m****d 发帖数: 156 | | b*******e 发帖数: 67 | 2 is it E?
【在 m****d 的大作中提到】 : 完全没概念。
| m****d 发帖数: 156 | 3 是的。能做些解释吗
【在 b*******e 的大作中提到】 : is it E?
| b*******e 发帖数: 67 | 4 my guess is that drugs are metabolized by enzymatic reactions, and enzymes
usually are isomer-specific, that is to say, they only operate on certain 构
象. thus substituting a D- to L- would lower affinity of the enzyme for the
substrate.
【在 m****d 的大作中提到】 : 是的。能做些解释吗
| m****d 发帖数: 156 | 5 thanks
the
【在 b*******e 的大作中提到】 : my guess is that drugs are metabolized by enzymatic reactions, and enzymes : usually are isomer-specific, that is to say, they only operate on certain 构 : 象. thus substituting a D- to L- would lower affinity of the enzyme for the : substrate.
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