p*****e
发帖数: 560 | 1 有没有哪个网站可以查到transmembrane protein，比如TGFBR1，哪些序列是intracell
ular的，哪些是extracellular的？ | s******9
发帖数: 283 | 2 NCBI protein database一般都有标注吧。
FEATURES Location/Qualifiers
source 1..503
/organism="Homo sapiens"
/db_xref="taxon:9606"
gene 1..503
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
Protein 1..503
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/product="TGF-beta receptor type-1"
/EC_number="2.7.11.30"
/note="TGFR-1; Activin A receptor type II-like protein
kinase of 53kD; Activin receptor-like kinase 5;
Serine/threonine-protein kinase receptor R4; TGF-beta
type
I receptor; Transforming growth factor-beta receptor
type
I; ALK-5; ALK5; SKR4; TGF-beta receptor type I; TbetaR-
I"
/UniProtKB_evidence="Evidence at protein level"
Region 1..33
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Signal"
/experiment="experimental evidence, no additional
details
recorded"
Region 24..26
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="Missing (in allele TGFBR1*6A; could be a tumor
susceptibility allele). /FTId=VAR_022342."
Region 26
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="A -> AA (in allele TGFBR1*10A; rare polymorphism
).
/FTId=VAR_022343."
Region 34..503
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Mature chain"
/experiment="experimental evidence, no additional
details
recorded"
/note="TGF-beta receptor type-1. /FTId=PRO_0000024423."
Region 34..126
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Topological domain"
/inference="non-experimental evidence, no additional
details recorded"
/note="Extracellular (Potential)."
Region 35..114
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Activin_recp"
/note="Activin types I and II receptor domain;
pfam01064"
/db_xref="CDD:189827"
Region 35..37
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Bond bond(36,54)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/bond_type="disulfide"
/experiment="experimental evidence, no additional
details
recorded"
Bond bond(38,41)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/bond_type="disulfide"
/experiment="experimental evidence, no additional
details
recorded"
Region 41
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="C -> Y (in MSSE; hypomorphic mutation).
/FTId=VAR_065826."
Region 42..46
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Hydrogen bonded turn"
/experiment="experimental evidence, no additional
details
recorded"
Region 45
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="N -> S (in MSSE; hypomorphic mutation).
/FTId=VAR_065827."
Site 45
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="glycosylation"
/inference="non-experimental evidence, no additional
details recorded"
/note="N-linked (GlcNAc...) (Potential)."
Bond bond(48,71)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/bond_type="disulfide"
/experiment="experimental evidence, no additional
details
recorded"
Region 51..57
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 52
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="G -> R (in MSSE; hypomorphic mutation).
/FTId=VAR_065828."
Region 61..63
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 69..72
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 74..76
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Hydrogen bonded turn"
/experiment="experimental evidence, no additional
details
recorded"
Region 77..82
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 83
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="P -> L (in MSSE; hypomorphic mutation).
/FTId=VAR_065829."
Region 84..86
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Hydrogen bonded turn"
/experiment="experimental evidence, no additional
details
recorded"
Bond bond(86,100)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/bond_type="disulfide"
/experiment="experimental evidence, no additional
details
recorded"
Region 89..92
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 94..101
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Bond bond(101,106)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/bond_type="disulfide"
/experiment="experimental evidence, no additional
details
recorded"
Region 102..105
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 107..109
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 114
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Splicing variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="T -> TGPFS (in isoform 2). /FTId=VSP_041326."
Region 115..191
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Splicing variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="Missing (in isoform 3). /FTId=VSP_041327."
Region 127..147
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Transmembrane region"
/inference="non-experimental evidence, no additional
details recorded"
/note="Helical; (Potential)."
Region 139
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="I -> V. /FTId=VAR_054160."
Region 148..503
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Topological domain"
/inference="non-experimental evidence, no additional
details recorded"
/note="Cytoplasmic (Potential)."
Region 153
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="V -> I (in dbSNP:rs56014374). /FTId=VAR_041412."
Site 165
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="modified"
/experiment="experimental evidence, no additional
details
recorded"
/note="Phosphoserine."
Region 175..204
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Domain"
/experiment="experimental evidence, no additional
details
recorded"
/note="GS."
Region 175..203
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="TGF_beta_GS"
/note="Transforming growth factor beta type I GS-motif;
pfam08515"
/db_xref="CDD:149535"
Region 177..183
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Site 185..186
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="TT->VV: Loss of phosphorylation on threonine
residues. Loss of threonine phosphorylation, reduced
phosphorylation on serine residues and loss of response
to
TGF-beta; when associated with A-187; A-189 and A-191."
Site 185
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="modified"
/experiment="experimental evidence, no additional
details
recorded"
/note="Phosphothreonine; by TGFBR2."
Site 186
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="modified"
/experiment="experimental evidence, no additional
details
recorded"
/note="Phosphothreonine; by TGFBR2."
Region 187..190
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Site 187
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="modified"
/experiment="experimental evidence, no additional
details
recorded"
/note="Phosphoserine; by TGFBR2."
Site 187
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="S->A: Loss of threonine phosphorylation, reduced
phosphorylation on serine residues and loss of response
to
TGF-beta; when associated with 185-VV-186; A-189 and
A-191."
Site 189
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="modified"
/experiment="experimental evidence, no additional
details
recorded"
/note="Phosphoserine; by TGFBR2."
Site 189
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="S->A: Loss of threonine phosphorylation, reduced
phosphorylation on serine residues and loss of response
to
TGF-beta; when associated with 185-VV-186; A-187 and
A-191."
Region 191..193
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Site 191
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="modified"
/experiment="experimental evidence, no additional
details
recorded"
/note="Phosphoserine; by TGFBR2."
Site 191
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="S->A: Loss of threonine phosphorylation, reduced
phosphorylation on serine residues and loss of response
to
TGF-beta; when associated with 185-VV-186; A-187 and
A-189."
Region 193..194
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Short sequence motif of biological
interest"
/experiment="experimental evidence, no additional
details
recorded"
/note="FKBP1A-binding."
Site 193
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="L->G: Loss of interaction with FKBP1A."
Site 194
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="P->K: Loss of interaction with FKBP1A."
Region 200
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="T -> I (in LDS1A). /FTId=VAR_022344."
Site 200
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="T->D: Loss of response to TGF-beta."
Site 200
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="T->V: Loss of phosphorylation. Loss of response
to
TGF-beta."
Region 202..204
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Site 204
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="T->D: Constitutive activation."
Site 204
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="mutagenized"
/experiment="experimental evidence, no additional
details
recorded"
/note="T->V: Reduced phosphorylation. Reduced response
to
TGF-beta."
Region 205..495
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Domain"
/experiment="experimental evidence, no additional
details
recorded"
/note="Protein kinase."
Region 205..490
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Pkinase"
/note="Protein kinase domain; pfam00069"
/db_xref="CDD:200973"
Region 205..213
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 211..411
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="PKc"
/note="Catalytic domain of Protein Kinases; cd00180"
/db_xref="CDD:173623"
Site order(211..215,219,230,232,260,280..283,287,289,333,335,
337..338,340,351,354,374..377)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="active"
/db_xref="CDD:173623"
Site order(211..215,219,230,232,260,280..283,287,333,335,
337..338,340,351)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="other"
/note="ATP binding site [chemical binding]"
/db_xref="CDD:173623"
Site 211..219
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="np-binding"
/inference="non-experimental evidence, no additional
details recorded"
/note="ATP (By similarity)."
Site order(215,287,289,333,335,337,354,374..377)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="other"
/note="substrate binding site [chemical binding]"
/db_xref="CDD:173623"
Region 215..224
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 227..234
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 232
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="K -> E (in LDS2A). /FTId=VAR_029481."
Site 232
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="binding"
/inference="non-experimental evidence, no additional
details recorded"
/note="ATP (By similarity)."
Region 236..238
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 239..249
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 241
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="S -> L (in LDS1A). /FTId=VAR_029482."
Region 251..253
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 262..269
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 266
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="D -> Y (in LDS1A). /FTId=VAR_066720."
Region 267
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="N -> H (in a patient with Marfan syndrome).
/FTId=VAR_029483."
Region 271..281
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 288..294
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 291
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="Y -> C (in dbSNP:rs35974499). /FTId=VAR_041413."
Region 299..317
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 318
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="M -> R (in LDS1A). /FTId=VAR_022345."
Region 322..324
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 328..330
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region <331..495
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="PKc_like"
/note="Protein Kinases, catalytic domain; cl09925"
/db_xref="CDD:213116"
Site order(333,335,337,354,373..376)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="other"
/note="substrate binding site [chemical binding]"
/db_xref="CDD:173623"
Site 333
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="active"
/inference="non-experimental evidence, no additional
details recorded"
/note="Proton acceptor (By similarity)."
Region 338..341
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 347..349
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Site order(350..356,374..377)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="other"
/note="activation loop (A-loop)"
/db_xref="CDD:173623"
Site order(350..355,373..376)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/site_type="other"
/note="activation loop (A-loop)"
/db_xref="CDD:173623"
Region 351
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="D -> G (in LDS1A). /FTId=VAR_066721."
Region 352..354
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 356..359
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 360..363
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Hydrogen bonded turn"
/experiment="experimental evidence, no additional
details
recorded"
Region 364..366
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 375
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="T -> I (in LDS1A). /FTId=VAR_066722."
Region 376..378
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 381..384
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Bond bond(391)
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/bond_type="xlink"
/inference="non-experimental evidence, no additional
details recorded"
/note="Glycyl lysine isopeptide (Lys-Gly) (interchain
with
G-Cter in SUMO) (By similarity)."
Region 393..413
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 400
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="D -> G (in LDS1A). /FTId=VAR_022346."
Region 417..419
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Beta-strand region"
/experiment="experimental evidence, no additional
details
recorded"
Region 427..431
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Hydrogen bonded turn"
/experiment="experimental evidence, no additional
details
recorded"
Region 438..445
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 456..459
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 462..472
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 479..481
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 485..497
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Helical region"
/experiment="experimental evidence, no additional
details
recorded"
Region 487
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="R -> P (in LDS1A and LDS2A). /FTId=VAR_022347."
Region 487
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="R -> Q (in LDS1A and LDS2A). /FTId=VAR_029484."
Region 487
/gene="TGFBR1"
/gene_synonym="ALK5"
/gene_synonym="SKR4"
/region_name="Variant"
/experiment="experimental evidence, no additional
details
recorded"
/note="R -> W (in LDS2A). /FTId=VAR_029485."
ORIGIN
1 meaavaaprp rllllvlaaa aaaaaallpg atalqcfchl ctkdnftcvt dglcfvsvte
61 ttdkvihnsm ciaeidlipr drpfvcapss ktgsvtttyc cnqdhcnkie lpttvksspg
121 lgpvelaavi agpvcfvcis lmlmvyichn rtvihhrvpn eedpsldrpf isegttlkdl
181 iydmttsgsg sglpllvqrt iartivlqes igkgrfgevw rgkwrgeeva vkifssreer
241 swfreaeiyq tvmlrhenil gfiaadnkdn gtwtqlwlvs dyhehgslfd ylnrytvtve
301 gmiklalsta sglahlhmei vgtqgkpaia hrdlksknil vkkngtccia dlglavrhds
361 atdtidiapn hrvgtkryma pevlddsinm khfesfkrad iyamglvfwe iarrcsiggi
421 hedyqlpyyd lvpsdpsvee mrkvvceqkl rpnipnrwqs cealrvmaki mrecwyanga
481 arltalrikk tlsqlsqqeg ikm | p*****e
发帖数: 560 | 3 多谢！
【在 s******9 的大作中提到】
: NCBI protein database一般都有标注吧。
: FEATURES Location/Qualifiers
: source 1..503
: /organism="Homo sapiens"
: /db_xref="taxon:9606"
: gene 1..503
: /gene="TGFBR1"
: /gene_synonym="ALK5"
: /gene_synonym="SKR4"
: Protein 1..503
| j****n
发帖数: 3370 | 4 HMMTOP
www.enzim.hu/hmmtop/
intracell
★ 发自iPhone App: ChineseWeb 7.8
【在 p*****e 的大作中提到】
: 有没有哪个网站可以查到transmembrane protein，比如TGFBR1，哪些序列是intracell
: ular的，哪些是extracellular的？
|
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