1. 15y girl had recurrent candidal infections of the skin and nucous
membranes since childhood, 2 years Hx of type 1 DM and 1y Hx of autoimmune
thyroiditis.
Which of the following is the most likelymechanism of her recurrent candidal
infections?
A. Autoimmune destruction of the thymus
B. Blunting of the inflammatory response from complement deficiency
C. deficiency in anticandidal Ab
D. Impaired cell-mediated immunity
E. inability of macrophage to present candidal antigen
I thought this girl has Polyglandular autoimmune syndrome type I ( I saw
this disease before). But she did not have hypoparathyroidism or autoimmune
adrenal insufficiency.
Who can help explain it?
Thanks
h**s 发帖数: 1757
2
Don't over analysis .:>D
Only simple idea:
Fungal/bacteria infection relates with cell immunity; virus relates B-
cell
immunity.(Humoral immunity ) :>))
