n******7
发帖数: 12463 | 1 Resisting Arsenic
The discovery of a bacterium living in the extreme conditions of Mono Lake,
California, created a major controversy because it was claimed to be able to
grow solely on arsenic and could substitute arsenate for phosphate in its
key macromolecules, including DNA. Working with the same Halomonas spp.
bacterium, known as GFAJ-1, and ultrapure reagents, Erb et al. (p. 467,
published online 8 July) found that the bacterium needed a low level of
phosphate (1.6 μM) to grow at all. Rather than significant specific arsenic
incorporation, when the organism was grown in 40 mM arsenic, its nucleic
acids acquired a trace of arsenic. Similarly, Reaves et al. (p. 470,
published online 8 July) found that GFAJ-1 could not grow in the absence of
phosphate and, moreover, that its growth was not stimulated by the addition
of arsenate, although a trace amount of arsenic was also detected in DNA.
Thus, GFAJ-1 shows no particular facility to substitute arsenic for
phosphate, when phosphate is limiting, but it can tolerate high
concentrations of the poison while efficiently scavenging phosphate.
科研还是政治经济决定的啊 | b**********D
发帖数: 145 | 2 不是很快就打假了么
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to
arsenic
【在 n******7 的大作中提到】
: Resisting Arsenic
: The discovery of a bacterium living in the extreme conditions of Mono Lake,
: California, created a major controversy because it was claimed to be able to
: grow solely on arsenic and could substitute arsenate for phosphate in its
: key macromolecules, including DNA. Working with the same Halomonas spp.
: bacterium, known as GFAJ-1, and ultrapure reagents, Erb et al. (p. 467,
: published online 8 July) found that the bacterium needed a low level of
: phosphate (1.6 μM) to grow at all. Rather than significant specific arsenic
: incorporation, when the organism was grown in 40 mM arsenic, its nucleic
: acids acquired a trace of arsenic. Similarly, Reaves et al. (p. 470,
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