h****g
发帖数: 45 | 1 发小儿想了解一下在美国有没有什么好方法可以治疗血小板无力 Glanzmann
thrombasthenia.我是外行,google出来的都是research articles. 所以想在这里问一
下大家,可不可以指点一下到哪里可以找到临床方面的信息,或者如果有人碰巧知道更详
细点的比如医生,医院,研究所什么的那就太感谢了.祝大家中秋阖家欢乐. | f****o
发帖数: 2770 | 2 Patients with Glanzmann thrombasthenia who are bleeding require platelet
transfusion.
Because patients are likely to require multiple transfusions during their
lifetime, take care to avoid platelet alloimmunization.
Prevention is best accomplished by using leukocyte-depleted blood products.
Leukocyte depletion can be accomplished with mechanical filtration. Only
filtered blood products should be given.
Use of platelets matched via human leukocyte antigen (HLA) is a further
attempt to prevent platelet alloimmunization.
Patients should be vaccinated for hepatitis B due to the infectious risks
associated with multiple transfusions
Avoid medications that affect platelet function, such as aspirin and other
nonsteroidal anti-inflammatory drugs (NSAIDs).
Consider oral contraceptives to control menorrhagia.
Recombinant human-activated factor VII (rFVII) has been used in patients
with antibodies to GP IIb/IIIa and/or HLA that render transfusions
ineffective. The exact dosing of rFVII for Glanzmann thrombasthenia has not
been determined. | f****o
发帖数: 2770 | 3 Patients with Glanzmann thrombasthenia who are bleeding require platelet
transfusion.
Because patients are likely to require multiple transfusions during their
lifetime, take care to avoid platelet alloimmunization.
Prevention is best accomplished by using leukocyte-depleted blood products.
Leukocyte depletion can be accomplished with mechanical filtration. Only
filtered blood products should be given.
Use of platelets matched via human leukocyte antigen (HLA) is a further
attempt to prevent platelet alloimmunization.
Patients should be vaccinated for hepatitis B due to the infectious risks
associated with multiple transfusions
Avoid medications that affect platelet function, such as aspirin and other
nonsteroidal anti-inflammatory drugs (NSAIDs).
Consider oral contraceptives to control menorrhagia.
Recombinant human-activated factor VII (rFVII) has been used in patients
with antibodies to GP IIb/IIIa and/or HLA that render transfusions
ineffective. The exact dosing of rFVII for Glanzmann thrombasthenia has not
been determined. | h****g
发帖数: 45 | 4 谢谢,我也是在网上google了一下,和你说的差不多,目前看来没有什么很有效果的治疗
方案或药物.
.
【在 f****o 的大作中提到】
: Patients with Glanzmann thrombasthenia who are bleeding require platelet
: transfusion.
: Because patients are likely to require multiple transfusions during their
: lifetime, take care to avoid platelet alloimmunization.
: Prevention is best accomplished by using leukocyte-depleted blood products.
: Leukocyte depletion can be accomplished with mechanical filtration. Only
: filtered blood products should be given.
: Use of platelets matched via human leukocyte antigen (HLA) is a further
: attempt to prevent platelet alloimmunization.
: Patients should be vaccinated for hepatitis B due to the infectious risks
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