c*********r
发帖数: 1312 | 1 Sea Urchin Meeting归来，收获很多，先写一些印象深刻的吧。
【转自biowsnv.com】
1. 会议名字叫做Developmental Biology of the Sea Urchin，每一年半在Wools Hole
的MBL开一次，至今第20届，推来有30年的历史了。名字叫做Sea Urchin Meeting，其
实参加会议的还有很多做各种海洋生物的研究者。做海胆的目前没有中国大陆的PI，台
湾的前不久有了一个，日本和欧洲的不少，主要的还是北美的。北美大多数都是Eric
Davidson和David McClay的徒子徒孙们。这两位都年过七旬，会上给David McClay搞了
个简短的70岁庆祝。David每天跑步5英里，看起来就是五十多岁的样子。他亲自做实验
，micromere transfer做得是炉火纯青。Eric年纪更大些，据说因为得病，腿脚不好，
传说腿脚利索时还亲自潜水下海捞海胆。这两人自然都是大牛，文章灌水就不多说了，
Eric更是奠定了gene regulatory network的发展。当然据我老板说，最早的gene
regulatory network是建立在他的工作基础上的。
2. 上一届最火的话题是gene regulatory network，这一届更火的是Next-Generation
Sequencing。
3. 又看到了那句经典的：“It is not birth, marriage, or death, but
gastrulation which is truly the most important time in your life.” 最后会议
的龙虾聚餐后，更是颁发了一个Best Anus的奖，奖给会议上一位幽默的老学者在PPT中
展示一个漂亮的胚孔。（海胆，包括人胚孔最终是发育成肠道的开口。。。）
4. 提到这句话时，是在纪念John B. Morrill的离去。EvoDevo的大牛Mark Martindale
写了一封信来纪念他，读来让人感到一个值得尊敬的科学工作者的平凡和美丽。把信贴
在这里，供有心的同学一读。
When I first met John Morrill, and the reason I wound-up at New College in
the first place, I had what people called, “a problem with authority”. He
had probably seen hundreds of kids like me. I knew I was not the sharpest
tool in the shed, but for some reason he thought I was creative and stubborn
enough not to have to do things the same way everybody else did. He took my
rebellious spirit, passion and natural sense of curiosity and taught me
that there was a socially acceptable outlet for all that angst and it was
called critical thinking.
I have compared notes with many of John’s students over the years and most
of us had similar experiences. He taught us to trust our hands and believe
what we see. He taught us to be independent and take personable
responsibility for our ideas, education, and actions. He taught us the joy
of thinking of new ideas, making educated guesses and following them through
. He taught us that everything was wrong until proven right, but that
nothing (and nobody) was ever right because you could only prove things
wrong, and that if we could not figure out a way to deal with this, we
should find a different profession. He taught us that any argument is only
as strong as the assumptions underlying it, and that we could save ourselves
a lot of time by just starting there. He taught us that making progress by
chipping away at all the big problems is as valuable as trying to tackle
things all at once and never having anything to show for it. He taught us
that science is done by people, all kinds of different people, and that when
you find kindred spirits (like the four Qs) you should work together
because, like everything in biology (life), “the whole is more than the sum
of the parts”. He did this all without us even knowing what he was doing.
He never lectured “at” us or took credit for anything he had done. He let
us open our own doors and let us take the first steps through to the other
side.
It is obvious to me that I would never have become a scientist if I had not
taken that first cell biology class with John in my second year at New
College. I did not even know what a scientist was or that there was a way to
make a living doing it. And at the time I didn’t care. He taught me to
love the ‘process’ of doing science, to learn for learning’s sake, and I
never expected anything more out of it. It has been a long string of minor
miracles and plenty of luck that has me here today, and it certainly would
never have happened if John had not recognized something and kicked me
through that door. Thanks, John. I will be looking for you when I get to the
other side.
Mark Q. Martindale
New College 1977-1981
Professor and Director
Kewalo Marine Lab
Pacific Biosciences Research Center
University of Hawaii
John在我看来，并非师出豪门，最终也只是在一个college做faculty，但他的工作太美
丽了！他把海胆胚胎各个时期的电镜照片汇集成册，无偿分享，让人感受到胚胎发育的
美丽和奇妙。对John的敬仰之心也悠然而生。
先写到这里吧，改天有空的话研究一下如何分享这些照片。最后贴一张张牙舞爪的龙虾
，祝大家好运。^_^
【转自biowsnv.com】 |
c********r
发帖数: 189 | |
s******y
发帖数: 28562 | 3 今年的龙虾怎么这么大？还是你们故意挑了一个大的来照像？
【在 c********r 的大作中提到】
: 这个必须顶，你这个龙虾要是能打包就好了，哈哈
|
c*********r
发帖数: 1312 | 4 这个是平均水平吧。每个几乎都这么大。在水族馆里看到长到这个大小要好几年呢。。。
【在 s******y 的大作中提到】
: 今年的龙虾怎么这么大？还是你们故意挑了一个大的来照像？
|
s******y
发帖数: 28562 | 5 说到海胆，我最深的印象就是我们老板告诉我她当年做博士后的时候，
走在沙滩上一边采标本一边吃，害得我一直好奇海胆卵到底好不好吃。 |
s******y
发帖数: 28562 | 6 我都忘记是不是真的就那么大了：）
就光记得肚子里的肉真好吃。
。。
【在 c*********r 的大作中提到】
: 这个是平均水平吧。每个几乎都这么大。在水族馆里看到长到这个大小要好几年呢。。。
|
c*********r
发帖数: 1312 | 7 海胆的整个gonad都可以吃。不过我目前只吃过生的egg。。。咸咸的，creamy。。。
【在 s******y 的大作中提到】
: 说到海胆，我最深的印象就是我们老板告诉我她当年做博士后的时候，
: 走在沙滩上一边采标本一边吃，害得我一直好奇海胆卵到底好不好吃。
|
c*********r
发帖数: 1312 | 8 螯里的肉更有嚼劲。据说wools hole南边的Vineyard island上的龙虾更大。。。
【在 s******y 的大作中提到】
: 我都忘记是不是真的就那么大了：）
: 就光记得肚子里的肉真好吃。
:
: 。。
|
g****1
发帖数: 261 | 9
Sea Urchin (aka Uni) is delicious and much more expensive than lobster
now. BTW, that lobster looks smaller than before.
【在 c*********r 的大作中提到】
: 海胆的整个gonad都可以吃。不过我目前只吃过生的egg。。。咸咸的，creamy。。。
|
s******y
发帖数: 28562 | 10 爪子里的肉没有味道，比螃蟹爪子差多了
【在 c*********r 的大作中提到】
: 螯里的肉更有嚼劲。据说wools hole南边的Vineyard island上的龙虾更大。。。
|
|
|
s******y
发帖数: 28562 | 11 你们实验室有这个可以吃么？听得我都馋了
【在 c*********r 的大作中提到】
: 海胆的整个gonad都可以吃。不过我目前只吃过生的egg。。。咸咸的，creamy。。。
|
c*********r
发帖数: 1312 | 12 可惜我们做的不是Uni那个species，不然早被日本博后吃光了。^_^
【在 g****1 的大作中提到】
:
: Sea Urchin (aka Uni) is delicious and much more expensive than lobster
: now. BTW, that lobster looks smaller than before.
|
c*********r
发帖数: 1312 | 13 我们实验室做的品种和Uni不一样，Uni可以卖到$450/kg。。。我们做的是加州产的紫
海胆Purpuratus。
【在 s******y 的大作中提到】
: 你们实验室有这个可以吃么？听得我都馋了
|
c*********r
发帖数: 1312 | 14 这个倒是。不过我们都是沾着加热的黄油吃，口感更好，虽然不是很健康。。。
【在 s******y 的大作中提到】
: 爪子里的肉没有味道，比螃蟹爪子差多了
|
c*********r
发帖数: 1312 | 15 你以前也去过？前辈啊。^_^
【在 g****1 的大作中提到】
:
: Sea Urchin (aka Uni) is delicious and much more expensive than lobster
: now. BTW, that lobster looks smaller than before.
|
s******y
发帖数: 28562 | 16 紫海胆能吃么？
【在 c*********r 的大作中提到】
: 我们实验室做的品种和Uni不一样，Uni可以卖到$450/kg。。。我们做的是加州产的紫
: 海胆Purpuratus。
|
c*********r
发帖数: 1312 | 17 能吃，我们曾经直接用pipette取几十微升egg吃，有待开发新的recipe。。。
【在 s******y 的大作中提到】
: 紫海胆能吃么？
|
s******y
发帖数: 28562 | 18 用Pipet 直接打到嘴里吃？
这个。。。心理有点挑战性。。。虽然明明知道应该很干净。。。
每只海胆才几十微升的蛋么？那么少啊，我还以为一拨开就满满一瓢的子呢。
【在 c*********r 的大作中提到】
: 能吃，我们曾经直接用pipette取几十微升egg吃，有待开发新的recipe。。。
|
c*********r
发帖数: 1312 | 19 几十微升的是高浓度的，我们叫dry egg。一只urchin状态好的话可以给百万个egg。
【在 s******y 的大作中提到】
: 用Pipet 直接打到嘴里吃？
: 这个。。。心理有点挑战性。。。虽然明明知道应该很干净。。。
: 每只海胆才几十微升的蛋么？那么少啊，我还以为一拨开就满满一瓢的子呢。
|
n***w
发帖数: 2405 | 20 。。。。。。。
笑趴了。。。
从未吃过海胆及其egg的飘过。。。 |
