D*a
发帖数: 6830 | 1 Nature忘了它有一整本杂志都是这玩意儿了？
两年前Science发了一篇GWAS方法研究人类长寿相关基因分析的文章，一年后被说有技
术问题，假阳性，撤稿了，最近刚从Plos One发出来了。两年前就瞅了一眼结果，现在
看貌似大结论没变啊？还没细看，细看也看不懂。。。
http://www.nature.com/nature/journal/v487/n7408/full/487427a.ht
Scientists and journals must work together to ensure that eye-catching
artefacts are not trumpeted as genomic insights, says Daniel MacArthur.
When a study of the genomes of centenarians reported genetic variants
strongly associated with exceptional longevity1, it received widespread
media and publi... 阅读全帖 |
|
v********a
发帖数: 646 | 2 1) Research Scientist, Antibody Purification (Biochemistry / Antibody)
2) Research Scientist, Reagent Printing (Biochemistry / Printer)
3) Research Scientist, Assay Development (Biochemistry / Red Blood Cell)
1) 15099 - Research Scientist, Antibody Purification (Biochemistry /
Antibody)
Norcross, GA, US
Employment Type: Full-Time
This position is not eligible for sponsorship for work authorization by
Immucor, Inc. Therefore, if you will require sponsorship from us for work
author... 阅读全帖 |
|
o*********y
发帖数: 65 | 3 Suppose we have a function F(X) that we can evaluate. X is a vector, and
suppose F() is convex. In this case, what is the best strategy (minimal steps
to find minimal) to find the minimal?
My current naive idea needs 2^n+n+1 times evaluation each step (n is the
dimention of X). I guess this should be a classic problem, I wonder what's
the best strategies known? thanks a lot, bow. |
|
l*****e
发帖数: 238 | 4 by minimizer, u mean minimum, right?
think of y=x(x-1)(x+1)
it has a unique local minimum between 0 and 1, but it's not a global minimum
have one local minimizer it must be the global minimizer. |
|
m******t
发帖数: 273 | 5 【 以下文字转载自 Statistics 讨论区 】
发信人: myregmit (myregmit), 信区: Statistics
标 题: Predict values of vectors by other vectors generated by black box
functions
发信站: BBS 未名空间站 (Sun Mar 2 11:38:56 2014, 美东)
Hi,
I need to solve a problem about predicting values of some numerical vectors
by using other numerical vectors with all these vectors in the same vector
set, which is generated by one or more black box functions.
Given a vector space:
P =[S_1, S_2, …, S_T | Sk is a vector of q numbers, k = 1, ..., T]... 阅读全帖 |
|
f*******g
发帖数: 55 | 6 Consider a dynamic process { Q[t] } evolving on the set of M-by-M positive
semi-definite matrices. In particular, { Q[t] } follows the recursive
equation:
Q[t+1] = Q[t] - Q[t] a[t] a[t]' Q[t] / (a[t]' (c I + Q[t] ) a[t]) + d I
where:
a[t] is an M-by-1 vector, which can be adjusted;
c and d are fixed positive real numbers; and
I is an M-by-M identity matrix.
Note that by normalization, we can consider a[t] to be a unit vector without
loss of generality.
The "total reduction" at time t
... 阅读全帖 |
|
x********i
发帖数: 905 | 7 http://iccm.mcm.ac.cn/dct/page/1
Invited Lectures
Group 1
Fan Qin: Cluster algebras and monoidal categorification
Fang Li: Positivity of acyclic sign-skew-symmetric cluster algebras via
unfolding method and some related topics
Cheng-Chiang Tsai: An attempt for affine Springer theory
Li Cai: The Gross-Zagier formula: arithmetic applications
Ming-Hsuan Kang: Geometric zeta functions on reductive groups over non-
archimedean local fields
Huanchen Bao: Canonical bases arising... 阅读全帖 |
|
m****p
发帖数: 404 | 8 原文
http://forums.studentdoctor.net/showthread.php?t=884279
念药学院的学长学姐有什么评论么
德州 加州 pharmacy school 一家一家的开 2015-2020 铁定会过饱和了吧
最后几段是讲his family 自己开店30年的经验/挫折
还有文中提到的 MTM 是什么缩写?
1st -- Before you jump on me, understand this: I am only speaking about what
I know from extensive analysis of the California market (maybe some of this
will translate into other states but again this is for California people
primarily). If you attend, UCSF, USC, Western, UCSD, etc this job market
post is for you.
2nd -- Feel... 阅读全帖 |
|
s********4
发帖数: 64 | 9 CC: Axillofemoral bypass surgery for an occluded right limb
HPI: 62 yo male with antiphospholipid syndrome presents to VAMC for
scheduled axillofemoral bypass surgery on 10/22. Patient was instructed to
hold warfarin and start enoxaparin for bridging prior to surgery. Patient
was admitted pre-op on 10/21 and switched to a heparin drip for
anticoagulation. Surgery was completed successfully with no complications
on 10/22. Post operatively patient feels much better with minimal pain in
his fo... 阅读全帖 |
|
x*******n
发帖数: 185 | 10 Kohn-Sham equations
There are two schools of thought on how to achieve the minimization of the
total energy. The more prevalent approach in the physics community is to
view the calculation directly as a problem in numerical minimization and to
apply modern techniques for constrained numerical minimization. We shall
return to this approach in the second half of the this course. The second
school of thought, more prevalent in the chemistry community, is to derive
the Lagrange-multiplier equations |
|
i*****r
发帖数: 1302 | 11 现在有个数列,我要这个数列里的每个数都相同,应该minimize什么?
我想到的方法是min(standard deviation),如果都相同,那么stdev肯定是0. 但有时候
结果会出现1个极端值,其他数都相同
但事实上我可以接受不全部相同,只要接近就OK, 举个例子
[1,1,4] 也好过 [3,3,0]
补充:
我的意思是,我想要output(数列)里的每个数都想同,但在一些限制条件下是没办法达成的,如果按照我的方法,minimize他们的stdev,那么有可能会得到这么个结果
[3,3,3,3,3,3,3,3,3,0]
但是我不想有那个0出现,我宁可大家都接近一些,比如
[4,1,1,1,2,4,1,1,2,3]
例子可能不准确,但就是这么个意思,所以我想是不是有别的可以minimize? |
|
m******t
发帖数: 273 | 12 【 以下文字转载自 Statistics 讨论区 】
发信人: myregmit (myregmit), 信区: Statistics
标 题: Predict values of vectors by other vectors generated by black box
functions
发信站: BBS 未名空间站 (Sun Mar 2 11:38:56 2014, 美东)
Hi,
I need to solve a problem about predicting values of some numerical vectors
by using other numerical vectors with all these vectors in the same vector
set, which is generated by one or more black box functions.
Given a vector space:
P =[S_1, S_2, …, S_T | Sk is a vector of q numbers, k = 1, ..., T]... 阅读全帖 |
|
m******t
发帖数: 273 | 13 【 以下文字转载自 Statistics 讨论区 】
发信人: myregmit (myregmit), 信区: Statistics
标 题: Predict values of vectors by other vectors generated by black box
functions
发信站: BBS 未名空间站 (Sun Mar 2 11:38:56 2014, 美东)
Hi,
I need to solve a problem about predicting values of some numerical vectors
by using other numerical vectors with all these vectors in the same vector
set, which is generated by one or more black box functions.
Given a vector space:
P =[S_1, S_2, …, S_T | Sk is a vector of q numbers, k = 1, ..., T]... 阅读全帖 |
|
m******t
发帖数: 273 | 14 【 以下文字转载自 Statistics 讨论区 】
发信人: myregmit (myregmit), 信区: Statistics
标 题: Predict values of vectors by other vectors generated by black box
functions
发信站: BBS 未名空间站 (Sun Mar 2 11:38:56 2014, 美东)
Hi,
I need to solve a problem about predicting values of some numerical vectors
by using other numerical vectors with all these vectors in the same vector
set, which is generated by one or more black box functions.
Given a vector space:
P =[S_1, S_2, …, S_T | Sk is a vector of q numbers, k = 1, ..., T]... 阅读全帖 |
|
m******t
发帖数: 273 | 15 Hi,
I need to solve a problem about predicting values of some numerical vectors
by using other numerical vectors with all these vectors in the same vector
set, which is generated by one or more black box functions.
Given a vector space:
P =[S_1, S_2, …, S_T | Sk is a vector of q numbers, k = 1, ..., T]
Find a sub-group of vectors g = {S_d | d belongs to 1, …, T } and a
function h( S_d )
Such that
Difference between the value of h(S_g) and S_r is minimized
set g + set r = set P
... 阅读全帖 |
|
w******y
发帖数: 4871 | 16 GENERAL ANESTHESIA
Induction — If examination of the upper airway suggests that intubation
will not be problematic, the following sequence is used for providing
general anesthesia to the gravida:
•A nonparticulate antacid is generally given preoperatively to
alkalinize gastric contents. Some practitioners also administer
metoclopramide or an H2 blocker as prophylactic measures to minimize the
risk and severity of aspiration (see 'Reduction of gastric acidity/volume'
above).
•Just pri... 阅读全帖 |
|
|
z**********e
发帖数: 22064 | 18 Advice for U.S. College Students Abroad Be Aware of Foreign Intelligence
Threat
04/14/14
Three years ago, Glenn Duffie Shriver, a Michigan resident and former
college student who had studied
in the People’s Republic of China (PRC), was sentenced to federal prison in
the U.S. for attempting to
provide national defense information to PRC intelligence officers. (See
sidebar for more on the case.)
According to the Institute of International Education, more than 280,000
American students studied
abro... 阅读全帖 |
|
f******s
发帖数: 713 | 19 你这个假设是错误的，平均20万当量的核弹头即使在平原上也不可能摧毁50公里半径的
东西，看下这个链接 http://www.nationalterroralert.com/nuclear/
100万当量的炸弹，在10.84公里半径距离上 “Residences are moderately damaged.
Commercial buildings have sustained minimal damage. Twenty-five percent of
the population between the 2 and 1 psi rings have been injured, mainly by
flying glass and debris.”假设minimal damage 算是核武器的覆盖面积, 那么30000
件20万当量的核武器覆盖的面积是 30000×20/100×3.1416×10.84X10.84=2214934
kilometer square, 大约相当于1.48% of 地球陆地。远远不能无缝覆盖。
可虑的是核冬天，但这个从来没有事实证明过，美国科学家试炸第一 |
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S*********g
发帖数: 24893 | 20 南京彭宇一案，虽然可能判决不公，但是起到了一个正面的副作用，就是唤起民众对法
律的敬畏之心，做任何事之前，都要掂量掂量，会不会受到法律的惩罚。
18个冷血的路人，从侧面体现了民众日益增强的法制观念（简单地说，就是每一位公民，都尽量minimize触犯法律的probability），同时也体现了市场经济的日益完善（简单地说，就是任何行为，在法律允许的范围内，maximize profit & minimize loss）。 |
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d*********g
发帖数: 2906 | 21 批判日本对于南京大屠杀和慰安妇的否认
作者是“南京”纪录片的导演，斯坦福的讲师。
http://www.latimes.com/news/opinion/commentary/la-oe-guttentag-
Revisionism Tokyo-style
Japan's leaders still won't acknowledge their country's wartime atrocities.
This month 75 years ago, the people of Nanking , China's ancient capital
city, were in the midst of one of the worst atrocities in history, the
infamous Rape of Nanking. The truth of what actually happened is at the
center of a bitter dispute between China and Japan that continues to play
out i... 阅读全帖 |
|
b*****d
发帖数: 61690 | 22 看成非法移民了.
http://blog.visitorscoverage.com/obamacare-for-us-visa-workers/
The new Affordable Care Act (ACA), also known as ‘ObamaCare’, requires
that everyone in the US have minimal essential health insurance – or else
pay the penalties. The consequences of not having minimal health care
coverage can be extreme: fees that increase every year after 2014 plus you
have to pay for all of the costs for your medical treatment – even
emergency care.
It is important to understand that ACA is not governme... 阅读全帖 |
|
c***z
发帖数: 6348 | 23 Do you know calculus?
Say you have a function y = f(x), where f has some parameters, and follow
some basic requirement (e.g. continuous, but this is not necessary, because
saw shaped functions work better).
Basically it is using the chain rule in calculus to move the parameters
around for minimal prediction error, which is the difference between the
predicted y and real y.
When error is minimized, we think we found a correlation between the inputs
and outputs, and try to apply that correlation t... 阅读全帖 |
|
b***y
发帖数: 14281 | 24 这说明美国的司法有问题。这样直接射杀，无论杀了多少人，所有黑锅都让一个杀手背
了，完全砍掉了全社会的反思和检讨的程序，虽然是minimize 了社会成本和动荡，但
也minimize了healing和lessoning。对家属必然在心中留下一个巨大的空洞。
★ 发自iPhone App: ChineseWeb 11
★ 发自iPhone App: ChineseWeb 11 |
|
D*****i
发帖数: 8922 | 25 Pentagon Spokesman Captain Jeff Davis issued a statement in which he
confirmed that US officials warned Russian counterparts ahead of the strikes
over a "deconfliction line".
Here's an excerpt from his statement, and
The strike was conducted using Tomahawk Land Attack Missiles (TLAMs)
launched from the destroyers USS Porter and USS Ross in the Eastern
Mediterranean Sea. A total of 59 TLAMs targeted aircraft, hardened aircraft
shelters, petroleum and logistical storage, ammunition supply bunkers,... 阅读全帖 |
|
W*****B
发帖数: 4796 | 26 LASIK eye surgery should be taken off market, former FDA adviser says
LASIK eye surgery has been popular for more than 20 years, with an estimated
20 million Americans undergoing the procedure to correct nearsightedness
and improve distance vision. But some patients say the surgery has ruined
their eyesight.
The quick, minimally-invasive surgery uses a laser to cut a flap to reshape
the cornea at the front of the eye. Now an expert who once backed LASIK is
campaigning to get it off the market.
A... 阅读全帖 |
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b*********3
发帖数: 1709 | 27 This is scary. Even today, our own WaPo continues to try to shift the blame
to the Chinese for our disastrous response by suggesting that the Chinese
were minimizing the issues. The truth is that China locked down 50 million
people when the total caseload in their country stood at 600. Just which
part of that is a minimized response? Having seen SARS first hand in 2003,
they reacted in a manner initially criticized by us as being draconian. We
started the first shelter in place in the Bay Are... 阅读全帖 |
|
发帖数: 1 | 28
minimize
“纽约当下的情况估计差不多和意大利封城前后差不多，你就大概能理解，巨巨
minimize消息到个什么程度”
这个东西你要是有证据就摆出来，
就靠上嘴唇搭一下下嘴唇的东西，和放个屁没啥区别 |
|
s******n
发帖数: 518 | 29 【 以下文字转载自 History 讨论区 】
发信人: shaodian (有熊), 信区: History
标 题: 美国生物实验室泄露
发信站: BBS 未名空间站 (Sun Mar 22 15:25:05 2020, 美东)
Google翻译一次只能3900字符。
https://www.usatoday.com/story/news/2015/05/28/biolabs-pathogens-location-
incidents/26587505/
Investigation reveals hundreds of accidents, safety violations and near
misses put people at risk
Alison Young and Nick Penzenstadler, USA TODAY
Vials of bioterror bacteria have gone missing. Lab mice infected with deadly
viruses have escaped, and wild rodents have b... 阅读全帖 |
|
g********d
发帖数: 4174 | 30 Rick Perry's "Texas Miracle" Con Job
Posted: 8/12/11 03:51 PM ET React Important
Texas governor and reported GOP presidential candidate Rick Perry is the
nation's greatest political con artist. His so called "Texas Miracle" has
been totally debunked as a fraud. Yet Perry, with generous help from
conservative business leaders, tea party acolytes, and suddenly revved up
evangelicals will keep the con very much alive. The so-called miracle that
Perry and his backers peddle is of course that Texas i... 阅读全帖 |
|
l****z
发帖数: 29846 | 31 October 30, 2012 Doug Johnson
The new POLITICO/George Washington University Battleground Tracking Poll of
1,000 likely Ohio voters – taken from last Monday through Thursday – shows
Obama ahead of Romney by 1 percentage point, 49 percent to 48 percent. That
represents a 3-point swing in Obama’s direction from a week ago but
reflects a race that remains statistically tied. Even the swing is within
the margin of error, so it is possible the candidates were tied last week
when Romney lead by 2 perc... 阅读全帖 |
|
l****z
发帖数: 29846 | 32 Posted: Nov 16, 2012 9:16 AM Updated: Nov 16, 2012 9:17 AM
By FOX News
Former CIA Director David Petraeus testified in a closed-door hearing Friday
morning that his agency determined immediately after the Sept. 11 Libya
attack that "Al Qaeda involvement" was suspected -- but the line was taken
out in the final version circulated to administration officials, according
to a top lawmaker who was briefed.
Rep. Peter King, R-N.Y., who spoke to reporters after Petraeus testified
before the House Intel... 阅读全帖 |
|
l****z
发帖数: 29846 | 33 在多哈大会上，只有37国决定延续京都协议，它们占全球温室气体排放量的15%
Doha Fails Utterly – Only 37 Countries Agree To Extend Old Kyoto Treaty! “
Lots Of Declarations Of Intent”
By P Gosselin on 8. Dezember 2012
The German media report that only a totally lame climate treaty compromise
was reached in Doha: Kyoto I will be extended until 2020.
Sun sets on Doha. Minimal compromise reached. Source: www.cop18.qa
For those calling for rapid reductions in CO2 emissions, the result in Doha
can only be described as an utter disaster. T... 阅读全帖 |
|
c*****g
发帖数: 21627 | 34 Michael Lewis: Did Goldman Sachs Overstep in Criminally Charging Its Ex-
Programmer?
A month after ace programmer Sergey Aleynikov left Goldman Sachs, he was
arrested. Exactly what he’d done neither the F.B.I., which interrogated him
, nor the jury, which convicted him a year later, seemed to understand. But
Goldman had accused him of stealing computer code, and the 41-year-old
father of three was sentenced to eight years in federal prison.
Investigating Aleynikov’s case, Michael Lewis holds a s... 阅读全帖 |
|
l****z
发帖数: 29846 | 35 Sanitizing Higher Education
By Robert Weissberg
The intellectual damage caused by forcing the university to admit
academically ill-prepared minority students is seemingly endless, but just
when it seems that matters cannot get any worse, they do.
The latest installment of this crusade now occurs at the University of
Illinois-Urbana, a school where I taught political science for 28 years, so
I know this nonsense first hand. Here’s the sorrowful tale (for a Harvard
version, see here).
According t... 阅读全帖 |
|
l****z
发帖数: 29846 | 36 Hillary Clinton Is Explaining - And Losing
12:00 PM, Aug 13, 2015 • By SHOSHANA WEISSMANN
There's a saying in politics, "when you're explaining, you're losing." It's
applied a few ways, but it generally means that in situations in which
politicians have to explain away a scandal or gaffe, as they're explaining,
their supporters become somewhat dismayed or begin to question the candidate
, and potential supporters are turned off.
Hillary Clinton is explaining. And losing.
First, take Correc... 阅读全帖 |
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w*****2
发帖数: 1458 | 37 http://thefederalist.com/2015/11/24/campus-race-warriors-demand
Hiring more African-American faculty, as campus protestors are demanding,
will necessarily reduce the percentage of Asian faculty.
It may be coincidental that the photojournalist the University of Missouri
social justice warriors attacked in public was Asian-American, but their
reaction wasn’t. Concerned Student 1950 tweeted, “It’s typically white
media who don’t understand the importance of respecting black spaces.”
Liberals have a... 阅读全帖 |
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t*******s
发帖数: 492 | 38 Also, I assume you hate welfare. Raising minimal wage is also a way to
encourage work, and if republican can control all congress and White House,
and do not adjust welfare up, then the higher minimal wage is effectively
reducing welfare by higher inflation. |
|
g********2
发帖数: 6571 | 39 September 4, 2016
Analysis of FBI Reports: China more likely to have Hillary’s emails, not
Russia
By Richard Henry Lee
From an analysis of the FBI document dump (Part 1, Part 2) concerning
Hillary’s email use and her foreign travel schedule, it is apparent that
the Chinese are more likely to have gained access to Hillary’s emails than
Russia. Other countries would have had opportunities as well.
Hillary’s email server was most vulnerable from mid to late January to late
March 2009, when the emai... 阅读全帖 |
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t*******s
发帖数: 492 | 40 I support trump and I support minimal wage as well. Under the current
economic situation, the country needs a bit higher inflation (preferably
driven by labor cost increase, not momentary base expansion) for many
reasons. Higher minimal wage is a perfect candidate for this.
Also, trump's infrastructure plan sparked higher inflation expectation, with
10yr tsy sold off 50bps post-election, that's also a good thing in many
ways. |
|
发帖数: 1 | 41 Ryan 說了，“在可預見的未來，Obamacare is the law of the land”。川普的行政
命令是關於歐記健保的最新標準，它對於歐記健保未來會帶來什麼影響？已經產生的影
響有哪些？最重要的，有沒有人已經被影響到了，好的或壞的？
以前似乎沒人仔細分析過這個行政命令，現在恐怕必須思考一下了。我沒找到，如果有
人知道請分享，關於此命令對歐記健保的影響。
EXECUTIVE ORDER
- - - - - - -
MINIMIZING THE ECONOMIC BURDEN OF THE PATIENT PROTECTION AND AFFORDABLE CARE
ACT PENDING REPEAL
By the authority vested in me as President by the Constitution and the laws
of the United States of America, it is hereby ordered as follows:
Section 1. It is the policy of my Administrati... 阅读全帖 |
|
g****u
发帖数: 1 | 42 Care and Maintenance Tips Keep Your Car Running in Top-Notch Condition
We’ve compiled our best expert advice, surprising tricks, and car care tips
to prolong the life of your automobile!
1. Be patient during the break-in period
You’ve bought your dream car and now you want to make it last at long as
possible in top condition. Here are some things to remember as you pull it
out of the dealer’s lot:
During the break-in period, typically the first 1,000 miles (1,600 km), keep
your speed under 55 mp... 阅读全帖 |
|
d***a
发帖数: 13752 | 43 租的车有跟车走的liability保险，在加州的除外。
http://en.wikipedia.org/wiki/Car_rental#Insurance_.2F_waivers
Although frequently not explicitly stated, US car rental companies are
required by respective state law to provide minimal liability coverage,
except in California, where the driver is solely responsible. This covers
costs to a third party in the event of an accident.[5] In most states, it is
illegal to drive a car without liability coverage. The rental car companies
maintain liability insurance on their ve... 阅读全帖 |
|
t**********3
发帖数: 12623 | 44 DONT PUMP FULL TANK OF PETROL
Many of us are not aware that the petrol kiosk pump has a return pipe-line (
in Pink). When the petrol tank (in the car) reaches full level, there is a
mechanism to trigger off the pump latch and at the same time a return-valve
is opened (at the top of the pump station) to allow excess petrol to flow
back into the pump. But the return petrol has already pass through the meter
, meaning you are donating the petrol back to the Oil Dealer.
Also only fill up your car or... 阅读全帖 |
|
a******o
发帖数: 16625 | 45 丰田UR系列发动机每一个型号都很牛逼
Toyota UR engine
From Wikipedia, the free encyclopedia
Toyota UR engine
Toyota 1UR-FSE Engine.JPG
Overview
Manufacturer Toyota Motor Corporation
Production 2006–
Combustion chamber
Configuration DOHC 90° V8
Chronology
Predecessor Toyota UZ engine
The Toyota UR engine family is a 32-valve quad-camshaft V8 piston engine
series which was first introduced in 2006 as the UZ series it replaced began
phasing out. Production started with the 1UR-FSE engine with D4-S di... 阅读全帖 |
|
e******8
发帖数: 741 | 46 Minimal deposit $25 when opening
$500 DD one month or $1500 minimal daily balance
Asking for $10.
Paypal or Chase quickpay |
|
s*******x
发帖数: 427 | 47 Software Developer
We are seeking a Software Developer to develop and maintain components of
the finite element solver.
Responsibilities:
• Develop finite element/optimization software within OptiStruct
team
• Maintain and develop utility software for builds and qa process
for OptiStruct and other solvers
• Develop and expand internal data structures and base algorithms
in finite element solvers
• Participate in tuning and optimization of specific routines/
al... 阅读全帖 |
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J*****n
发帖数: 4859 | 48 【 以下文字转载自 JobHunting 讨论区 】
发信人: Jadeson (紫昂德帅), 信区: JobHunting
标 题: Need a Jr developer
发信站: BBS 未名空间站 (Thu Mar 12 11:18:29 2015, 美东)
Great C#.Net Developer position that is co-located with the Front Office
Securities business and is part of the global trading technology team. You
will have the opportunity to work on the real time trading platforms as well
as working closely with the traders to automate trading strategies. This
role is unique in that it is both Development and Ops focussed (on ... 阅读全帖 |
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