w*p
发帖数: 16484 | 1 【 以下文字转载自 Biology 讨论区 】
发信人: wuyanzhe (唔言), 信区: Biology
标 题: 终于出来第一步Nature Biotech: editorial expression of concern
发信站: BBS 未名空间站 (Mon Nov 28 18:08:10 2016, 美东)
http://www.nature.com/nbt/journal/v34/n7/full/nbt.3547.html#correction1 | w*p
发帖数: 16484 | 2 Corrected online 28 November 2016
The editors of Nature Biotechnology are issuing an editorial expression
of concern regarding this article to alert our readers to concerns regarding
the reproducibility of the original results. At this time, we are
publishing the results of three groups http://dx.doi.org/10.1038/nbt.3753 that have tried to reproduce the results in the critical Figure 4 in the original paper by Han and colleagues, which demonstrates editing of endogenous genomic loci in mammalian cells. None of the groups observed any induction of mutations by NgAgo at any of the loci or under any of the conditions tested above the sensitivity of the assays used. Similar results have been recently reported by a different group of authors in Protein & Cell (doi:10.1007/s13238-016-0343-9).
We are in contact with the authors, who are investigating potential
causes for the lack of reproducibility. The authors have been informed of
this statement. While the investigations are ongoing, Chunyu Han and Xiao Z.
Shen agree with this editorial expression of concern. Feng Gao, Feng Jiang
and Yongqiang Wu do not feel that it is appropriate at this time.
We will update our readers once these investigations are complete. | w*p
发帖数: 16484 | | m*****u
发帖数: 15526 | | T******y
发帖数: 14506 | | k**********4
发帖数: 16092 | 6 very sad, sigh...
【在 w*p 的大作中提到】
: 看看这次韩春雨又怎么表现他高超的语言技巧
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