h******b
发帖数: 312 | 1 Science. 2003 May 16;300(5622):1152-5.
Distinct cohesin complexes organize meiotic chromosome domains.
Kitajima TS, Yokobayashi S, Yamamoto M, Watanabe Y.
Department of Biophysics and Biochemistry, Graduate School of Science,
University of Tokyo, Tokyo 113-0033, Japan.
Meiotic cohesin complexes at centromeres behave differently from those along
chromosome arms, but the basis for these differences has remained elusive. The
fission yeast cohesin molecule Rec8 largely replaces its mitotic counterpa |
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A******r
发帖数: 974 | 2 1.
Mol Gen Genet. 1988 Dec;215(1):10-8.
The detection of mitotic and meiotic aneuploidy in yeast using a gene dosage
selection system.
Whittaker SG, Rockmill BM, Blechl AE, Maloney DH, Resnick MA, Fogel S.
Link:
http://www.springerlink.com/content/l30231v828l8w7q4/fulltext.p
2.
Mutation Research/Genetic Toxicology
Volume 242, Issue 3, November 1990, Pages 231-258
The detection of mitotic and meiotic chromosome gain in the yeast
Saccharomyces cerevisiae: Effects of methyl benzimidazol-2-yl carbam... 阅读全帖 |
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A********e
发帖数: 354 | 3 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
p*******g
发帖数: 2976 | 4 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
O***n
发帖数: 13127 | 5 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
m***f
发帖数: 1622 | 6
扯淡呢，看看高最近两年发表的文章吧
CELL STEM CELL, JBC, STEM CELL, PNAS，都是很不错的
就这样还不能PROMOTION? 在美国都可以tennure了
1. Wu T., Wang H., He J., Kang L., Jiang Y., Liu J., Zhang Y., Kou
Z., Liu L., Zhang X., Gao S. (2011) Reprogramming of trophoblast stem
cells into pluripotent stem cells by Oct4. Stem Cells 2011 Feb 8.
[Epub ahead of print].
2. Kang L., Wu T., Tao Y., Yuan Y., He J., Zhang Y., Luo T., Kou Z.,
Gao S. (2010) Viable mice produced from 3-factor induced pluripotent
stem (iPS) cells through tetrapl... 阅读全帖 |
|
i****n
发帖数: 56 | 7 Genome. 2011 Jan;54(1):26-32.
Karyotype of Zea luxurians and Z. mays subsp. mays using FISH/DAPI, and
analysis of meiotic behavior of
hybrids.
González GE, Poggio L.
Pubmed link:
http://www.ncbi.nlm.nih.gov/pubmed/?
term=Karyotype+of+Zea+luxurians+and+Z.+mays+subsp.+mays+using+FISH%2FDAPI,+
and+analysis+of+m
eiotic+behavior+of+hybrids
Please send paper to h****[email protected]
Thank you very much!!! |
|
a********k
发帖数: 2273 | 8 花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
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l**********1
发帖数: 5204 | 9 Sure
plus
one review
Queitsch C et al. (2012)
Lessons from model organisms: phenotypic robustness and missing heritability
in complex disease.
PLoS Genet. 8: e1003041.
HTTP: //www.ncbi.nlm.nih.gov/pubmed/23166511
and one HSP90 Hidden Markov chain models simulation
its title:
The evolutionary history of meiotic genes: early origins by duplication and
subsequent losses
by Pightling AW
2011 University of Iowa PhD dissertation
HTTP: //ir.uiowa.edu/etd/2960/ |
|
i****g
发帖数: 3896 | 10 又是一连两篇Science文章：
http://m.sciencemag.org/content/338/6114/1622
Science 21 December 2012:
Vol. 338 no. 6114 pp. 1622-1626
DOI: 10.1126/science.1229164
Report
Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a
Single Human Cell
Authors
Chenghang Zong1,*,
Sijia Lu1,*,†,
Alec R. Chapman1,2,*,
X. Sunney Xie1,‡
1Department of Chemistry and Chemical Biology, Harvard University, Cambridge
, MA 02138, USA.
2Program in Biophysics, Harvard University, Cambridge, MA 02138... 阅读全帖 |
|
l**********1
发帖数: 5204 | 11 Omg! FAQ her/is credit might be stolen !
if below Science paper last corres author Dawson DS read FAQ her/is
manuscript before Lol
pls refer Sci magazine advanced online release,
'Mps1 and Ipl1/Aurora B Act Sequentially to Correctly Orient Chromosomes on
the Meiotic Spindle of Budding Yeast.'
by
Meyer RE et al. and Dean S. Dawson
HTTP: //www.sciencemag.org/content/early/recent bla bla bla
31 January 2013 Science.1232518 |
|
b*****g
发帖数: 119 | 12 谢谢~ 你们都好热心
是这样的, 老鼠在出生后不久绝大多数的primary oocyte就开始生长了, 然后我只是在
25天左右的时候给激素, 2天后提取oocyte. 给激素的目的其实就是更进一步促进
follicle and oocyte growth 等到我提取的时候他们就是已经很成熟的meiotically
competent的卵子了 所以我认为跟我打针后2天就取卵关系不大. zp3 应该出生后不久
就开始表达了 倒是越到后来表达变多倒是很有可能.
那些静息的形态很明显, 这种的卵子和follicle之间还没有形成antrum 所以我是不会
用的.
然后哺乳动物的oogenesis比较奇特 不是contineous process, arrest at prophase I
. 所以在我分离oocyte的时候他们还是在2倍体. 按理说如果cre 有效果的话就已经把2
个都切了
我想法子做个oocyte' genotype或者RT把, 如果不work的话我打算一个allele的敲 做
老鼠genetics 真是费时间阿 T-T |
|
b*****g
发帖数: 119 | 13 我比较惊讶的是在14天follicle就会respond to PMSG嘛? 可不可以丢一个reference
给我呀 当然这些分离出来的oocyte应该不具备meiotic competence 对吧? |
|
m******g
发帖数: 467 | 14 最近打算新开一个项目，正在集中阅读那方面文献，哈哈。
所以感觉很少看这些general的paper.
Science 14.07.18
推荐：
1. (recommended Elife paper) Genome rearrangements and pervasive meiotic
drive cause hybrid infertility in fission yeast
稍微了解一下：
1. Human tRNA synthetase catalytic nulls with diverse functions
2. Putting the genetic breaks on breeding
小知识：
1. How the worm changes its tastes
Synaptic PI3K is crucial for the behavioral switch caused by learning
2. Organogenesis in a dish: Modeling development and disease using organoid
techno... 阅读全帖 |
|
t********n
发帖数: 64 | 15 Genome Analyses of Single Human Oocytes
Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a
Single Human Cell
Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-
Genome Sequencing
Rare event of histone demethylation can initiate singular gene expression of
olfactory receptors
这是为了欢度圣诞么。。太霸道了 |
|
m******g
发帖数: 467 | 16 PNAS 14.09.16
稍微了解一下：
1. Single cell sequencing reveals low levels of aneuploidy across mammalian
tissues
Disagrees with previous FISH and SKY results showing high aneuploidy
小知识：
1. Combined fluorescent and electron microscopic imaging unveils the
specific properties of two classes of meiotic crossovers |
|
m******g
发帖数: 467 | 17 PNAS 14.09.16
稍微了解一下：
1. Single cell sequencing reveals low levels of aneuploidy across mammalian
tissues
Disagrees with previous FISH and SKY results showing high aneuploidy
小知识：
1. Combined fluorescent and electron microscopic imaging unveils the
specific properties of two classes of meiotic crossovers |
|
m****e
发帖数: 489 | 18 N Engl J Med. 2016 Jan 21;374(3):223-232.
Mutations in TUBB8 and Human Oocyte Meiotic Arrest.
Feng R1, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A,
Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, Qu R, Wang X, Sun Z, Liu M, Shi H
, Wang H, Feng Y, Shao R, Chai R, Li Q, Xing Q, Zhang R, Nogales E, Jin L,
He L, Gupta ML Jr, Cowan NJ, Wang L.
Please send to [email protected]
/* */ Thanks! |
|
m****e
发帖数: 489 | 19 N Engl J Med. 2016 Jan 21;374(3):223-232.
Mutations in TUBB8 and Human Oocyte Meiotic Arrest.
Feng R1, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A,
Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, Qu R, Wang X, Sun Z, Liu M, Shi H
, Wang H, Feng Y, Shao R, Chai R, Li Q, Xing Q, Zhang R, Nogales E, Jin L,
He L, Gupta ML Jr, Cowan NJ, Wang L.
Please send to [email protected]
/* */ Thanks! |
|
p*******g
发帖数: 2976 | 20 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
