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Biology版 - 包子,求一篇文章
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相关话题的讨论汇总
话题: am话题: disease话题: cardiac
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x********e
发帖数: 2275
1
请发到:h******[email protected]
先谢过了!
Adrenomedullins: Therapeutic Potential in Cardiovascular Disease
Author: J. Charles, Christopher
Source: Current Hypertension Reviews, Volume 7, Number 4, December 2011 , pp
. 284-291(8)
Abstract:
Cardiovascular disease is a leading cause of death and disability and
despite advances in treatment there remains an ongoing need to develop new
therapeutic interventions. Accumulating evidence points towards an important
role for the adrenomedullin (AM) family of peptides in pressure/volume
homeostasis and indicate potential as therapeutic agents in a variety of
clinical settings including cardiovascular disease. Plasma levels of AM are
raised in cardiovascular disease in proportion to severity of cardiac
dysfunction and are useful prognostic indicators of outcome. AM
administration in both experimental and human heart failure induces a
beneficial spectrum of biological action including reduced arterial and
atrial pressures, improved cardiac output, inhibition of plasma aldosterone
and preservation or augmentation of urinary sodium excretion. Experimental
data also supports a role for AM in cardioprotection in cardiac ischemia/
reperfusion injury and in the progression of heart failure following
myocardial infarction. Thus, strategies to manipulate the AM system may
prove beneficial as adjunctive therapy in cardiovascular disease.
x********e
发帖数: 2275
2
Got it from the author.

pp
important

【在 x********e 的大作中提到】
: 请发到:h******[email protected]
: 先谢过了!
: Adrenomedullins: Therapeutic Potential in Cardiovascular Disease
: Author: J. Charles, Christopher
: Source: Current Hypertension Reviews, Volume 7, Number 4, December 2011 , pp
: . 284-291(8)
: Abstract:
: Cardiovascular disease is a leading cause of death and disability and
: despite advances in treatment there remains an ongoing need to develop new
: therapeutic interventions. Accumulating evidence points towards an important

1 (共1页)
进入Biology版参与讨论
相关主题
求文献:Mitochondrial Dynamics: An Emerging Paradigm in Ischemia-Reperfusion Injury求PAPER一篇,谢谢!
文献求助urgent paper help, please!
杂志审稿anyone used HL-1 cell line
paper help, thanks!paper help please
求助文献一篇包子求PAPER
paper help. Thanks!Help on animal model
paper helpDNA Transfection问题
Cardiovascular endocrinology 薄厚的职业前景怎样?求paper,有包子,谢谢。
相关话题的讨论汇总
话题: am话题: disease话题: cardiac