if yes, how to map the pore region for this channel? is there any
program/software can be used provided the sequence of the transmembrane
protein is known?
Thanks so much!
i***R 发帖数: 663
2
通道至少2次跨膜。pore region 位于两个transmembrane domain 之间,距离不长。通
道pore region 往往是最为conserved 的区域。
可以把这一区域试试跟已知ion channel 序列进行比对。有可能发现相似性。