c***l
发帖数: 238 | 1 还有一个复旦转学到美国的。
Majored in Biochem, 1980-83, Fudan University, Shanghai
B.A. in Biochem, 1985, SUNY at Stony Brook
发信人: ipdang (iphone5), 信区: Biology
标 题: New elected NAS members
发信站: BBS 未名空间站 (Tue Apr 30 11:05:44 2013, 美东)
http://www.nasonline.org/news-and-multimedia/news/2013_04_30_NA
The National Academy of Sciences announced today the election of 84 new
members and 21 foreign associates from 14 countries in recognition of their
distinguished and continuing achievements in original research.
... 阅读全帖 |
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a******s
发帖数: 267 | 2 又想了一下，对照组太小还是一个问题。Tom Sanders的comment认为应该考虑玉米储藏
不当引起的mycotoxins，这通常是强致癌物质，玉米中常见的是Zearalanone，而且
Sprague-Dawley rats又容易生癌。如果对照组又太小，对他们的数据还是有一些打击
的。 |
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C********4
发帖数: 308 | 3 据说这个品系的大鼠很容易就长肿瘤。
http://songshuhui.net/archives/72927
－－－－－－－－－－－
引言
2012年9月19日的Food and Chemical Toxicology（食品与化学毒理学）期刊上，刊登
了一篇名为“农达除草剂与抗农达基因修饰玉米的长期毒性”的论文。这项研究使用
200只大鼠进行了为期两年的研究，得出的结论是：极低浓度的农达除草剂（比现有安
全剂量还低）和NK603抗农达转基因玉米（占被试小鼠食物的11%-33%）都有明显的致癌
效果。
这个结论会引起轩然大波，因为……“农达”作为一种农药都已经使用40余年，连专利
都过期了，美国环保署（EPA）将它的毒性归为3级，在农药中几乎是最低毒的了；而抗
农达玉米也早已在美国、加拿大和南美洲多个国家广泛种植十多年了，其产品也喂养了
欧洲的大批牲畜。这项研究认为二者的健康风险都是极高的，但这却不符合之前的几乎
所有研究。
澳大利亚植物功能基因组学研究中心的Mark Tester教授这样评论：“跃入我脑海里的
第一件事是为什么在很早就有大量转基因食品进入食物链的国家中进行的流行病学研究... 阅读全帖 |
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i****g
发帖数: 3896 | 4 http://www.nasonline.org/news-and-multimedia/news/2013_04_30_NA
The National Academy of Sciences announced today the election of 84 new
members and 21 foreign associates from 14 countries in recognition of their
distinguished and continuing achievements in original research.
Those elected today bring the total number of active members to 2,179 and
the total number of foreign associates to 437. Foreign associates are
nonvoting members of the Academy, with citizenship outside the United States
.
N... 阅读全帖 |
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C*******e
发帖数: 4348 | 5 http://www.nature.com/nbt/journal/v31/n9/full/nbt.2700.html?WT.
真正想了解而不是想吵架的同学可以看看
还可以给身边对这个有疑问的朋友看看
也提到了去年法国的那个老鼠实验
还有黄金大米
Contrary to popular belief
Nature Biotechnology 31, 767 (2013) doi:10.1038/nbt.2700
Published online 10 September 2013
Three decades after transgenes were first introduced into plants, why do so
many consumers remain so negative about genetically modified (GM) food?
GM food has an uncanny ability to spook consumers. It does not matter that
many of us have been consuming GM ... 阅读全帖 |
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y***u
发帖数: 7039 | 6 看了两篇，第一片是个挑刺的老油条， 属于吹毛求疵，不值得一驳。
第二篇较为客观。
Most criticisms were of a general nature and without substance worthy of
entering the scientific debate. Some criticisms were specific, referring to
the type of rat used, the kind of statistical analysis, and the
interpretation of the response to increasing concentrations of the
agrichemicals, Roundup, or genetically modified plant ingredient.
I performed a quick review of papers on rat feeding studies using
genetically modified feed components also publi... 阅读全帖 |
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o********r
发帖数: 775 | 8 It has been shown that SD rats could develop spontaneous (fatal) tumors as
early as 11 weeks.
SON and GOPINATH (2004) Early Occurrence of Spontaneous Tumors in CD-1 Mice
and Sprague–Dawley Rats. Toxicol Pathol 32:371-374
http://tpx.sagepub.com/content/32/4/371.full.pdf
很低 |
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n********t
发帖数: 1079 | 9 40个老鼠在哪呢？另外您还得把这个SD母鼠自发肿瘤发生率就是80%甚至更高的地洗了
。。。
http://www.ncbi.nlm.nih.gov/pubmed/11381627
Neoplastic lesions were observed in untreated aged Sprague Dawley (SD) rats
throughout their lifespan starting at 5 weeks. Their mean survival times
were 89 to 105 weeks of age. The total tumor incidences were 70 to 76.7% and
87 to 95.8% in males and females, respectively. The common neoplasmas were
pituitary adenoma and adrenal pheochromocytoma in both sexes, testicular
Leydig cell tumor in males and mamma... 阅读全帖 |
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c***l
发帖数: 238 | 10 速度够快！
标 题: 北大生物系校友邓兴旺陈雪梅当选美国科学院院士！
发信站: BBS 未名空间站 (Tue Apr 30 11:56:12 2013, 美东)
还有一个复旦转学到美国的。
Majored in Biochem, 1980-83, Fudan University, Shanghai
B.A. in Biochem, 1985, SUNY at Stony Brook
发信人: ipdang (iphone5), 信区: Biology
标 题: New elected NAS members
发信站: BBS 未名空间站 (Tue Apr 30 11:05:44 2013, 美东)
http://www.nasonline.org/news-and-multimedia/news/2013_04_30_NA
The National Academy of Sciences announced today the election of 84 new
members and 21 foreign associates from 14 countries in rec... 阅读全帖 |
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d**********e
发帖数: 72 | 12 SDN网上有主治医生撰长文说过：tunable diaphragm科技实际上会正确使用的医生不多
，并不很好。Welch-Allyn Harvey Elite受到高度评价
The tunable diaphragm will miss sounds at the extremes of the frequency, ie.
very low, and very high, and will not filter out unwanted frequencies.
Based on the research by Rappaport and Sprague in the '50s A tight diaphragm
is needed to detect high frequencies, and a deep bell with a sharp edge is
needed to detect low ones.
Other findings included dual lumen tubing at specific lengths of 14", 18",
or 25" (if m |
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S*****4
发帖数: 153 | 14 http://www.amazon.com/Omron-Sprague-Rappaport-Stethoscope-Black
I bought this one, cheap and reasonable! I borrowed a short white coat. It
doesn't matter, it is short or long like regular lab coat. All AMG are in
short one, IMGs are in long one. They will provide you a sticker to cover
any label on your coat. |
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s**********8
发帖数: 25265 | 15 Good Laboratory Practice
In the experimental (non-clinical) research arena, the phrase good
laboratory practice or GLP specifically refers to a quality system of
management controls for research laboratories and organizations to try to
ensure the uniformity, consistency, reliability, reproducibility, quality,
and integrity of chemical (including pharmaceuticals) safety and efficacy
tests.
GLP was instituted following cases of animal test fraud by pharmaceutical
and industrial chemical (mainl... 阅读全帖 |
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b******k
发帖数: 1136 | 21 赞珍贵屁屁鸟!
俺也想看啊...
★ 发自iPhone App: ChineseWeb 7.8 |
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v**********m
发帖数: 5516 | 23 楼上文章的comments
Not yet but stay tuned. But a definite fact and you can review it in the FDA
's analysis in the briefing document is that there was no SS of astrocytomas
in male rats or female rats.
Dr. Alavi had concerns about how Arena calculated the exposure margin for
Lorcaserin, that is why it appeared in the CRL. When Arena met directly with
the FDA on December 15th and 16th at the FDA, both Arena and the FDA agreed
on the CSF methodology and the number of participants that would be
acceptab... 阅读全帖 |
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