s*r 发帖数: 2757 | 1 http://robertfortner.posterous.com/if-heart-drugs-keep-improving-will-we-be-able
But as research dives deeper, the medical payoff has become fainter. The
tether connecting research to new drugs and health benefits began stretching
a quarter century ago. In 1984, a group at Oxford quietly and presciently
called for megatrials in the 10,000- to 20,000-person range because most
trials were “too small to be of much independent value.” In other words,
drug benefits had become too small to be detecte |
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