个集团的受害者,他们/她们被绑架,沦为了牺牲品,人体实验对象。一个日本人,
强奸上千名菲律宾女孩,却没有受到惩罚。以前我也提到过,有20个国家的名单,这20
个国家的人民其实都是受害者。现在他们把矛头对准中国,或许仅仅是因为我揭示了他
们图害世界人民的内幕,而我是一个中国人的缘... 阅读全帖 |
|
发帖数: 1 | 14 12月27日 为什么我要替中国辩护
我要替中国辩护,并不是因为我是一个中国人,而是因为我知道中国就和这世界上绝大
数的国家一样,虽然有很多丑陋的现象,但是他们是受害者。就
象这个犯罪集团里很多的人一样,他们来自各种种族,他们可能充当了工具,但他们不
是制造这一切,谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂,他们只是打工者,他们只是按照各种雇主提供的配方来生产,他们并不知道
他们会产生怎样的后果。或者这些工人知道后果,但他们只是奴隶,他们又如何去改变
这一切? 所以,当我的调查不断往前推进的时候,不可避免地会涉及各国的企业,但
这并不表明是针对这个国家或这个国家的人民,而是针对一种社会现实和丑陋现象。就
拿菲律宾来说,菲律宾是一个犯罪猖獗的国家,有很多犯罪分子,但是菲律宾人民却是
这个集团的受害者,他们/她们被绑架,沦为了牺牲品,人体实验对象。一个日本人,
强奸上千名菲律宾女孩,却没有受到惩罚。以前我也提到过,有20个国家的名单,这20
个国家的人民其实都是受害者。现在他们把矛头对准中国,或许仅仅是因为我揭示了他
们图害世界人民的内幕,而我是一个中国人的缘... 阅读全帖 |
|
发帖数: 1 | 15 12月28日 仔细阅读以下文章
或许这些文章可以告诉你们孩子被伤害病毒的答案。
Astellas Pharma 应该和这些人体实验有莫大的关系!
Founded 2005; 11 years ago
Headquarters 2-5-1, Nihonbashi-Honcho, Chūō-ku, Tokyo 103-8411, Japan
Key people Yoshihiko Katakana
(President and CEO)
Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH ... 阅读全帖 |
|
发帖数: 1 | 16 12月27日 为什么我要替中国辩护
我要替中国辩护,并不是因为我是一个中国人,而是因为我知道中国就和这世界上绝大
数的国家一样,虽然有很多丑陋的现象,但是他们是受害者。就
象这个犯罪集团里很多的人一样,他们来自各种种族,他们可能充当了工具,但他们不
是制造这一切,谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂,他们只是打工者,他们只是按照各种雇主提供的配方来生产,他们并不知道
他们会产生怎样的后果。或者这些工人知道后果,但他们只是奴隶,他们又如何去改变
这一切? 所以,当我的调查不断往前推进的时候,不可避免地会涉及各国的企业,但
这并不表明是针对这个国家或这个国家的人民,而是针对一种社会现实和丑陋现象。就
拿菲律宾来说,菲律宾是一个犯罪猖獗的国家,有很多犯罪分子,但是菲律宾人民却是
这个集团的受害者,他们/她们被绑架,沦为了牺牲品,人体实验对象。一个日本人,
强奸上千名菲律宾女孩,却没有受到惩罚。以前我也提到过,有20个国家的名单,这20
个国家的人民其实都是受害者。现在他们把矛头对准中国,或许仅仅是因为我揭示了他
们图害世界人民的内幕,而我是一个中国人的缘... 阅读全帖 |
|
m***f 发帖数: 1622 | 17
扯淡呢,看看高最近两年发表的文章吧
CELL STEM CELL, JBC, STEM CELL, PNAS,都是很不错的
就这样还不能PROMOTION? 在美国都可以tennure了
1. Wu T., Wang H., He J., Kang L., Jiang Y., Liu J., Zhang Y., Kou
Z., Liu L., Zhang X., Gao S. (2011) Reprogramming of trophoblast stem
cells into pluripotent stem cells by Oct4. Stem Cells 2011 Feb 8.
[Epub ahead of print].
2. Kang L., Wu T., Tao Y., Yuan Y., He J., Zhang Y., Luo T., Kou Z.,
Gao S. (2010) Viable mice produced from 3-factor induced pluripotent
stem (iPS) cells through tetrapl... 阅读全帖 |
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l****z 发帖数: 29846 | 18 看看这个吧,应该更快更有疗效.
Embryonic Cloning Shows Promise in Diabetes Treatment
Healthy Stem Cells Extracted From Embryonic Clone and Changed Into Cells
That Produce Insulin
For the second time in recent weeks researchers said they used cloning
technology on adult tissue, rather than from a fetus or infant, to create
stem cells that potentially could be used to treat a range of diseases.
Researchers said Monday they created an embryonic clone of a 32-year-old
woman with diabetes, extracted healthy stem ce... 阅读全帖 |
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t*******d 发帖数: 2570 | 19 embryonic stem cell取材于人工受精产生的囊胚。囊胚是胚胎发育大概有100个左右细
胞。人工受精的过程一般是取很多个受精卵,人工受精,然后在体外培养到囊胚期,再
植入到母体里。由于人工受精和体外培养的过程中有失败的几率,所以体外培养的囊胚
数量总是超过最后植入母体内的数量。多于的培养的囊胚怎么办?现在大多的办法是把
他们冰冻起来,但是这些囊胚大多数再也不会被用来植入到母体里。而且再囊胚被冰冻
过几年后,这些囊胚也不能再被用做植入母体里,因为这时候囊胚的质量也因为冰冻的
时间太长而下降了。这时候,这些囊胚就会被销毁。
想用冰冻的囊胚来做embryonic stem cell的科学研究人员会向保存这些囊胚的机构提
出申请用冰冻的囊胚来提取embryonic stem cell。保存囊胚的机构会向这些囊胚的父
母申请批准捐献冰冻的囊胚来做科学研究。在拿到了父母的批准下冰冻的囊胚才会被用
来提取embryonic stem cell。
所以说如果这些囊胚不被用来做科学研究,大多数仍然会被销毁。每年自然销毁的囊胚
数目远超过用来提取embryonic stem cell的囊胚数目... 阅读全帖 |
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n********k 发帖数: 2818 | 20 This is a smart, very focused and productive one I have heard from people
working with him...XD Wang's first student was even more impressive if I am not too old:) and several from HJ Song's lab also have impressive records, A and P from this board both have impressive records in pretty shoret time too...
BTW, to upbeat/Q a bit for those (including myself) who may feel depressed now)....Nothing particularly/unusually, Pretty much decent intelligence, strong motivations/working/person habits/... 阅读全帖 |
|
发帖数: 1 | 21 读了一下这篇文章,不喜欢这种研究思路,不能够称之为科学。
该实验室主页上面所挂出来的以下一些文章中,有很多引用率非常的低。
ROCKII inhibition promotes the maturation of human pancreatic beta-like
cells. Nature Communications. 2017 Academic Article GET IT
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates
that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.
Cell Stem Cell. 2017 Academic Article GET IT
A Modular Platform for Differentiation of Human PSCs into All Major
Ectodermal Lineages. Cell Stem Cell. ... 阅读全帖 |
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C****g 发帖数: 2220 | 22 真是“大道之行简也”。。。
Summary
Differentiated cells can be reprogrammed to an embryonic-like state by
transfer of nuclear contents into oocytes or by fusion with embryonic stem (
ES) cells. Little is known about factors that induce this reprogramming.
Here, we demonstrate induction of pluripotent stem cells from mouse
embryonic or adult fibroblasts by introducing four factors, Oct3/4, Sox2, c-
Myc, and Klf4, under ES cell culture conditions. Unexpectedly, Nanog was
dispensable. These cells, which we desi... 阅读全帖 |
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A********e 发帖数: 354 | 23 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
发帖数: 1 | 24
Download pdf published by SfN (Chapter from 'The History of Neuroscience in
Autobiography, Volume 8' edited by Larry R. Squire)
Yuh-Nung Jan's CV
Lily Jan's CV
Yuh-Nung Jan and Lily Jan
Birth
Family History and Growing Up
National Taiwan University
The Hiking Trip to Shitou in the Spring of 1967
Graduate School Application
Graduate Study at Caltech (1968锟974)
Seymour Benzer Lab (1974锟977)
Steve Kuffler锟絪 Lab at H... 阅读全帖 |
|
p*******g 发帖数: 2976 | 25 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
G****a 发帖数: 10208 | 26 【 以下文字转载自 Biology 讨论区 】
发信人: toptip (土翁), 信区: Biology
标 题: 从骨科医生到诺贝尔奖-山中伸弥的研究历程
发信站: BBS 未名空间站 (Wed Oct 17 00:04:30 2012, 美东)
引言
山中伸弥(Shinya Yamanaka)获得诺奖已经有几天了,虽然两年前在听完他的讲座后
我兴致很高地写了两篇文章,这些天我却没有多少动力再写一篇完整的文章来介绍他的
工作。
我一直对中国现在还盛行的规划性科研,应用导向型科研耿耿于怀。这些所谓的重大项
目在立项的当初对目标/前景写得宏大无比,之后却通常草草收场。如果那些重大项目
真的能实现立项当初的用意,那诺贝尔奖早就在中国遍地开花了。广大科研人员都觉得
这种运行模式是一个笑话,饶毅、施一公等大牛也重炮轰击,但是分钱游戏还在进行着
。而公众,包括相当一部分科研人员也并不了解科研的自身规律,总是一再地问做基础
研究有什么用。
Shinya Yamanaka的成功是典型的小实验室自由探索的成功。他的成功再一次提示,有
相当多的科学突破是不可预测的。如果中国有大批优质的小实验室得到稳... 阅读全帖 |
|
O***n 发帖数: 13127 | 27 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
a********k 发帖数: 2273 | 28 花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
|
s******y 发帖数: 28562 | 29 美国联邦巡回上诉法庭昨天拒绝一些组织要求停止干细胞研究资金的诉求。
美国政府在布什时代对胚胎干细胞的研究限制甚严,不允许联邦资金用于
新的胚胎干细胞的研究。奥巴马上台后放松了此限制。有些组织认为这个
会导致摧毁胚胎的事情发生(也就是堕胎),所以对此进行了诉讼。
此诉求被下层法院驳回之后,上诉后又被上诉庭驳回。但是初步估计对此的
法律纠纷绝不会就此而止。
http://www.washingtonpost.com/politics/appeals-court-panel-says
Appeals court panel says federally funded embryonic stem cell research can
continue
By Associated Press, Published: August 24
WASHINGTON — A federal appeals court on Friday refused to order the Obama
administration to stop funding embryonic stem cell researc... 阅读全帖 |
|
t****p 发帖数: 1504 | 30 引言
山中伸弥(Shinya Yamanaka)获得诺奖已经有几天了,虽然两年前在听完他的讲座后
我兴致很高地写了两篇文章,这些天我却没有多少动力再写一篇完整的文章来介绍他的
工作。
我一直对中国现在还盛行的规划性科研,应用导向型科研耿耿于怀。这些所谓的重大项
目在立项的当初对目标/前景写得宏大无比,之后却通常草草收场。如果那些重大项目
真的能实现立项当初的用意,那诺贝尔奖早就在中国遍地开花了。广大科研人员都觉得
这种运行模式是一个笑话,饶毅、施一公等大牛也重炮轰击,但是分钱游戏还在进行着
。而公众,包括相当一部分科研人员也并不了解科研的自身规律,总是一再地问做基础
研究有什么用。
Shinya Yamanaka的成功是典型的小实验室自由探索的成功。他的成功再一次提示,有
相当多的科学突破是不可预测的。如果中国有大批优质的小实验室得到稳定的资助,那
么类似的科学突破就会随机但是必然地产生。从这种意义上讲,展示Shinya Yamanaka
在研究过程中的这种随机性和必然性,向公众科普科研活动是如何进行的,是值得我花
一点时间的。
解析Shinya Yamanaka发现诱导干细胞(iPS... 阅读全帖 |
|
t****p 发帖数: 1504 | 31 引言
山中伸弥(Shinya Yamanaka)获得诺奖已经有几天了,虽然两年前在听完他的讲座后
我兴致很高地写了两篇文章,这些天我却没有多少动力再写一篇完整的文章来介绍他的
工作。
我一直对中国现在还盛行的规划性科研,应用导向型科研耿耿于怀。这些所谓的重大项
目在立项的当初对目标/前景写得宏大无比,之后却通常草草收场。如果那些重大项目
真的能实现立项当初的用意,那诺贝尔奖早就在中国遍地开花了。广大科研人员都觉得
这种运行模式是一个笑话,饶毅、施一公等大牛也重炮轰击,但是分钱游戏还在进行着
。而公众,包括相当一部分科研人员也并不了解科研的自身规律,总是一再地问做基础
研究有什么用。
Shinya Yamanaka的成功是典型的小实验室自由探索的成功。他的成功再一次提示,有
相当多的科学突破是不可预测的。如果中国有大批优质的小实验室得到稳定的资助,那
么类似的科学突破就会随机但是必然地产生。从这种意义上讲,展示Shinya Yamanaka
在研究过程中的这种随机性和必然性,向公众科普科研活动是如何进行的,是值得我花
一点时间的。
解析Shinya Yamanaka发现诱导干细胞(iPS... 阅读全帖 |
|
w********h 发帖数: 12367 | 32 【 以下文字转载自 Biology 讨论区 】
发信人: toptip (土翁), 信区: Biology
标 题: 从整型医生到诺贝尔奖-山中伸弥的研究历程
发信站: BBS 未名空间站 (Wed Oct 17 00:04:30 2012, 美东)
引言
山中伸弥(Shinya Yamanaka)获得诺奖已经有几天了,虽然两年前在听完他的讲座后
我兴致很高地写了两篇文章,这些天我却没有多少动力再写一篇完整的文章来介绍他的
工作。
我一直对中国现在还盛行的规划性科研,应用导向型科研耿耿于怀。这些所谓的重大项
目在立项的当初对目标/前景写得宏大无比,之后却通常草草收场。如果那些重大项目
真的能实现立项当初的用意,那诺贝尔奖早就在中国遍地开花了。广大科研人员都觉得
这种运行模式是一个笑话,饶毅、施一公等大牛也重炮轰击,但是分钱游戏还在进行着
。而公众,包括相当一部分科研人员也并不了解科研的自身规律,总是一再地问做基础
研究有什么用。
Shinya Yamanaka的成功是典型的小实验室自由探索的成功。他的成功再一次提示,有
相当多的科学突破是不可预测的。如果中国有大批优质的小实验室得到稳... 阅读全帖 |
|
p*******g 发帖数: 2976 | 33 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
b********n 发帖数: 38600 | 34 Scientists think they know why snakes get two penises and people only get
one
http://www.washingtonpost.com/news/speaking-of-science/wp/2014/
Researchers may have figured out why different species develop different
kinds of genitalia. In snakes and reptiles, the genitals grow to mimic leg
buds — producing twin organs. In humans, the genitals grow to mimic a tail
bud — so the penis ends up as a single structure.
In a study published today in Nature, researchers focused on the difference
between s... 阅读全帖 |
|
n****3 发帖数: 543 | 35 求转让审稿机会,我的背景如下,附上发表list和email: j*****[email protected]
恳请直接emai直接联系
I have worked as research associate for almost six years in the field of
Molecular and cellular biology and immunology. I have published original
research papers in several peer-reviewed journals such as Blood, Plos one,
Experimental Cell Research, Reproduction, Transgenic Research,
Differentiation, Cell Biology International, and Histology Histopathology.
I have also helped Cellular & Molecular Immunology journal to review two
ma... 阅读全帖 |
|
n****3 发帖数: 543 | 36 求转让审稿机会,我的背景如下,附上发表list和email: j*****[email protected]
恳请直接emai直接联系
I have worked as research associate for almost six years in the field of
Molecular and cellular biology and immunology. I have published original
research papers in several peer-reviewed journals such as Blood, Plos one,
Experimental Cell Research, Reproduction, Transgenic Research,
Differentiation, Cell Biology International, and Histology Histopathology.
I have also helped Cellular & Molecular Immunology journal to review two
ma... 阅读全帖 |
|
n****3 发帖数: 543 | 37 来自主题: Immigration版 - 求审稿机会 求转让审稿机会,我的背景如下,附上发表list和email: j*****[email protected]
恳请直接emai直接联系
I have worked as research associate for almost six years in the field of
Molecular and cellular biology and immunology. I have published original
research papers in several peer-reviewed journals such as Blood, Plos one,
Experimental Cell Research, Reproduction, Transgenic Research,
Differentiation, Cell Biology International, and Histology Histopathology.
I have also helped Cellular & Molecular Immunology journal to review two
ma... 阅读全帖 |
|
n****3 发帖数: 543 | 38 求转让审稿机会,我的背景如下,附上发表list和email: j*****[email protected]
恳请直接emai直接联系
I have worked as research associate for almost six years in the field of
Molecular and cellular biology and immunology. I have published original
research papers in several peer-reviewed journals such as Blood, Plos one,
Experimental Cell Research, Reproduction, Transgenic Research,
Differentiation, Cell Biology International, and Histology Histopathology.
I have also helped Cellular & Molecular Immunology journal to review two
ma... 阅读全帖 |
|
j*********o 发帖数: 237 | 39 【 以下文字转载自 Biology 讨论区 】
发信人: justdengtao (老男孩), 信区: Biology
标 题: 求推荐epigenetic或stem cell方面的review
发信站: BBS 未名空间站 (Fri Aug 7 11:40:00 2015, 美东)
先多谢了!!
Tao Deng,Ph.D
Email: [email protected]
/* */
Research Fellow
National Cancer Institute
National Institutes of Health
Summary of Research Experience:
Deep understanding of epigenetic regulations, including DNA methylation,
histone modifications and chromatin dynamics
Rich experience on mouse embryonic stem cell manipulation
Full hands-on exp... 阅读全帖 |
|
n****3 发帖数: 543 | 40 求转让审稿机会,我的背景如下,附上发表list和email: j*****[email protected]
恳请直接emai直接联系
Jianjun Shi, PhD
Dept. Of Cancer Biology
The Scripps Research Institute
130 Scripps Way, C214
Jupiter, FL 33458, USA
Phone (561)228-3241
Fax 561-228-3058
I have worked as research associate for almost six years in the field of
Molecular and cellular biology and immunology. I have published original
research papers in several peer-reviewed journals such as Blood, Plos one,
Experimental Cell Research, Reproduction, Transgenic Researc... 阅读全帖 |
|
j*********o 发帖数: 237 | 41 【 以下文字转载自 Biology 讨论区 】
发信人: justdengtao (老男孩), 信区: Biology
标 题: 求推荐epigenetic或stem cell方面的review
发信站: BBS 未名空间站 (Fri Aug 7 11:40:00 2015, 美东)
先多谢了!!
Tao Deng,Ph.D
Email: [email protected]
/* */
Research Fellow
National Cancer Institute
National Institutes of Health
Summary of Research Experience:
Deep understanding of epigenetic regulations, including DNA methylation,
histone modifications and chromatin dynamics
Rich experience on mouse embryonic stem cell manipulation
Full hands-on exp... 阅读全帖 |
|
H********g 发帖数: 43926 | 42 胎儿期我们其实有两个心,后来合并成一个心
胎儿期我们其实只有一个眼睛,后来分成两个眼睛
(待证实)
Interestingly, when we are in the embryonic stage of development, we
actually do have two hearts. The heart primordia (which describes the stage
of the heart's development) in the embryonic stage is actually two hearts,
which eventually fuse together into one heart with four chambers.
Embryologists in the 1920s and '30s kept the heart primordia from fusing in
embryonic frogs, and the frogs that grew up developed two hearts. The same
also goes for... 阅读全帖 |
|
j*****d 发帖数: 787 | 43 I am curious if we can do the following short-cut transformations:
Mouse Embryonic Fiberblast (MEF) ===>>> mouse embryonic neural stem cells
Mouse Embryonic Fiberblast (MEF) ===>>> mouse cancer-like cells (without
extra expression of oncogenes)
each of two needs to start with MEF.
anybody can help (and link) ? |
|
n********k 发帖数: 2818 | 44 What an AMAZING woman! seriously!! I vote her to be a next Nobel laureate
and a first Chinese and it is a girl too....
http://english.cas.cn/accessory/twows4th/twowsaward/201006/t20100627_55793.html
Professor Fanyi Zeng was born in 1968. She received her B.A. in University
of California San Diego, CA, USA in 1991. In 2005, she got her Ph.D in
University of Pennsylvania, PA, USA.
Professor Zeng has led a research team that has made substantial and long-
lasting contributions to the developmental ... 阅读全帖 |
|
y******8 发帖数: 1764 | 45 才开张的新所吧。在北大,所是和学院平行的单位,据我所知,北大给新的所都会给一个5年一个亿的启
动支持。
夫妻店开的好才是好,学校也不用担心培养的人才什么时候为了家庭原因就飞走了。另
外,这个所的人才引进不错啊。这一位在千青中也是翘楚。
132 汪阳明 男 1979年12月 北京大学 生命
科学 2006年02月毕业于[美国]伊利诺伊大学厄巴纳-尚佩恩分校 [美国]加州大
学旧金山分校 博士后
1: Wang Y, Blelloch R. Cell cycle regulation by microRNAs in stem cells.
Results
Probl Cell Differ. 2011;53:459-72. PubMed PMID: 21630156.
2: Wang Y, Blelloch R. Cell cycle regulation by MicroRNAs in embryonic stem
cells. Cancer Res. 2009 May 15;69(10):4093-6. Epub 2009 May 12.... 阅读全帖 |
|
s******y 发帖数: 28562 | 46 Blind' mice eyesight treated with transplanted cells
Lead researcher, Prof Robin Ali , explains the behaviour of blind mice in
the water maze test. Video filmed and produced by UCL and Moorfields
Hospital
Related Stories
British scientists have restored the sight of blind mice by transplanting
light-sensitive photoreceptor cells into their eyes.
The work is a step towards a new treatment for patients with degenerative
eye diseases.
Scientists at University College London Institute of Ophthalmolo... 阅读全帖 |
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G********e 发帖数: 528 | 47 Thank you very much!
It seems that if I want to bypass embryonic lethality, it is a candidate. If
people have been using tissue specific systems, they would be better than
whole body.
I have something in my mind before I want to start it.
If a gene of interest is known critical for embryonic development, is it
really important to bypass the embryonic stage and look at the phenotypes of
loss of function after the mice are fully developed? I think so, but it
seems not many people publish studies u... 阅读全帖 |
|
h******y 发帖数: 351 | 48 终于克隆人了。
Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
Cell, 15 May 2013
doi:10.1016/j.cell.2013.05.006
Reprogramming somatic cells into pluripotent embryonic stem cells (ESCs) by
somatic cell nuclear transfer (SCNT) has been envisioned as an approach for
generating patient-matched nuclear transfer (NT)-ESCs for studies of disease
mechanisms and for developing specific therapies. Past attempts to produce
human NT-ESCs have failed secondary to early embryonic arrest of SCNT e... 阅读全帖 |
|
j*********o 发帖数: 237 | 49 先多谢了!!
Tao Deng,Ph.D
Email: [email protected]
/* */
Research Fellow
National Cancer Institute
National Institutes of Health
Summary of Research Experience:
Deep understanding of epigenetic regulations, including DNA methylation,
histone modifications and chromatin dynamics
Rich experience on mouse embryonic stem cell manipulation
Full hands-on experience on Next-generation sequencing
Selected Publication:
1. Deng T*, Zhu ZI*, Zhang S, Postnikov Y, Huang D, Horrsch M, Furusawa T,
Beckers J,... 阅读全帖 |
|
p*****c 发帖数: 20445 | 50 Jun Lu PhD
Assistant Professor of Genetics
General Info
Bio
Research & Publications
Biographical Info
Education & Training
Ph.D.Boston University(2003)Postdoc AssociateBroad Institute or MIT and
Harvard, Cancer Program (2004 - 2008)
Research Summary
We are interested in using genomics to understand the role of non-coding
RNAs in mammalian development and disease. Currently, we are focusing on the
following topics. 1. Non-coding RNAs in blood stem cell differentiation and
malignancies 2. MicroRNA... 阅读全帖 |
|