e*****n
发帖数: 3129 | 1 谁敢说这兔子不反刍
http://news.nationalgeographic.com/news/2011/03/110323-giant-ra
Christine Dell'Amore
National Geographic News
Published March 22, 2011
The Easter bunny came early this year for a few scientists working on the
Spanish island of Minorca (see map).
The team has just announced the discovery of Earth's biggest known rabbit
species, an oddly unbunny-like giant dubbed Nuralagus rexquot;the Minorcan king
of the hares."
The 26-pound (12-kilogram) prehistoric species was about six times bigger
t... 阅读全帖 |
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N****f
发帖数: 25759 | 2 *Bow* The greatest accomplishment I have ever managed to
achieve in the field of vertebrate biology... |
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J*****3
发帖数: 4298 | 5 http://dsc.discovery.com/dinosaurs/
Dinosaurs are a diverse group of animals of the clade Dinosauria. They first
appeared during the Triassic period, approximately 230 million years ago,
and became the dominant terrestrial vertebrates for 135 million years, from
the beginning of the Jurassic (about 200 million years ago) until the end of
the Cretaceous (65.5 million years ago), when the Cretaceous–Paleogene
extinction event led to the extinction of most dinosaur groups at the close
of the Mesozo... 阅读全帖 |
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j*******7
发帖数: 6300 | 6 【 以下文字转载自 BibleStudy 俱乐部 】
发信人: jmsma2007 (James), 信区: BibleStudy
标 题: [ZT] 生物学历史上的一个骗局
发信站: BBS 未名空间站 (Fri Nov 9 18:47:08 2012, 美东)
http://cclw.net/gospel/explore/mdjhl/htm/03.htm
每一个人的胚胎在发育过程中都有一个鱼的时期，外形跟鱼的胚胎相似到离奇的程
度呢？
生物学在自然科学中，是最复杂又是最年轻的一门学科。百多年来不断地成长，到
如今可以说达到突飞猛进的地步。每天在新闻报导中都可以听到有新的生物学发现。不
少人都认为廿一世纪肯定是生物学的世纪。在这成长的过程中，随著观察和实验的增加
，当然会修正过去的一些错误。
但是在1997年，生物学上有一个重大的发现，这个发现不是“修正”过往的错误，
而是揭开了生物学历史上最大的丑闻（注１），也可以说是最大的骗局－－科学家兼名
教授海克尔伪造图片、蓄意欺骗。
但是据我所知，在美国除了两家科普性的杂志（注2）（注3）对此做了简单报导之
外，各大城市的报章杂志都丝毫... 阅读全帖 |
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d**********u
发帖数: 4124 | 8 ☆─────────────────────────────────────☆
Brandon (大奔◎仰望蓝天) 于 (Sat Apr 18 16:58:23 2009) 提到:
欢迎兄弟院校来稿。
发信人: Brandon (大奔◎仰望蓝天), 信区: THU
标 题: 清华大学九十八周年校庆征文活动隆重开幕
发信站: BBS 未名空间站 (Sat Apr 18 15:40:41 2009), 转信
亲爱的各位校友，THU版的各位网友：
大家好！
西山苍苍，东海茫茫，转瞬间，母校即将迎来九十八岁华诞！九十余载岁月悠悠而过
，母校留给每一个学子的，都是难以忘怀的记忆！两年前，本版曾成功主办“九十六周
年校庆征文活动”，获得网友的热烈响应和积极参与，并涌现了一批精彩好文，其中一
些已经被清华招生网转载。两年后，同样在这个季节，同样在这个舞台，让我们用更加
精彩的表演为母校献上最诚挚的生日祝福！
本版特隆重推出九十八周年校庆征文活动，现将有关事项说明如下：
1、征文时间：即日起至2009年5月10日止。
2、征文内容：与清华有关的重要人物、重大事件的追忆，或者是亲历者、见证者... 阅读全帖 |
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B*****n
发帖数: 498 | 9 大家有什么建议？
至于奖金，希望众位小盆友捐赠伪币，本铺将铭刻捐赠榜，永久mark，以示后人。
We proudly recognize individuals below for their generous contributions.
(sum = 6330.34)
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***** Bronze Spon |
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m********o
发帖数: 1539 | 10 ☆─────────────────────────────────────☆
vertebrate (我乃脑残体开山祖师) 于 (Tue Dec 9 18:58:26 2008) 提到:
The more breakups one has, the more ______________. |
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k****i
发帖数: 3282 | 11 你有vertebrate那样的贤侄你怎么可能烂。
我知道这句没逻辑，请领会精神。 |
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p******h
发帖数: 577 | 13 发信人: vertebrate (The Man In A Case), 信区: THU
标 题: Re: 不知道将来怎么办?
发信站: BBS 未名空间站 (Sat Jul 19 18:21:53 2008), 转信
这些坑都不好看，水木下面这个十大才有观赏性，真tm jp：
发信人: CCTV9 (努力做厚道人,嘿嘿), 信区: FamilyLife
标 题: 我给了婆婆一巴掌zz....
发信站: 水木社区 (Sun Jul 20 00:02:12 2008), 站内
转载.......
发信人: hawkingsjuju (吆五喝六的), 信区: love
标 题: 我给了婆婆一巴掌zz....
发信站: 两全其美网 (Sat Jul 19 00:29:34 2008), 本站(lqqm.net)
刚才，三分钟之前，我抽了我婆婆一个大耳光，现在手还生疼，不过，爽的很...
是不是会有人骂我以下犯上，咳，先听我说说理由再骂...
我老公家里是陕西汉中的，虽说也算个城市，但是经济落后，穷啊，我老公家呢，更穷
，我
公公是个木匠，我婆婆是个生产塑料桶的什么厂里的流水线上的工人，工资很 |
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c******a
发帖数: 267 | 14 Nature Genetics Vol32, Oct,2002 p306P311
Human securin interacts with p53 and modulates p53-mediated transcriptional
activity and apoptosis.
The first report show the relevance between human securin and p53.
The gene PTTG1 is considered human securin gene which can inhibit
sister-chromatid separation in vertebrates, thus may contribute to cell-cycle
and tumorigenesis. The authors used phage display to identify the interaction
between hPTTG1 and p53, and they carried out a series of functional a |
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x***m
发帖数: 184 | 15 最近也对zebrafish感兴趣，可惜周围都没有实验室可以交流。
请问现在大家用zebrafish做模式生物的研究热点有那些? 较之于其它vertebrate模式
生物如frog, chicken和mice有那些特别的优势呢, 除了比较透明?
美国有哪些做zebrafish的好实验室？ |
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S*********e
发帖数: 127 | 16 High-throughput in vivo vertebrate screening.
Pardo-Martin C, Chang TY, Koo BK, Gilleland CL, Wasserman SC, Yanik MF.
Nat Methods. 2010 Aug;7(8):634-6. Epub 2010 Jul 18.
a*****[email protected]
thanks a lot. |
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b*****e
发帖数: 288 | 17 各位思考这个问题之前，先看看人类的一些特有特征：
1. 人类脚部有其他灵长类动物没有的跟腱。
2. 人类有其他灵长类动物没有的小汗腺，密度高达80～600个/cm2。
3. 一般动物脑中的血液只能通过Meningeal Vein和Diploic Vein循环到肺。而人类头盖骨上有密集和粗壮的Emissary Foramina。大脑中的静脉血由此透过头盖骨流到头皮中散热，之后进入Vertebral Venous Plexus到肺。这样可以使脑部迅速散热。
4. 人类有长并且不断生长的头发。一方面可以遮阳，另一方面增加汗液蒸发的表面积，配合Emissary Foramina为头部降温。另外人类其他大量排汗的部位也有毛。
5. 化石和分子进化证据表明人类祖先曾经在非洲长期生活。
6. 人类皮肤的排汗效率是马的十倍以上。
7. 人类有黑色皮肤抵挡紫外线。
8. 非洲土著San族人，可以在炎热的中午以每小时20公里的速度连续奔跑4个小时以上。
为什么人类没有厚重的体毛？
答： 因为人类祖先需要在白天极其炎热条件下长途奔跑追逐猎物，脱毛是为了散热。
本人自己总结的，如果觉得答案有道理就给包子。 |
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s**a
发帖数: 1906 | 18 我觉得你说的有一定的道理
毛发的脱落确实可能和散热有关
不少动物换毛就是冬天毛厚点，夏天毛少点
而寒带的动物明显毛发会多
看过说黑人头发卷曲也是为了散热
但是原理忘记了。
不过头发本身肯定不是为了散热吧
夏天热了很多人都知道去剪个短头发。。。
另外很多动物发育的时候，
尤其是雄性毛发都会产生很大改变的
而且这些毛发在吸引异性的时候还是很重要的。
毛多大概表示雄性激素分泌的多点？
是不是人类在某些地方留点毛发也和这个有关系？
头盖骨上有密集和粗壮的Emissary Foramina。大脑中的静脉血由此透过头盖骨流到头
皮中散热，之后进入Vertebral Venous Plexus到肺。这样可以使脑部迅速散热。
积，配合Emissary Foramina为头部降温。另外人类其他大量排汗的部位也有毛。
上。 |
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S***6
发帖数: 431 | 19 一方面我觉得你说的很有道理呢！赞一个！
另一方面，还有些疑问：
1：狮子老虎豹子也需要捕猎，也是经常奔跑啊？为什么没有脱毛呢？
2：人类的毛其实是很细的软毛，和动物身上的粗硬的毛根本就不是一类这个怎么解释？
3：另外，人类身上还有三处地方毛并没有退去，根据你的理论，能否解释为什么是这
三个地方呢？你只解释了一个，但是好像很勉强。
头盖骨上有密集和粗壮的Emissary Foramina。大脑中的静脉血由此透过头盖骨流到头
皮中散热，之后进入Vertebral Venous Plexus到肺。这样可以使脑部迅速散热。
积，配合Emissary Foramina为头部降温。另外人类其他大量排汗的部位也有毛。
上。 |
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y***i
发帖数: 11639 | 20 this looks professional.
头盖骨上有密集和粗壮的Emissary Foramina。大脑中的静脉血由此透过头盖骨流到头
皮中散热，之后进入Vertebral Venous Plexus到肺。这样可以使脑部迅速散热。
积，配合Emissary Foramina为头部降温。另外人类其他大量排汗的部位也有毛。
上。 |
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b****r
发帖数: 17995 | 21 其他基本同意，有毛增加汗液挥发表面积，这个比较扯。那穿了衣服表面积还更大呢，
那么多纤维
头盖骨上有密集和粗壮的Emissary Foramina。大脑中的静脉血由此透过头盖骨流到头
皮中散热，之后进入Vertebral Venous Plexus到肺。这样可以使脑部迅速散热。
积，配合Emissary Foramina为头部降温。另外人类其他大量排汗的部位也有毛。
上。 |
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h********4
发帖数: 1 | 22 Faculty Positions
The Institute of Genetics and Developmental Biology (IGDB), Chinese Academy
of Sciences (CAS), the neighborhood of Beijing Olympic Village, has several
openings for group leaders to join the Key Laboratory of Molecular &
Developmental Biology of CAS.
IGDB is a leading institution of life sciences in China. IGDB currently
hosts 63 research groups, of which 18 groups are actively involved in
addressing fundamental questions in animal development using model organisms
such as C. e... 阅读全帖 |
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M*****n
发帖数: 16729 | 23 this is better studied in Drosophila, but a fly is a fly.
don't know how much we can apply this to vertebrates. |
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p*****m
发帖数: 7030 | 24 这是个问题 说大点就是fish有点不尴不尬的，如果说做保守的东西还不如fly/worm又快
又便宜 reagent也发达；如果说一定要接近人，那fish和mammal还是差的挺多的，就连
frog都不如。说了20多年还是坐定一个所谓的研究vertebrate发育的model来用，我一个
门外汉的感觉就是有点为了搞个model system而model system的意思。
我感觉现在可以慢慢的用fish做一点本来设计之外的东东了 说不定可以更好地利用fis
h的优点。比如说，体外受精这个好处是不是可以用来系统的做epigenetic control,甚
至做reprograming的东西（如果frog不方便的话）？还有，larvae早期脑袋还是透明的
，用来搞很fancy的neural circuitry study会不会很爽？用来做neurodegeneration/r
egeneration会不会很方便？更不要说drug screen了，如果能想出好的assay来潜力非常
大啊，最近几个用fish做的发育之外的screen都很有意思，一个sleep的，一个optomot
or re... 阅读全帖 |
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f**u
发帖数: 346 | 25 来得有点晚了，好像错过了不少讨论。
我觉得fish有一个优点是作为vertebrate，还是可以做genetic screen的。
这个又接到之前的另一个话题了，我记得看到过用鱼来做forward screen筛隐性突变体
的。
不过这个还是局限在发育的范畴，不过如果能用鱼把脊椎动物的发育搞清楚也很好。 |
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c******m
发帖数: 884 | 26 好歹zebrafish算是vertebrate, 还是要比fly/worm进化了的。 |
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s********r
发帖数: 312 | 27 The standard neutral model and a selective sweep:
higher vertebrates do not have a high enough reproductive rate to support
rapid rates of beneficial evolution. It takes too many deaths to select for
new mutations.Kimura reasoned the majority of new mutations must be ‘
neutral’ The rate of neutral evolution could be much faster than positive
evolution, and would be limited only by the rate of DNA copying errors.
Since natural selection will not act on neutral traits, which do not affect
survival... 阅读全帖 |
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j******i
发帖数: 939 | 28 -6, -3 plus +4 are most important positions. In your case(+4 is not G ), so
put GCCACC(which is consensus sequence among vertebrates) before the start
codon theoretically should be more optimal than just CACC. |
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g**********t
发帖数: 475 | 29 teleost fish里有一次，early vertebrate里有两次（2R hypothesis）。budding
yeast里面有一次（约100 million years以前）。植物历史上还有多次。综述一搜能搜
到一大堆。 |
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n******7
发帖数: 12463 | 30 也许可以用UCSC genome browser
用Multiz Alignments of 46 Vertebrates， 把你的exon序列BLAT到MM9，然后看看其
他物种alignment的情况 |
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i****g
发帖数: 3896 | 31 引用200次以上的4篇：
Title: Directional guidance of neuronal migration in the olfactory system by
the protein Slit
Author(s): Wu W; Wong K; Chen JH; et al.
Source: NATURE Volume: 400 Issue: 6742 Pages: 331-336 Published: JUL
22 1999
Times Cited: 319 (from Web of Science)
Title: Vertebrate slit, a secreted ligand for the transmembrane protein
roundabout, is a repellent for olfactory bulb axons
Author(s): Li HS; Chen JH; Wu W; et al.
Source: CELL Volume: 96 Issue: 6 Pages: 807-818 DOI: 10.10... 阅读全帖 |
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B*****e
发帖数: 1005 | 32 140后的几个也不是美国AP啊，文章比跟前几个有距离
140 黄亿华 男 1971年10月 中国科学院生物物理研究所 生命
科学 2004年02月毕业于[美国]康奈尔大学 [美国]休斯医学研究所/西南医学中
心 讲师
1: Huang Y, Smith BS, Chen LX, Baxter RH, Deisenhofer J. Insights into pilus
assembly and secretion from the structure and functional characterization of
usher PapC. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7403-7. Epub 2009
Apr
20. PubMed PMID: 19380723; PubMed Central PMCID: PMC2670885.
2: Lin SC, Huang Y, Lo YC, Lu M, Wu H. Crystal structure of the BIR1 doma... 阅读全帖 |
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h*******o
发帖数: 4884 | 33 "most animals at wild die long before they reach the beginning of their
reproductive senescence"
That is not true at least for mammals.
Is there any evidence to support IGF1's impacts on the length of reproductive competent period in vertebrates or mammals?
From I know, it is quite the opposite. IGF1 knockdown impairs animal fertility in both sexes although it is known to increase lifespan.
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y******8
发帖数: 1764 | 34 I think it also true for most mammals, including small, middle and even some
big-sized ones.
IGF-1 knockdown surely impairs fertility. In theory, if the animal gets
endocrine regulation on IGF-1 production in response to harsh environment,
the animal would halt the reproductive activity. When condition improved,
the IGF-1 level would go back and the reproduction can be continued. Thus,
the energy and effort would not be wasted because raising infants would be
much more difficult than maintaining... 阅读全帖 |
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D*a
发帖数: 6830 | 35 : "most animals at wild die long before they reach the beginning of their
＝＝＝＝
This is true
小鼠在自然界中平均寿命也就六个来月，不可能活到两年多。中国古代女子15岁及笄（
可以嫁人），加上解放前平均寿命30岁的数据，所以能作用于reproduction的基因肯定
是跟寿命有这样那样的联系的。
现在说得通的寿命理论（evolutionary theory of aging），我觉得并不是突变积累和
抗氧化，而是kirwood的disposal soma，由willarms的antagonistic pleiotropy发展
而来，中心思想是能量的分配，这个理论认为，机体soma是用来支持生育的，现在的长
寿实际上是要求用更多的能量来维持机体的功能，所以不可避免要从其他地方（例如生
育能力）调出能量，从这个角度可以理解抑制growth hormone/IGF-1通路，或者
caloric restrition，可以影响机体的能量分配方式。
突变积累和抗氧化，我认为只是作用方式
reproduct... 阅读全帖 |
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H****N
发帖数: 997 | 36 Your statement about Pax6 in octopus is misleading. The following is direct
quote from the paper you provided:
"This view has been changed, however, by Gehring and Ikeo
(1999), who maintain that the expression of the common master
regulator Pax6 in both types of eyes indicates the divergence of
these two types of eyes from a single prototype eye present in the
common ancestor of cephalopods and vertebrates. It has previously
been reported that Pax6, a “master control” gene for the
development of... 阅读全帖 |
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D*a
发帖数: 6830 | 37 我喜欢这句话！
Moreover, Jules was very far from the actual‘bench work’. I think it fair
to say that he has always felt better among vertebrate immunologists than
Drosophila geneticists. |
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h****i
发帖数: 204 | 38 申请了K99，回答了review的问题后，Advisory Council和Council Meeting推荐给。去年PO在电话里口头说如果没有国会不cut NIH的funding太厉害就给钱（但他们没有留下任何字面证据，要写也是regarding the POSSIBLE funding ）。可是Project Period Begin Date已经过去了两个月还没有消息，email给PO泥沉大海。问另外一个Grants Management Specialist，告知Vertebrate Animal还没review好。唉，真难搞啊！看来还是那些回国找千青的好啊。然后想改budget，皮球踢来踢去的看了是没戏啦。
哪里都是politics，中国的那套好歹还能稍微看懂一点，这里可是一团雾水。各位大侠有grant拖几个月的吗？ |
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y*****0
发帖数: 15 | 39 不用担心，肯定有的。
去年PO在电话里口头说如果没有国会不cut NIH的funding太厉害就给钱（但他们没有留
下任何字面证据，要写也是regarding the POSSIBLE funding ）。可是Project
Period Begin Date已经过去了两个月还没有消息，email给PO泥沉大海。问另外一个
Grants Management Specialist，告知Vertebrate Animal还没review好。唉，真难搞
啊！看来还是那些回国找千青的好啊。然后想改budget，皮球踢来踢去的看了是没戏啦。
侠有grant拖几个月的吗？ |
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L*******e
发帖数: 2153 | 40 最近都怕被cut 掉，不仅是k99，我老板的r01，top 10% 都怕cut。今天问了问， 还算
fine。希望赶紧得到！可以买更多的antibodies! lol
去年PO在电话里口头说如果没有国会不cut NIH的funding太厉害就给钱（但他们没有留
下任何字面证据，要写也是regarding the POSSIBLE funding ）。可是Project
Period Begin Date已经过去了两个月还没有消息，email给PO泥沉大海。问另外一个
Grants Management Specialist，告知Vertebrate Animal还没review好。唉，真难搞
啊！看来还是那些回国找千青的好啊。然后想改budget，皮球踢来踢去的看了是没戏啦。
侠有grant拖几个月的吗？ |
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l**********1
发帖数: 5204 | 41 only for paralogous
please go to
//www.ncbi.nlm.nih.gov/pubmed/15865991
its page one:
What is paralogy?
Since Darwin, for most biologists (or at least, for evolutionary biologists) homology has
come to mean something like ‘similarity due to common descent’, to distinguish it from
similarity due to convergent evolution. An accurate understanding of the relationships
between living things depends upon correctly identifying homologous characteristics of
an organism from other similarity. A classic ... 阅读全帖 |
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b****n
发帖数: 110 | 42 Marie Curie POST-DOC fellowship application
University of Barcelona, Department of Genetics
Our new group on the field of Functional Evo-Devo and Genomics on Chordates
is looking for candidates to apply for the forthcoming FP7 POST-DOC
FELLOWSHIP from the Marie Curie program (Opening call March 13)
Candidates have to be enthusiastic, and need to have a competitive CV to
successfully apply for the fellowship. Experience in Molecular Genetics,
Transgenesis and Developmental Biology, and (or) Backg... 阅读全帖 |
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l**********1
发帖数: 5204 | 43 linker-based PCR
plus
iMapper soft:
//www.ncbi.nlm.nih.gov/pubmed/18974167
//geocachingsoftware.com/imapper.html
more details
please to to E-Book
Chapter 2:
its link:
FTP://ftp.sanger.ac.uk/pub4/theses/kong/chapter2.pdf
citation:
>Based on these expectations, a web-based server called iMapper (Insertional
Mutagenesis Mapping and Analysis Tool) was developed for the efficient
analysis of insertion site sequence reads against vertebrate and
invertebrate Ensembl genomes. Taking linker-based PCR se... 阅读全帖 |
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l**********1
发帖数: 5204 | 44 please try direct micro injection donor mtDNA to your target organism.
please refer
Takeda K et al
Influence of Intergeneric/interspecies Mitochondrial Injection; Parthenogenetic Development of Bovine
Oocytes after Injection of Mitochondria Derived from Somatic Cells. (2012)
J Reprod Dev. 2012 Mar 9. [Epub ahead of print]
PubMed link:
//www.ncbi.nlm.nih.gov/pubmed/22447326
Ps:
two us mentors of this aspect in Auburn University
College of Veterinary Medicine
Auburn, Alabama
a) MICHAEL H. IRWIN... 阅读全帖 |
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d*e
发帖数: 843 | 45 One of the leading biological physicists of his generation has died.
Tom Duke was born in Claygate, Surrey, on 14 March 1964 and received a
scholarship to study at King's College School, Wimbledon. A degree in
natural sciences at Emmanuel College, Cambridge (1982-85), was followed by a
PhD in polymer physics at the Cavendish Laboratory (1985-88).
After a short period as a postdoctoral research assistant at the Cavendish,
Professor Duke left the UK to take up a position as a Marie Curie Research
... 阅读全帖 |
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S*********s
发帖数: 304 | 46 生物谷小编的数据你都敢信？
里面只要是有一个China的都被他们算成大陆的文章
试举一例如下：
A High-Coverage Genome Sequence from an Archaic Denisovan Individual
Matthias Meyer1,*,‡,
Martin Kircher1,*,†,
Marie-Theres Gansauge1,
Heng Li2,
Fernando Racimo1,
Swapan Mallick2,3,
Joshua G. Schraiber4,
Flora Jay4,
Kay Prüfer1,
Cesare de Filippo1,
Peter H. Sudmant6,
Can Alkan5,6,
Qiaomei Fu1,7,
Ron Do2,
Nadin Rohland2,3,
Arti Tandon2,3,
Michael Siebauer1,
Richard E... 阅读全帖 |
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s******9
发帖数: 283 | 47 http://www.sciencemag.org/content/early/2013/03/06/science.1236
The Brain Activity Map
A. Paul Alivisatos1,*,
Miyoung Chun2,
George M. Church3,
Karl Deisseroth4,
John P. Donoghue5,
Ralph J. Greenspan6,
Paul L. McEuen7,
Michael L. Roukes8,
Terrence J. Sejnowski9,*,
Paul S. Weiss10,
Rafael Yuste11,*
Abstract
Researchers propose building technologies to enable comprehensive mapping
and control of neural circuit activity.
Neuroscientists have made impressive advances in understanding the
microscale ... 阅读全帖 |
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p*****c
发帖数: 20445 | 48 A-D E-K L-P R-Z
Peter Baumann, Ph.D.
HHMI Early Career Scientist
Stowers Institute for Medical Research
Peter Baumann’s research focuses on beginnings and endings: beginnings in
the form of reproduction in unisexual lizards and endings in the form of the
telomeres that protect chromosome tips.
Each time chromosomes are copied, telomeres—specialized stretches of DNA
that extend from the ends of each chromosome—become progressively shorter.
With each cell division, they ero... 阅读全帖 |
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p*****c
发帖数: 20445 | 49 Christopher D. Lima, Ph.D.
Memorial Sloan-Kettering Cancer Center
Christopher Lima doesn’t pick easy problems. A structural biologist, he is
investigating how cells attach small proteins—like ubiquitin and the
related molecule SUMO—to other proteins to modify their function or fate.
Alongside those studies, he is exploring the molecular mechanisms that
underlie RNA processing and degradation—modifications to an RNA copy of a
gene that influence its stability and ability to be used as a template ... 阅读全帖 |
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w***a
发帖数: 432 | 50 这片文章里有讲过一点。和shRNA一样表达。
@Article{Chen2004,
Title = {MicroRNAs modulate hematopoietic lineage
differentiation.},
Author = {Chang-Zheng Chen and Ling Li and Harvey F
Lodish and David P Bartel},
Journal = {Science},
Year = {2004},
Month = {Jan},
Note = {mark},
Number = {5654},
Pages = {83--86},
Volume = {303},
Abst... 阅读全帖 |
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