g********0 发帖数: 6201 | 1 Federal Grant Bar for Neurologist
02/29/2012 David Pittman
A former SUNY neurology department chair has been found guilty of
fabricating data in two published papers, four grants applications, and a
submitted manuscript.
A former State University of New York (SUNY) neurobiology department chair
has been banned from conducting federally funded research for a year and
will have his work supervised for another two years. The ban is the result
of an investigation that found he falsified data in two published papers and
four grants applications submitted to the National Institutes of Health (
NIH).
Michael W. Miller, former professor and chair of the department of
neuroscience and physiology at SUNY, Upstate Medical University in Syracuse,
"engaged in research misconduct by falsifying and/or fabricating data that
were included in grant applications," according to the US Department of
Health and Human Services' Office of Research Integrity (ORI).
Miller falsified figures 4 and 6 in J. Neurochem. 2007 by altering bar
graphs to increase the significance of the effect of ethanol exposure and
withdrawal on NGF or trkA protein expression. Source: J. Neurochem
Miller's research focused on the effects of alcohol exposure during fetal
development. According to a Federal Register notice published February 27,
2012, Miller changed data to exaggerate ethanol's effect on development.
In a 2007 paper published in Journal of Neurochemistry, Miller altered bar
graphs to increase the significance of ethanol exposure to confirm his
hypothesis that alcohol exposure and withdraw affect normal brain circuits (
1). The paper was retracted last month.
Likewise, a 2009 paper published in Developmental Neuroscience contained
fabricated bar graphs that reportedly showed that ethanol exposure caused
brain damage in the brain of young mice (2). In 2010, the journal editors
contacted Miller about the unreliable data to rectify the situation. However
, after receiving additional information last year, they requested a
retraction from him. In January, honoring a request from SUNY, the journal
retracted the paper.
Furthermore, Miller submitted a manuscript to the Proceedings of the
National Academy of Sciences that supposedly contained data on an experiment
in which mice were exposed to alcohol during their early development.
However, that data was never actually generated. That same fabricated data
was also included in an NIH grant application.
On February 28, SUNY Upstate Medical University vice president of research
Steven Goodman released a statement that said the school was "deeply
disappointed by the apparent lack of regard for the integrity of scientific
discovery."
"Adherence to university policies that outline professional conduct on
matters related to research is of the utmost importance at Upstate," Goodman
said in the statement.
In 2009, the school began investigating Miller's work, interviewing
individuals associated with Miller's work and reviewing his manuscripts,
computer files, and notes. Last fall, Miller left his position at the
university. In the end, the school reported its results to the ORI.
As a result, Miller has voluntarily entered into an exclusion agreement with
the ORI. That agreement bars him from receiving a federal grant for one
year and from doing unsupervised federal research for two years after that.
Also, he is banned from any advisory role to the government for three years.
While Miller did not admit or deny wrongdoing, he conceded to the evidence
of research misconduct.
References
1. Bruns, M.B., and Miller, M.W. 2007. Functional nerve growth factor and
trkA autocrine/paracrine circuits in adult rat cortex are revealed by
episodic ethanol exposure and withdrawal. J. Neurochem. 100:1115-68.
2. Miller, M.W., and Hu, H. 2009. Lability of neuronal lineage decisions is
revealed by acute exposures to ethanol. Dev. Neurosci. 31:50-7. | f*******l 发帖数: 99 | 2 去看了他们的网站,已经找不到这个人了。可能离开了 |
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