h***y
发帖数: 834 | 1 关于dilantin，刚去看了一下pfizer的网页：
Unusually high levels result from liver disease, congenital enzyme
deficiency, or drug interactions which result in metabolic interference. The
patient with large variations in phenytoin plasma levels, despite standard
doses, presents a difficult clinical problem. Serum level determinations in
such patients may be particularly helpful. As phenytoin is highly protein
bound, free phenytoin levels may be altered in patients whose protein
binding characteristics differ fr... 阅读全帖 |
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J*********4
发帖数: 1274 | 2 The answer should be phenytoin, not amiodarone. Check UW again. Phenytoin
induced P450 enzymes |
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f****o
发帖数: 2770 | 3 The treatment of choice depends on the type of epilepsy (Table 50-2) and on
drug-specific adverse effects and patient preferences. Figure 50-1 is a
suggested algorithm for treatment of epilepsy.
Begin with monotherapy; about 50% to 70% of patients can be maintained on
one antiepileptic drug (AED), but all are not seizure free.
Up to 60% of patients with epilepsy are noncompliant, and this is the most
common reason for treatment failure.
Drug therapy may not be indicated in patients who have had ... 阅读全帖 |
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f****o
发帖数: 2770 | 4 该是可以确
诊了，小孩昨晚又发作了几次，并且小孩能够意识到，到发作时候就自己醒了）
NO, I do NOT have license/credential to diagnose, I am not a physician,
I'm a pharmacist. I can only answer drug-related questions. And, even if
I am a Physician, it is difficult to diagnose someone on the internet
without seeing the actual patient.
和
Alternative Drugs，它们都是适用于partical seizure吗？还是partial seizure下面有
很多子类型，每个子类型分别对应一种first-line drugs 和alternative Drugs。不好意
思，没有看明白，麻烦你有空时解释一下。
I copy and pasted these from other reference: pharmacotherapy poc... 阅读全帖 |
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A*****a
发帖数: 52743 | 5 Antiviral drugs
Cases of encephalitis due to certain viruses usually require intravenous
antiviral treatments. Antiviral drugs commonly used to treat encephalitis
include:
Acyclovir (Zovirax)
Ganciclovir (Cytovene)
Foscarnet (Foscavir)
Some viruses, such as insect-borne viruses, don't respond to these
treatments. However, because the specific virus may not be identified
immediately or at all, treatment with acyclovir is often begun immediately.
This drug can be effective against the herpes simpl... 阅读全帖 |
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u***e
发帖数: 611 | 6 癫痫的治疗没有什么大的进展，还是用那些药物，什么phenytoin, valproic acid之类
的，美国也没什么先进的办法。我看那些癫痫的病人不发病的时候也都活得和正常人一
样，看不出什么明显的副作用。会导致人格障碍没有听说过。能用单药控制就用单药，
不要一上来就一堆药上去。有些病人一来,on dilantin,depakote,keppra.....还在
seizing,神啊。 |
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s******v
发帖数: 477 | 7 Why use brand names in prescriptions? What if I wrote Lorazepam instead of
ativan, phenytoin instead of Dilantin? It is hard to new interns to remember
all the names of medications. |
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k**********n
发帖数: 438 | 8 还没啥感觉呢，这个月elective，本来就不用早起。不过欠了一些债，被人追打，日子
也不很好过:) I guess it does not matter either you write lorazepam/ativan or
Dilantin/Phenytoin, pharmacy has to verify it anyway. |
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l********y
发帖数: 2295 | 9 这个step1和step2都很爱考，希望自己考试的时候还能记住：
induction of P-450: 这个大家都知道吧，不知道的面壁。
Queen Barb Refuse Phen Sit Gray Car.
Inhibition of P-450: 不知道的面壁。
Inhibitors Stop Crying Kids from Eating Grapefruit.
Metabolsim by P-450:
话说阿Q被大赦，幸运的娶了茶宝宝，可是还是三天两头的吵架，pony就劝他别吵啦，
拍拍MP气就消了，就被450给代谢啦。
阿Q（AQ），No War,Please MP 茶 BB。
A:amide anesthetics
Q: quinidine
N: nifedipine
War: warfarin
P：Phenytoin
M: metoprolol
P: propranolol
茶：theophylline
B: benzodiazepines
B: barrbiturates |
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H*****1
发帖数: 41 | 10 a 72-year-old female is brought to the ER with severe shortness of breath,
tachypnea and pleuritic-type chest pain. she had a similar episode 2 months
ago and has been treated with warfarin since the. she says that she has been
compliant with her medications. her PT is found to be sub-therapeutic.
which of the following concurrent medications is most likely taking?
a) aspirin
b) phenylbutazone
c) oxycodone
d) acetaminophen
e) metronidazole
f) cimetidine
g) phenytoin
h) amiodarone
i) diazepam
ans... 阅读全帖 |
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e****0
发帖数: 678 | 11 Endometrial hyperplasia types. Risk of cancer treatment
simple 1% Cyclic progestin
complex 3% Cyclic progestin
Simple atypical 8% THA or progestins
Complex atypical 29% THA or progestins
• Prolatinoma and hypothyroidism galactorrhea
• Anesthesia can reduce uterine activity if in the latent phase
• Contraceptive for lactating mother
Progestin-only oral contraceptive
• Pregnancy luteoma
African-ameri... 阅读全帖 |
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r*******n
发帖数: 135 | 13 正在盯着这些难点发呆。 有没有人(Jeff?)能不能把“宫女的故事”、“帮人大哥，帮
人二哥和胖大妈的故事”、“比武大赛”、“奥巴马的二姨”跟贴分享以下，或者PM给
我吖？或者R*********[email protected] 我已经有那几个Pdf(韦小宝NF1 and NF2、
Phenytoin、Trastuzumab (Herceptin)等)
正在仔细地啃啊啃：
好Amazing!
http://www.mitbbs.com/article_t/MedicalCareer/31496831.html
谢谢Jeff分享．非常有用！！真是太有才的奇葩啊！！！！
－－－－－－－
用“宫女的故事”把collagen 合成的每个细节都搞定；用“帮人大哥，帮人二哥和胖
大妈的故事”把Th1, Th2, Macrophage所分泌的cytokines和各自功能都一网打尽；用
“比武大赛”来记耐药菌的抗生素治疗；用“奥巴马的二姨”来记tissue nematodes的
特点（刚好我的考试里考了其中一个知识点，不用巧办法是很难记住的）。
预先谢谢了！！ |
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z******8
发帖数: 844 | 16 ☆─────────────────────────────────────☆
zhu84518 (Henry) 于 (Mon May 5 23:08:37 2014, 美东) 提到:
一个好的口诀胜读10遍书，记住的知识点那是经久不忘，真是受益匪浅。我和Jeff一起
学习的时候编了不少好的口诀，现在Jeff考试考完了，match完了，抽点时间和我一起
把我们之前的口诀总结出来，一来是奉献麦地，也希望能够帮助后来的同学，二来是防
止我们的口诀继续在那里吃灰，这可都是我们耗费了多少脑细胞的成果。我们打算每天
抽点时间把口诀贴到此贴，如果有同学有自己的口诀想要分享，欢迎跟帖！
☆─────────────────────────────────────☆
zhu84518 (Henry) 于 (Mon May 5 23:12:40 2014, 美东) 提到:
☆─────────────────────────────────────☆
zhu84518 (Henry) 于 (Mon May 5 23:19:23 2014, 美东) 提到:
Toxopl... 阅读全帖 |
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y******7
发帖数: 17 | 17 The following is what I collected when I was a student doing capstone in a
local hospital. Not sure if it is useful.
Lidocaine topical is a amide-type local anesthetic. for production of
topical anesthesia, relief of pain associated with postherpetic neuralgia,
reduction of gagging during dental procedures, prevention and control of
urethral pain, anesthetic lubricant for endotracheal intubation, and relief
of hemorrhoidal pain.
Polyethylene glycol(Miralax) is a nonabsorbed solution used to trea... 阅读全帖 |
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c********y
发帖数: 33 | 18 准备第一步evaluation exam总结的，都是参考别的书的，也不是很全面，所以如果有
错误请多包
涵，如下：
Methyldopa —— galatorrhea, SLE
Levodopa - taste disturbance
Procainamide - SLE, agranulocytosis,torsade de points
Captopril - agranulocytosis
ACEI - taste disturbance, dark stool
Cyclosporin - acute gout, gingival overgrowth
Phenytoin - SLE, gingival overgrowth
Thiazide - SLE, pulmonary edema, gout
Sulfasalazine - Pulmonary fibrosis, SLE
Chlopramazine - SLE, seizure, dry mouth
Verapamil - galactorrhea, bradycardia
PTU - agranulocytosis, S... 阅读全帖 |
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f****o
发帖数: 2770 | 19 复习时间：2.5 weeks
复习材料：protonpass, APhA book, miscellaneous
感觉：考下来感觉难度一般。个别问题觉得没有正确答案，个别问题完全不知道怎么答
。大部分问题还是有底的。
考的范围很广，我的考卷涉及到的题目有：
math 10%(网上有人说会占30%,可能他们错太多，所以naplex系统给他们题目直到做对
为止吧), prescription evaluation, compounding, kinetics, biostatics, heart
failure, arrhythmia, hypertension, anticoagulation, lipids, diabetes,
endocrine, women's health, ADHD, asthma/COPD, ESRD, seizure, oncology
supportive care, basic HIV, opportunitic infection, ID, lots of IDs,
nutrition, electrolytes, gout, GI, pain, p... 阅读全帖 |
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b**o
发帖数: 5769 | 20 ☆─────────────────────────────────────☆
fiorio (那朵花~一定还在某个地方盛开着~) 于 (Sun Jul 8 01:26:21 2012, 美东) 提到:
复习时间：2.5 weeks
复习材料：protonpass, APhA book, miscellaneous
感觉：考下来感觉难度一般。个别问题觉得没有正确答案，个别问题完全不知道怎么答
。大部分问题还是有底的。
考的范围很广，我的考卷涉及到的题目有：
math 10%(网上有人说会占30%,可能他们错太多，所以naplex系统给他们题目直到做对
为止吧), prescription evaluation, compounding, kinetics, biostatics, heart
failure, arrhythmia, hypertension, anticoagulation, lipids, diabetes,
endocrine, women's health, ADHD, asthma/COPD, ESRD, seizure, oncology
sup... 阅读全帖 |
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m**s
发帖数: 520 | 21 An acronym for memorizing Class 1 agents:
IA - Double Quarter Pounder (Disopyramide, Quinidine, Procainamide)
IB - Mayo Lettuce Tomato Pickles (Mexiletine, Lidocaine, Tocainide,
Phenytoin)
IC - More Fries Please (Moricizine, Flecainide, Propafenone) |
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c****m
发帖数: 626 | 22 ann2008
看很多人问这个考的多不多，那个多不多，每个人的考试侧重点会完全不一样，fioro&
#8232;计算和药物反应不多，不代表你不会被考到。我的计算就很多，也不代表你错的
多，如
果看bulletin,计算的比例就很高，而且好几道TPN的。主要作为一个参
考，而不是复习
的指南。我还被考到几题一样的，我确定我答的是对的，所以
也不要freak out。
我的最后也有profile的题目。
HIV也被考到了
brand 和generic，所以什么都可能考，不过NAPLEX就是一个minimum
competency的考试，大家肯定没问题的。
PhDPharmD
刚刚查了naplex分数，过了，分数居然还不错。 考完觉得要fail了。我的考题是rare
diseases，rare drug names and dosage forms 占据的了整个考试。其他的常
见的东
西也都有，但是都是蜻蜓点水的考一下，一两题的样子。计算也不多。
虽然我没好好复
习，只是看了常见的内容，但... 阅读全帖 |
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y*****l
发帖数: 5997 | 23 sppi 最近要炒FDA吗？
Spectrum Pharmaceuticals Responds to FDA's Complete Response Letter for
Fusilev
Sunday 11/07/2010 1:04 AM ET - Close-up Media
Spectrum Pharmaceuticals, a biotechnology company with fully integrated
commercial and drug development operations with a primary focus in oncology,
announced that on Friday, October 29, it submitted a complete response to
the "Complete Response" letter issued by the U.S. Food and Drug
Administration (FDA), regarding its supplemental New Drug Application (s... 阅读全帖 |
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v**********m
发帖数: 5516 | 24 来自主题: _pennystock版 - sppi http://www.businesswire.com/news/home/20110421006626/en/Spectru
April 21, 2011 02:42 PM Eastern Daylight Time
Spectrum Pharmaceuticals Announces FDA Approval of FUSILEV®’s Ready-to
-Use Formulation (RTU)
* Until Now FUSILEV® Has Been Available Only As A Lyophilized
Product
* FUSILEV® sNDA For Use In Advanced Metastatic Colorectal Cancer is
Currently Under Review By The FDA
o PDUFA Action Date – April 29, 2011
* FUSILEV® Is Currently FDA Approved and Mark... 阅读全帖 |
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