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发帖数: 72 | 1 需要刺激人的cd4 T细胞，需要合成一个多肽，loading 到MHC II分子上。需和合成这
么几种多肽中一种：
Fibrinogen-α (P02671) 78 to 91， Aggrecan (P16112) 84 to 103， Vimentin 66
to 78 , Collagen II (P02458) 1,236 to 1,249 以及 CLIP, CD74,(P04233)
Invariant chain 106-120。请问哪种能 most commonly recognized amongst healthy
donors MHC-II DR1 or DR4?
thanks a lot.. | c**********n
发帖数: 177 | 2 http://tetramer.yerkes.emory.edu/
Check this facility，I think they can make both DR1 and DR4 loaded with
desired peptide.
If you are wondering how good the peptide can be loaded on the MHC, you can
check
whether the peptide contains the docking residues for the MHC. |
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