i*********5
发帖数: 19210 | 1 Power Meter Pricing Wars: Let The Games Begin
http://www.dcrainmaker.com/2015/04/power-meter-pricing-wars.htm
The Winds are a Shifting:
Over the past few weeks there have been a number of notable price drops by
power meter companies. While some of these price drops may seem reactionary
to news from PowerTap’s new products, or that 4iiii is now shipping
Precision units – the reality is that most of these were planned months ago
. Still, like when some gives you a candy bar – it’s best not to fo... 阅读全帖 |
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t********t
发帖数: 5415 | 2 看上去不错
公路踏板我是没见过平底鞋能踩舒服的...spindle在背面会鼓出来。个人觉得还不如踩
正面 |
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m****z
发帖数: 978 | 3 不用说，大家也能知道不是俺写的。。
Has swimming got you over a barrel?
One of the most misunderstood elements in swimming is the "high elbow." For
most of my life that phrase has been spoken with the intent of the elbow
remaining high during the swimmer's recovery, that is, when the swimmer's
arm is out of the water. The listener also, more often than not, thinks of
recovery when he hears "high elbow."
In fact, most really good swimmers I know don't give much of a hoot what you
do with your arm when it's not in ... 阅读全帖 |
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l******i
发帖数: 171 | 5 前来学习。我喜欢看跟儿童读物有联系的书or电影。最近看的不多，能想起来的是neil
gaiman 短篇小说集里为数不多的可以给小孩子读的几个：the sleeper and the
spindle,chu's day.有一些fairy tale retelling类别的可以给孩子看看。不过他的书
总体来讲比较暗黑。。。。有很多空间和时间上的twist，幻象和现实交织，大部分更
适合大人or至少是teen吧。给teen的话，the thing about cassandra，the case of
death and honey之类的也有意思。
不知道如何附图片。。。。 |
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g****d
发帖数: 3461 | 6
"In the original sleeping beauty, the lovely princess is put to sleep when
she pricks her finger on a spindle. She sleeps for one hundred years when a
prince finally arrives, kisses her, and awakens her. They fall in love,
marry, and (surprise surprise) live happily ever after. But alas, the
original tale is not so sweet (in fact, you have to read this to believe it.
) In the original, the young woman is put to sleep because of a prophesy,
rather than a curse. And it isn’t the kiss of a prince ... 阅读全帖 |
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f****g
发帖数: 379 | 7 body是这样做的。大致把形状锯出来。然后在上面贴一块MDF的模板。用router就可以
把边缘整齐的车下来。
右边那个机器就是router。你可以看见黄色的router bit。那是一个带着轴承的刀片。
左边是一个spindle sander，可以用来做模板。
下面是些模板
others
five |
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T******e
发帖数: 18290 | 10 我估计在美国肯定难通过。
★★★★ ★★★★ ★★★★
“一爸两妈”宝宝有望降生英国
Paradoxian 发表于 2014-07-31 18:18
更新：2015年2月4日，英国下议院以382票对128票的大比分优势，通过了相关修正案。
程序上讲法案还需经上议院批准，但否决可能性极小。由此，英国基本确定成为第一个
允许体外人工受精中使用线粒体捐献的国家。
在英国，大约每6500个新生儿中就有一个患有严重的线粒体病，包括一些类型的肌营养
不良（muscular dystrophy）、莱伯遗传性视神经病变（Leber hereditary optic
neuropathy）和莱氏综合征（Leigh syndrome）等。在咨询了公众意见和进行安全性及
有效性评估后，政府做出决定：英国政府将出台方案，允许在体外人工授精（in vitro
fertilization, IVF）过程中进行线粒体捐献，用来自健康女性的线粒体置换掉有缺
陷的线粒体，使这些孩子能够避免患上线粒体疾病。
线粒体DNA是完全通过母系家族遗传的，只能从妈妈遗传给孩子，患有线粒体病的女性
会将有缺陷的线粒体遗传给宝宝。要... 阅读全帖 |
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i******e
发帖数: 171 | 11 in Homo sapiens
Nitzan Mekel-Bobrov,1,2 Sandra L. Gilbert,1 Patrick D. Evans,1,2 Eric J.
Vallender,1,2 Jeffrey R. Anderson,1 Richard R. Hudson,3 Sarah A. Tishko
ff,4 Bruce T. Lahn1*
The gene ASPM (abnormal spindle-like microcephaly associated) is a speci
fic regulator of brain size, and its evolution in the lineage leading to
Homo sapiens was driven by strong positive selection. Here, we show tha
t one genetic variant of ASPM in humans arose merely about 5800 years ag
o and has since swept to hi |
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T*******y
发帖数: 6523 | 12 I want to start a new post on this question, also as a response to Yisu's
post earlier.
I also feel that the will to understand the Truth is very important, and it
is closely related to the faith.
Well, what is the will to find the Truth? What is it exactly? Is it the
belief that there must be a reason, aka, karma? Is it the faith that there
must be a way out, aka, nirvana? Or is it the intuition (built-in essence of
a soul, or collective unconscious, or whatever it's called) that keeps
calling ... 阅读全帖 |
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K*****k
发帖数: 1611 | 13 呵呵，你好像问不只一个问题
will, belief, intuition,
GOD(s), truth, faith, time...
估计没有一个是有标准答案的
就个人感觉友情灌点水。
“Well, what is the will to find the Truth? What is it exactly? Is it the
belief that there must be a reason, aka, karma? Is it the faith that there
must be a way out, aka, nirvana? Or is it the intuition (built-in essence of
a soul, or collective unconscious, or whatever it's called) that keeps
calling on us to pursue it?”
不太清楚，但是圣经里的一句话，
比较符合我的感觉
...and the truth will set you free." (John 8:32)
“Do yo... 阅读全帖 |
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T*******y
发帖数: 6523 | 14 This is very refreshing for me to hear.
In the book "The Conversations with God", the "God" explained the time
concept using the analogy of a spindle of pages, where each time instance is
a page, so there is some vertical relation as "past", "now" and "future",
and people can peek through them, such as remembering past lives, predicting
futures, the psychic ability to sense others' lives, etc; however, all is
already there, all is already present.
It's like if one has the awareness to see one pa... 阅读全帖 |
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Y**u
发帖数: 5466 | 15 ☆─────────────────────────────────────☆
dukkha (沉浮颠倒之心) 于 (Wed Dec 7 20:12:47 2011, 美东) 提到:
无论别人怎样议论大乘，都应作为修忍辱波罗蜜。尽量不加入争讼。实在不行，回一声
佛号，南无本师释迦摩尼佛，也是功德无量。
何况大乘小乘虽然对于阿罗汉等的地位有所争议，但是都同尊三宝，都承认三法印，都
愿意以释迦摩尼本尊为师。
而对待小乘，应当恭敬。华严经善财童子五十三参，对对方都恭恭敬敬对待。这是大乘
弟子应当效仿学习的。
☆─────────────────────────────────────☆
freeman08 (平常心) 于 (Wed Dec 7 21:09:38 2011, 美东) 提到:
我觉得，本来没有什么大乘弟子、小乘弟子，只有学佛法的，和不学的。
学的时候，你的程度和当下心机兴趣在某个点上，这个程度可高可低，但都可能
是在那条路上。
就好象科学，本来只有一个科学，没有初中科学，高中科学，大学科学，
所以也没有什么你信仰初中科学，他信仰高中科学，再一个信仰大学科学... 阅读全帖 |
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w**u
发帖数: 311 | 16 sekon 兄，你的一些问题, 已超出我的能力.如有不当，请包含。
关于色法里的四大，我一直对禅修高人能看到物质色聚中的四大存疑。对我来说，用
仪器观察道亚原子的基本粒子更可信，甚至超弦的假设也比他们的理论也更有意义。
实践上，我只听说柏奥体系对观色法色聚四大有要求。
相反，名法中的四大，我觉得非常可信。
因为我认为原始佛教中的”名法”是基于高度训练过的许多牛人对自身感官体验的重复性
的理性总结.每个禅修牛人就好像一个高分辨，超高帧，大容量的超级显微镜。只不过，
对象是自己量子意识的变化。
基于此,我更倾向不把里边的名法当作形而上的哲学. 而他讲的许多体验,应该可以得到
现代生物的佐证. 反过来，现代神经生物学也能帮助我们禅修实践。
比如这里这个身念住里的观四大, 其分类跟神经生理许多地方不谋而合：
体位觉,或者叫本体感 (proprioception),它的感受器主要是肌梭(Muscle
spindle),高尔基体（Golgi organ，golgi tendon organ) 等.所以我把它归为风大。
温热觉(thermoreception), 它的感受器是游离神经末稍, 主要的离... 阅读全帖 |
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S***n
发帖数: 1281 | 17 谢谢师兄！不管是跟我相同或者跟我相左，总是在inspire我。
有关神经的那段，你是说神经体系正好分为四大类，所以应该正好是分管四大的？
你说到名法与色法的差别，你是说，感受到的，因为没有显现，所以属于名法，不属色
法吗？
跟你讲一下我看到的经历，你看是不是不光是名法了。我的眼睛，真的成显微镜了，比
显微镜还牛。当然，还没有达到你说的那个量化的微细尺度。
我的眼睛，可能因为里面有飞蚊的原因，有的时候会莫名地聚焦到很近的位置，显著的
例子，就说我躺在沙滩上睡觉，醒来的时候不睁眼，眼前看到的是一片通红，那是被太
阳照到的结果。但是很多次就能看到眼皮里放大了的毛细血管，红细胞在视野中穿过，
一顿一顿地在走的，与脉搏对应。
后来有几次在闭关室，感觉黑屋子里眼前有微暗的条状物，并且还分区呈方块状整齐排
列，每个方块中有七八条不规则排列的条条。开始以为是幻觉看到什么甲骨文了，闭关
心里淡然不在意，慢慢也就看不到了。
后来跟同修交流，也有说看到的，并且强调是进门的时候。这下引起我钻研的劲头了，
我进闭关室一看，果不其然，就是刚开始的时候有，慢慢就没有了。
这让我想起萤光物质。所以我就快速开关一下闭关... 阅读全帖 |
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L**1
发帖数: 12 | 18 This position will extensively conduct and participate modeling, analysis,
problem solving and innovations for HDD actuator and spindle motor using
ANSYS, Analysis Work Bench, MATLAB, etc.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
• Perform extensive FE modeling and analyses using ANSYS and ANSYS
Workbench
• Conduct the root cause diagnosis on dynamics and solid mechanics
related issues
• Interpret the FEA results and provide the physics of root causes
and solutions
• Active |
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m**x
发帖数: 8454 | 19 【 以下文字转载自 Military 讨论区 】
发信人: ibmgoog (mitotic spindle), 信区: Military
标 题: 看见一个搞笑的。
发信站: BBS 未名空间站 (Tue Jun 4 11:29:28 2013, 美东)
rt |
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s*******y
发帖数: 46535 | 20 【 以下文字转载自 Shanghai 讨论区 】
发信人: mdmx (没大没小), 信区: Shanghai
标 题: 看见一个搞笑的。 (转载)
发信站: BBS 未名空间站 (Tue Jun 4 13:26:04 2013, 美东)
发信人: ibmgoog (mitotic spindle), 信区: Military
标 题: 看见一个搞笑的。
发信站: BBS 未名空间站 (Tue Jun 4 11:29:28 2013, 美东)
rt |
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i****a
发帖数: 36252 | 21 is your tempdb on the same spindle as data and log files? see if you can
separate them. I know with SAN it's hard to tell/manage but that's one
thing to look at.
another thing to try is multiple tempdb files. |
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w****b
发帖数: 118 | 22 1.Check if your tempdb lun is srdf. If yes, You do not need srdf for tempdb
lun.
if this is not cluster server, You might consider put tempdb in local.
2.Check the raid type, raid10 is better. Storage guy will argue raid 50 and
raid 10 are the same.
3.You might want to enable T1118 flag if you see a lot of waitresource on
PFS or sgam page.
4.Add more spindles to the tempdb lun to improve the i/o performance. |
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g***l
发帖数: 18555 | 23 *是OLTP的SERVER，不过网站用很多的STORED PROCEDURE PULL DATA，因为每一CLICK都
要RUN SP，BUSINESS SERVER CACHE好多,每隔一个小时REFRESH一次
*2 nodes cluster
*去看了一下，没有什么设置可以调，用的是DELL MODULAR DISCK STORAGE MANAGER
显示ARRAY IS OPTIAML
你说的这些都不知道哪里去改，T1118 flag force to use uniformed extent,我觉得
帮助不大，Add more spindles to the tempdb 还是多弄几个FILE吧，我已经有16个
FILE了，MS有的说一定要1 CPU-1TEMP FILE,还有说最多8个的。
tempdb
and |
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w*r
发帖数: 2421 | 24 Depends on the hardware model.
Appliances 26xx/27xx are less expensive. EDW 6xxx is much more expensive.
The difference is primarily number of disk spindles per CPU which yields to
drastically IO characteristic.
Teradata is in Data warehouse and BI arena. OLAP is the major strength. Not
suitable for low latency high OLTP application.
upfront cost depends on the number of nodes and configuration.
Teradata does not sell software, it sells solution, which includes hardware
and software. Annual cost... 阅读全帖 |
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b********7
发帖数: 12906 | 25 > 500GB means multiple spindles. |
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a*o
发帖数: 19981 | 26 Seagate is wrong, silicon is the future. Sooner or later NAND will be
cheaper than spindle on $/GB base.
When China is able to produce NAND chips like plastic toys ...
It wont take long, 5-10 years more than enough. |
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r*a
发帖数: 1503 | 27 非常感谢！ 电源，显卡有什么可以推荐和它搭配的嘛？
这里就是400块的那个组合。
MSI P67A-C43 B3 Intel P67 Motherboard
Processor Socket: Intel
Processor Interface: LGA1155
Form Factor: ATX
Processors Supported: 2nd generation Intel® Core™ i3
2nd generation Intel® Core™ i5
2nd generation Intel® Core™ i7
Additional Technologies: THX TruStudio PRO
MSI ClickBIOS
Military Class II
OC Genie II
Northbridge: Intel® P67 Express
Memory Supported: DDR3 1333MHz
DDR3 1066MHz
DDR3 1600MHz (... 阅读全帖 |
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a*o
发帖数: 19981 | 28 只用来装系统，哥64GB用了几年了也没啥不够，什么还有20GB的VM。
哥不装大游戏，但是大软件也是装了不少的。data都流放到spindle上。 |
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C*******t
发帖数: 169 | 29 最近硬盘出现了寿终正寝的迹象。Dell 的小二推荐了他家的硬盘，
1 TB 7200 RPM Serial ATA Hard Drive for Dell Inspiron $148.99
Tech Specs
General
Device Type
Hard drive - internal
Capacity
1 TB
Interface
Serial ATA-300
Performance
Spindle Speed
7200 rpm
Expansion & Connectivity
Interfaces
1 x Serial ATA-300
Compatible Bays
1 x internal
我在STAPLES家看到一样规格的硬盘， 但是SEAGATE 牌子的， 只有$95.
请问SEAGATE的能和DELL的OEM 阮件兼容吗？能卖SEAGATE 的吗？
在此提前感谢您的建议。 |
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g*****9
发帖数: 349 | 30 请问西数的高端产品比如Black和RE系列是不是好很多。感觉价格贵了几乎一倍。。。
spindle count 只有一半。 |
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a*o
发帖数: 19981 | 31 百分百是硬盘的问题，320G的spindle硬盘? 你也好意思装到这么一台机器上。。。 |
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n***w
发帖数: 2405 | 33 我原来读过04年neuron上一篇文章：Mitotic spindle regulation by Nde1 controls
cerebral cortical size. |
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m****n
发帖数: 75 | 34 I have a postdoctoral position open and was wondering who would be
interested in joining my laboratory to work on the kinesin motors and their
mechanism of function in vitro and in the spindle. I am especially
interested in applicants who have a strong background in biophysics and also
have experience in structural biology and biochemistry.
该教授主页
http://www.cellbio.duke.edu/faculty/research/Endow.html |
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m***f
发帖数: 1622 | 35
扯淡呢，看看高最近两年发表的文章吧
CELL STEM CELL, JBC, STEM CELL, PNAS，都是很不错的
就这样还不能PROMOTION? 在美国都可以tennure了
1. Wu T., Wang H., He J., Kang L., Jiang Y., Liu J., Zhang Y., Kou
Z., Liu L., Zhang X., Gao S. (2011) Reprogramming of trophoblast stem
cells into pluripotent stem cells by Oct4. Stem Cells 2011 Feb 8.
[Epub ahead of print].
2. Kang L., Wu T., Tao Y., Yuan Y., He J., Zhang Y., Luo T., Kou Z.,
Gao S. (2010) Viable mice produced from 3-factor induced pluripotent
stem (iPS) cells through tetrapl... 阅读全帖 |
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a********k
发帖数: 2273 | 36 花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
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n***g
发帖数: 5027 | 37 人的卵跟小鼠的差别特别大，
小鼠的卵肉眼能看见spindle，人的根本看不见，
所以去小鼠卵的染色体基因组相对容易点，人的就太难了，而且人卵不好搞啊 |
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u**********d
发帖数: 573 | 38 据我所知有如下的方法：
离心把核甩掉——有点粗暴，细胞器都跑到一边去了，还漏不少出去，不过确实方便；
用空针吸——这是最常见的不多说；
化学诱导——用etoposide，etoposide，cycloheximide 处理，可以让整个spindle加
上所以染色体都跑到polar body里去；
仿佛记得有个紫外烧的方法，找不到了。
还有其它方法吗？请补充，谢谢。 |
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h******y
发帖数: 351 | 39 你说的比较温和是指什么？
来源于很多组织的人的fibroblast可以通过overexpress hTERT得到immortalization，
这是由于人的fibroblast在体外培养条件下的senescence多是由于端粒渐行缩短而导致
的（telomere-dependent replicative senescence）。与人的fibroblast不同，体外
培养中MEF的senescence并不是由于端粒缩短引起的,而是由于如前所述的过氧基团累积
oxidative stress induced DNA damage。研究表明senescence的MEF的端粒还很长，而
且MEF中有较高的mTERT表达，所以过表达mTERT并不能有效immortalize MEF。因为要抑
制p53和Rb通路，所以表达异源的SV40 T和HPV16 E6/E7都可以immortalize MEF。当然
这样得到的细胞株，由于这些病毒蛋白的过量表达，基因组并不稳定，长久培养会出现
嬗变。
3T3办法引起的自发immortalization实际上主要是由于自发的p53通路抑制（p53 loss... 阅读全帖 |
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l********n
发帖数: 260 | 40 Science. 2011 Jul 15;333(6040):342-5.
Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway
determines lung tube shape.
Tang N, Marshall WF, McMahon M, Metzger RJ, Martin GR.
please send to a*************[email protected]
Thanks a lot!! |
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l**********1
发帖数: 5204 | 42 Omg! FAQ her/is credit might be stolen !
if below Science paper last corres author Dawson DS read FAQ her/is
manuscript before Lol
pls refer Sci magazine advanced online release,
'Mps1 and Ipl1/Aurora B Act Sequentially to Correctly Orient Chromosomes on
the Meiotic Spindle of Budding Yeast.'
by
Meyer RE et al. and Dean S. Dawson
HTTP: //www.sciencemag.org/content/early/recent bla bla bla
31 January 2013 Science.1232518 |
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f*****f
发帖数: 195 | 43 不过前几年一般每年都是几个million，据说是非常非常nice的人，手下出来的PI都有
几十人了，现在做spindle assembly的很多PI或多或少都跟他实验室有关系。 |
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a*******a
发帖数: 4233 | 44 一般dna dsb以后被nhej修复时容易出现。njej非特异性连接末端后有的染色体有两个
centromere,有的染色体一个
都没有。一个都没有的染色体在细胞分解时没东西拉着就会掉出来形成micronulei,，
有两个centromere的会被拉向相反的方向最后拉断，(breakage-fusion-bridge)并且减
慢分解速度甚至干脆
spindle无法分离最后形成一个两个核的细胞。
当hr通路失活时这种现象比较多。 |
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w*********1
发帖数: 27 | 45 请问您可以看到在interphase的filament以及在mitosis的spindle么？我构建的GFP-
Tubulin绿色荧光超强，可就是看不到丝状结构。看上去也不是GFP，因为在间期里细胞
核没有绿色，绿色都在细胞质里面，但是就是diffuse在细胞质里，不形成微管结构，
这个让我很惆怅。 |
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L**1
发帖数: 12 | 46 Our group is actively looking for the candidate, pls see the following:
The engineer in this position will extensively conduct and participate
modeling, analysis, problem solving and innovations for HDD actuator and
spindle motor using ANSYS, Analysis Work Bench, MATLAB, etc.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
• Perform extensive FE modeling and analyses using ANSYS and ANSYS
Workbench
• Conduct the root cause diagnosis on dynamics and solid mechanics
related issues
• Inter |
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L**1
发帖数: 12 | 47 The engineer in this position will extensively conduct and participate
modeling, analysis, problem solving and innovations for HDD actuator and
spindle motor using ANSYS, Analysis Work Bench, MATLAB, etc.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
• Perform extensive FE modeling and analyses using ANSYS and ANSYS
Workbench
• Conduct the root cause diagnosis on dynamics and solid mechanics
related issues
• Interpret the FEA results and provide the physics of root causes
and |
|
y*h
发帖数: 2121 | 48 简易的装置有那种viscometer吧，用个合适的Spindle应该就能测的。
我们用的是Brookfield Viscometer。 |
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h***a
发帖数: 312 | 49 1. During an experiment, the following data are obtained from an
anesthetized dog:
Mean glomerular capillary hydrostatic pressure (HPGC) 45 mmHg
Mean Bowman space hydrostatic pressure (HPBS) 12 mmHg
Mean glomerular capillary oncotic pressure (piGC) 23 mmHg
Mean Bowman space oncotic pressure (piBS) 0 mmHg
Coefficient of filtration (Kf) 3.0 (mL/min)/mmHg
Renal Blood Flow 200 mL/min
Hematocrit 40%
Filtration Fraction 25%
An IV infusion of AngII is administered for 60 minutes. Which of the
fol... 阅读全帖 |
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s*******d
发帖数: 1079 | 50 学友MILK找到的这个FA ２０１１版 vs ２０１０版的详细对照，我觉得很有帮助，放
在这儿给大家做参考吧。
原文见 http://forums.studentdoctor.net/showthread.php?t=785943
Overall:
- FA 2011 corrects some of the 2010 errata
- FA 2011 has darker print and thicker pages
- FA 2011 increases the size of most figures/images (although only slightly)
- FA 2011 removes several images that are difficult to see/interpret
Behavioral Science:
p. 59-60 2010 (57-58 2011) -2011 reorganized a couple items into "Advance
directives" and got rid of "Good Samaritan Law.... 阅读全帖 |
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