c*9 发帖数: 3241 | 1 From: "wq" View Contact Details Add Mobile Alert
Subject: Re: I am back and need your contact info
To: "Hanlin Li" , r******[email protected], "Jin Ya" <
j*******[email protected]>, "sun wei"
Date: Mon, 12 Dec 2005 13:35:20 +0800
so glad to hear from u from shanghai.
my cell: 13600072567
PF: 13570066776
contact u later, see u.
On Sat, 10 Dec 2005 18:06:27 -0800 (PST)
Hanlin Li wrote:
> Dear piglets,
>
> I am back in China. It... 阅读全帖 |
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i*****s 发帖数: 4596 | 2 有一个不怎么准确的译文,不过可读性倒是不低,我把原文附在后面:
祖神来归式科学
费曼(Richard Feynman)
在中世纪,有各种类型的古怪观念,如象一块犀牛角会增强权力。后来找到一种方
法将各种观念进行分类 --- 行得通就弄明白它,行不通就取消它。尔后,这种方法
就逐步形成科学。而且它发展得很好,所以我们现在是处在科学的时代。然而使我
们很难理解的是,就在这样一个科学时代巫医怎么会存在,巫医提出的事,从没有
真正行得通 --- 或者很少行得通。
但是时至今日,我遇到不少人,他们总会和我说到飞碟(UFO),或者星相学,或者
某些神秘主义,扩大的知觉,新型意识,超感觉力,等等。我得到结论,这都不属
于科学世界。
许多人相信那些荒诞不经的事物,使得我决意研究他们为什么这样。我的好奇心促
使我去进行研究,而所涉及到的内容却使我陷入困境。居然有这么多糟粕,真使人
吃惊。首先我由研究神秘主义,神秘经验的各种思想入手。我进到隔离的试验槽,
并有过许多小时的幻觉经历,所以我知道关于神秘主义的某些东西。我还去过埃萨
伦,这里是各种思想的温床(这是一个很好的地方,你们应当去看看)。然后我变
得不... 阅读全帖 |
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y*z 发帖数: 3244 | 3 The Hague, 12 July 2016
The Tribunal Renders Its Award
A unanimous Award has been issued today by the Tribunal constituted under
Annex VII to the United Nations Convention on the Law of the Sea (the “
Convention”) in the arbitration instituted by the Republic of the
Philippines against the People’s Republic of China.
This arbitration concerned the role of historic rights and the source of
maritime entitlements in the South China Sea, the status of certain maritime
features and the maritime enti... 阅读全帖 |
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C****U 发帖数: 994 | 4 (非正式翻译)
南海仲裁案
(菲律宾共和国 v. 中华人民共和国)
海牙,2016年7月12日
仲裁庭发布裁决
今日,根据《联合国海洋法公约》(“《公约》”)附件七组成的仲裁庭就菲律宾共和国
对中华人民共和国提起的仲裁案作出了一致裁决。
该仲裁案涉及在南海的历史性权利的作用和海洋权利的渊源、某些岛礁的地位及其能够
产生的海洋权利,以及菲律宾声称违反了《公约》的中国某些行为的合法性问题。考虑
到《公约》对强制争端解决的限制性规定,仲裁庭强调,它既不对任何涉及陆地领土主
权的问题进行裁决,也不划定当事双方之间的任何边界。
中国反复申明“其不接受、不参与由菲律宾单方面提起的仲裁”。然而,《公约》附件
七规定,“争端一方缺席或不对案件进行辩护,应不妨碍程序的进行”。附件七同时规
定,在争端一方不参与程序的情况下,仲裁庭“必须不但查明对该争端确有管辖权,而
且查明所提要求在事实上和法庭上均确有根据”。因此,在整个程序中,仲裁庭采取了
一些步骤验证菲律宾诉求的正确性,包括要求菲律宾提交进一步的书面论证,在两次庭
审之前及庭审过程中对菲律宾进行询问,指定独立的专家就技术性问题向仲裁庭报告,
以及获取... 阅读全帖 |
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s******r 发帖数: 5309 | 5 New York files suit against President Trump, alleging his charity engaged in
‘illegal conduct’
2:26
How Donald Trump directed millions to his foundation
Donald Trump directed millions of dollars to his tax-exempt foundation. Here
's how. (Video: Peter Stevenson, Lee Powell/Photo: Jabin Botsford/The
Washington Post)
By David A. Fahrenthold
June 14 at 11:19 AM
Email the author
The New York attorney general on Thursday filed suit against President Trump
and his three eldest children alleging “persi... 阅读全帖 |
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z**********e 发帖数: 22064 | 6 二战中美国兵因为这个被打死的很多,美国兵对这个怨声载道。
还有,这个跟人多人少有关系吗?
其实,就是拉枪栓的声音,都不这么危险:至少它不告诉对方,我没子弹了。
查到了这个,在韩战中,美军采用“双枪制”:两人配合,一个打,一个压满子弹等着
;等到“砰”一声弹夹弹出,对方露头时,压满子弹的那个就正好开火。
http://thefiringline.com/forums/archive/index.php?t-106892.html
PDAView Full Version : Did the Garand`s "ping" get GIs killed?
----------------------------------------------------------------------------
----
FatelvisMarch 28, 2002, 07:51 PM
I once heard, that in close-up fighting, (I believe in the South Pacific),
that in a stalemate cover situa... 阅读全帖 |
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l****z 发帖数: 29846 | 7 by Robert Farley
In press conferences on the so-called fiscal cliff, House Speaker John
Boehner greatly exaggerated the negative effect on the economy of raising
taxes on upper-income individuals.
Boehner erred when he said that “the problem with raising tax rates on
the wealthiest Americans is that more than half of them are small-business
owners.” That’s incorrect. Boehner’s spokesman said the speaker simply
misspoke, but Boehner is a repeat offender with this bogus claim.
Boehner repe... 阅读全帖 |
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l****z 发帖数: 29846 | 8 Obama: Pulling All U.S. Troops Out of Iraq Was Not ‘My Decision'
August 9, 2014 - 8:37 PM
By Terence P. Jeffrey
(CNSNews.com) - When he was running for re-election in 2012, President
Barack Obama repeatedly took credit for ending the war in Iraq and bringing
all U.S. troops home from that country. Today, at the White House, however,
when talking about his decision to use military force against the al-Qaida-
related ISIS terrorist group in Iraq, Obama said that removing all U.S.
troops from Iraq ... 阅读全帖 |
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x****o 发帖数: 21566 | 9 我还以为是
"I do not repeat myself. I do not repeat myself. No, no, you repeat. You
repeat. You repeat yourself. " -- Donald Trump |
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S**I 发帖数: 15689 | 10 ☆─────────────────────────────────────☆
gzou (gzou) 于 (Thu May 12 02:26:35 2011, 美东) 提到:
马上就要G on site了,
求祝福。
下面是从本版收集到的Google的试题,便于大家查询。
申明:有的附带有解释说明的,也来自于本版或者网络,大家自己看, 不保证真确
http://www.mitbbs.com/article_t1/JobHunting/31847453_0_1.html
本人ECE fresh PhD,背景是电路/EDA,跟G业务基本没什么关系
同学内部推荐的,很简单的一次电面就给了onsite
题都不难,但是自己没把握好机会,出了一些小bug。
总的感觉,出错就是硬伤,宁可从最简单的算法写起,也不能出错。
电面:
1,Skip list, http://en.wikipedia.org/wiki/Skip_list
写code实现struct skip_list * find(struct skip_list *head, int value)
2,sorted array... 阅读全帖 |
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S**I 发帖数: 15689 | 11 ☆─────────────────────────────────────☆
gzou (gzou) 于 (Thu May 12 02:26:35 2011, 美东) 提到:
马上就要G on site了,
求祝福。
下面是从本版收集到的Google的试题,便于大家查询。
申明:有的附带有解释说明的,也来自于本版或者网络,大家自己看, 不保证真确
http://www.mitbbs.com/article_t1/JobHunting/31847453_0_1.html
本人ECE fresh PhD,背景是电路/EDA,跟G业务基本没什么关系
同学内部推荐的,很简单的一次电面就给了onsite
题都不难,但是自己没把握好机会,出了一些小bug。
总的感觉,出错就是硬伤,宁可从最简单的算法写起,也不能出错。
电面:
1,Skip list, http://en.wikipedia.org/wiki/Skip_list
写code实现struct skip_list * find(struct skip_list *head, int value)
2,sorted array... 阅读全帖 |
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b*****9 发帖数: 8922 | 12 ☆─────────────────────────────────────☆
hehehahahehe (hehehahahehe) 于 (Sun Aug 15 14:32:47 2010, 美东) 提到:
自然环境,自然不必说。
就是不喜欢国内的社会,经济,文化,政治等环境,也不想让小孩接触那样的环境。--
-无论国内发展的有多好, 有多快。
所以就不归。道理就这么简单。
另外,国内信息太封闭。你根本无法从多种渠道来了解一件事情的真相,因为无论任何
事情都只有一种声音,一种报道。
再有,这个论坛很多人写的回国有多好的所谓“经历”,我觉着有些是真的,有些是编造出来的,这些编出来的"回国经历"是用来忽悠人回国工作的的。
特别是那些人还在国内的人写的“经历”,更是不可相信。因为这个论坛在国内根本就上不去。原来的mitbbs.cn还能上,后来这个.cn结尾的取消了.mitbbs.com在国内根本上不去,怎么能跑到这里写和发表所谓“回国经历”呢?
更何况,国外,特别是发达国家,对平头老百姓的保护更好。我觉着对于大部分人,就想当个平头老百姓,过好自己的生活就是了,根本不会去争取什么“... 阅读全帖 |
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b*****9 发帖数: 8922 | 13 ☆─────────────────────────────────────☆
lightness (轻) 于 (Mon Aug 16 16:21:12 2010, 美东) 提到:
他做啥的在国内会有限制,美国反而没限制?
☆─────────────────────────────────────☆
xiaoshuai (小帅) 于 (Mon Aug 16 16:28:50 2010, 美东) 提到:
兄弟我西城区户口,还不是出来了。
都是浮云/
☆─────────────────────────────────────☆
shakespear (fluke) 于 (Mon Aug 16 16:29:08 2010, 美东) 提到:
他做啥的在国内会有限制,美国反而没限制?
倒卖军火?
传播基督教?
做持不同政见人士骂共产党?
☆─────────────────────────────────────☆
cyberz (cyberz) 于 (Mon Aug 16 16:32:05 2010, 美东) 提到:
赞“在北京有房,家庭年收入税后6... 阅读全帖 |
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b*****9 发帖数: 8922 | 14 ☆─────────────────────────────────────☆
Manto (馒头) 于 (Mon Aug 16 19:36:59 2010, 美东) 提到:
既然这儿已经变油盐酱醋版了,借人气问问。
我最爱吃我妈做的炒牛蛙,每次我回去她会去农贸市场买活牛蛙,小贩砍头扒皮切成块
儿拿回家肉块儿还在抽搐,下火一炒,倒口五粮液,那叫一个美呀(口水流一键盘)。
在美国去哪儿买活牛蛙?别告诉我自己逮去啊。
☆─────────────────────────────────────☆
repeating (randomly) 于 (Mon Aug 16 19:38:34 2010, 美东) 提到:
三藩市。在美国除了没有卖狗肉的,其他都有。
☆─────────────────────────────────────☆
Manto (馒头) 于 (Mon Aug 16 19:40:44 2010, 美东) 提到:
早知道当初工作应该找到三藩去
☆─────────────────────────────────────☆
repeating ... 阅读全帖 |
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c*******o 发帖数: 27734 | 15 ☆─────────────────────────────────────☆
mikef (mike) 于 (Tue Jun 7 00:23:49 2011, 美东) 提到:
这几天钻研了下最近10年中国的房地产行情,
这个世界上不知还有哪个国家,人民有这么愚蠢和爱跟风。
平均拿着5万-10万的年薪,天天钻营着要买100-300万的房子
而更加荒谬的是,垃圾地方政府和房地产商竟然真的也真敢把房子价格一次次地哄抬到
到数百万上。--中央政府的宏观调控以及法制真是糟糕混乱到了极点。
大部分政府官员和房地产商是投机倒把、狼狈为奸,脑子没病心理有病,
老百姓是心理没病,脑子被忽悠的有病
这真是一个奇怪的国家,处在一个怪异的状态。
肯定哪里不健康,但它耀武扬威的高速增长的GDP又似乎遮掩住了所有丑陋。
不归了,还是到加拿大去做FACULTY吧。
一家15万刀年薪过几年买个40万刀的房子,清净地安享生活吧
海归国内,买个200万的房子,就等于把一辈子卖给国家做苦力而不能翻身了。
生活,你至少得合理吧?如果社会不给你合理的待遇和生活,归个屁啊
☆────────────────────... 阅读全帖 |
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a*******t 发帖数: 1886 | 16 Symptoms
By Mayo Clinic Staff
Obsessive-compulsive disorder symptoms usually include both obsessions and
compulsions. But it's also possible to have only obsession symptoms or only
compulsion symptoms. About one-third of people with OCD also have a disorder
that includes sudden, brief, intermittent movements or sounds (tics).
Obsession symptoms
OCD obsessions are repeated, persistent and unwanted urges or images that
cause distress or anxiety. You might try to get rid of them by performing a
com... 阅读全帖 |
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C**********y 发帖数: 480 | 17 看这篇文章:
http://www.newyorker.com/magazine/2014/09/01/friends-israel
有点长,一句话总结:胡萝卜加大棒,各议员的竞选经费10~15%来自犹太人,不听话
,下次对手会拿到这钱,差额就是20到30%!
This was a daunting challenge. Jews made up less than three per cent of the
American population, concentrated in nine states, and they voted
overwhelmingly Democratic. How could AIPAC, with such a small base, become a
political force in both parties and in every state?
Dine launched a grass-roots campaign, sending young staff members around the
country to search for ... 阅读全帖 |
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i********c 发帖数: 7033 | 18 到2014-2015年,开始征收repeater奢侈税,就是说,如果前3年都在交奢侈税的话
,就算你是repeater,税率更高。(谁能告诉我,今年的ny交奢侈税了吗? )
今年奢侈税线 70.3M, 初步假设2014年奢侈税线 75M ;
NY到2014年,3巨头的合同 62.4 M ,加上林的9.3 M + KID的3M ; 这5个人工资就
要74.7M了。 球队至少要13人,还要签8人,按人均1.2M吧,就是 8x1.2 = 9.6 M; (
这里没有算任何的mini中产,特例了)
这样的话,工资总额 74.7 + 9.6 = 84.3 M , 超过假定cap 9.3M ;
1) 这里,比较关键的是,如果真能控制在 5M-9.9M之间,税率是1.75(repeater的
话2.75) ;
2)但是,我前面算的是最保守的了,连香波,道格拉斯之类的,我都没放进去,所
以,比较大的可能是,超过cap 10M -15M吧,此区间税率2.5 (repeater 是3.5) ;
要我估计,2014年的Ny可能 交税 12.5 x 2.5 = 31... 阅读全帖 |
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k**********i 发帖数: 8706 | 19 搬板凳坐等matlab和c/++/#版
好吧
我抛砖引玉,来个苹果机logo语言小海龟版
REPEAT 360 [FD 5 RT 1]
END
LT 90
FD 5
REPEAT 360 [FD 10 RT 1]
END
FD 5
REPEAT 360 [FD 15 RT 1]
END
FD 5
REPEAT 360 [FD 20 RT 1]
END
FD 5
REPEAT 360 [FD 25 RT 1]
END
....貌似不是同心圆。。。 |
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i**r 发帖数: 998 | 20 1). Why the delay in reporting Tressel's violations?
It was crystal clear on Jan. 13 that Tressel had knowingly played ineligible
players throughout the 2010 season, but Enforcement wasn't notified for
nearly three weeks, until Feb. 3, the day after National Signing Day.
2). Do you want to be affiliated with someone like Tressel?
Ohio State makes the case in its response to the NCAA Notice of Allegations
that it suffered a serious penalty by taking "decisive action against a very
successful coac... 阅读全帖 |
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m*e 发帖数: 1018 | 21 一个月前从楼梯上左脚滑了一跤,接着打了一场球后,左脚跟有些疼,没太在意,以为
慢慢可以恢复,可一个月过去了,才好了六成的样子,单左脚尖可以把自己顶起来但很
吃力。今天仔佃查了下,应该是跟腱炎achilles tendon;期间还是一直在练球,休息
不够,变成像网球肘一样的毛病了。悲惨啊,接下来打球不能跑不能跳了。。。
贴个link,以后网球新人们参考。
http://www.itftennis.com/scienceandmedicine/injury-clinic/tenni
Achilles Tendon
Diagnosis
An injury of the Achilles tendon is a degenerative condition of the tendon,
not an inflammatory process. It is therefore incorrect to describe this as
tendinitis. Tendinopathy is a better term.
The injury is caused by chronic repeti... 阅读全帖 |
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M******e 发帖数: 60 | 22 You can try this. It is for lower back pain.
Pelvic tilts: lie on the back with the legs bent and feet hip distance apart
. Inhale -- press the tailbone down creating a small arch in the back,
exhale -- press the small of the back down pressing it to the floor and
tilting the tailbone a little bit up. Repeat 4-6 times.
Apanasana -- bring the knees to the chest and place the hands on the knees
fingers pointing forward. Inhale -- press the knees away from you, exhale --
bring the knees closer leng... 阅读全帖 |
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j******n 发帖数: 21641 | 23 与这个画有关的趣事有很多
转一段, 你有耐心可以把它读完, 否则等clam来读, 他喜欢这口
This famous painting has become an icon of the Puritan strain in America.
The poems below hardly need any commentary. Both of them are essentially
humorous; both point out the echoes contained in the painting; both get
inside the minds of the models, making us see the process of posing (and by
extension, the painting itself) as somewhat absurd rather than solemn.
AMERICAN GOTHIC
Just outside the frame
there has to be a dog
chickens, cows and hay
and... 阅读全帖 |
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V***x 发帖数: 7626 | 25 2.歌曲上传wenxuecity 再用flashplayer 播放的步骤:
2.1 http://web.wenxuecity.com/upload.php
如果你没有文学城笔名的话,注册一个先。:)
这个步骤目的是:
a.如果您只想上传您的歌曲音乐取得一个连接而不想直接上传并发贴,请在此上传,上传
之后系统会将您的歌曲音乐连接直接发送到您的悄悄话里,留着日后使用.
b.从悄悄话里获得歌曲链接后,为贴mitbbs备用
2.2 假设你得到的歌曲链接是:
http://space.wenxuecity.com/media/1302970298.mp3
你可以做如下举动:
在歌曲链接前加上vhttp://www.longtailvideo.com//files/player.swf?screencolor=ffffff&controlbarsize=80&repeat=1&file=
得到:
【vhttp://www.longtailvideo.com//files/player.swf?screencolor=ffffff& controlbarsize=80&repeat=1&file=... 阅读全帖 |
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V***x 发帖数: 7626 | 26 嗯,继续转帖置顶文章:)
“歌曲上传wenxuecity 再用flashplayer 播放的步骤:
2.1 http://web.wenxuecity.com/upload.php
如果你没有文学城笔名的话,注册一个先。:)
这个步骤目的是:
a.如果您只想上传您的歌曲音乐取得一个连接而不想直接上传并发贴,请在此上传,上传
之后系统会将您的歌曲音乐连接直接发送到您的悄悄话里,留着日后使用.
b.从悄悄话里获得歌曲链接后,为贴mitbbs备用
2.2 假设你得到的歌曲链接是:
http://space.wenxuecity.com/media/1302970298.mp3
你可以做如下举动:
在歌曲链接前加上vhttp://www.longtailvideo.com//files/player.swf?screencolor=ffffff&controlbarsize=80&repeat=1&file=
得到:
【vhttp://www.longtailvideo.com//files/player.swf?screencolor=ffffff& controlbarsize=80&re... 阅读全帖 |
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p******s 发帖数: 938 | 27 Sting给杀手里昂配的片尾曲,词曲精彩深刻不说,那原声吉它的演
奏实在是精彩之极。在网上找到几个版本大家看看:
Shape Of My Heart - transcribed by Luis Ferreira
This is NOT the way Dominic Miller plays it. I've got Sting's concert in Oslo
(1994) in videocassette and it is definitely harder than this. Dominic Miller
uses an electric-shaped acoustic guitar, which makes it easier to play in the
high frets as he does. The names of the chords might not be correct, too.
( If you want to play with the record, then use a capo on the 2nd fret )
Intro:
... 阅读全帖 |
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f********1 发帖数: 698 | 28 Thank you very much! This is exactly what I'm looking for in this thread. I
agree with you that imatation is always the best way to learn a foreign
language. Once appealling but now demonized, Yi Yang Crazy English was a
good strategy -I did make some progress in oral English by following his
theory of "exercising your English muscles by repeat imatation". This kind
of practice came to a pause when I came to the states several years ago
simply because I thought it was silly enough to practice En... 阅读全帖 |
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y****g 发帖数: 36950 | 29
这是整个playlist的repeat,很多播放器按住那个repeat会有单曲repeat和整个
playlist repeat模式切换。就是说你听到一个play list里某首歌想多听几遍,选择单
曲repeat就会重复那一首歌曲。我在media player里找不到这个模式,明白么? |
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f**********r 发帖数: 18251 | 30 【 以下文字转载自 Military 讨论区 】
发信人: TempBM (Temp), 信区: Military
标 题: 2013年军版名人榜颁奖盛典
发信站: BBS 未名空间站 (Tue Jun 3 23:12:37 2014, 美东)
2013年军版名人榜之十大著名ID
dsb
qwxqwsean
kayaker
stoppingtime
wayofflying
choming
hairi
xiaxie8
closingbell
cynic
2013年军版名人榜之十大语言艺术大师
kayaker
qwxqwsean
dsb
hairi
stoppingtime
coho
xiaxie8
repeating
choming
closingbell
2013年军版名人榜之十大优秀评论员
dsb
kayaker
hairi
pacific
stoppingtime
choming
THR
wayofflying
qwxqwsean
repeating
------------------------------
投票结果:
2013年军版名人榜之十大著名ID
http://ww... 阅读全帖 |
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a***y 发帖数: 19743 | 31 和最开始Shuffle的很像。不过是Microsoft做的。
http://www.syncmyride.com/Own/Modules/SupportContent/UsingSyncSupport.aspx?hdi=10
"Play" tells SYNC to begin playing at the beginning of the file or at the
place where playing last stopped.
"Play all" instructs SYNC to play all the music on the media player.
If you have already selected an artist, album, genre, or similar music, Play
All instructs SYNC to play all the music in the chosen section, such as all
the tracks by the chosen artist, all the songs on a selec... 阅读全帖 |
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k**********i 发帖数: 8706 | 32 【 以下文字转载自 GunsAndGears 讨论区 】
发信人: kelvinchufei (Kelvin), 信区: GunsAndGears
标 题: Re: 写了个生成练习的纸靶子的程序
发信站: BBS 未名空间站 (Wed Dec 29 22:00:55 2010, 美东)
搬板凳坐等matlab和c/++/#版
好吧
我抛砖引玉,来个苹果机logo语言小海龟版
REPEAT 360 [FD 5 RT 1]
END
LT 90
FD 5
REPEAT 360 [FD 10 RT 1]
END
FD 5
REPEAT 360 [FD 15 RT 1]
END
FD 5
REPEAT 360 [FD 20 RT 1]
END
FD 5
REPEAT 360 [FD 25 RT 1]
END
....貌似不是同心圆。。。 |
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发帖数: 1 | 33 最近genotype一个cancer cell line(neuroblastoma)的microsatellite (tandem
repeat)位点
大概三个月前测的是这个位点是homozygous有6个repeat
然后最近重新解冻另外一个stock,start cell culture,测量同样的位点,居然成了
heterozygous,一半仍然6个repeat,另外一半成了10个repeat;反复做了很多遍,换
了所有的reagent生怕是contamination,但结果还是一样。
问了lab technitian,这个neuroblastoma在我们实验室都是一样的来源,他也怀疑这
个repeat是不是dynamics的
三个月前的cell line的passage不记得了
最近这个cell line的passage大概是p10
我想问下,cancer cell line的genome microsatellite难道真的会传代传着传着就发
生了变化?如此不稳定? |
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y*******1 发帖数: 164 | 34 如果这个repeat是300bp,而测序用的100x2 PE
那可能align之后,default的输出结果可能有几种情况
1)两个read都在repeat区域,那每个read都会输出排名靠前的几个alignment,无法确
认具体是genome里哪个repeat
2)其中一个read能map到repeat边缘的unique区域,那么这个read能输出unique
alignment。另外一个read输出排名靠前的几个alignment,这个可以通过自己写的小脚
本只选择离unique mapped read最近的那个alignment。
3)两个read都是map到unique区域,这个就没有问题了。
根据上面的几种情况,虽然能得到一些uniquely mapped的read,但是也只是这个
repeat附近ChIP的部分信息,还是不能准确估算ChIP的信号强弱。 |
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发帖数: 1 | 35 Alu属于sine,是散在重复序列,如果片段长度也是300,刚好落在一个元件内部的概率
很低吧,也就是情况2比较多,还是能得到一些信息的。
: 如果这个repeat是300bp,而测序用的100x2 PE
: 那可能align之后,default的输出结果可能有几种情况
: 1)两个read都在repeat区域,那每个read都会输出排名靠前的几个alignment,
无法确
: 认具体是genome里哪个repeat
: 2)其中一个read能map到repeat边缘的unique区域,那么这个read能输出unique
: alignment。另外一个read输出排名靠前的几个alignment,这个可以通过自己写
的小脚
: 本只选择离unique mapped read最近的那个alignment。
: 3)两个read都是map到unique区域,这个就没有问题了。
: 根据上面的几种情况,虽然能得到一些uniquely mapped的read,但是也只是这个
: repeat附近ChIP的部分... 阅读全帖 |
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b*******s 发帖数: 954 | 36 第一道题,在elora 以及jbh2009的回答上,再补充一下
是Fragile X。
(1) X-link的疾病,现在的看法是x-dominant或者x-recessive的提法签妥当(请看
uptodate或者其他资源)
(2) 对Fragile X来说,5'-UTR的CGG有expansion.
Normal: CGG repeats < 45
Grey zone: 45 < CGG repeats < 55
Premutation: 55 < CGG repeats < 200
Premutation由于有较长的5'-UTR转录出的RNA, 这些RNA可能会特别稳定,作为sink,
和一些重要的蛋白作用,影响这些蛋白的功能。
Full mutation: 200 < CGG repeats
Full mutation的5'UTR被methylated, FXMR蛋白无法表达
Premutation和full mutation的重要差别是premutation仍然可以表达FXMR蛋白。所以
premutation和full mutation的症状非常不一样。premutation... 阅读全帖 |
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c*********d 发帖数: 9770 | 37 http://fashion.sina.com.cn/l/wa/co/2017-12-28/1020/doc-ifypwzxq6514858.shtml
2017年12月28日10:20新浪时尚
导语:三问报时腕表堪称精密机械工艺的稀世杰作,作为高级钟表界的无上天后,
深受收藏家和钟表爱好者的青睐。无论究其内部结构、材质和鸣响的音质,都是复杂功
能腕表里最为考究工艺与检验技术能力的,能够打造出一枚毫无技术瑕疵的三问表,更
是需要极高的制作门槛。在百达翡丽卓绝的高级制表工艺中,三问报时功能亦已成为品
牌的特色之一,并展现着品牌百年来传承的制表基因与核心价值。
三问报时装置
精密复杂的微机械装置邂逅美妙的报时鸣音
报时时计根据所搭载的报时机制、功能以及鸣响机制可分为刻钟报时、半刻钟报时
、五分钟报时、三问报时以及大、小自鸣。其中三问报时是最为常见且典型的报时功能
,也是众多报时时计种类中最具实用性的。
三问报时表,俗称“打簧表”。最早可追溯至17世纪末,当时欧洲的制表工匠在努
力研究如何制造一种装置,能在漆黑的环境下通过发出不同的声音进行报时。历史上第
一个报时装置的设计构思来自英国人... 阅读全帖 |
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c*********d 发帖数: 9770 | 38 http://fashion.sina.com.cn/l/wa/co/2017-12-28/1020/doc-ifypwzxq6514858.shtml
2017年12月28日10:20新浪时尚
导语:三问报时腕表堪称精密机械工艺的稀世杰作,作为高级钟表界的无上天后,
深受收藏家和钟表爱好者的青睐。无论究其内部结构、材质和鸣响的音质,都是复杂功
能腕表里最为考究工艺与检验技术能力的,能够打造出一枚毫无技术瑕疵的三问表,更
是需要极高的制作门槛。在百达翡丽卓绝的高级制表工艺中,三问报时功能亦已成为品
牌的特色之一,并展现着品牌百年来传承的制表基因与核心价值。
三问报时装置
精密复杂的微机械装置邂逅美妙的报时鸣音
报时时计根据所搭载的报时机制、功能以及鸣响机制可分为刻钟报时、半刻钟报时
、五分钟报时、三问报时以及大、小自鸣。其中三问报时是最为常见且典型的报时功能
,也是众多报时时计种类中最具实用性的。
三问报时表,俗称“打簧表”。最早可追溯至17世纪末,当时欧洲的制表工匠在努
力研究如何制造一种装置,能在漆黑的环境下通过发出不同的声音进行报时。历史上第
一个报时装置的设计构思来自英国人... 阅读全帖 |
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m**c 发帖数: 7349 | 39 Once we know about the effect we can guard against it. Part of this is
double-checking why we believe what we do – if something sounds plausible
is it because it really is true, or have we just been told that repeatedly?
This is why scholars are so mad about providing references - so we can track
the origin on any claim, rather than having to take it on faith.
But part of guarding against the illusion is the obligation it puts on us to
stop repeating falsehoods. We live in a world where the fact... 阅读全帖 |
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l*****r 发帖数: 687 | 40 跟你微信群玩了那么久,你连我是不是repeating还搞不清,给你我家地址,你不还是
傻傻的去找repeating?
万一我把repeating地址给你,你和星光不会把艾滋传染给repeating吧?
LOL |
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W*******n 发帖数: 4140 | 41 NYS Workers' Comp: How Alpha 3T MRI Fouls Even on The DVDs?
By Limin Wang
March 03, 2020
Introduction:
This realistic story mainly tells how a medical diagnostic imaging MRI
facility, Alpha 3T MRI (145 East 32 Street, Ground Floor, New York, NY 10016
. Phone: (212) 868-9210), gave me, an apparent workers’ compensation case (
NYS WCB# G2029240) patient but actually a victim of attempted murders, a DVD
completely blank in its content but with my information printed on the disk
skin, soon after the... 阅读全帖 |
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g********d 发帖数: 4174 | 42 Jump to…Top of pageAbstractIntroductionMaterials and
methodsResultsDiscussionConclusionAcknowledgementsReferences
Introduction
Top of page
Abstract
Introduction
Materials and methods
Results
Discussion
Conclusion
Acknowledgements
References
The National Blood Services of the UK have, since the early 1980s, asked men
who have ever had sex with men (MSM) to not donate blood. At first, this
action was motivated by the aim of preventing transmission by transfusion of
the infectious agent associated ... 阅读全帖 |
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l****z 发帖数: 29846 | 43 Obama’s Superbowl Sunday interview
Rarely has a lame duck emitted such a strange series of quacks, as President
Obama sat down for a pre-Super Bowl interview with Bill O’Reilly in which
the latter asked the kind of tough questions Obama’s adoring media never
asks… and Obama refused to answer any of them.
Remember how Obama said he was more angry and frustrated about the failure
of the ObamaCare launch than anyone? Forget all that. He’s not going to
hold anyone accountable – he thinks “accounta... 阅读全帖 |
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S*******h 发帖数: 7021 | 44 I think he will according to his response to CNN town hall last night.
http://www.cnn.com/2016/03/30/politics/republican-town-hall-tak
Trump, apologize?
It took Trump some time to answer when he was asked about the last time he
apologized for anything.
"Oh, wow," he said, as the audience laughed.
He finally came up with a response: "I apologized to my mother years ago for
using foul language. I apologize to my wife for not being presidential on
occasion. She's always saying, 'Darling, be more pr... 阅读全帖 |
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S******8 发帖数: 24594 | 45 Attorney General Loretta Lynch repeatedly dodged and deflected specific
questions Tuesday on the FBI’s probe of Hillary Clinton’s email use,
referring Republicans to the FBI director instead of answering them herself
– and leading to heated exchanges with top Republicans over the course of
several hours of testimony.
Rep. Trey Gowdy, R-S.C., said Lynch’s “lack of clarity is bad for the
republic.”
During questioning before the House Judiciary Committee, Rep. Jason Chaffetz
, R-Utah, also asked ab... 阅读全帖 |
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s*******f 发帖数: 1114 | 46 https://business.facebook.com/anticorruptusamedia
http://russp.us/racism.htm
A Short History of Democrats, Republicans, and Racism
The following are a few basic historical facts that every American should
know.
Fact: The Republican Party was founded primarily to oppose slavery, and
Republicans eventually abolished slavery. The Democratic Party fought them
and tried to maintain and expand slavery. The 13th Amendment, abolishing
slavery, passed in 1865 with 100% Republican support but only 23% Dem... 阅读全帖 |
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b*****d 发帖数: 61690 | 47 Bill Clinton says Trump's campaign slogan is racist
He used it repeatedly while running for president in 1991 and 1992,
declaring at one Little Rock, Ark., event, "Together, we can make America
great again."
Former President Bill Clinton might want to keep the racism accusations to
himself from now on -- after ripping Donald Trump for a slogan he's used
repeatedly since his 'Comeback Kid' days.
The 42nd president on Wednesday, while stumping in Orlando for Hillary
Clinton, suggested Trump’s camp... 阅读全帖 |
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b*****d 发帖数: 61690 | 48 One current and three former female lawmakers are the latest to say publicly
that they have experienced sexual harassment or inappropriate comments from
male colleagues on Capitol Hill.
Former Reps. Mary Bono (R-Calif.) and Hilda Solis (D-Calif.), former Sen.
Barbara Boxer (D-Calif.) and current Rep. Linda Sanchez (D-Calif.) told The
Associated Press that they experienced sexual harassment, including unwanted
sexual advances and demeaning comments, during their time at the Capitol.
While they di... 阅读全帖 |
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W***n 发帖数: 11530 | 49 Last updated: Aug. 30, 2017
Toyota Highlander Consumer Reviews and Complaints
Carmen of Lorain, Ohio Verified Reviewer
Original review: Aug. 30, 2017
It's great on gas, the body is strong and the engine is great. As for the
tranny, one can't feel it shift. Its air condition and heat is wonderful.
Overall, it's a great SUV.
HELPFUL Be the first one to find this review helpful
Cheryl of Bishop, CA
Original review: June 16, 2017
In 2015 I purchased a 2014 Highlander and began having electrical prob... 阅读全帖 |
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