m*p
发帖数: 226 | 1 lars2 is leucyl-tRNA synthetase 2, mitochondrial. 谁有这方面的背景？ 大量表
达或抑制表达会有什么样的反应？ 谢
谢！ |
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m*p
发帖数: 226 | 2 还有人说lars2 mutation correlates with type ii diabetes。
leucyl |
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f****y
发帖数: 104 | 3 Looks it is related to longevity in worm. See this paper:
A systematic RNAi screen identifies a critical role for mitochondria in C.
elegans longevity.
Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G.
Nat Genet. 2003 Jan;33(1):40-8. Epub 2002 Nov 25.
A classical genetic screen identified a mutation in the mitochondrial leucyl
-tRNA synthetase gene (lrs-2) that impaired mitochondrial function and was
associated with longer-lifespan. |
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f****y
发帖数: 104 | 5 没有这个线粒体就要麻烦大了，所以应该那里都有表达的。 |
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m*p
发帖数: 226 | 6 线粒体的tRNA synthesis is different from cytoplasm tRNA synthesis? 谁有这方
面的背景， 来扫盲。 谢谢！ |
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