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发帖数: 18160 | 1 Postdoctoral position available in Dr. Jiang Zhu’s laboratory for highly
motivated candidates who are interested in vaccine development for viral (
HIV, HCV, Ebola, RSV, Flu, and Coronavirus) and non-viral (malaria and
tuberculosis) pathogens. Postdoctoral salary is in the range of $54,000 to $
60,000 depending on prior research experience and qualifications.
Dr. Zhu holds a joint appointment in the Department of Integrative
Structural and Computational Biology (ISCB) and the Department of Immunology
and Microbiology at Scripps Research in La Jolla, CA https://www.scripps.
edu/). Dr. Zhu is also an Adjunct Associate Professor at Texas Biomedical
Research Institute (Southwest National Primate Research Center). Details of
Dr. Zhu’s laboratory, on-going research projects, and recent publications
can be found at https://www.jzhulab.org/.
Research projects may involve, but are not limited to, (1) virology:
infections and diseases caused by RSV, HIV, Ebola, and Coronavirus; (2)
vaccine delivery: development of mRNA vaccines and viral vector-based
vaccines; (3) structural biology: crystallographic and electron microscopic
analyses of antibody/antigen complexes; and (4) immunology: immunological
analysis of vaccine-induced response in animal models and humans.
Successful candidates will have a recent Ph.D. in virology, microbiology,
immunology, structural biology, or other related fields. Candidates with
prior research experience in RSV, HIV, and Ebola vaccines are especially
encouraged to apply.
Interested applicants should send the following materials in an application
packet, preferably as a single PDF file, by email to Dr. Jiang Zhu ([email protected]
scripps.edu):
Cover letter indicating current and future research interests,
Expected starting date
Curriculum vitae
Brief summary of previous research experience (2-3 pages)
Names and contact information for 3 references
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The Leibniz Institute for Natural Product Research and Infection Biology –
Hans Knöll Institute – (Leibniz-HKI, www.leibniz-hki.de) investigates
the pathobiology of human-pathogenic fungi and identifies targets for the
development of novel natural product-based antibiotics.
The Research Group Systems Biology and Bioinformatics invites talented and
highly gifted candidates to apply for a
Postdoctoral Researcher (f/div/m) in Bioinformatics
for 2 years initially with a possibility of extension.
The Systems Biology & Bioinformatics (SBI) group of the Leibniz Institute
for Natural Product Research and Infection Biology, Hans Knöll
Institute (HKI), Jena, Germany, is seeking a Postdoctoral researcher in the
area of multi-omics integration to develop novel therapeutic treatments for
infectious diseases. SBI is an active participant in several national and
international collaborations aiming to tackle infectious diseases. The
successful candidate will work on the identification of host biomarker
signatures that can enable early diagnosis of infection and sepsis, and that
can trigger early pre-symptomatic treatment. Appropriate subsets of sepsis
patients to target with novel therapies will be identified and combinatorial
therapies will be designed and validated in preclinical and clinical
studies. The successful candidate will work closely with wet-lab scientists
and clinicians to discover new molecular mechanisms of pathogens.
Your profile:
PhD degree in Systems Biology, Computational Biology, Bioinformatics,
Biophysics, Computer Science or a related discipline
Knowledge and experience in the analysis of biological high-throughput data
Knowledge in statistical methods in the context of biological systems
Programming experience (Python, Perl, C++, R)
Well-developed collaborative skills
A strong interest in conducting collaborative research on the topic outlined
above is paramount. Candidates are expected to be interested in working at
the boundaries of several research domains.
We offer:
The successful candidates will be hosted at HKI′s SBI group. We offer an
international and multi-disciplinary environment with a strong expertise in
the proposed research field and a convivial working atmosphere in an
interdisciplinary and international research environment. Currently the
group consists of approximately 15 members at different levels of seniority.
SBI is currently coordinating a Marie Curie ITN Horizon 2020 Research and
Innovation Programme and is an active participant of the Cluster of
Excellence "Balance of the Microverse" and CRC / Transregio 124 "Pathogenic
fungi and their human host: Networks of interaction" funded by the Deutsche
Forschungsgemeinschaft. More information on the research output of the group
can be found here.
Life in Jena:
Jena is a city with high quality of life, central for trips to major cities
(Weimar, Leipzig, Dresden, Berlin, Munich) and surrounded by beautiful
nature, perfect for hiking, biking and winter sports.
Jena was awarded the title "City of Science" from the Stifterverband für
die Deutsche Wissenschaft in 2008.
The city is also a hub for notable life science companies, enabling the
transfer from academia to industry.
Salary is paid according to German TV-L (salary agreement for public service
employees). As an equal opportunity employer, the Leibniz-HKI is committed
to increasing the percentage of female scientists and therefore especially
encourages them to apply.
Applications:
Complete applications in English should include a cover letter, a CV
containing a complete list of publications, a brief statement of research
experiences, the addresses of two possible referees, and should be submitted
by July 2, 2020, via the Leibniz-HKI online application system.
https://jobs.hki-jena.de/jobs/Post-Doctoral-Researcher-fdivm-in-
Bioinformatics-eng-f244.htmlc
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The Haber lab is a new research group in the Department of Environmental
Health at HSPH. The group investigates the effect of environmental exposures
on the airways of mammalian lungs, focusing on the role of the airway
epithelium in the pathogenesis of asthma. Work in the lab involves
development and application of computational approaches for analysis and
interpretation of next-generation sequencing data, particularly single-cell
RNA-sequencing and related approaches.
We analyze clinical samples and mouse models of airway injury, inflammation
and regeneration, collaborating closely with clinical pulmonologists and
immunologists to study regulatory mechanisms underlying both tissue
homeostasis and disease pathogenesis. Environmental triggers of asthma
stimulate pathogenic networks of inflammatory signaling involving diverse
interactions amongst epithelial, immune, neuronal and stromal cells. The lab
works on developing the algorithms and analytical tools to model and
understand these tissue-wide networks underlying allergic and non-allergic
inflammation in asthma.
In addition to identifying biological mechanisms affecting respiratory
health, the group is also interested in geospatial mapping of asthma burden
using analysis of epidemiologic data. This line of research in the lab seeks
to isolate factors, such as poor housing conditions, in the social,
physical, and built environment that contribute to racial and socioeconomic
disparities in rates of asthma.
Fellows will be encouraged to take advantage of the rich and varied training
and career development opportunities offered at HSPH. If interested please
contact Dr. Haber ([email protected]).
Qualifications:
A PhD or equivalent in computational biology, computer science, statistics,
mathematics or another quantitative field. Candidates holding a degree in
biological/medical science are also welcome to apply if they have extensive
background in computational or statistical work.
Applicants must have substantial experience with genomics, epidemiologic or
other statistical data analysis. Preference will be given to candidates with
demonstrated research interests in relevant areas, particularly asthma,
COPD, lung biology and mucosal immunology.
Special Instructions
Please send curriculum vitae, names and contact information of three
references, and a brief statement of goals to: [email protected]
Online App. Form:
https://academicpositions.harvard.edu/postings/9417
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Postdoctoral Fellow - Physiology and Pharmacology (14910)
The Department of Physiology and Pharmacology in the West Virginia
University School of Medicine is seeking applications for a Postdoctoral
Fellow. This position is responsible for a translational project to
elucidate the role of environmental exposures and innate immune signaling in
lung injury and repair. Current research is focused on the understanding of
molecular and cellular basis of pulmonary disease susceptibility after
inhalation exposures to environmental stressors (xenobiotic particles and
gases). For further information about the scientific details and duties or
responsibilities please visit the lab website at: https://hussainlab.org/
Qualifications
PhD in toxicology, cell and molecular biology, immunology, developmental
biology, regenerative medicine, or a relevant biomedical field is required.
One to two years of hands on experience in animal models of pulmonary
diseases and/or cell culture techniques is required. This experience is
typically acquired through the course of doctoral training.
Salary will be based upon experience and NIH salary levels.
To Apply
Please submit your 1) cover letter, 2) current CV, and 3) contact
information for three references at https://wvu.taleo.net/careersection/
staff/jobdetail.ftl?job=14910&tz=GMT-04%3A00&tzname=
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We are looking for highly motivated candidates with a Ph.D. within last
three years in cellular and molecular immunology with an emphasis on the
cancer immunology preferred. The Zhang laboratory functions as an integrated
translational research program with the goal of designing and developing
new immunotherapies and immunologic strategies for cancer treatment. The NCI
-funded project is focused on dissecting the molecular mechanisms used for
tumor immune evasion based on the cutting-edge technical platforms including
CyTOF, Multiplex imaging and Single-cell Seq, etc.
The successful applicants should have a proven academic publication track
record, including first-authored publications at high profile journals, as
well as excellent scientific, organizational, record-keeping, problem-
solving skills. The candidates will conduct independent research by
characterizing the immune phenotypes of the genetically modified mice and/or
human specimen using cellular and molecular immunological approaches
including genome-wide gene/protein profiling analysis. The candidates are
also encouraged to explore new research areas and seek independent funding
as part of their own career development.
Please send a curriculum vitae, a brief cover letter summarizing current
research and career goals, and the names and contact information of 2-3
references to: Email: [email protected]
Bin Zhang M.D. Ph.D.
Professor
Department of Medicine –Division of Hematology/Oncology
Department of Microbiology-Immunology
Co-Director, Immune Assessment Core Facility, Robert H. Lurie Comprehensive
Cancer Center
Northwestern University Feinberg School of Medicine
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The Herbert Irving Comprehensive Cancer Center (HICCC) at Columbia
University is seeking a talented Postdoctoral Research Scientist with a PhD
trained in genetic and epigenetic profiling using NGS. The lab specializes
in liver biology, with a particular focus on using complementary model
systems to study molecular mechanisms underlying cholestatic liver diseases,
including zebrafish, mouse and in vitro cell culture systems. Research
focus will be on elucidating the mechanisms driving cellular heterogeneity
within cholangiocytes and how cell-type specific characteristics determine
cellular behavior and disease phenotype. Studies will include cell isolation
, traditional molecular techniques and assays, gene editing using CRISPR-
CAS9, RNA-Seq, Epigenetic profiling, bioinformatics using both in vitro
systems and whole animal models. Studies will include cell isolation,
traditional molecular techniques and assays, gene editing using CRISPR-CAS9,
RNA-Seq, Epigenetic profiling, bioinformatics using both in vitro systems
and whole animal models. Visit the website: http://www.zhaolabcolumbia.org/
Minimum Degree Required:
• Ph.D, MD, or equivalent doctoral degree
Minimum Qualifications:
• Excellent experimental and analytic skills and willingness to learn
new model system and methodologies
• Self-motivated with strong interest in studying the mechanistic and
translational aspects of liver diseases
• Effective communication and writing skills and record of publication
in peer-reviewed journal (s)
Ability to work independently and collaboratively
Preferred Qualifications:
• Experience in genetic and epigenetic profiling using NGS
• Prior experience with disease modeling using mammalian models or in
vitro systems and experience in NGS and bioinformatics
How to apply:
All candidates must apply through Columbia University’s RAPS online
employment application system under Requisition Number: 00001401.
Please use the following link to apply:
https://pa334.peopleadmin.com/postings/5043
The salary of the position will be competitive based on qualifications.
Applicants should send a CV, a brief statement of interest, and contact
information for three references.
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Two postdoctoral positions are immediately available in Dr. Lin Han’s
NanoBiomechanics Laboratory at the School of Biomedical Engineering, Science
and Health Systems at Drexel University. Our lab studies the roles of
regulatory collagens and proteoglycans in mechanotransduction,
musculoskeletal disease and regeneration. We utilize in vitro cell culture,
in vivo transgenic animal models, novel biomimetic and biological
nanomaterials, in combination with atomic force microscopy-based
nanomechanical tools to integrate basic and translational studies (https://
linhanlab.com). The long- term goal is to develop new matrix molecule-based
biomaterials for musculoskeletal disease treatment and tissue regeneration.
Active projects include:
1) Collagen V in mediating progenitor cell fate and mechanotransduction in
temporomandibular joint (TMJ) regeneration. The goal is to understand the
impact of the primitive regulatory collagen, type V, in regulating the
quiescence and chondrogenesis of progenitor cell in vivo and in vitro, and
to test the therapeutic potential of using collagen V for improving the
regeneration of TMJ condylar cartilage, a unique hybrid of fibro- and
hyaline cartilage.
2) Proteoglycan-based biomaterials for stem cell chondrogenesis and neo-
matrix production. The goal is to test the therapeutic potential of using
native proteoglycans (e.g., aggrecan, decorin) to modulate chondrogenic bone
marrow stromal cells chondrogenesis, mechanotransduction, as well as the
biosynthesis and assembly of neo-cartilage matrix.
Both projects offer the opportunities for developing novel biomaterials that
can have significant translational impacts on musculoskeletal regenerative
medicine. As the postdoc mentor, Dr. Han will provide support for career
goals, including training in critical and independent thinking,
grantsmanship, and providing network opportunities in the broad Biomed
community.
Qualifications
Creative, highly motivated individuals with a PhD in a relevant area (
biomaterials, musculoskeletal bioengineering, cartilage biology/
mechanobiology or related disciplines), are encouraged to apply. Experience
with cell culture, biomaterials, histology/immunohistochemistry, murine
model handling, and mechanobiological assays is a plus.
About Drexel School of Biomed
Drexel University and the School of Biomedical Engineering, Science, and
Health Systems have a strong history of research and innovation in
biomechanics, regenerative medicine, neuroengineering and drug delivery.
There is strong support for medical technology commercialization through the
endowed Coulter-Drexel Translational Research Partnership Program.
To Apply
Please submit a cover letter, CV with detailed research experience and
contact information of three references to Dr. Lin Han via email at [email protected]
drexel.edu
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