d****7 发帖数: 109 | 1 不知道之前有人发过没,这篇文章从进化的角度来探讨ENCODE里的数据,尤其是对“
junk dna vs garbage dna”的观点以及探讨读起来很有启发性
这篇不是research article,读起来很enjoyable
http://m.gbe.oxfordjournals.org/content/early/2013/02/20/gbe.ev
One quote from the article:
So, what have we learned from the efforts of 442 researchers consuming 288
million
dollars? According to Eric Lander, a Human Genome Project luminary, ENCODE
is the
“Google Maps of the human genome” (Durbin et al. 2010). We beg to differ,
ENCODE is
considerably worse than even Apple Maps. | c********e 发帖数: 598 | 2
,
No real interesting content.
The author is not happy abut "Big science".
【在 d****7 的大作中提到】 : 不知道之前有人发过没,这篇文章从进化的角度来探讨ENCODE里的数据,尤其是对“ : junk dna vs garbage dna”的观点以及探讨读起来很有启发性 : 这篇不是research article,读起来很enjoyable : http://m.gbe.oxfordjournals.org/content/early/2013/02/20/gbe.ev : One quote from the article: : So, what have we learned from the efforts of 442 researchers consuming 288 : million : dollars? According to Eric Lander, a Human Genome Project luminary, ENCODE : is the : “Google Maps of the human genome” (Durbin et al. 2010). We beg to differ,
| M****7 发帖数: 214 | 3 确实是一篇挺有意思的文章,谢谢分享
,
【在 d****7 的大作中提到】 : 不知道之前有人发过没,这篇文章从进化的角度来探讨ENCODE里的数据,尤其是对“ : junk dna vs garbage dna”的观点以及探讨读起来很有启发性 : 这篇不是research article,读起来很enjoyable : http://m.gbe.oxfordjournals.org/content/early/2013/02/20/gbe.ev : One quote from the article: : So, what have we learned from the efforts of 442 researchers consuming 288 : million : dollars? According to Eric Lander, a Human Genome Project luminary, ENCODE : is the : “Google Maps of the human genome” (Durbin et al. 2010). We beg to differ,
| M*P 发帖数: 6456 | 4 为什么要说"又"呢?
★ 发自iPhone App: ChineseWeb 7.8
【在 d****7 的大作中提到】 : 不知道之前有人发过没,这篇文章从进化的角度来探讨ENCODE里的数据,尤其是对“ : junk dna vs garbage dna”的观点以及探讨读起来很有启发性 : 这篇不是research article,读起来很enjoyable : http://m.gbe.oxfordjournals.org/content/early/2013/02/20/gbe.ev : One quote from the article: : So, what have we learned from the efforts of 442 researchers consuming 288 : million : dollars? According to Eric Lander, a Human Genome Project luminary, ENCODE : is the : “Google Maps of the human genome” (Durbin et al. 2010). We beg to differ,
| D****e 发帖数: 14 | 5 这篇文章好几个基本常识都错了。。
。。。A scan over all human chromosomes (22 autosomes + X + Y) reveals that
there are 150,281,981 CpG sites。。
作者到底有没有读过ENCODE那一系列的文章啊。。怎么发表的。。 | d*******s 发帖数: 24 | 6 Did you? and what's wrong?
that
【在 D****e 的大作中提到】 : 这篇文章好几个基本常识都错了。。 : 。。。A scan over all human chromosomes (22 autosomes + X + Y) reveals that : there are 150,281,981 CpG sites。。 : 作者到底有没有读过ENCODE那一系列的文章啊。。怎么发表的。。
| M*P 发帖数: 6456 | 7 这些人理论是不是under selection就没有功能。问题是很多human disease,或者是
human specific 功能就未必是under selection。
encode不用进化作为依据就是为了找到靠进化无法理解的功能片段。当然认为所有open
chromatin都是有功能的也是夸张了。
【在 d****7 的大作中提到】 : 不知道之前有人发过没,这篇文章从进化的角度来探讨ENCODE里的数据,尤其是对“ : junk dna vs garbage dna”的观点以及探讨读起来很有启发性 : 这篇不是research article,读起来很enjoyable : http://m.gbe.oxfordjournals.org/content/early/2013/02/20/gbe.ev : One quote from the article: : So, what have we learned from the efforts of 442 researchers consuming 288 : million : dollars? According to Eric Lander, a Human Genome Project luminary, ENCODE : is the : “Google Maps of the human genome” (Durbin et al. 2010). We beg to differ,
| P****d 发帖数: 564 | 8 到底什么是function?白马和马真的不是一个概念,无论内涵还是外延,都不一样。真
的。 |
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