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Pharmaceutical版 - question about blood/plasma stability
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话题: plasma话题: blood话题: stability话题: question话题: about
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1 (共1页)
p*******y
发帖数: 133
1
We routinely do blood/plasma stability to decide what kind of samples to
take for PK studies.
Can somebody explain why some compounds are more stable in blood than in
plasma?
I can not understand why.
c********g
发帖数: 1106
2
speculation: those are highly sequestered in blood cells.

【在 p*******y 的大作中提到】
: We routinely do blood/plasma stability to decide what kind of samples to
: take for PK studies.
: Can somebody explain why some compounds are more stable in blood than in
: plasma?
: I can not understand why.

E***n
发帖数: 308
3
I guess, it may involve hydrolytic rxn, enzyme rxn et al

【在 p*******y 的大作中提到】
: We routinely do blood/plasma stability to decide what kind of samples to
: take for PK studies.
: Can somebody explain why some compounds are more stable in blood than in
: plasma?
: I can not understand why.

1 (共1页)
进入Pharmaceutical版参与讨论
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话题: plasma话题: blood话题: stability话题: question话题: about