|
a****a
发帖数: 3905 | 2 Constance Holden
Next to our own selves, there is no more interesting hominid than the Neande
rtal. Neandertals are the humans manqué, the evolutionary dead end: eerily
like us, but different in major ways. And they are the subject of one of the
hottest ongoing debates in anthropology.
How smart were these big-brained, stocky-bodied people, who inhabited Europe
and the Middle East starting about 200,000 years ago? And what caused their
relatively abrupt disappearance by 30,000 years ago? The Nea |
|
J*****3
发帖数: 4298 | 3 笑死我了，还来玩黑白颠倒的吗？
我给你全文吧，这么撒谎的话，是耶稣教的吗？撒谎神不喜悦
这篇文章是基督教手册用来歪曲人类进化不成立的，是JAMES给我了文章的一个LINK，但是文章看不全，我根据作者名字找到了全文，也读了，发现，文章根本没有说进化不成立，他们断章取义，黑白颠倒地撒谎。我BS这种恶心的行为。
“5、大概在97年，一个著名的非基督徒考古学家，在非洲发现的所谓人类化石，把一
直以来公认的人类进化顺序，猿人——直立人——能人——智人，给彻底推翻了。目前
人类进化链条重新归零，变为空白。”
原文
http://news.nationalgeographic.com/news/2010/05/100506-science-
翻译：
“Even if the new result doesn't quite settle the debate about whether
Neandertals mixed with modern humans, it does underscore how different they
were from our own lineage. And t... 阅读全帖 |
|
J*****3
发帖数: 4298 | 4 我看完了，我找到文章了，不是你们小册子说的那样，这个才是文章的结论，“ So it
seems that the Neandertal sequence reinforces what this skeleton told the
world when it was first discovered: that humans evolve just like everything
else. ”
http://www.unl.edu/rhames/neander/neander.htm
ANTHROPOLOGY:
DNA From an Extinct Human
July 10, 1997
Patricia Kahn and Ann Gibbons
"It's what happens to [other kinds of] populations," says paleontologist Rob
Foley of Cambridge University in the United Kingdom. "But in the case of
Neandertals, we get ... 阅读全帖 |
|
V****n
发帖数: 651 | 5 性别，种族等的区别根本上都是由基因决定的。
不同基因造成的差别很容易理解,比如欧亚人和尼安德特人混血，而非洲人没有。见发
表于科学的经典文章：
http://www.sciencemag.org/content/328/5979/710.full
摘要节选：
We show that Neandertals shared more genetic variants with present-day
humans in Eurasia than with present-day humans in sub-Saharan Africa,
suggesting that gene flow from Neandertals into the ancestors of non-
Africans occurred before the divergence of Eurasian groups from each other.
相同基因也可以造成差别，比如男女基因表现方式的不同。X染色体有2000个左右基因
，目前估计40%左右影响智力的基因在X染色体上。
一个基因，女性表征可为AA，Aa,... 阅读全帖 |
|
c*******r
发帖数: 334 | 6 来说说我近两三年来比较喜欢看/听的一套书吧。
Earth’s Children 《大地的孩子们》 作者是Jean M. Auel。系列是这样的：
The Clan of the Cave Bear (1980) 洞穴熊部族
The Valley of Horses (1982) 马儿的山谷
The Mammoth Hunters (1985) 狩猎猛犸象的人
The Plains of Passage (1990) 旅行经过的原野
The Shelters of Stone (2002) 有巨石的隐蔽所
The Land of Painted Caves (2011) 有洞穴岩壁画的土地
最开始的时候，是从图书馆随便借到的The Valley of Horses 的audio book来听，很
喜欢，之后到网上查了一下，发现是一个系列，于是又陆续借了之前和之后的几本书来
看，来听，直到最后一本书出来。
这套书，场景设定在大约二、三万年前的冰河时期，欧洲的旧石器时代晚期。
书中以克罗马农人为新人类，和书中的另一类人，古老... 阅读全帖 |
|
j*******7
发帖数: 6300 | 7 About this --
5、大概在97年，一个著名的非基督徒考古学家，在非洲发现的所谓人类化石，把一直
以来公认的人类进化顺序，猿人——直立人——能人——智人，给彻底推翻了。目前人
类进化链条重新归零，变为空白。
I think that refers to this link --
http://www.sciencemag.org/content/277/5323/176.summary
DNA From an Extinct Human
Patricia Kahn and Ann Gibbons
In a technical tour de force, scientists from Germany and the United States
for the first time extracted and analyzed DNA from a Neandertal. The
mitochondrial DNA sequence they found offers a new kind of evidence for the
view that Neandertals w... 阅读全帖 |
|
m***T
发帖数: 11058 | 8 想看具体的individual文章们，请follow最下面的link.
NEW YORK (GenomeWeb News) – In a very busy year for news in the 'omics and
molecular diagnostics industries, an article about an acquisition topped the
list of the most-read stories for the year on GenomeWeb Daily News, while
restructurings, lawsuits, and one firm's IPO plans made it into the top 10.
Here are the top 10 for the year:
1) Life Technologies CEO Defends Price for Ion Torrent, Dismisses Illumina's
PCR System
2) Roche Restructuring Plan Includes 4,8... 阅读全帖 |
|
p*****c
发帖数: 20445 | 9 Michael Rape, Ph.D.
University of California, Berkeley
Michael Rape’s love of science began in the basement of his parent’s house
, where he used to conduct rudimentary biochemistry experiments. Today, he
uses far more sophisticated methods to understand a complex process critical
to nearly all organisms: ubiquitylation. The term describes the attachment
of a regulatory protein called ubiquitin—named for its ubiquity—onto other
proteins. Ubiquitin tags communicate a wealth of information to the ... 阅读全帖 |
|
m******g
发帖数: 467 | 10 说好的希望每周更新呢？不过是“希望”嘛，很快补上。
Science 14.1.31
小知识：
1. Neandertals and Moderns Made Imperfect Mates
Two papers with different methodology
(whether or not use Neandertal's reference genome)
Lower fertility in hybrids
Regions determined (desert in X chromosome & traits related)
2. Online Video Game Plugs Players Into Remote-Controlled Biochemistry Lab
3. Editing of Targeted Genes Proved Possible in Monkeys
Using CRISPR in primates
4. Chemical Warfare in the Battle of the Sexes
In D. melanogaster a... 阅读全帖 |
|
G***G
发帖数: 16778 | 11 这个所谓的基因证据是怎么测试的？为什么可靠？
另外，根据什么准确测定一个人骨头的年代？
为何5万年以内的人头盖骨没有发现？如果发现的，都是类似neandertal这样的几十万
年以前的人头盖骨？ 难道不是离现在越近，发现的应该越多吗？
因为没发现5万年以内的人头盖骨，就说homo erectus走出非洲后，把neandertal都杀
死了。好像缺乏有效证据。 |
|
V****n
发帖数: 651 | 12 1-4% among Euroasians (nonAfricans)
see:
http://www.sciencemag.org/content/328/5979/710.full
"Thus, the actual amount of interbreeding between Neandertals and modern
humans may have been very limited, given that it contributed only 1 to 4% of
the genome of present-day non-Africans."
On average 2.5%.
I have 3.0%, about 65 percentile. |
|
l***y
发帖数: 4671 | 13 查了一下，没找到啊。
2004 年的时候 PLoS Biol 的文章证明人类 gnome 和 mt gnome 都没有尼人基因的证
据：
Currat M, Excoffier L (2004) Modern Humans Did Not Admix with Neanderthals
during Their Range Expansion into Europe. PLoS Biol 2(12): e421. doi:10.1371
/journal.pbio.0020421
Serre D, Langaney A, Chech M, Teschler-Nicola M, Paunovic M, et al. (2004)
No Evidence of Neandertal mtDNA Contribution to Early Modern Humans. PLoS
Biol 2(3): e57. doi:10.1371/journal.pbio.0020057
去年的 PNAS 依然是这个观点：
Strong reproductive isolation between hum... 阅读全帖 |
|
|
|
b*******s
发帖数: 470 | 16 目前主流科学界的意见是：“狗是“天生”出来给人当好伙伴的”。今年四月份《
Science》有一期专门讲狗的自然驯化的专题：
Most experts now think dogs domesticated themselves. Early humans left piles
of discarded carcasses at the edges of their campsites—a veritable feast,
the thinking goes, for wolves that dared get close to people. Those wolves
survived longer and produced more pups—a process that, generation by
generation, yielded ever-bolder animals, until finally a wolf was eating out
of a person's hand. Once our ancestors realized the utility of the... 阅读全帖 |
|
|
A*********g
发帖数: 268 | 18 Neandertaler，生活在更新世晚期，旧石器时代中期的“古人”，因为其活动的遗迹最早
在Duesseldorf附近的Neandertal流域发现而得名，分布在欧洲、北非、中亚和西亚一带
，呵呵，我很想去参观。
www.neanderthal.de
Neanderthal Museum Association
The Neanderthal Museum is more than just a museum! It is a place of learning,
a conference venue, a communications forum, and a documentation and research
centre on the Neanderthals. With its broad range of cultural facilities and
special exhibitions, it has much to offer to visitors of all kinds. If you
would like to support our activities |
|
|
J*****3
发帖数: 4298 | 20 我看完了，我找到文章了，不是你们小册子说的那样，这个才是文章的结论，“ So
itseems that the Neandertal sequence reinforces what this skeleton told
theworld when it was first discovered: that humans evolve just like
everything else. ”
http://www.unl.edu/rhames/neander/neander.htm
你读过人家的文章了没有，文章的结论清楚地说了，人类的进化和其他的是一样的。 |
|
j*******7
发帖数: 6300 | 21 你还真会看文章。最后引用并非作者的一句“seems”就成了结论？
结论应该是：
Neandertals were not the ancestors of modern humans, according to new
mitochondrial DNA data.
it
everything
Rob |
|
J*****3
发帖数: 4298 | 22 "Even if the new result doesn't quite settle the debate about whether
Neandertals mixed with modern humans, it does underscore how different they
were from our own lineage. And that implies that "up to 200,000 or 300,000
years ago, humans evolved just like gorillas and everything else," says Ward
, perhaps with several contemporaneous, diverse human species."
-- 文章否定进化论了吗？再唐几句，其他物种进化是有分岔的（进化树），现在这个文章讨论的是人类进化是直线的呢还是也有分岔，就和后面BBC/TIMES的新闻报道一样，一个意思，被你们歪曲到人类进化不成立。给你科普下
退一步，我不信基督教只要我读下圣经就可以了，不需要知道更多的关... 阅读全帖 |
|
J*****3
发帖数: 4298 | 23 再给你贴一次，眼花戴眼镜
"Even if the new result doesn't quite settle the debate about whether
Neandertals mixed with modern humans, it does underscore how different they
were from our own lineage. And that implies that "up to 200,000 or 300,000
years ago, humans evolved just like gorillas and everything else," says Ward
, perhaps with several contemporaneous, diverse human species."
-- 文章否定进化论了吗？再唐几句，其他物种进化是有分岔的（进化树），现在这个
文章讨论的是人类进化是直线的呢还是也有分岔，就和后面BBC/TIMES的新闻报道一样
，一个意思，被你们歪曲到人类进化不成立。给你科普下 |
|
J*****3
发帖数: 4298 | 24 笑死我了，你不是直接作案，不过那天是你给我的这个作者的文章，
我给你LINK，你那天怎么不敢回复一个字，灰溜溜地跑了，造谣不打草稿吗
http://www.mitbbs.com/article_t1/TrustInJesus/753023_0_4.html
发信人: Judy123 (大肥猫), 信区: TrustInJesus
标 题: Re: 请haitaob (求道的人)回答问题
发信站: BBS 未名空间站 (Fri Mar 23 23:43:54 2012, 美东)
再给你贴一次，眼花戴眼镜
"Even if the new result doesn't quite settle the debate about whether
Neandertals mixed with modern humans, it does underscore how different they
were from our own lineage. And that implies that "up to 200,000 or 300,000
years ago, humans evolve... 阅读全帖 |
|
i*e
发帖数: 859 | 25
there is some evidence showing that they might be able to mate
and have hybrids, based on studies on the skeletons of lots of
neandertals, the other homo sapien at that time, including the
assumptive direct ancestor of modern european, and those somewhat
in between. |
|
a****o
发帖数: 1786 | 26 Greg Hannon shared the story in HMS on Monday. This array-based capture
method is so useful for sequecing ancient DNA. |
|
P****d
发帖数: 564 | 27 Take home message: Neanderthal men were much more successful at luring
sapiens women then the sapiens men with Neanderthal women!
Fine print: alternative hypotheses exist, but won't make NY Times front page
. |
|
d*****u
发帖数: 17243 | 28 personally,我一直相信白人继承了很多neanderthals的traits
page |
|
P****d
发帖数: 564 | 29 I guess the natural follow up of this paper to investigate the allele
frequency of the Neanderthal genes. Anyone wants to bet that it's highest
in France and Spain? |
|
C***k
发帖数: 1570 | 30 Svante Paabo just gave a talk about this here this afternoon... |
|
s******y
发帖数: 28562 | 31 我本来也是这么想的，因为neanderthal 是红头发白皮肤的，
但是这个文章的结论是neanderthal 的基因其实和现代亚洲人更相近。
其次是欧洲人，和非洲人最远。 |
|
g*********d
发帖数: 233 | 32 发表在基因图谱年会的一项跨文化研究指出，东方人的发丝比西方人粗50％的现象
和一段EDAR
基因有关.
SAN DIEGO, CALIFORNIA--Whether you have a poker-straight black mane
or frizzy blond locks, your hair depends on your ancestry. Now
researchers have come closer to figuring out just how hair traits are
passed down. According to a talk presented here last week at the annual
meeting of the American Society of Human Genetics, a single genetic
variant may explain why East Asians have thicker hair fibers than other
populations. The discovery ... 阅读全帖 |
|
l**********1
发帖数: 5204 | 33 是呀 大猩猩 Chimp (Pan troglodytes) 的ES 细胞会有问题吗?
//genome.ucsc.edu/Neandertal/
//genome.ucsc.edu/cgi-bin/hgGateway |
|
s******y
发帖数: 28562 | 34 Neandertal 的相貌恢复图，怎么样？象白人吧？（其实更象Chuck Norris. Lol) |
|
m******g
发帖数: 467 | 35 PNAS 14.2.11
推荐：
1. Recursive genomewide recombination and sequencing reveals a key
refinement step in the evolution of a metabolic innovation in Escherichia
coli
稍微了解一下：
1. Separating endogenous ancient DNA from modern day contamination in a
Siberian Neandertal
2. Stability-activity tradeoffs constrain the adaptive evolution of RubisCO |
|
m******g
发帖数: 467 | 36 Science 14.02.28
推荐：
1. Lost in Transition: Start-Up of Glycolysis Yields Subpopulations of
Nongrowing Cells
稍微了解一下：
1. Silencing in Fragile X Syndrome Promoter-Bound Trinucleotide Repeat mRNA
Drives Epigenetic
2. Resurrecting Surviving Neandertal Lineages from Modern Human Genomes
Look at proportions and methodology
小知识：
1. Out of Beringia?
shrub tundra refugium
2. Phonetic Feature Encoding in Human Superior Temporal Gyrus |
|
m******g
发帖数: 467 | 37 Science 14.03.28
推荐：
1. Building the Ultimate Yeast Genome
Total Synthesis of a Functional Designer Eukaryotic Chromosome
the power of students' army, haha
稍微了解一下：
1. Oldest Homo sapiens Genome Pinpoints Neandertal Input
小知识：
1. Tweaking a Switch
a single-molecule chase assay
equilibrium binding of the repressor to its operator
2. Synthetic Biologists Design 'Living Materials' That Build Themselves
3. Quantifying Global International Migration Flows |
|
m******g
发帖数: 467 | 38 Science 14.04.18
推荐：
1. Ancient DNA Holds Clues to Gene Activity in Extinct Humans
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
harnessing the natural degradation processes
of methylated and unmethylated cytosines
unmethylated cytosines decay with time to uracils
methylated cytosines decay to thymines
小知识：
1. Sleep Tight, Fly
sleep pattern characteristic of youthful flies is critical to brain
development
2. Changing Assemblages
Assemblage Time Series Reveal Biodiv... 阅读全帖 |
|
m******g
发帖数: 467 | 39 Science 14.05.02
推荐：
1. Reconstructing the DNA Methylation Maps of the Neandertal and the
Denisovan
小知识：
1. Male Scent May Compromise Biomedical Studies
The mice that didn't show pain had been handled by male students
Rodents exposed to male odors were actually feeling less pain
2. Therapeutic Cloning Reaches Milestone
Two teams have independently derived human embryonic stem cells
By cloning adult skin cells
3. Genomic Signatures of Specialized Metabolism in Plants
How algae and land plants ha... 阅读全帖 |
|
m******g
发帖数: 467 | 40 PNAS 14.05.06
稍微了解一下：
1. Hypermutable DNA chronicles the evolution of human colon cancer
A simple PCR-based assay
Interrogating somatic variation in hypermutable polyguanine (poly-G) repeats
2. Exploration of sequence space as the basis of viral RNA genome
segmentation
小知识：
1. Patterns of coding variation in the complete exomes of three Neandertals
2. Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes
to ferns |
|
发帖数: 1 | 41 基因证据显示是这样的，现代非非洲人的祖先都是非洲人，属于晚期智人，大约5万年
以前迁出非洲。
homo erectus在现代人出非洲之前就灭绝了。早期智人比如neandertal也在3万年前灭
绝了。
Ape
came |
|
发帖数: 1 | 42 非洲起源说是遗传学证据，基本不可能被推翻。
而且summary里写到
Some features are ancestral and similar to those of earlier eastern Eurasian
humans, some are derived and shared with contemporaneous or later humans
elsewhere, and some are closer to those of Neandertals.
即便头骨是H sapiens，也可能像Neanderthal一样最后灭绝的，只在现代人基因组中留
下极少(if any)的admixture。
这么完整，脑容量高达1800cc,，基本否定了东亚现代人类的非洲起源说了吧。 |
|
M**********n
发帖数: 432 | 43 Homosapien evolved to human being, and then went out of Africa.
Neandertals went extinct. |
|
i*****s
发帖数: 15215 | 44 罕见的冻尸：这具在俄罗斯发现的非常罕见的小长毛象冻尸距今已有42 000年，包
含大量有用的信息。不过，想要了解这种动物曾经赖以生存的生物机能的精确细节，只
能依靠DNA。
生物技术的发展使我们能够重新构建灭绝动物的古基因，并进而研究古生物机体活
着的时候如何运转。利用这种方法，科学家揭开了史前巨兽长毛象如何适应冰河时代严
酷环境的谜题。
撰文 凯文•L•坎贝尔(Kevin L. Campbell) 迈克尔•霍夫瑞特(
Michael Hofreiter)翻译 黄修远 李辉
150多年以来，科学家一直主要依靠骨骼和牙齿化石，来重塑史前生物。骨架能够
告诉科学家这些古生物的体型大小和身体形态；骨骼上的肌肉附着点显示了这些生物究
竟有多么强壮，以及它们可能的移动方式；牙齿形状和磨损程度则揭示了它们的食物种
类。总而言之，研究者们必须想方设法从这些坚硬的化石中获取大量的信息。在某些偶
然的情况下，他们会有机会获得保存完好的干尸或者冻尸。这使得研究者们能够得到更
多细节用以重塑，例如毛发的长度、耳朵的形状、动物最后一顿晚餐所吃的东西等等。
尽管科学家已经能够... 阅读全帖 |
|
