Which next-generation DNA sequencing methods is the best for measuring
nuclotide frequency in sequencing, Roche/454 FLX pyrosequencer, Illumina
genome analyzer,Applied Biosystem SOLid sequencer? Thanks.
It's off by a factor of 2e3 based on my calculation. Did you take into
account that DNA is double-stranded? Also, make sure the nuclotide weight
conversion is based on Dalton, not kilo-Dalton.