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发帖数: 4 | 1 We are seeking a highly motivated Scientist II/III with strong interpersonal
communication skills to join the growing and innovative Cancer Immunology &
Immune Modulation (CI & IM) Research Group at Boehringer Ingelheim’s US
research facility in Ridgefield, CT. The successful candidate will work
within the CI&IM in vivo pharmacology group to advance both exploratory and
drug candidate discovery programs and provide target discovery/validation,
in-vivo efficacy, mechanism of action (MOA) and pharmacodynamic data
essential to drive projects into clinical development. The ideal candidate
will collaborate with other members of in-vivo teams and with key
responsibilities involving primarily designing and conducting in vivo
pharmacology models of inflammation and oncology, as well as establishing
early PK/PD for lead progression.
As an employee of Boehringer Ingelheim, you will actively contribute to the
discovery, development and delivery of our products to our patients and
customers. Our global presence provides opportunity for all employees to
collaborate internationally, offering visibility and opportunity to directly
contribute to the companies' success. We realize that our strength and
competitive advantage lie with our people. We support our employees in a
number of ways to foster a healthy working environment, meaningful work,
diversity and inclusion, mobility, networking and work-life balance. Our
competitive compensation and benefit programs reflect Boehringer Ingelheim's
high regard for our employees.
Responsibilities:
•Execute research projects according to the experimental design,
ensure technically capable and provide accurate, reliable and reproducible
data.
•Independently perform in vivo studies, proficient in data collection/
documentation, interpret data and with mentorship, present to project teams.
•Collaborate extensively with other members of the Immune Modulation
Group in Ridgefield, while synergizing effectively with the in vivo
pharmacology group in the Inflammation & Respiratory therapeutic area.
•Expand scientific/technical knowledge and skill sets by regularly
reading relevant scientific literature and implement learnings in the study
designs or project strategies.
•Ensure that the highest standard of animal welfare is maintained in
all studies involving experimental animals.
•Understand and implement study protocol according to AAALAC and IACUC
guidelines.
Scientist II Requirements:
•Bachelor’s Degree from an accredited institution with three-plus (3+
) years of experience in related scientific discipline or Master’s Degree
from an accredited institution in related scientific discipline or
equivalent experience in related field
•Extensive hands-on experience on conducting rodent experiments
including preparation of test compounds, handling and dosing mice by various
routes (IP, SC, IV or PO), collection of blood and tissues for PK and PD
biomarker analysis.
•Familiar with human or murine primary cell isolation, cytokine
profiling by ELISA or MSD, T cell and/or myeloid cell functional assays,
Western blot, and qPCR. Experience in using multi-color flow cytometry (
FACS) to evaluate immune cell biomarkers and data analysis software is a
plus.
•Past experience with syngeneic or xenograft tumor models or PDX
models is preferred. Familiarity with hydrodynamic tail vein injection is a
plus but not required.
•Excellent oral and written communication skills. Proficiency in all
common Microsoft Office and Graphpad Prism software.
•Strong ability to multi-task and willingness to work effectively in a
fast-paced, highly collaborative, and diverse research environment.
•The ability to work independent and be a team player.
Scientist III Requirements:
•Master’s Degree from an accredited institution with three-plus (3+)
years of experience in related scientific discipline, OR Bachelor’s Degree
from an accredited institution with seven-plus (7+) years of experience in
related scientific discipline or equivalent experience in related field
•Extensive hands-on experience on conducting rodent experiments
including preparation of test compounds, handling and dosing mice by various
routes (IP, SC, IV or PO), collection of blood and tissues for PK and PD
biomarker analysis.
•Familiar with human or murine primary cell isolation, cytokine
profiling by ELISA or MSD, T cell and/or myeloid cell functional assays,
Western blot, and qPCR. Experience in using multi-color flow cytometry (
FACS) to evaluate immune cell biomarkers and data analysis software is a
plus.
•Past experience with syngeneic or xenograft tumor models or PDX
models is preferred. Familiarity with hydrodynamic tail vein injection is a
plus but not required.
•Excellent oral and written communication skills. Proficiency in all
common Microsoft Office and Graphpad Prism software.
•Strong ability to multi-task and willingness to work effectively in a
fast-paced, highly collaborative, and diverse research environment.
•The ability to work independent and be a team player.
Eligibility Requirements:
•Must be legally authorized to work in the United States without
restriction.
•Must be willing to take a drug test and post-offer physical (if
required)
•Must be 18 years of age or older
Who We Are:
At Boehringer Ingelheim we create value through innovation with one clear
goal: to improve the lives of patients. We develop breakthrough therapies
and innovative healthcare solutions in areas of unmet medical need for both
humans and animals. As a family owned company we focus on long term
performance. We are powered by 50.000 employees globally who nurture a
diverse, collaborative and inclusive culture. Learning and development for
all employees is key because your growth is our growth. Want to learn more?
Visit boehringer-ingelheim.com and join us in our effort to make more
health. Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals
, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal Health USA,
Inc., Merial Barceloneta, LLC and Boehringer Ingelheim Fremont, Inc. is an
equal opportunity and affirmative action employer committed to a culturally
diverse workforce. All qualified applicants will receive consideration for
employment without regard to race; color; creed; religion; national origin;
age; ancestry; nationality; marital, domestic partnership or civil union
status; sex, gender identity or expression; affectional or sexual
orientation; disability; veteran or military status, including protected
veteran status; domestic violence victim status; atypical cellular or blood
trait; genetic information (including the refusal to submit to genetic
testing) or any other characteristic protected by law.
If interested, please apply through the link:
https://tas-boehringer.taleo.net/careersection/global+template+career+
section+28external29/jobdetail.ftl?job=192183&tz=GMT-08%3A00 |
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