A**********9
发帖数: 151 | 1 请版上的朋友帮忙看看，我们小组讨论后，对这两题还有疑问。谢谢！
1. A 3-week-old newborn is brought to the physician because of recurrent
vomiting after feeding since birth. The mother says that her child is eager
to feed even after vomiting. There is no fever. Abdominal examination shows
a firm, 1-to 2-cm, mobile mass in the epigastrium to the right of the
midline. If this condition has a lower threshold of liability in males than
in females, which of the following relative of this patient is at greatest
risk of also developing this disorder?
A. Brother, if newborn is female.
B. Brother, if newborn is male
C. Fraternal male twin, if newborn is male.
D. Sister, if newborn is female.
E. Sister, if newborn is male.
答案是A，但是我们觉得B也对啊，幽门狭窄征不是好发于boy吗？
2. A-34-year-old woman gives birth to a newborn at 32 weeks’ gestation
with a small placenta. The newborn is found to have multiple anomalies,
including bilateral simian creases and a small thorax. The newborn dies 2
hours after birth. Chromosomal analysis shows a karyotype of 69, XXY. DNA
analysis indicates that two sets of chromosomes are maternal in origin and
one is paternal. Studies from other triploid pregnancies have shown that
triploidy due to two sets of paternal chromosomes has poorly developed
embryonic tissue. Differing phenotypes dependent on parental origin are most
compatible with which of the following genetic mechanisms?
A. Anticipation
B. Expansion of trinucleotide repeats.
C. Imprinting
D. Loss of heterozygosity.
E. Pleiotropy.
答案是C， 没有疑问。但是我们想知道题里面提到的是什么病？FA里69,XXY只有在
partial mole提到。 | h**********a
发帖数: 74 | 2 这道题，你想得太复杂了，它是问最大风险的，当然是A这种情况最有可能。本身男性
发病率高于女性，如果女性发病了，它的男性亲属发病的可能性当然更大了。
recurrent
eager
shows
than
【在 A**********9 的大作中提到】
: 请版上的朋友帮忙看看，我们小组讨论后，对这两题还有疑问。谢谢！
: 1. A 3-week-old newborn is brought to the physician because of recurrent
: vomiting after feeding since birth. The mother says that her child is eager
: to feed even after vomiting. There is no fever. Abdominal examination shows
: a firm, 1-to 2-cm, mobile mass in the epigastrium to the right of the
: midline. If this condition has a lower threshold of liability in males than
: in females, which of the following relative of this patient is at greatest
: risk of also developing this disorder?
: A. Brother, if newborn is female.
: B. Brother, if newborn is male
| c**********c
发帖数: 1378 | | A**********9
发帖数: 151 | |
|
