关于peptoid的讨论汇总 - 话题女王

全部话题 - 话题: peptoid

f*****l
发帖数: 3

来自主题: Postdoc版 - Postdoc position available at Pacific Northwest National Laboratory

http://pnnl.jobs/richland-wa/post-doctorate-ra-peptoid-synthesi
Job ID: 304908
Directorate: Physical & Computational Sciences
Division: Physical Sciences
Group: Materials Sciences
.
Job Description
The successful candidate will be a synthetic chemist or materials scientist
responsible for peptoid synthesis, purification and assembly. This
researcher will also be involved in exploiting peptoid assemblies for
applications. Instruments that will be used for peptoid synthesis and
purification includ... 阅读全帖

c*******u
发帖数: 175

来自主题: Chemistry版 - 如何改造peptide 来减少in vivo enzymatic degradation

peptoid

c******y
发帖数: 193

来自主题: Chemistry版 - 如何改造peptide 来减少in vivo enzymatic degradation

Thank you all for the reply!
1) Which amino acid in the peptide should be changed to d-AA? or any amino
acid change could prevent the peptide degradation.
2) Cyclization means make the whole peptide be cyclic, or just part of it?
Are there any reference on the cyclization protect peptide?
3) thanks for sharing peptoid! Are there any review on this?
Thank you again! Good night, sleep tight!

T****O
发帖数: 407

来自主题: Chemistry版 - 如何改造peptide 来减少in vivo enzymatic degradation

1. Make it all d-AA with the reversed sequence, a.k.a., Retro-Inverso
2. Whoever saying cyclization can prevent degradation is ... anyway. It's
easy to try and not expensive.
3. Peptoids are very different. Don't branch out too much.
Finally, are you sure your peptides were broken down by enzymes in vivo?
How did you analyze or track peptides in vivo?

s*****n
发帖数: 741

来自主题: Macromolecules版 - 请教：peptoid 这个东西是高分子吗

老板最近想做一个peptiod方面的课题，不仅是合成，我就是想全面但是想快速的了解
一下，不知道给我前辈牛人们能不能推荐一些经典的书或者文章给我。感激不尽。

P********n
发帖数: 372

来自主题: Macromolecules版 - 请教：peptoid 这个东西是高分子吗

类似peptide的东西吧。我觉得不应该归到高分子里。

m*********k
发帖数: 10521

来自主题: _mitbbscheck版 - 2010 0810 首页文章奖励

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