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发帖数: 1810 | 1 是不是还残留癌细胞，没有PCR？
Final Diagnosis
A. BREAST, LEFT, 10 O'CLOCK (LUMPECTOMY):
- RESIDUAL INVASIVE DUCTAL CARCINOMA, NOTTINGHAM GRADE 2 OF 3, MULTIFOCALLY
INVOLVING A 1.5 CM TUMOR BED (LARGEST CONTIGUOUS FOCUS OF INVASIVE CARCINOMA
IS 1.3 CM), WITH TREATMENT RESPONSE/EFFECT. MARGINS NEGATIVE FOR INVASIVE
CARCINOMA - INVASIVE CARCINOMA EXTENDS TO 1.5 MM FROM THE INFERIOR MARGIN (
SEE PART E FOR FINAL INFERIOR MARGIN). SEE COMMENT AND SYNOPTIC REPORT.
- DUCTAL CARCINOMA IN SITU (DCIS), HIGH AND LOW NUCLEAR GRADE, SOLID AND
CRIBRIFORM PATTERNS WITH CENTRAL NECROSIS AND INVOLVEMENT OF SCLEROSING
ADENOSIS. DCIS IS PRESENT 0.5 MM FROM THE SUPERIOR MARGIN, 1.5 MM FROM THE
MEDIAL MARGIN, AND 1 MM FROM THE INFERIOR MARGIN (SEE PART E FOR FINAL
INFERIOR MARGIN). SEE COMMENT.
- SCLEROSING ADENOSIS, COLUMNAR CELL CHANGE, USUAL DUCTAL HYPERPLASIA,
FIBROADENOMATOUS CHANGE, DUCT ECTASIA, CALCIFICATIONS, AND BIOPSY SITE
CHANGES
- BENIGN SKIN
Comment
DCIS is seen in multiple blocks (10 out of 20 blocks of breast tissue
evaluated) in association with and away from the biopsy site. It is present
as high-grade DCIS with central necrosis and also as separate, distinct foci
of low-grade DCIS involving sclerosing adenosis.
The invasive carcinoma shows some features suggestive of partial squamous
differentiation.
Immunostains for p63, smooth muscle myosin heavy chain, and e-cadherin are
evaluated and support the diagnosis. |
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