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全部话题 - 话题: pgc1
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t*d
发帖数: 1290
1
真是有钱人会更有钱
Exercise benefits a variety of organ systems in mammals, and some of the
best-recognized effects of exercise on muscle are mediated by the
transcriptional co-activator PPAR-γ co-activator-1 α (PGC1-α). Here we
show in mouse that PGC1-α expression in muscle stimulates an increase in
expression of FNDC5, a membrane protein that is cleaved and secreted as a
newly identified hormone, irisin. Irisin acts on white adipose cells in
culture and in vivo to stimulate UCP1 expression and a broad ... 阅读全帖
l****b
发帖数: 400
2
来自主题: Biology版 - Nature: 一针FGF1治疗糖尿病
I can’t type Chinese at work, so bear with me for the use of English.
1) Make no mistake, my friend. I am no Evans’ fan. And exercise mimetic
is not his idea. We are here to discuss science, not personal belief.
2) Exercise mimetic is just an example. Do you know what an example is?
That doesn’t mean that I believe in it. But certainly not having too many
follow-ups or not having a drug on the market with this mechanism of action
is not evidence to say that it doesn’t work. We have not suc... 阅读全帖
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