s*****r 发帖数: 223 | 1 想写段程序去预测蛋白的跨膜区和非跨膜区, 想知道至少几个氨基酸才能横穿细胞膜?
if a hydrophobic region cross the fatty cell membrane, 那这个hydrophobic
region 至少要多少个 aa?
相对的
hydrophilic segments that touch the watery cytoplasm and extracellular
environments,
这个 hydrophilic segment 至少是几个aa?
谢谢。
最好有文章可以引用下(或者能告诉我点信息, 我自己查) | i***l 发帖数: 1656 | 2 depends on alpha helix or beta sheet
roughly, ~20 aa for the former and ~12 for the latter, may not be very
accurate though
you can go to RSCB find some examples and take the mean value
no matter hydrophobic or hydrophilic, my 2 cents
膜?
【在 s*****r 的大作中提到】![](/moin_static193/solenoid/img/up.png) : 想写段程序去预测蛋白的跨膜区和非跨膜区, 想知道至少几个氨基酸才能横穿细胞膜? : if a hydrophobic region cross the fatty cell membrane, 那这个hydrophobic : region 至少要多少个 aa? : 相对的 : hydrophilic segments that touch the watery cytoplasm and extracellular : environments, : 这个 hydrophilic segment 至少是几个aa? : 谢谢。 : 最好有文章可以引用下(或者能告诉我点信息, 我自己查)
| s*****r 发帖数: 223 | 3 谢谢, 很有用。 试了下, 12在我的模型里工作。
【在 i***l 的大作中提到】![](/moin_static193/solenoid/img/up.png) : depends on alpha helix or beta sheet : roughly, ~20 aa for the former and ~12 for the latter, may not be very : accurate though : you can go to RSCB find some examples and take the mean value : no matter hydrophobic or hydrophilic, my 2 cents : : 膜?
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