D*a
发帖数: 6830 | 1 http://www.sciencedirect.com/science/article/pii/S0092867414012
Here, we report a scalable differentiation protocol that can generate
hundreds of millions of glucose-responsive β cells from hPSC in vitro.
These stem-cell-derived β cells (SC-β) express markers found in mature β
cells, flux Ca2+ in response to glucose, package insulin into secretory
granules, and secrete quantities of insulin comparable to adult β cells in
response to multiple sequential glucose challenges in vitro. | B******o
发帖数: 496 | 2 他挖的坑挺多的，是不是真的还得别家confirm才行。
β
in
【在 D*a 的大作中提到】
: http://www.sciencedirect.com/science/article/pii/S0092867414012
: Here, we report a scalable differentiation protocol that can generate
: hundreds of millions of glucose-responsive β cells from hPSC in vitro.
: These stem-cell-derived β cells (SC-β) express markers found in mature β
: cells, flux Ca2+ in response to glucose, package insulin into secretory
: granules, and secrete quantities of insulin comparable to adult β cells in
: response to multiple sequential glucose challenges in vitro.
| l*****7
发帖数: 8463 | 3 如果是真的， 那么将是个大进展！ 里程碑！
β
in
【在 D*a 的大作中提到】
: http://www.sciencedirect.com/science/article/pii/S0092867414012
: Here, we report a scalable differentiation protocol that can generate
: hundreds of millions of glucose-responsive β cells from hPSC in vitro.
: These stem-cell-derived β cells (SC-β) express markers found in mature β
: cells, flux Ca2+ in response to glucose, package insulin into secretory
: granules, and secrete quantities of insulin comparable to adult β cells in
: response to multiple sequential glucose challenges in vitro.
| b****r
发帖数: 17995 | | D*a
发帖数: 6830 | 5 以前的都是insulin positive cells，这个是“真的”
【在 b****r 的大作中提到】
: 我都听过几个人声称自己分化了beta细胞了
| d**********t
发帖数: 20415 | 6 以前那些是无法response to glucose的非成熟细胞吧，需要打到动物体内才能成熟的
【在 b****r 的大作中提到】
: 我都听过几个人声称自己分化了beta细胞了
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