d*******3 发帖数: 8598 | 1 虽然生物技术和制药产业的整体前景没有受到经济萧条的影响,但整个行业仍面临重大
的挑战。美国药物研发与制造商协会(PhRMA)指出,企业研发一种新药需要10??15年
的时间、超过12亿美元的投入。但一大批畅销药物的专利即将过期,制药业将面临数百
亿的损失。根据PhRMA的数据,2000年只有49%的处方使用非专利药,但这一比例现在已
达到84%。
最佳雇主如何克服这些重大挑战?首先,是将“科学”定位为组织机构的中心,并把科
学家放在最高领导层。在这些企业中,科学数据是决策和项目方向的驱动,从而将科学
家奉为“掌门人”。
“从整个创新的过程到从一个想法变成临床候选药物的速度,都让在这工作的人兴奋不
已。”位于纽约塔里敦Regeneron制药公司的研发科学高级副总裁Neil Stahl表示。该
生物技术公司已连续两年蝉联《科学》职业“最佳雇主调查”冠军。Stahl指出,公司
在研发用于降低胆固醇的单克隆抗体药物Alirocumab时,从一个想法到临床试验只用了
19个月。这个以创新闻名的公司依靠创新为源动力,打破了药物发现和开发的瓶颈。
“迄今我最喜欢这个公司的是,你进房间时可能只有一丝想... 阅读全帖 |
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t*******r 发帖数: 364 | 2 大家怎么看这个问题
http://top-stories1.blogspot.com/2013/05/titanic-mysteries-reve
Titanic Mysteries Revealed
Titanic Mysteries Revealed. Mystery of incident that happened a few years
ago, and that caused a stir was the reemergence of luck Ships Titanic
victims are still alive. Two victims of the Titanic disaster in 1912,
suddenly appeared in the state are still alive. Physically they do not
change exactly as before. Theory of the passage of time has been answered.
Among the victims were lucky, that one ... 阅读全帖 |
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a*******a 发帖数: 451 | 3 Summary:
- He grew up in a poor messed up family.
- Wanted to get filthy rich because he thought money would bring him all he
needs in life.
- Was able to compartmentalize his conscience because of his poor view of
humanity, due to shitty upbringing.
- Was introduced to someone that told him he could make as much as he wanted
if he gave them a cut.
- Got involved in high level money manipulation, laundering to govts, secret
agencies, and terrorists.
- Was eventually invited to church of satan wh... 阅读全帖 |
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b*w 发帖数: 277 | 4 Sarah McLachlan
×××
Spend all your time waiting for that second chance
For the break that will make it ok
There's always some reason to feel not good enough
And it's hard at the end of the day
I need some distraction oh beautiful release
Memories seep from my veins
They may be empty and weightless and maybe
I'll find some peace tonight
In the arms of an Angel fly away from here
From this dark, cold hotel room, and the endlessness that you fear
You are pulled from the wreckage of your silent reve |
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q**i 发帖数: 174 | 6 the gt-s is basically a mr2 in reverse: a front-engined mr2.
it is much bigger and more practical than the mr2 (but
also smaller). It also has a firmer suspension to go
with it. Very nice looking IMHO.
the SR5 is a 5-spd corrola with cosmetic upgrade. I
don't remember it being that different from a
normal corrola.
the 4age engine is a high reve engine used in corolla,
mr2 and celica of that era. With a tvis (toyota variable
intake system), it is quite good a screamer for a small
car.
very rarely |
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h*******o 发帖数: 778 | 7 一个2008 mercury sable premier, 配置moon roof, leather, bluetooth sync, reve
rse sense radar, 14500 miles. One owner.
私人卖车,需要$15k cash + tax. 这个车性价比如何? Emunds trade-in clean 价格
:$14,737. |
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f****o 发帖数: 4067 | 8 when engine's not reving, there's no torque. When you rev it, mounts should
hold engine still. Assuming mounts failed, that's why you should test them.
this is what i'm talking about. https://www.youtube.com/watch?v=hoDfmowLnes |
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k*****n 发帖数: 9823 | 9 ☆─────────────────────────────────────☆
ibd (这是一种病) 于 (Tue May 31 16:11:57 2005) 提到:
稍微忙一点,就觉得花两个小时看个片子可能,安安静静听两个小时音乐就有点坐不住。
☆─────────────────────────────────────☆
fotoid (oneshot) 于 (Tue May 31 21:18:48 2005) 提到:
seems you didn't really enjoy the music.
☆─────────────────────────────────────☆
lechery (GIS) 于 (Wed Jun 1 00:45:02 2005) 提到:
我对视频感兴趣,这个也是家庭影院最主要的部分
☆─────────────────────────────────────☆
yfei (one flew over...) 于 (Wed Jun 1 01:46:12 2005) 提到:
for me, the reve |
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w****n 发帖数: 1737 | 10 from wsj,
"First, the good news, in the words of analyst Rick Summer:
The industry is young, but we are very positive on the prospects for the
company.
Awesome. Now, the bad news:
Still, even good companies should be bought for less than they are worth
.
Our fair value estimate of $27 assumes LinkedIn extends its dominance as
the preferred social-networking site for professionals. We are forecasting
annual revenues to increase 43% during the next five years, as combined reve
nues fro... 阅读全帖 |
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d**********0 发帖数: 13081 | 11 包括两张 Le Reve -- The Dream.... |
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m****u 发帖数: 718 | 15 O show必看,我们当时跟朋友排队的买的退票,选了差不多最好的座位,就是价钱不便
宜,不过真的很值得。还有blue man,Le Reve Show 也超级精彩 |
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M*****8 发帖数: 17722 | 16 SPY, DIA and QQQQ are all very close in terms of readings.
Bear in mind that this is a pre-election, political rally, with significant
artificial price-lift.
The market appears very much over-bought, however, so it may not look good (
for the bulls) right after the election, as price-lift is no longer useful.
Always scale in and scale out, whether bearish or bullish, that way you don'
t miss the ride and can also average down your cost if prices get even more
extreme (i.e. favorable) before reve |
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w********1 发帖数: 3492 | 17 best gain is AKAM 35 put 4times
best stock gain is ggg up 10%
most unlucky one is idcc, beat on both reve and earning but drop 5% more.
uncertain one but probably wise bidu put spread 150/145 and 150/140
worst option bet is LZ, bid/ask is like 0.20 : 0.95. can't exit anything
nomatter right or wrong
other bet yesterday include xlnx ebay fisv eqix re wll srcl sbux.... |
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v****e 发帖数: 19471 | 18 this guy's got some good points:
"What is a TV but a 60" computer screen? Ours has 3 or 4 input devices (Wii,
DVD, HD cable box, Roku, etc) that are essentially no different than the ha
rd drive or DVD drive on my laptop. The TV is hard-wired to "cable" as oppos
ed to wireless to the router, but that difference is irrelevant -- we get Ne
tflix via the Wii from the wireless router link. The hard-wired cable connec
tion is essentially just our 200 "favorite sites to link to"... or they shou
ld be.... 阅读全帖 |
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s***m 发帖数: 6197 | 20 agree!
The S&P 500 Effect: Not Such Good News in the Long Run
Daniel Cooper
Board of Governors of the Federal Reserve System
Geoffrey Woglom
Amherst College*
Abstract
This paper analyzes the effect on a company's stock price when it is added t
o the S&P 500 Index. A simple theoretical model is developed to show how tr
ading effects and changes to fundamentals should affect the price of S&P 500
additions upon announcement and in the long run. This model predicts that
a company added to the S&P ... 阅读全帖 |
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x*********n 发帖数: 28013 | 22 每天有一万个讨论。
一万个说它好,一万个说它不好。
里面有无数专业人士机构来说他。
so, you dont know。
短期看,负面新闻很多,随时也可能会爆发。
长期看,国米都在,最怕出一个jobs在谷歌,那果果就彻底完了,不然我觉得长期没风
险。
果果的成功就是因为出了一个jobs,改变了世界,打败了所有的手机平台,2/3的reve
来自手机,产品risk太高。
如果真有爆炸recall,真的会暴跌了。 |
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l*****u 发帖数: 1788 | 23 我08年10月1日OPT-H1,老婆一直F1,两个人都不够5年,两个人在一个州但不是一个城
市。两个人入境签证都是F1。
现在可以选择都报NR,或者extenstion报joint
而且我想把08年1月到10月交的ssn,med退回来
现在的问题:
1.extension的话,我没弄明白是h1 status in 2009 183days 还是 h1 in 2009 in U.
S. 183 days... 因为3月份要出差回上海,现在的签证,最差的可能弄不好5,6月份
才回来。
我是不是要考虑extension到10月啊?
如果只是H1身份够天数就简单多了。
2.如果考虑退ssn和medi的话,还能不能joint as RA呢
查到的资料,
a nonresident alien who makes an election to file a joint
return under IRC 6013(g) is treated as a resident alien only for the
purposes of:
1. Chapter 1 of the Internal Reve |
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b****a 发帖数: 8 | 24 不管你有没有到过拉斯维加斯,都应该知道“秀”,每个赴拉斯维加斯的游客,包括明
星在内都会特地去看“秀”。拉斯维加斯“秀”,是其他地方难得一见的视觉盛宴。
拉斯维加斯有多少场秀呢?说法是:一年365天,即使你每晚看一场,恐怕也看不完。
对于前往拉斯维加斯的游人说,住上一年,可不太现实,每天都看,恐怕也太奢侈。他
们必须要有所选择——至少有8场你秀是你必看的。
1.拉斯维加斯之 O Show/水秀(小编强烈推荐,虽然票价小贵,但是非常值得)
在拉斯维加斯最著名的百乐宫Bellagio Hotel欣赏拉斯韦加斯最著名的秀,是加拿大马
戏团Cirque du Soleil的最新巨作,率先尝试水上剧场。拥有 81 位跨国艺人的强大阵
容,在 150 万加仑 (568 万公升) 的池水中以及池水表面和上方演出。场面壮观,非
常令人震惊且富有创意。
2.拉斯维加斯之 Zarkana
太阳剧团制作的Zarkana,在壮观场景中呈现充满视觉盛宴和震撼的现代特技表演,超
乎常人所及的身体能力于此一一具现。跟着魔术师Zark一同踏上重拾魔力与生命热情的
旅程,走入住着各式疯狂角色和高超特技演员的荒废剧院。引... 阅读全帖 |
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B*****s 发帖数: 3463 | 25 抓紧送医学院... 厉害
不是啊,我们住在Reve山脚的地方,Revere不是好区,可是学校里有尖子班,我的孩子
一直都在尖子班,交的朋友也是尖子班的同学,MCAST考试也都是在278,279, 2.....
... |
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L****e 发帖数: 858 | 27 去Vegas表忘了去Wynn看看,中国风,那的秀Le Reve(The dream)比Bellagio的O show还
好看,圣诞前去最好了,有圣诞树可以看,这个要数Bellagio最好了
Bay area往南去Monterey一定要去17mile阿,往北去Napa,市区看看斯坦福大学,De
Young Mesuem有时间看看。一周都能去Lake Tahoe了,这时候还能滑雪
码了这么多,能要包子么? |
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m**********8 发帖数: 584 | 28 travel 版上有人问关于vegas show的,我回了下面的, 抛个砖,大家给些补充。
下面的都是我看过觉得非常好的show.但是每个人喜好不同。Kerwin给mark一下,或者
放精华区把。哈哈
cirque de solei 的show
"O" at bellagio
"Ka" at MGM
"Le Reve" at Wynn
"Love" at Mirage ( if you are beetle's fan)
"Viva Elvis" at Aria ( if you are Elvis' fan)
"Zumanity" at New York New York ( 18+, sexiest show ever, i think)
other shows
"Blue man" at Venetian
"Frank Caliendo"at monte carlo ( impressionist, he has show on TBS as well,
if you have confidence in listening comprehension, it is good s |
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m*****y 发帖数: 438 | 29 Phantom of the opera现在在洛杉矶有的,我明天去看。
个人觉得la reve 比O好看。 |
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S******a 发帖数: 2369 | 31 Sounds ok. I got ones for Le Reve two month ago as 140+ per seat after
discount. The section was pretty much premier but at fifth row.
Opera |
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s*******g 发帖数: 1607 | 32 anyone has an opinion on which is better?
also does anybody know how to score cheap group tickets besides being a high
roller at the casino?
thanks |
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s*******g 发帖数: 1607 | 33 thanks man, long time no see |
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l*******h 发帖数: 156 | 34 Yes, long long time. We are at Irvine, and welcome to drive down here. |
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l*******h 发帖数: 156 | 37 Job/Life change. :-) Long time no see as well. |
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m*******e 发帖数: 1569 | 39 La Reve不错,strip太塞车,而且附近的道路似乎都年久失修,lz有空跟有关部门反映
反映,收了大家那么多的钱这市政工程搞的太差了也,:-) |
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G******l 发帖数: 2087 | 40 大道酒店都可以
高端:Wynn永利,bellagio,威尼斯,恺撒宫,城市中心包括:mandarin oriental,
the cosmopolitan,Aria,vdara.中端:巴黎,MGM,金银岛,等等,mriage,弗拉明戈。
低端:百利。
其他大道上的那几个不如不住。。还不如大道外火车头了。有的进去手机就一直处于无
信号状态下。。。
自助餐排名:第一:凯撒宫,第二:bellagio,第二:永利。
海鲜自助:RIO。
好看的show:O show,wynn的le reve,MGM的Ka等等等。
演出:凯撒的席琳迪翁,今年年底换成仙尼雅唐恩。 |
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G****a 发帖数: 10208 | 41 【 以下文字转载自 Travel 讨论区 】
发信人: z8 (z8), 信区: Travel
标 题: las vegas一些感受,小tip
发信站: BBS 未名空间站 (Wed Feb 1 16:53:29 2012, 美东)
版上关于lv的文章不是最多也是第二多了,不少游记和流水账之类的,我文笔一般,就
不凑热闹了,简单写一些自己的点滴感受,也算是回馈版面吧。
我和老婆12月22号-26号在lv待了4天,就在那条街上待了整4天,别的地方哪也没去,
临走时还是觉得意犹未尽,留点遗憾也好,下次才有动力再去。
1.衣
白天大概摄氏18-20度左右,在街上走,不需要穿外套,或者一件很薄的外套就足够了,但
是到了晚上还是有点冷,我们下飞机时晚上12点,我穿了件风衣都还觉得冷,所以如果
要在室外待到比较晚还是要备一件外套。
无论男的女的,我觉得最好还是带一套正装,平时生活中一般人穿正装的机会还是不多
,但是去了lv,机会还是不少的,餐馆啊,看show啊,而且,我觉得lv怎么穿都不算
over dress,女士们晚上穿件小礼服什么的在赌场里,商场里逛挺平常的。
2.食
buffet只吃了... 阅读全帖 |
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c******a 发帖数: 762 | 42 搞定回来了。。。加上share的油费,我跟一个朋友去了3晚4天,一共花了。。。。。
280多美金。。。呵呵
表演看了一场le reve的,酒店住一个3星酒店,和hilton酒店送6个自助餐,我们有2天
的午餐没有吃,然后赌钱输了60美金,反正一共加上就是那么多。。。所以去vegas也
不用那么多花费滴。。。
祝你们玩得开心 |
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L****n 发帖数: 3545 | 43 【 以下文字转载自 Travel 讨论区 】
发信人: desertfox (壹心悠), 信区: Travel
标 题: 又到岁末出行时,写点Vegas旅游简介 (转载)
发信站: BBS 未名空间站 (Mon Nov 14 10:32:41 2011, 美东)
发信人: desertfox (壹心悠), 信区: Texas
标 题: 又到岁末出行时,写点Vegas旅游简介
发信站: BBS 未名空间站 (Mon Nov 14 10:32:11 2011, 美东)
篇头提醒,长,慎入。。。如果入了就往下看吧。。。
此文看的时候需要自己做些功课,如果连几大旅馆位置都不懂的话,看完了也不知道我
说的景观在什么地方。我主要说些概述的东西,不是在写游记,没有兴趣列个什么时间
到什么地方的清单,既然出来玩了,就是要放松的,不用搞得跟赶场一样。另外每个
hotel有时候有package deal,找找看,应该还比较合算。如果自己出行的话,可以考虑
换一两个hotel,这样能把大部分景观看全。下面从住、行、食、玩等几方面大致提一下。
1.住,几大旅馆位置,及几个有特点的hotel
赌场大道上面有... 阅读全帖 |
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L****n 发帖数: 3545 | 44 【 以下文字转载自 Travel 讨论区 】
发信人: desertfox (壹心悠), 信区: Travel
标 题: 又到岁末出行时,写点Vegas旅游简介 (转载)
发信站: BBS 未名空间站 (Mon Nov 14 10:32:41 2011, 美东)
发信人: desertfox (壹心悠), 信区: Texas
标 题: 又到岁末出行时,写点Vegas旅游简介
发信站: BBS 未名空间站 (Mon Nov 14 10:32:11 2011, 美东)
篇头提醒,长,慎入。。。如果入了就往下看吧。。。
此文看的时候需要自己做些功课,如果连几大旅馆位置都不懂的话,看完了也不知道我
说的景观在什么地方。我主要说些概述的东西,不是在写游记,没有兴趣列个什么时间
到什么地方的清单,既然出来玩了,就是要放松的,不用搞得跟赶场一样。另外每个
hotel有时候有package deal,找找看,应该还比较合算。如果自己出行的话,可以考虑
换一两个hotel,这样能把大部分景观看全。下面从住、行、食、玩等几方面大致提一下。
1.住,几大旅馆位置,及几个有特点的hotel
赌场大道上面有... 阅读全帖 |
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L****n 发帖数: 3545 | 45 布拉吉奥的O SHOW和 WYNN的 LA REVE 都是场面很宏大的。挺好看的,就是比较贵。
如果想看稍“色”一点的, NYNY的 ZUMANITY 也不错。挺说CRAZY HORSE尺度更大,我
没看过。 LUXOR 的FANTASY 是泳装小姑娘们,估计你喜欢你LD不一定,哈哈。 MGM
有大卫科波菲尔魔术。凯撒宫定期有CELINE DION演唱会,具体时间你得查一查了。 |
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L****n 发帖数: 3545 | 46 布拉吉奥的O SHOW和 WYNN的 LA REVE 都是场面很宏大的。挺好看的,就是比较贵。
如果想看稍“色”一点的, NYNY的 ZUMANITY 也不错。挺说CRAZY HORSE尺度更大,我
没看过。 LUXOR 的FANTASY 是泳装小姑娘们,估计你喜欢你LD不一定,哈哈。 MGM
有大卫科波菲尔魔术。凯撒宫定期有CELINE DION演唱会,具体时间你得查一查了。 |
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L****n 发帖数: 3545 | 47 【 以下文字转载自 Travel 讨论区 】
发信人: yayajj (菜), 信区: Travel
标 题: las vegas, 吃喝娱乐休闲
发信站: BBS 未名空间站 (Sun Dec 11 22:51:10 2011, 美东)
Thanksgiving又 去了Las Vegas。最近几年,好像每年都会去Vegas,大多数时候是因
为去别的地方路过,稍作停留。因为不是赌徒,所以每次做的事都差不多,就是吃
BUFFET, 看SHOW。后来又发现了另一件消磨时间的事,那就是在HOTEL SPA买张DAY
PASS去泡澡。
在 VEGAS,几乎每个HOTEL都有它专门的SPA, 每家设施都有自己的特色。这次泡了两家
Sahra at Hotel Cosmopolitan ($28) 和Canyon Ranch at Hotel Venetian ($40,
will be $20 if you are guest in Venetian). Sahra有点失望,设施虽然新,但是并
没有什么特色,唯一的亮点是泡泡池里有一面是瀑布状水帘,异性休息室在二楼,除了
沙发茶水没什么特别可以... 阅读全帖 |
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L****n 发帖数: 3545 | 48 based on price and reputation:
1. O
2. La Reve
3. Blue Man Group
..
..
.. |
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