G*******s
发帖数: 4956 | 1 首先给大家看个故事，然后再探讨经文：
林慈信牧师的《基督教教义发展史》中提到这个：
http://blog.sina.com.cn/s/blog_622134fd01013i7l.html
基督论的发展史(1)：基督论的争辩
HISTORY OF THE DOCTRINE OF CHRIST (1):
The Christological Controversies
(Louis Berkhof, A History of Christian Doctrines, pp. 101ff.)
基督论与三位一体之问题的关联
Connection of Christological and Trinitarian Problems
基督论的难题可以从一般神学（译注：神论）方面，与拯救论方面来加以
研究。早期教父对基督论拯救方面的关系，虽未曾加以轻忽，但他们在重要的讨论上却
没有重视。在三位一体争论的气氛中，他们从一般神学（译注：神论）方面来研究基督
，乃天经地义的事，而三位一体争论所导致的决定则是，基督为神的儿子，事与父同质
的，因此祂是神。从此而发生的问题，就是基督... 阅读全帖 |
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l****z
发帖数: 29846 | 2 By VAUHINI VARA
Stockton, Calif., will take the first step toward a possible bankruptcy
after the city council decided late Tuesday to launch a special mediation
with unions, creditors and others that cities in California must undergo
before pursuing a Chapter 9 filing.
While one council member opposed a resolution to pursue the mediation, also
known as a "neutral evaluation," six voted in favor of the move. The city
also passed resolutions to suspend certain debt payments and conduct an
investi... 阅读全帖 |
|
发帖数: 1 | 3
Download pdf published by SfN (Chapter from 'The History of Neuroscience in
Autobiography, Volume 8' edited by Larry R. Squire)
Yuh-Nung Jan's CV
Lily Jan's CV
Yuh-Nung Jan and Lily Jan
Birth
Family History and Growing Up
National Taiwan University
The Hiking Trip to Shitou in the Spring of 1967
Graduate School Application
Graduate Study at Caltech (1968锟974)
Seymour Benzer Lab (1974锟977)
Steve Kuffler锟絪 Lab at H... 阅读全帖 |
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i*******6
发帖数: 107 | 4 先说5楼的设计的不好的地方：
1.每个product中都必须维护一个消费者list，开销过大（想想amazon上几百万的东西
，每个东西对应一个product类...）
2.每个用户的责任里面有记录他自己的朋友们（也是用户），造成宏观的交互模式是多
对多，非常难以维护和复用。比如需求突然改为要分老用户和新用户，每种用户有特定
的行为。那么user代码必须改成：
olduser extends user{
list;
list;
}
newuser extends user{
list;
list;
}
如果再次扩展用户类型，问题会更严重。
3.user和product类紧耦合，造成的后果是如果需要改动user类（比如扩充新用户种类
），product类必须随之更改。 product类本身低内聚,它必须要负责本来不属于它的责
任：维护购买了它的用户，而且这种维护违背了一致性封装原则。
Mediator模式本身实现并不复杂，只需要有一个中介负责处理用户间交互即可，具有很
强的灵活性... 阅读全帖 |
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G*******s
发帖数: 4956 | 5 【 以下文字转载自 Church 俱乐部 】
发信人: Godwithus (神与我们同在), 信区: Church
标 题: 海德堡要理问答主日06
发信站: BBS 未名空间站 (Wed Apr 4 17:14:38 2012, 美东)
发信人: Godwithus (神与我们同在), 信区: BibleStudy
标 题: 海德堡要理问答主日06
发信站: BBS 未名空间站 (Wed Apr 4 17:12:42 2012, 美东)
海德堡要理问答主日06
来自CCWiki华人基督徒百科(Godwithus神同在网)
目录
1 英文版
2 英文2011版
3 赵中辉版
4 陈达/王志勇版
5 钱耀诚版（暂缺）
6 基督教要义圣经课程版
7 参考链接
英文版
6. Lord's day
Q. 16. Why must he be very man, and also perfectly righteous?
A.
Because the justice of God requires that the same human nature
which has sinned,... 阅读全帖 |
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z*t
发帖数: 863 | 6 Beutler得奖，Medzhitov会不会有意见？
http://www.sciencedirect.com/science/article/pii/S1074761309002
Ruslan Medzhitov
This year marks the 20th anniversary of a publication (Janeway, 1989) that
in many ways revolutionized our understanding of the immune system. As part
of the proceedings of the Cold Spring Harbor Symposium on Immune Recognition
, the paper authored by the late Charles A. Janeway, Jr. was not a standard
peer-reviewed publication. In fact, Charlie used to refer to it as “the
best paper I've ... 阅读全帖 |
|
G*******s
发帖数: 4956 | 7 海德堡要理问答主日06
来自CCWiki华人基督徒百科(Godwithus神同在网)
目录
1 英文版
2 英文2011版
3 赵中辉版
4 陈达/王志勇版
5 钱耀诚版（暂缺）
6 基督教要义圣经课程版
7 参考链接
英文版
6. Lord's day
Q. 16. Why must he be very man, and also perfectly righteous?
A.
Because the justice of God requires that the same human nature
which has sinned, should likewise make satisfaction for sin; (a)
and one, who is himself a sinner, cannot satisfy for others. (b)
(a) Ezek.18:4,20; Rom.5:12,15,18; 1 Cor.15:21; Heb.2:14-16; 1
Pet.3:18; Isa.53:3-5,10,11. (b) Heb.7:26,27; Ps.49:7... 阅读全帖 |
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a****r
发帖数: 12375 | 8 二本应届生在他司九年的收入情况，供大家参考 (转载)
http://bbs.c114.net/thread-862899-1-1.html
lxb365 1#发表于 2015-11-16 12:18:16 |只看该作者 |倒序浏览
年度 收入 增长率
2006 35000 0.00%
2007 50000 42.86%
2008 80000 60.00%
2009 110000 37.50%
2010 202946 84.50%
2011 317708 56.55%
2012 314784 -0.92%
2013 337654 7.27%
2014 622632 84.40%
这些数据都是每年报税单上的金额，包含了工资，股票分红和奖金，
以及所有发到个人账户上的部分，应该是很客观的。
现在华为每... 阅读全帖 |
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w********2
发帖数: 632 | 9 Cellular competency (natural transformation) refers to the active uptake of
free (extracellular) DNA across the cell wall and cell membrane(s) using
cellular machinery designed to facilitate the process (Dubnau, 1999; Lorenz
and Wackernagel, 1994). It is a highly regulated physio- logical state that
is often sensitive to environmental cues (Molin and Tolker-Nielsen, 2003).
When the DNA is her- itably incorporated into the recipient’s genome, the
pro- cess is known as transformation.
Bacterial co... 阅读全帖 |
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k*****e
发帖数: 22013 | 10 贴一下原文。
Bright Minds and Dark Attitudes
Lower Cognitive Ability Predicts Greater Prejudice Through Right-Wing
Ideology and Low Intergroup Contact
Gordon Hodson and
Michael A. Busseri
+ Author Affiliations
Brock University
Gordon Hodson, Department of Psychology, Brock University, 500 Glenridge Ave
., St. Catharines, Ontario, Canada L2S 3A1 E-mail: g*****[email protected]
Abstract
Despite their important implications for interpersonal behaviors and
relations, cognitive abilities have been largely ignore... 阅读全帖 |
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l****z
发帖数: 29846 | 11 UPS Pilots Seek Strike: Union says Salary of $238,000 Not Enough
With the holiday shopping season just about upon us, the Independent Pilots
Association (IPA), a trade union representing pilots at UPS, said its
leadership has called on its 2,528 members to authorize a pilot strike
against UPS.
Please consider Further Airline Problems are Brewing at UPS.
The possibility of a major disruption to UPS domestic and international
air cargo services has moved closer after the union representing pil... 阅读全帖 |
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G***a
发帖数: 27294 | 12 好的话，我就去听了, 这是Vice Chancellor invite的讲座。。。 suppose是good
research
Erin E. Kershaw, MD, assistant professor of medicine, School of Medicine
“Lipolysis in Metabolic Syndrome: Beyond Adipose Tissue.”
Topic Overview:
Obesity and metabolic syndrome are global health threats. Insulin resistance
and metabolic complications of obesity are strongly associated with
intracellular accumulation of triacylglycerol (TG); however, the mechanisms
underlying TG accumulation and its relationship to lipid-induced tox... 阅读全帖 |
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R******d
发帖数: 644 | 13 转的；打字太费事了。http://www.scripturecatholic.com/saints.html#saints-III
III. Specific Instructions to Mediate and Examples of Subordinate Mediation
New Testament
Matt. 5:44-45 - Jesus tells us to pray for (to mediate on behalf of) those
who persecute us. God instructs us to mediate.
Matt. 17:1-3; Mark 9:4; Luke 9:30-31 – deceased Moses and Elijah appear at
the Transfiguration to converse with Jesus in the presence of Peter, James
and John (these may be the two “witnesses” John refers to in Rev. 11:3). |
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Z****o
发帖数: 999 | 14 佛教中的mediation我可能确实不了解，这个我没有什么不好意思不去承认的。
那么可否请问”自认为已经理解了佛教中的mediation的JeanIris“(这个你应该同意吧
)，你可以不可以告诉我，在佛教的mediation中：
1) subject是什么？
2) object是什么？
3) 有没有subject对于object的干涉作用？
你也可以分几个阶段来谈，比如初始阶段怎样，到了什么果位以后又怎样，最后证得涅槃境
界后又是怎样。
但是总不能因为我不理解mediation，上述三个问题就没有答案吧？
books/informations in the
common senses or
science is we
mechanisms, but not all
further
some
setups or
time it happens
field. |
|
w***7
发帖数: 1637 | 15 source：http://bbs.netbig.com/thread-2491712-1-2.html
看了一下，今年不错啊，和清华并驾齐驱。
而且下半年我知道的还有两篇NS。
~~~~~~~~~~~~~~~~~
1.
Yuan W, Wu T, Fu H, Dai C, Wu H, Liu N, Li X, Xu M, Zhang Z, Niu T, Han Z,
Chai J, Zhou XJ, Gao S, Zhu B
Dense Chromatin Activates Polycomb Repressive Complex 2 to Regulate H3
Lysine 27 Methylation
Science, DOI: 10.1126/science.1225237, Aug. 24, 2012
2.
Liu B, Du H, Rutkowski R, Gartner A, Wang X
LAAT-1 Is the Lysosomal Lysine/Arginine Transporter That Maintains Amino
Acid Homeostasis
S... 阅读全帖 |
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K*******6
发帖数: 8 | 16 一直不同意离婚，三年后的一天，我无路可走，我泣不成声的同意和他离婚。7月份的
纽约，我却不得不穿上冬衣，因为我很冷。
结婚五年了，女儿3岁，孩子牵扯了我三年。本以为我可以用心把他找回来，结果是他
越走越远，最后我找不到他了，也找不到自己了。三年的让步足以让一个人失去自我。
我们在办离婚。但是现在我很困惑，需要各位指点迷津。
我同意离婚后，很多人推荐Mediation。结果去了两次，毫无进展。Mediation既没有道
德束缚，也没有法律约束，Mediator也不会维护任何一方的权利，所以他的要求很过分
。我最主要想和各位讨论关于孩子的事情。以下是他的要求：
1，孩子要一半的监护权。
2，不给我孩子的抚养费。
3，一周3天他来照顾，其中一天必须是周日（因为他要带孩子去教堂），一年中他宗教
节日女儿归他，大概16天左右，美国节假日一半孩子归他。
现在的情况是：
1，他刚刚失去工作，因为工作表现不好被辞掉。
2，我年薪8万多一些，他失去工作前7.5万
3，今年三月，他动手推我，我头撞墙后摔在地上，我报警。之后法官给我一年的order
of protection。但是我百般努力配合他的律师帮他... 阅读全帖 |
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f******d
发帖数: 2394 | 17 心虚了？不是告诉你了么中崩元年是2013年。看中国经济就看房价。2013年是顶点。现
在是缓坡下降（听说过股市里的尖底圆顶么？）。一旦加速下降，就是主跌浪开始了，
学名叫中国金融危机。当然这会是美国的叫法，中国会把它叫做第二次金融危机（暗示
是美国引起的）。你可以很快验证看看这名词。如果你真好学的话，下面给你贴一篇教
学文章。其中的几个名人，Bill Gross，是太平洋基金的创始人之一，也是中投2011年
雇的朱长虹的老板的老板。George Soros，大名鼎鼎，就不多说了。Michael Diekmann
，世界最大的保险公司的老板。这篇文章里有很多信息，都和现在的金融市场和即将发
生的金融危机相关。
Fall of the Bond King: How Gross Lost Empire as Pimco Cracked
By Mary Childs - Dec 3, 2014
Bill Gross, the 70-year-old king of bonds, rushed through the offices of his
$2 trillion empire on a ... 阅读全帖 |
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l****p
发帖数: 27354 | 18 http://foreignpolicy.com/2013/05/30/the-bomb-didnt-beat-japan-s
The Bomb Didn’t Beat Japan… Stalin Did
BY WARD WILSON MAY 30, 2013
U.S. use of nuclear weapons against Japan during World War II has long been
a subject of emotional debate. Initially, few questioned President Truman’
s decision to drop two atomic bombs, on Hiroshima and Nagasaki. But, in 1965
, historian Gar Alperovitz argued that, although the bombs did force an
immediate end to the war, Japan’s leaders had wanted to sur... 阅读全帖 |
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f******o
发帖数: 2469 | 19 Is legal advice via AI a good idea?
By Kayla MatthewsPublished 1 day ago
No CommentsShare
Artificial intelligence is a controversial subject in any field -- including
practicing the law. Even now, lawyers and law firms weigh the positives and
negatives of using AI to dispense legal advice or automate basic tasks.
Here’s a look at both sides of the argument.
How AI Might Be Beneficial in Law
Are there any instances where AI could be beneficial in law practices? There
may be 114,000 instances if p... 阅读全帖 |
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发帖数: 1 | 20 More leaked e-mails from Hillary Clinton’s time as Secretary of State prove
that she was taking foreign policy advice from left-wing billionaire
activist George Soros.
An e-mail provided by WikiLeaks showed Soros reaching out to Secretary
Clinton over a foreign policy dispute in Albania.
“Dear Hillary,
“A serious situation has arisen in Albania which needs urgent attention at
senior levels of the US government. You may know that an opposition
demonstration in Tirana on Friday resulted in the dea... 阅读全帖 |
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A**u
发帖数: 2458 | 21 大牛
能不详细解释一下3的mediator pattern,
我专门学习了一下mediator,
请问这里，用什么做mediator呢 |
|
A**u
发帖数: 2458 | 22 大牛，
我又仔细看了看你的mediator 设计，有点不对啊
你的mediator只指向一个user?
难道mediator 不应该像个中转站，被多个user共享吗? |
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i*******6
发帖数: 107 | 23 那我写个client你就懂了：
class client{
public static void main(String args){
mediator m = new mediator;
//假设有3个用户：amazon, google, facebook， 相互为好友， amazon买过
book，facebook买过kindle
user google = new user(m);
user amazon = new user(m);
user facebook = new user(m);
product book = new product();
product kindle = new product();
google.open(book); //amazon will be showed
// 现在google打开新的一页了！
google.open(kindle); //amazon will not ... 阅读全帖 |
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s******e
发帖数: 493 | 24 Mvc should be good. But using controller as the mediator might create a god
class that knows too much. You should try to cut coupling by introducing
events
. Only Using mediator pAttern to capture simple interactions.
For example, view should implement EventDispatcher; controller should allow
user to register event types to commands mapping at high level...
In other words, making your mvc event driven rather than based on mediator
pattern. |
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c****s
发帖数: 66 | 25 有兴趣的站内联系
Title: Engineer
Location: San Ramon, CA
Duration: 12 Months
Project Name:
UMTS/LTE Data Mediation
Project Description:
· This project is developing UMTS and LTE data mediation platforms
that will provide data to drive multiple downstream applications.
· The supported application areas include performance monitoring,
troubleshooting, self organizing network (SON), RAN optimization, and
location-based services.
Job Description:
· Assist with the development of UMTS... 阅读全帖 |
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b********s
发帖数: 9 | 26 Postdoctoral and Technician Positions in the Dinshaw J. Patel lab
in the Department of Biology, SUSTC, Shenzhen.
Dinshaw J. Patel is a member of the United States National Academy of
Sciences. The Patel structural biology lab is set to open on March 1, 2016
in the Department of Biology at the South University of Science and
Technology of China (SUSTC) in Shenzhen. SUSTC, located in picturesque and
environmentally healthy Shenzhen, is a new University that aims to become a
world-leader in Science... 阅读全帖 |
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w**********g
发帖数: 48 | 27 多谢你。
我没有拖过，每个月还清，然后又欠。
我查了些信息，贴这里，很长，有兴趣的人可以看看，基本确定这个就是骗子，还好他
问我SSN的时候我就什么都没有说了，不然估计就惨了
希望如果类似情况，大家能直接忽略那些垃圾邮件（那些邮件看着挺吓人和诱人）
Credit Resolution Advisors Just Sent Me a Mailer. – Sumir
CRAisevil
The owners of CRA or CreditResolution Advisors should be arrested for
fraud and deceit.
I’m contacting the FBI.
The more people who contact the FBI, the quicker these guys will be on
the lam.
Jblittle40
Must be a scam. I received pink notices from them trying to renegotiate
A cr... 阅读全帖 |
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c****8
发帖数: 33 | 28 怎么能当上海科大的副校长？
EDUCATION:
1990 Ph.D. Inorganic Chemistry, Purdue University
1982 Undergraduate Education, East China Normal University, Shanghai,
China.
EXPERIENCE:
1998- Professor of Chemistry, Southeast Missouri State University
1994- Associate Professor of Chemistry, Southeast Missouri State University
1990-1994 Assistant Professor of Chemistry, Southeast Missouri State
University
1993 summer NASA JOVE Research fellow, Lewis Research Center, Cleveland, OH.
1991 summer Visiting Professor,... 阅读全帖 |
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L******r
发帖数: 141 | 29 All the materials were taken from Administrative Decisions (Aliens with Extraordinary Ability/ Outstanding Professors and Researchers). 所以这些话是权威!!!
I downloaded All the AAO decisions for the past three years. I read one by one for a total number of more than 200 decisions. I took good paragraphs from recommendation letters which IOs thought have met criterion of contribution. Because the works were from PDF files, I had to reformat them into word file.
It took me many hours to do the work and I... 阅读全帖 |
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i********n
发帖数: 171 | 30 1.Anti-diabetic and anti-obesitic effects of aqueous extracts of
Yangkyuksanhwa-tang and its two major compositions on db/db mice
2.13-Methyltetradecanoic acid induces bladder cancer cell autophagy via ROS-
mediated PI3K/AKT and MAPK pathways
3.Ticagrelor inhibits oxLDL-induced migration of dendritic cells via miR-145
-5p mediated HSPA14 downregulation resulting in repressed atherogenesis
4.Co-delivery of IL17RB siRNA and doxorubicin by chitosan-based
nanoparticles for enhanced anticancer effica... 阅读全帖 |
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i********n
发帖数: 171 | 31 请发简历及你想审稿的文章编号，可以多选。
到[email protected]/* */
1. Combination of 2-deoxy D-glucose and metformin for synergistic
inhibition of non-small cell lung cancer: A reactive oxygen species and P-
p38 mediated mechanism
2. MYC gene regulating the occurrence and metastasis of prostate cancer
by STAT signaling pathways
3. Ursolic Acid Mediates Hepatic Protection through enhancing of anti-
aging biomarkers.
4. New insight on using aged garlic extract against toxic impacts of
titanium dioxide... 阅读全帖 |
|
T*******i
发帖数: 805 | 32 在美国上小额法庭确实像上菜市场，不用请律师。上网搜一下magistrate court+your
county name，关于驱赶租客、追讨房租，magistrate court有完整的instruction, 你
照作就是。麻烦的地方是court多数在down town，请假难，开车远，趴车贵，上庭烦。
到庭后你就会发现跟菜市场差不多，就当法官和警察是grocery store里的售货员与保
安好了，他们也是在那做生意，区别是法官有锤子，警察有棒棒。然后坐的等点名，小
心不要错过，那些黑妹黑嫂们不大会念我们中国人名字。然后法庭会offer你mediation
service. Google一下Magistrate Court Mediation unpaid rent dispute。如果你有
确凿证据，不要mediation，因为那只是给租客拖延时间。尽快拿到法庭的eviction
order。不过呀，也没啥用，人家说没钱，银行账户里也不放钱，可以扣工资，但工作
单位你找不到。没办法的办法是，把债权卖给unpaid rent collection agent。
我的惨痛教训是，美国... 阅读全帖 |
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b********1
发帖数: 1299 | 33 如果是有loan contingency, 一般很少有seller会拖延deposit release. 这是自找麻
烦. 可能还是对方agent觉得您这边有问题. 而且您也需要自己的agent的帮助.
您这边的agent要送form给对方要求release deposit.
如果seller无理拖延, 您首先要做mediation, then arbitration,然后才是找律师打官
司. 千万不要一开始就找律师.
您可以参考mediation proces
http://www.car.org/mediation/consumers/begin/
Good luck.
押金 |
|
R******d
发帖数: 644 | 34 不是神需要mediator，是他赐给我们一位mediator，而这位mediator既完全是神又完全
是人。 |
|
C****i
发帖数: 1776 | 35 CHAPTER XXI
Of Religious Worship, and the Sabbath Day
I. The light of nature showeth that there is a God, who hath lordship and so
vereignty over all, is good, and doth good unto all, and is therefore to be
feared, loved, praised, called upon, trusted in, and served, with all the he
art, and with all the soul, and with all the might.[404] But the acceptable
way of worshiping the true God is instituted by himself, and so limited by h
is own revealed will, that he may not be worshiped according to... 阅读全帖 |
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J*******g
发帖数: 8775 | 36 我认为神确实不变，但是人是受时空约束的。上帝跟人作用时人看神似乎是变的，其实
是人的视角问题。
保罗说明了为什么要有旧约律法。
19 Why, then, was the law given at all? It was added because of
transgressions until the Seed to whom the promise referred had come. The law
was given through angels and entrusted to a mediator. 20 A mediator,
however, implies more than one party; but God is one.
24 So then, the law was our guardian until Christ came, in order that we
might be justified by faith.
旧约律法不是废除了，而是耶稣遵守了律法，然后让信和爱代替了旧约律法，基督徒通
过对耶稣的信仰和爱而遵守了律法，
Romans 10(ESV)... 阅读全帖 |
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J*******g
发帖数: 8775 | 37 你还是先把三位一体搞清楚在来反吧。
保罗说明了为什么要有旧约律法。
19 Why, then, was the law given at all? It was added because of
transgressions until the Seed to whom the promise referred had come. The law
was given through angels and entrusted to a mediator. 20 A mediator,
however, implies more than one party; but God is one.
24 So then, the law was our guardian until Christ came, in order that we
might be justified by faith.
旧约律法不是废除了，而是耶稣遵守了律法，然后让信和爱代替了旧约律法，基督徒通
过对耶稣的信仰和爱而遵守了律法，
Romans 10(ESV)
4 For Christ is the end of th... 阅读全帖 |
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Z****o
发帖数: 999 | 38 在诸多版友的一再提醒下，我非常坦率地承认自己对于佛教中的mediation并不了解，
于是就有了下面的问题：
那么可否请问已经理解了佛教中的mediation或者已经有部分修行体验的的版友(们）告
诉我，在佛教的修行实证(mediation)中：
1) 有没有subject？有的话，是什么？没有的话，为什么？
2) 有没有object？有的话，是什么？没有的话，为什么？
3) 有没有subject对于object的干涉作用？
可以分几个阶段来谈，比如初始阶段怎样，到了什么果位以后又怎样，最后证得涅槃境
界后又是怎样。
其实我对第三个问题最感兴趣，因为最近大家总是在讨论科学研究中的”干涉“效应，
搞得好像科学研究就因为这个”干涉“效应无法进行下去，穷途末路一般没有前途。
岂不知科研中的干涉效应只不过只是在量子效应这一块，反而是宗教的修行打坐观禅等
行为中有这大量的干涉效应和反馈效应，但在本版诸版友中似乎没有什么人意识到,真是
让人有一百步笑十步的感觉。悲愤一下可以吧！:) |
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f*********e
发帖数: 24 | 39 Relation between MeCP2 and Rett syndrome
1999-10 Nat Gen Huda Y. Zoghbi Rett syndrome is caused by mutations
in X-linked MECP2, encoding methyl-CpG-binding protein 2
Mouse models: whole-body knockout, brain-specific, brain-region-specific,
knock-in,..., over-expression, rescue, ...
2001-03 Nat Gen Adrian Bird A mouse Mecp2-null mutation causes
neurological symptoms that mimic Rett syndrome
2001-03 Nat Gen Rudolf Jaenisch Deficiency of methyl-CpG bindi... 阅读全帖 |
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k*****n
发帖数: 417 | 40 Their top5 highly cited research papers:
Wei Gu:
Title: Negative control of p53 by Sir2 alpha promotes cell survival under
stress
Times Cited: 822 (from Web of Science)
Title: Deacetylation of p53 modulates its effect on cell growth and
apoptosis
Times Cited: 331 (from Web of Science)
Title: Deubiquitination of p53 by HAUSP is an important pathway for p53
stabilization
Times Cited: 319 (from Web of Science)
Title: Mono-versus polyubiquitination: Differential control of p53 fate by
Mdm2
Times Ci... 阅读全帖 |
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B*****e
发帖数: 1005 | 41 140后的几个也不是美国AP啊，文章比跟前几个有距离
140 黄亿华 男 1971年10月 中国科学院生物物理研究所 生命
科学 2004年02月毕业于[美国]康奈尔大学 [美国]休斯医学研究所/西南医学中
心 讲师
1: Huang Y, Smith BS, Chen LX, Baxter RH, Deisenhofer J. Insights into pilus
assembly and secretion from the structure and functional characterization of
usher PapC. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7403-7. Epub 2009
Apr
20. PubMed PMID: 19380723; PubMed Central PMCID: PMC2670885.
2: Lin SC, Huang Y, Lo YC, Lu M, Wu H. Crystal structure of the BIR1 doma... 阅读全帖 |
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m********a
发帖数: 239 | 42 Read it here: http://the-scientist.com/2011/08/31/puncturing-the-myth/
Puncturing the Myth
Purinergic signaling, not mystical energy, may explain how acupuncture works.
By Geoffrey Burnstock | August 31, 2011
4 Comments
According to traditional Chinese medical theory, acupuncture points are
situated on meridians along which qi, the vital energy, flows. However, I
have proposed a less mysterious neurophysiological mechanism to explain the
beneficial effects of this 2,000-year-old practice (Medica... 阅读全帖 |
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l**********1
发帖数: 5204 | 43 Johns Hopkins too 连tenure都过不了
不是看已有领域的挖掘 还要看新领域的digged out data and results.
please refer:
for example:
Lee Martin, Ph.D.
Professor of Pathology, Neuroscience
//pathology.jhu.edu/department/divisions/neuropathology/faculty-staff.cfm
his group recent paper:
线粒体上的控制 NO 的通道控制着细胞老化和自然死亡的过程
"The mitochondrial permeability transition pore regulates nitric oxide-
mediated apoptosis of neurons induced by target deprivation.” (2011)
J Neurosci. 31: 359-370.
PubMed link:
//www.ncbi.nlm.nih.gov/pubmed/2... 阅读全帖 |
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S**********e
发帖数: 1789 | 44 Tony Hunter的博后，独立以后表现很不错。
Yang W, Xia Y, Hawke D, Li X, Liang J, Aldape K, Hunter T, Yung WK, and Lu Z
. PKM2 phosphorylates histone H3 and promotes gene transcription and
tumorigenesis. Cell 150(4):685-696,
Ji H, Ding Z, Hawake D, Jiang B, Mills G, Lu Z. AKT-dependent
Phosphorylation of Niban Regulates Nucleophosmin- and MDM2-Mediated p53
Stability and Cell Apoptosis. EMBO Reports 13(6):554-60,
Yang W, Xia X, Zheng Y, Liang J, Huang W, Gao X, Aldape K, Lu Z. Nuclear
PKM2 regulates beta-catenin ... 阅读全帖 |
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p**t
发帖数: 160 | 45 and this
IMMUNOBIOLOGY AND PATHOGENESIS OF VIRAL HEPATITIS
Annual Review of Pathology: Mechanisms of Disease
Vol. 1: 23-61 (Volume publication date February 2006)
DOI: 10.1146/annurev.pathol.1.110304.100230
Luca G. Guidotti1,2 and Francis V. Chisari1
1Department of Molecular and Experimental Medicine, Scripps Research
Institute, La Jolla, California 92037; email: g******[email protected], fchisari
@scripps.edu
2Immunopathogenesis of Liver Infections Unit, San Raffaele Scientific
Institute, Milan 201... 阅读全帖 |
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p**t
发帖数: 160 | 46 and this
IMMUNOBIOLOGY AND PATHOGENESIS OF VIRAL HEPATITIS
Annual Review of Pathology: Mechanisms of Disease
Vol. 1: 23-61 (Volume publication date February 2006)
DOI: 10.1146/annurev.pathol.1.110304.100230
Luca G. Guidotti1,2 and Francis V. Chisari1
1Department of Molecular and Experimental Medicine, Scripps Research
Institute, La Jolla, California 92037; email: g******[email protected], fchisari
@scripps.edu
2Immunopathogenesis of Liver Infections Unit, San Raffaele Scientific
Institute, Milan 201... 阅读全帖 |
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h******y
发帖数: 351 | 47 Jaenisch lab最新发表的利用CRISPR同时敲除5个基因的文章。CRISPR前途无限啊。再搞
出几个inducible的CRISPR就更厉害了。
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/C
as-Mediated Genome Engineering
http://www.ncbi.nlm.nih.gov/pubmed/23643243
Cell. 2013 May 1. pii: S0092-8674(13)00467-4. doi: 10.1016/j.cell.2013.04.02
5.
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/C
as-Mediated Genome Engineering.
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R.
Source
W... 阅读全帖 |
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l********n
发帖数: 260 | 48 揭露臧敬五在新闻媒体上的谎言——兼评其JCI论文
作者：胆大妄为
方舟子先生，
你好！本人注意到臧敬五在很多新闻媒体上对其作为通讯作者发表在JCI上
的论文加以宣传后，翻阅了这篇论文（1），发现臧敬五胆大妄为，编造谎言，
欺骗中国新闻媒体，应予以揭露。
先看二篇臧敬五在媒体上的宣传：
“骨桥蛋白”是引发类风湿性关节炎的顽凶
新华网上海３月２日电（胡德荣、仇逸）严重影响人类健康和生活质量的类
风湿性关节炎（注：rheumatoid arthritis，RA）研究获得重大突破性进展。我
国科研人员在国际上第一次阐明了骨桥蛋白（注：osteopontin ，OPN）在类风
湿性关节炎发病中的作用，发现“骨桥蛋白”是引发类风湿性关节炎的顽凶，为
治疗类风湿性关节炎找到了临床手段和药物靶点。……
http://www.stcsm.gov.cn/news/detail.asp?pid=64857
我专家突破类风湿关节炎治疗世界难题
上海分院
日前，中国科学院上海生命科学研究院健康科学中心主任臧敬五教授，带领
科研人员完成了“骨桥蛋白在类风湿性关节炎中的病理机制”研究，其论文已刊
登在3月2日出版的... 阅读全帖 |
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