a**p
发帖数: 49 | 1 我来起个头
手段上
多种体液的使用
和非纯化直接检测
效果上
灵敏度和特异性
还有什么癌症难检测的么 |
a**p
发帖数: 49 | |
a**p
发帖数: 49 | 3 no one say sth?
dont discuss rao yi la |
w*****y
发帖数: 35 | 4 你的题目太大了，癌症有很多种啊
【在 a**p 的大作中提到】
: 我来起个头
: 手段上
: 多种体液的使用
: 和非纯化直接检测
: 效果上
: 灵敏度和特异性
: 还有什么癌症难检测的么
|
K******S
发帖数: 10109 | 5 your ID keeps everyone away.
【在 a**p 的大作中提到】
: no one say sth?
: dont discuss rao yi la
|
a**p
发帖数: 49 | 6 为什么
我是新进的PI
现在在思考一些什么样的问题能做研究啊
大家帮忙建议 |
a**p
发帖数: 49 | 7 肝癌
乳腺癌
大肠癌
前列腺癌
卵巢癌
都可以啊
【在 w*****y 的大作中提到】
: 你的题目太大了，癌症有很多种啊
|
K******S
发帖数: 10109 | 8 pubmed search "proteomics, cancer biomarker", 10s of thousands of them per
year. FDA approves less than 1 per year. go figure.
hehe
【在 a**p 的大作中提到】
: 肝癌
: 乳腺癌
: 大肠癌
: 前列腺癌
: 卵巢癌
: 都可以啊
|
w***e
发帖数: 269 | 9 I agree. Don't do cancer. Do something else. I was thinking maybe some rare
genetic diseases are worth trying. I can't provide an example, but I am
thinking something nobody has done will give you the freedom to explore
without intense pressure of competetion and you can build your career on it.
【在 K******S 的大作中提到】
: pubmed search "proteomics, cancer biomarker", 10s of thousands of them per
: year. FDA approves less than 1 per year. go figure.
: hehe
|
K******S
发帖数: 10109 | 10 Actually, that's not my original intention.
NCI still pours tons of money into the field.
The problem is nobody can get fund for validation projects and the bar set
for "biomarker" is way too low.
rare
it.
【在 w***e 的大作中提到】
: I agree. Don't do cancer. Do something else. I was thinking maybe some rare
: genetic diseases are worth trying. I can't provide an example, but I am
: thinking something nobody has done will give you the freedom to explore
: without intense pressure of competetion and you can build your career on it.
|
|
|
l*h
发帖数: 4124 | 11 瑞士的PI就这点儿夸夸其谈的本事？这也太次了。
【在 a**p 的大作中提到】
: 为什么
: 我是新进的PI
: 现在在思考一些什么样的问题能做研究啊
: 大家帮忙建议
|
a**p
发帖数: 49 | 12 我在国内医院的
来这边访问交流
你好像很瞧不起人 |
l*h
发帖数: 4124 | 13 是啊，你们的基本训练也太差了。咱也没听说过assitant professor的头衔。
【在 a**p 的大作中提到】
: 我在国内医院的
: 来这边访问交流
: 你好像很瞧不起人
|
l*h
发帖数: 4124 | 14 你至少得知道点肿瘤研究的现状吧，一点儿都看不出来诶。
【在 a**p 的大作中提到】
: 我在国内医院的
: 来这边访问交流
: 你好像很瞧不起人
|
l****y
发帖数: 398 | 15 I have this silly question in my mind: can they reliably tell if the sample
is from a male or female by using any
proteomic "biomarker" from 体液?
【在 a**p 的大作中提到】
: 我来起个头
: 手段上
: 多种体液的使用
: 和非纯化直接检测
: 效果上
: 灵敏度和特异性
: 还有什么癌症难检测的么
|
K******S
发帖数: 10109 | 16 It's certainly possible but no one will do it because no agency will fund it
.
sample
【在 l****y 的大作中提到】
: I have this silly question in my mind: can they reliably tell if the sample
: is from a male or female by using any
: proteomic "biomarker" from 体液?
|
l****y
发帖数: 398 | 17 of course.
I just think it is an interesting test to evaluate the technology.
I hope they can get >50% correct in the end.
it
【在 K******S 的大作中提到】
: It's certainly possible but no one will do it because no agency will fund it
: .
:
: sample
|
K******S
发帖数: 10109 | 18 when I was in graduate school, one PI run tons of LC-MS/MS on his project.
The result can easily group pregnant women vs. non-pregnant women. LOL, even
himself was joking that he invented the most expensive pregnancy test in
the world.
The Y chromosome is gotta be generating some unique proteins. hehe
【在 l****y 的大作中提到】
: of course.
: I just think it is an interesting test to evaluate the technology.
: I hope they can get >50% correct in the end.
:
: it
|
l****y
发帖数: 398 | 19 he must be looking at some steroid compounds. That's pretty established just
like these tests in olympics.
is there any proteinic sexual maker in the body fluid especially plasma? if
so, how reliable can they detect it?
I have some doubts.
PS: I just got some information that pregnancy test is actually looking at a protein. sorry for my ignorance.
even
【在 K******S 的大作中提到】
: when I was in graduate school, one PI run tons of LC-MS/MS on his project.
: The result can easily group pregnant women vs. non-pregnant women. LOL, even
: himself was joking that he invented the most expensive pregnancy test in
: the world.
: The Y chromosome is gotta be generating some unique proteins. hehe
|
K******S
发帖数: 10109 | 20 I'm not in this particular field. But I guess anything related to prostate/
testicle should do it. Again, no one will spend time to test/develop such
thing anyway. hehe
just
if
a protein. sorry for my ignorance.
【在 l****y 的大作中提到】
: he must be looking at some steroid compounds. That's pretty established just
: like these tests in olympics.
: is there any proteinic sexual maker in the body fluid especially plasma? if
: so, how reliable can they detect it?
: I have some doubts.
: PS: I just got some information that pregnancy test is actually looking at a protein. sorry for my ignorance.
:
: even
|
