最近对这个histone acetylation and deacetylation 调控基因表达挺有兴趣,就这个
HDAC好像很多文章的结论 contradictive . 不知道该怎么follow 了,是不是这方面很
难研究啊,还请有做这方面的牛兄弟给点意见。
刚发现澳大利亚一个组的一篇JBC文章,看摘要觉得挺有趣的,可是看全文发现被撤销了
VOLUME 284 (2009) PAGES 35101–35112
DOI 10.1074/jbc.A209.061903
Histone deacetylase-1 is enriched at the platelet-derived
growth factor-D promoter in response to interleukin-1
and forms a cytokine-inducible gene-silencing complex
with NF-B p65 and interferon regulatory factor-1.
Mary Y. Liu and Levon M. Khachigian
This art