O***n 发帖数: 13127 | 1 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin binding is essential for coronin 1B
function in vivo. J Cell Sci. 2007 May 15;120(Pt 10):1779-90. Epub 2007 Apr
24.
PubMed PMID: 17456547.
Cai L, Marshall TW, Uetrecht AC, Schafer DA, Bear JE. Coronin 1B coordinates
Arp2/3 complex and cofilin activities at the leading edge. Cell. 2007 Mar
9;128(5):915-29. PubMed PMID: 17350576; PubMed Central PMCID: PMC2630706.
Marshall TW, Cai L, Bear JE. Chemistry comes to the cell: ASCB 2005. Nat
Chem
Biol. 2006 Mar;2(3):119-22. PubMed PMID: 16484998.
Cai L, Holoweckyj N, Schaller MD, Bear JE. Phosphorylation of coronin 1B by
protein kinase C regulates interaction with Arp2/3 and cell motility. J Biol
Chem. 2005 Sep 9;280(36):31913-23. Epub 2005 Jul 18. PubMed PMID: 16027158.
126 欧光朔 男 1976年10月 中国科学院生物物理研究所 生命
科学 2006年06月毕业于[美国]加州大学戴维斯分校 [美国]加州大学旧金山分校
1: Ou G, Stuurman N, D'Ambrosio M, Vale RD. Polarized myosin produces
unequal-size daughters during asymmetric cell division. Science. 2010 Oct
29;330(6004):677-80. Epub 2010 Sep 30. PubMed PMID: 20929735; PubMed Central
PMCID: PMC3032534.
2: Ou G, Vale RD. Molecular signatures of cell migration in C. elegans Q
neuroblasts. J Cell Biol. 2009 Apr 6;185(1):77-85. PubMed PMID: 19349580;
PubMed
Central PMCID: PMC2700521.
3: Hao L, Acar S, Evans J, Ou G, Scholey JM. Analysis of intraflagellar
transport
in C. elegans sensory cilia. Methods Cell Biol. 2009;93:235-66. Epub 2009
Dec 4.
PubMed PMID: 20409821.
4: Ou G, Koga M, Blacque OE, Murayama T, Ohshima Y, Schafer JC, Li C, Yoder
BK,
Leroux MR, Scholey JM. Sensory ciliogenesis in Caenorhabditis elegans:
assignment
of IFT components into distinct modules based on transport and phenotypic
profiles. Mol Biol Cell. 2007 May;18(5):1554-69. Epub 2007 Feb 21. PubMed
PMID:
17314406; PubMed Central PMCID: PMC1855012.
5: Pan X, Ou G, Civelekoglu-Scholey G, Blacque OE, Endres NF, Tao L,
Mogilner A,
Leroux MR, Vale RD, Scholey JM. Mechanism of transport of IFT particles in C.
elegans cilia by the concerted action of kinesin-II and OSM-3 motors. J Cell
Biol. 2006 Sep 25;174(7):1035-45. PubMed PMID: 17000880; PubMed Central
PMCID:
PMC2064394.
6: Evans JE, Snow JJ, Gunnarson AL, Ou G, Stahlberg H, McDonald KL, Scholey
JM.
Functional modulation of IFT kinesins extends the sensory repertoire of
ciliated
neurons in Caenorhabditis elegans. J Cell Biol. 2006 Feb 27;172(5):663-9.
Epub
2006 Feb 21. Erratum in: J Cell Biol. 2006 Mar 13;172(6):949. J Cell Biol.
2006
Dec 4;175(5):837. PubMed PMID: 16492809; PubMed Central PMCID: PMC2063699.
7: Ou G, Blacque OE, Snow JJ, Leroux MR, Scholey JM. Functional coordination
of
intraflagellar transport motors. Nature. 2005 Jul 28;436(7050):583-7. PubMed
PMID: 16049494.
8: Ou G, Qin H, Rosenbaum JL, Scholey JM. The PKD protein qilin undergoes
intraflagellar transport. Curr Biol. 2005 Jun 7;15(11):R410-1. PubMed PMID:
15936258.
127 柳振峰 男 1977年11月 中国科学院生物物理研究所 生命
科学 2004年08月毕业于[中国]中科院生物物理所 [美国]加州理工学院/休斯医
学研究所 博士后/助理研究员
5: Liu Z, Walton TA, Rees DC. A reported archaeal mechanosensitive channel
is a
structural homolog of MarR-like transcriptional regulators. Protein Sci.
2010
Apr;19(4):808-14. PubMed PMID: 20162616; PubMed Central PMCID: PMC2867020.
6: Liu Z, Gandhi CS, Rees DC. Structure of a tetrameric MscL in an expanded
intermediate state. Nature. 2009 Sep 3;461(7260):120-4. Epub 2009 Aug 23.
PubMed
PMID: 19701184; PubMed Central PMCID: PMC2737600.
7: Yan H, Zhang P, Wang C, Liu Z, Chang W. Two lutein molecules in LHCII
have
different conformations and functions: Insights into the molecular mechanism
of
thermal dissipation in plants. Biochem Biophys Res Commun. 2007 Apr
6;355(2):457-63. Epub 2007 Feb 7. PubMed PMID: 17303080.
8: Pascal AA, Liu Z, Broess K, van Oort B, van Amerongen H, Wang C, Horton P,
Robert B, Chang W, Ruban A. Molecular basis of photoprotection and control
of
photosynthetic light-harvesting. Nature. 2005 Jul 7;436(7047):134-7. PubMed
PMID:
16001075.
9: Liu Z, Yan H, Wang K, Kuang T, Zhang J, Gui L, An X, Chang W. Crystal
structure of spinach major light-harvesting complex at 2.72 A resolution.
Nature.
2004 Mar 18;428(6980):287-92. PubMed PMID: 15029188.
128 刘晓 男 1973年2月 清华大学 生命
科学 2005年05月毕业于[美国]约翰霍普金斯医学院 [美国]斯坦福大学医学院
博士后
1: Liu X, Long F, Peng H, Aerni SJ, Jiang M, Sánchez-Blanco A, Murray JI,
Preston
E, Mericle B, Batzoglou S, Myers EW, Kim SK. Analysis of cell fate from
single-cell gene expression profiles in C. elegans. Cell. 2009 Oct
30;139(3):623-33. PubMed PMID: 19879847.
2: Liu X, Lee CK, Granek JA, Clarke ND, Lieb JD. Whole-genome comparison of
Leu3
binding in vitro and in vivo reveals the importance of nucleosome occupancy
in
target site selection. Genome Res. 2006 Dec;16(12):1517-28. Epub 2006 Oct 19.
PubMed PMID: 17053089; PubMed Central PMCID: PMC1665635.
3: Tang L, Liu X, Clarke ND. Inferring direct regulatory targets from
expression
and genome location analyses: a comparison of transcription factor deletion
and
overexpression. BMC Genomics. 2006 Aug 22;7:215. PubMed PMID: 16923194;
PubMed
Central PMCID: PMC1559704.
4: Liu X, Noll DM, Lieb JD, Clarke ND. DIP-chip: rapid and accurate
determination
of DNA-binding specificity. Genome Res. 2005 Mar;15(3):421-7. Epub 2005 Feb
14.
PubMed PMID: 15710749; PubMed Central PMCID: PMC551568.
5: Han Y, Lassen K, Monie D, Sedaghat AR, Shimoji S, Liu X, Pierson TC,
Margolick
JB, Siliciano RF, Siliciano JD. Resting CD4+ T cells from human
immunodeficiency
virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes
within
actively transcribed host genes. J Virol. 2004 Jun;78(12):6122-33. PubMed
PMID:
15163705; PubMed Central PMCID: PMC416493.
6: Villanueva MP, Aiyer AR, Muller S, Pletcher MT, Liu X, Emanuel B,
Srivastava
D, Reeves RH. Genetic and comparative mapping of genes dysregulated in mouse
hearts lacking the Hand2 transcription factor gene. Genomics. 2002
Dec;80(6):593-600. PubMed PMID: 12504851.
7: Liu X, Clarke ND. Rationalization of gene regulation by a eukaryotic
transcription factor: calculation of regulatory region occupancy from
predicted
binding affinities. J Mol Biol. 2002 Oct 11;323(1):1-8. PubMed PMID:
12368093.
129 周大旺 男 1976年1月 厦门大学 生命
科学 2006年07月毕业于[美国]爱因斯坦医学院 [美国]哈佛大学医学院 讲师
1: Schlegelmilch K, Mohseni M, Kirak O, Pruszak J, Rodriguez JR, Zhou D,
Kreger
BT, Vasioukhin V, Avruch J, Brummelkamp TR, Camargo FD. Yap1 acts downstream
of
α-catenin to control epidermal proliferation. Cell. 2011 Mar 4;144(5):782-
95.
PubMed PMID: 21376238.
2: Barbagallo AP, Weldon R, Tamayev R, Zhou D, Giliberto L, Foreman O, D'
Adamio
L. Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP
processing in vivo. PLoS One. 2010 Nov 16;5(11):e15503. PubMed PMID:
21103325;
PubMed Central PMCID: PMC2982846.
3: Zhou D, Conrad C, Xia F, Park JS, Payer B, Yin Y, Lauwers GY, Thasler W,
Lee
JT, Avruch J, Bardeesy N. Mst1 and Mst2 maintain hepatocyte quiescence and
suppress hepatocellular carcinoma development through inactivation of the
Yap1
oncogene. Cancer Cell. 2009 Nov 6;16(5):425-38. PubMed PMID: 19878874;
PubMed
Central PMCID: PMC3023165.
4: Tamayev R, Zhou D, D'Adamio L. The interactome of the amyloid beta
precursor
protein family members is shaped by phosphorylation of their intracellular
domains. Mol Neurodegener. 2009 Jul 14;4:28. PubMed PMID: 19602287; PubMed
Central PMCID: PMC2723102.
5: Zhou D, Zambrano N, Russo T, D'Adamio L. Phosphorylation of a tyrosine in
the
amyloid-beta protein precursor intracellular domain inhibits Fe65 binding
and
signaling. J Alzheimers Dis. 2009;16(2):301-7. PubMed PMID: 19221419.
6: Avruch J, Xavier R, Bardeesy N, Zhang XF, Praskova M, Zhou D, Xia F.
Rassf
family of tumor suppressor polypeptides. J Biol Chem. 2009 Apr
24;284(17):11001-5. Epub 2008 Dec 17. Review. PubMed PMID: 19091744; PubMed
Central PMCID: PMC2670104.
7: Zhou D, Medoff BD, Chen L, Li L, Zhang XF, Praskova M, Liu M, Landry A,
Blumberg RS, Boussiotis VA, Xavier R, Avruch J. The Nore1B/Mst1 complex
restrains
antigen receptor-induced proliferation of naïve T cells. Proc Natl Acad
Sci U S
A. 2008 Dec 23;105(51):20321-6. Epub 2008 Dec 10. PubMed PMID: 19073936;
PubMed
Central PMCID: PMC2600581.
8: Giliberto L, Zhou D, Weldon R, Tamagno E, De Luca P, Tabaton M, D'Adamio
L.
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers
the
stress threshold of neurons and has a "regulated" transcriptional role. Mol
Neurodegener. 2008 Sep 2;3:12. PubMed PMID: 18764939; PubMed Central PMCID:
PMC2538519.
9: D'Ambrosio C, Arena S, Fulcoli G, Scheinfeld MH, Zhou D, D'Adamio L,
Scaloni
A. Hyperphosphorylation of JNK-interacting protein 1, a protein associated
with
Alzheimer disease. Mol Cell Proteomics. 2006 Jan;5(1):97-113. Epub 2005 Sep
29.
PubMed PMID: 16195223.
10: Zhou D, Noviello C, D'Ambrosio C, Scaloni A, D'Adamio L. Growth factor
receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail
of
amyloid beta precursor protein is mediated by its Src homology 2 domain. J
Biol
Chem. 2004 Jun 11;279(24):25374-80. Epub 2004 Mar 30. PubMed PMID: 15054097.
130 蔡毓 男 1971年11月 厦门大学 生命
科学 2003年06月毕业于[新加坡]新加坡分子和细胞生物学研究所/新加坡国立大学
[新加坡]淡马锡生命科学研究院 助理教授
1: Liu M, Lim TM, Cai Y. The Drosophila female germline stem cell lineage
acts to
spatially restrict DPP function within the niche. Sci Signal. 2010 Jul
27;3(132):ra57. PubMed PMID: 20664066.
2: Tao S, Cai Y, Sampath K. The Integrator subunits function in
hematopoiesis by
modulating Smad/BMP signaling. Development. 2009 Aug;136(16):2757-65. Epub
2009
Jul 15. PubMed PMID: 19605500.
3: Wang L, Li Z, Cai Y. The JAK/STAT pathway positively regulates DPP
signaling
in the Drosophila germline stem cell niche. J Cell Biol. 2008 Feb
25;180(4):721-8. Epub 2008 Feb 18. PubMed PMID: 18283115; PubMed Central
PMCID:
PMC2265565.
4: Li Z, Wang L, Hays TS, Cai Y. Dynein-mediated apical localization of
crumbs
transcripts is required for Crumbs activity in epithelial polarity. J Cell
Biol.
2008 Jan 14;180(1):31-8. PubMed PMID: 18195099; PubMed Central PMCID:
PMC2213619.
5: Wang H, Cai Y, Chia W, Yang X. Drosophila homologs of mammalian
TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in
neuroblasts. EMBO J. 2006 Dec 13;25(24):5783-93. Epub 2006 Nov 30. PubMed
PMID:
17139248; PubMed Central PMCID: PMC1698905.
6: Cai Y, Lim Z, Lim BA, Oen F, Yan XM, Li MY, Seah S. [The long-term effect
of
phacoemulsification combined with trabeculectomy and intraoperative
5-fluorouracil in glaucoma patients]. Zhonghua Yan Ke Za Zhi. 2005
Feb;41(2):128-31. Chinese. PubMed PMID: 15840338.
7: Cai Y, Yu F, Lin S, Chia W, Yang X. Apical complex genes control mitotic
spindle geometry and relative size of daughter cells in Drosophila
neuroblast and
pI asymmetric divisions. Cell. 2003 Jan 10;112(1):51-62. PubMed PMID:
12526793.
131 光寿红 男 1974年4月 中国科学技术大学 生命
科学 2004年12月毕业于[美国]威斯康星大学 [美国]威斯康星大学 研究员
1: Guang S, Bochner AF, Burkhart KB, Burton N, Pavelec DM, Kennedy S. Small
regulatory RNAs inhibit RNA polymerase II during the elongation phase of
transcription. Nature. 2010 Jun 24;465(7301):1097-101. Epub 2010 Jun 13.
PubMed
PMID: 20543824; PubMed Central PMCID: PMC2892551.
2: Guang S, Bochner AF, Pavelec DM, Burkhart KB, Harding S, Lachowiec J,
Kennedy
S. An Argonaute transports siRNAs from the cytoplasm to the nucleus. Science.
2008 Jul 25;321(5888):537-41. Erratum in: Science. 2009 Dec 4;326(5958):1346.
PubMed PMID: 18653886; PubMed Central PMCID: PMC2771369.
3: Guang S, Felthauser AM, Mertz JE. Binding of hnRNP L to the pre-mRNA
processing enhancer of the herpes simplex virus thymidine kinase gene
enhances
both polyadenylation and nucleocytoplasmic export of intronless mRNAs. Mol
Cell
Biol. 2005 Aug;25(15):6303-13. PubMed PMID: 16024770; PubMed Central PMCID:
PMC1190326.
4: Guang S, Mertz JE. Pre-mRNA processing enhancer (PPE) elements from
intronless
genes play additional roles in mRNA biogenesis than do ones from
intron-containing genes. Nucleic Acids Res. 2005 Apr 20;33(7):2215-26. Print
2005. PubMed PMID: 15843684; PubMed Central PMCID: PMC1083424.
132 汪阳明 男 1979年12月 北京大学 生命
科学 2006年02月毕业于[美国]伊利诺伊大学厄巴纳-尚佩恩分校 [美国]加州大
学旧金山分校 博士后
1: Wang Y, Blelloch R. Cell cycle regulation by microRNAs in stem cells.
Results
Probl Cell Differ. 2011;53:459-72. PubMed PMID: 21630156.
2: Wang Y, Blelloch R. Cell cycle regulation by MicroRNAs in embryonic stem
cells. Cancer Res. 2009 May 15;69(10):4093-6. Epub 2009 May 12. Review.
PubMed
PMID: 19435891; PubMed Central PMCID: PMC2894693.
3: Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R.
Embryonic
stem cell-specific microRNAs regulate the G1-S transition and promote rapid
proliferation. Nat Genet. 2008 Dec;40(12):1478-83. Epub 2008 Nov 2. PubMed
PMID:
18978791; PubMed Central PMCID: PMC2630798.
4: Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. Mouse ES cells
express
endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-
dependent
small RNAs. Genes Dev. 2008 Oct 15;22(20):2773-85. PubMed PMID: 18923076;
PubMed
Central PMCID: PMC2569885.
5: Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. DGCR8 is essential
for
microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat
Genet.
2007 Mar;39(3):380-5. Epub 2007 Jan 28. PubMed PMID: 17259983; PubMed
Central
PMCID: PMC3008549.
6: Wang Y, Silverman SK. Experimental tests of two proofreading mechanisms
for
5'-splice site selection. ACS Chem Biol. 2006 Jun 20;1(5):316-24. PubMed
PMID:
17163761.
7: Wang Y, Silverman SK. Efficient RNA 5'-adenylation by T4 DNA ligase to
facilitate practical applications. RNA. 2006 Jun;12(6):1142-6. Epub 2006 Apr
17.
PubMed PMID: 16618967; PubMed Central PMCID: PMC1464850.
8: Zelin E, Wang Y, Silverman SK. Adenosine is inherently favored as the
branch-site RNA nucleotide in a structural context that resembles natural
RNA
splicing. Biochemistry. 2006 Mar 7;45(9):2767-71. PubMed PMID: 16503631;
PubMed
Central PMCID: PMC2515823.
9: Wang Y, Silverman SK. A general two-step strategy to synthesize lariat
RNAs.
RNA. 2006 Feb;12(2):313-21. Epub 2005 Dec 22. PubMed PMID: 16373486; PubMed
Central PMCID: PMC1370911.
10: Wang Y, Silverman SK. Efficient one-step synthesis of biologically
related
lariat RNAs by a deoxyribozyme. Angew Chem Int Ed Engl. 2005 Sep
12;44(36):5863-6. PubMed PMID: 16086354; PubMed Central PMCID: PMC1513635.
11: Pratico ED, Wang Y, Silverman SK. A deoxyribozyme that synthesizes
2',5'-branched RNA with any branch-site nucleotide. Nucleic Acids Res. 2005
Jun
20;33(11):3503-12. Print 2005. PubMed PMID: 15967808; PubMed Central PMCID:
PMC1153712.
12: Wang Y, Silverman SK. Directing the outcome of deoxyribozyme selections
to
favor native 3'-5' RNA ligation. Biochemistry. 2005 Mar 1;44(8):3017-23.
PubMed
PMID: 15723545.
13: Wang Y, Silverman SK. Characterization of deoxyribozymes that synthesize
branched RNA. Biochemistry. 2003 Dec 30;42(51):15252-63. PubMed PMID:
14690435.
14: Wang Y, Silverman SK. Deoxyribozymes that synthesize branched and lariat
RNA.
J Am Chem Soc. 2003 Jun 11;125(23):6880-1. PubMed PMID: 12783536.
15: Flynn-Charlebois A, Wang Y, Prior TK, Rashid I, Hoadley KA, Coppins RL,
Wolf
AC, Silverman SK. Deoxyribozymes with 2'-5' RNA ligase activity. J Am Chem
Soc.
2003 Mar 5;125(9):2444-54. PubMed PMID: 12603132.
133 张华凤 女 1973年1月 中国科学技术大学 生命
科学 2004年03月毕业于[日本]东京大学 [美国]约翰霍普金斯大学医学院 研
究助理
1: Yoshida T, Zhang H, Iwase T, Shen J, Semenza GL, Campochiaro PA. Digoxin
inhibits retinal ischemia-induced HIF-1alpha expression and ocular
neovascularization. FASEB J. 2010 Jun;24(6):1759-67. Epub 2010 Jan 11.
PubMed
PMID: 20065104; PubMed Central PMCID: PMC2874483.
2: Lee K, Zhang H, Qian DZ, Rey S, Liu JO, Semenza GL. Acriflavine inhibits
HIF-1
dimerization, tumor growth, and vascularization. Proc Natl Acad Sci U S A.
2009
Oct 20;106(42):17910-5. Epub 2009 Oct 1. PubMed PMID: 19805192; PubMed
Central
PMCID: PMC2764905.
3: Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, Rey S, Hammers H, Chang D,
Pili R, Dang CV, Liu JO, Semenza GL. Digoxin and other cardiac glycosides
inhibit
HIF-1alpha synthesis and block tumor growth. Proc Natl Acad Sci U S A. 2008
Dec
16;105(50):19579-86. Epub 2008 Nov 19. PubMed PMID: 19020076; PubMed Central
PMCID: PMC2604945.
4: Zhang H, Semenza GL. The expanding universe of hypoxia. J Mol Med (Berl).
2008
Jul;86(7):739-46. Epub 2008 Jun 13. PubMed PMID: 18551266; PubMed Central
PMCID:
PMC2720566.
5: Liu L, Marti GP, Wei X, Zhang X, Zhang H, Liu YV, Nastai M, Semenza GL,
Harmon
JW. Age-dependent impairment of HIF-1alpha expression in diabetic mice:
Correction with electroporation-facilitated gene therapy increases wound
healing,
angiogenesis, and circulating angiogenic cells. J Cell Physiol. 2008
Nov;217(2):319-27. PubMed PMID: 18506785; PubMed Central PMCID: PMC2716010.
6: Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez
FJ,
Semenza GL. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic
response to hypoxia. J Biol Chem. 2008 Apr 18;283(16):10892-903. Epub 2008
Feb
15. PubMed PMID: 18281291; PubMed Central PMCID: PMC2447655.
7: Bosch-Marce M, Okuyama H, Wesley JB, Sarkar K, Kimura H, Liu YV, Zhang H,
Strazza M, Rey S, Savino L, Zhou YF, McDonald KR, Na Y, Vandiver S, Rabi A,
Shaked Y, Kerbel R, Lavallee T, Semenza GL. Effects of aging and
hypoxia-inducible factor-1 activity on angiogenic cell mobilization and
recovery
of perfusion after limb ischemia. Circ Res. 2007 Dec 7;101(12):1310-8. Epub
2007
Oct 11. PubMed PMID: 17932327.
8: Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, Bhujwalla ZM, Felsher
DW,
Cheng L, Pevsner J, Lee LA, Semenza GL, Dang CV. HIF-dependent
antitumorigenic
effect of antioxidants in vivo. Cancer Cell. 2007 Sep;12(3):230-8. PubMed
PMID:
17785204; PubMed Central PMCID: PMC2084208.
9: Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI, Dang CV,
Semenza GL. HIF-1 inhibits mitochondrial biogenesis and cellular respiration
in
VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer
Cell.
2007 May;11(5):407-20. PubMed PMID: 17482131.
10: Fukuda R, Zhang H, Kim JW, Shimoda L, Dang CV, Semenza GL. HIF-1
regulates
cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic
cells. Cell. 2007 Apr 6;129(1):111-22. PubMed PMID: 17418790.
11: Liu YV, Baek JH, Zhang H, Diez R, Cole RN, Semenza GL. RACK1 competes
with
HSP90 for binding to HIF-1alpha and is required for O(2)-independent and
HSP90
inhibitor-induced degradation of HIF-1alpha. Mol Cell. 2007 Jan 26;25(2):207
-17.
PubMed PMID: 17244529; PubMed Central PMCID: PMC2563152.
134 麻锦彪 男 1973年5月 复旦大学 生命
科学 2002年07月毕业于[中国]中科院上海有机化学研究所 [美国]阿拉巴马大学
伯明翰分校 助理教授
1: Tian Y, Simanshu DK, Ma JB, Patel DJ. Structural basis for piRNA
2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille)
domains.
Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):903-10. Epub 2010 Dec 30.
PubMed
PMID: 21193640; PubMed Central PMCID: PMC3024652.
2: Huang Y, Ji L, Huang Q, Vassylyev DG, Chen X, Ma JB. Structural insights
into
mechanisms of the small RNA methyltransferase HEN1. Nature. 2009 Oct
8;461(7265):823-7. PubMed PMID: 19812675.
3: Yuan YR, Pei Y, Ma JB, Kuryavyi V, Zhadina M, Meister G, Chen HY, Dauter
Z,
Tuschl T, Patel DJ. Crystal structure of A. aeolicus argonaute, a site-
specific
DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA
cleavage.
Mol Cell. 2005 Aug 5;19(3):405-19. PubMed PMID: 16061186.
4: Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. Structural basis
for
5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Nature.
2005 Mar 31;434(7033):666-70. PubMed PMID: 15800629.
5: Phan AT, Kuryavyi V, Ma JB, Faure A, Andréola ML, Patel DJ. An
interlocked
dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1
integrase.
Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):634-9. Epub 2005 Jan 6. PubMed
PMID:
15637158; PubMed Central PMCID: PMC545538.
6: Ma JB, Ye K, Patel DJ. Structural basis for overhang-specific small
interfering RNA recognition by the PAZ domain. Nature. 2004 May
20;429(6989):318-22. PubMed PMID: 15152257.
135 孙育杰 男 1973年10月 北京大学 生命
科学 2005年03月毕业于[美国]匹兹堡大学 [美国]宾夕法尼亚大学 博士后
1: Sun Y, Goldman YE. Lever-arm mechanics of processive myosins. Biophys J.
2011
Jul 6;101(1):1-11. PubMed PMID: 21723809; PubMed Central PMCID: PMC3127180.
2: Park JH, Sun Y, Goldman YE, Composto RJ. Tunable nanoscale channels in
diblock
copolymer films for biomolecule organization. Langmuir. 2010 Jul
6;26(13):10961-7. PubMed PMID: 20459081; PubMed Central PMCID: PMC2894990.
3: Sun Y, Sato O, Ruhnow F, Arsenault ME, Ikebe M, Goldman YE. Single-
molecule
stepping and structural dynamics of myosin X. Nat Struct Mol Biol. 2010
Apr;17(4):485-91. Epub 2010 Apr 4. PubMed PMID: 20364131; PubMed Central
PMCID:
PMC2876314.
4: Arsenault ME, Sun Y, Bau HH, Goldman YE. Using electrical and optical
tweezers
to facilitate studies of molecular motors. Phys Chem Chem Phys. 2009 Jun
28;11(24):4834-9. Epub 2009 Apr 16. PubMed PMID: 19506758.
5: Sun Y, McKenna JD, Murray JM, Ostap EM, Goldman YE. Parallax: high
accuracy
three-dimensional single molecule tracking using split images. Nano Lett.
2009
Jul;9(7):2676-82. PubMed PMID: 19496608; PubMed Central PMCID: PMC2728077.
6: Sun Y, Schroeder HW 3rd, Beausang JF, Homma K, Ikebe M, Goldman YE.
Myosin VI
walks "wiggly" on actin with large and variable tilting. Mol Cell. 2007 Dec
28;28(6):954-64. PubMed PMID: 18158894; PubMed Central PMCID: PMC2683265.
7: Sun Y, Akhremitchev B, Walker GC. Using the adhesive interaction between
atomic force microscopy tips and polymer surfaces to measure the elastic
modulus
of compliant samples. Langmuir. 2004 Jul 6;20(14):5837-45. PubMed PMID:
16459598.
8: Sun Y, Walker GC. Viscoelastic response of poly(dimethylsiloxane) in the
adhesive interaction with AFM tips. Langmuir. 2005 Sep 13;21(19):8694-702.
PubMed
PMID: 16142950.
9: Lee SB, Koepsel RR, Morley SW, Matyjaszewski K, Sun Y, Russell AJ.
Permanent,
nonleaching antibacterial surfaces. 1. Synthesis by atom transfer radical
polymerization. Biomacromolecules. 2004 May-Jun;5(3):877-82. PubMed PMID:
15132676.
136 戴俊彪 男 1974年4月 清华大学 生命
科学 2006年08月毕业于[美国]衣荷华州立大学 [美国]约翰霍普金斯大学 博
士后
1: Hyland EM, Molina H, Poorey K, Jie C, Xie Z, Dai J, Qian J, Bekiranov S,
Auble
DT, Pandey A, Boeke JD. An evolutionarily 'young' lysine residue in histone
H3
attenuates transcriptional output in Saccharomyces cerevisiae. Genes Dev.
2011
Jun 15;25(12):1306-19. doi: 10.1101/gad.2050311. PubMed PMID: 21685365;
PubMed
Central PMCID: PMC3127431.
2: Dai J, Hyland EM, Norris A, Boeke JD. Yin and Yang of histone H2B roles
in
silencing and longevity: a tale of two arginines. Genetics. 2010
Nov;186(3):813-28. Epub 2010 Aug 16. PubMed PMID: 20713692; PubMed Central
PMCID:
PMC2975301.
3: Huang H, Maertens AM, Hyland EM, Dai J, Norris A, Boeke JD, Bader JS.
HistoneHits: a database for histone mutations and their phenotypes. Genome
Res.
2009 Apr;19(4):674-81. Epub 2009 Feb 13. PubMed PMID: 19218532; PubMed
Central
PMCID: PMC2666297.
4: Dai J, Hyland EM, Yuan DS, Huang H, Bader JS, Boeke JD. Probing
nucleosome
function: a highly versatile library of synthetic histone H3 and H4 mutants.
Cell. 2008 Sep 19;134(6):1066-78. PubMed PMID: 18805098; PubMed Central
PMCID:
PMC2701395.
5: Dai J, Xie W, Brady TL, Gao J, Voytas DF. Phosphorylation regulates
integration of the yeast Ty5 retrotransposon into heterochromatin. Mol Cell.
2007
Jul 20;27(2):289-99. PubMed PMID: 17643377.
6: Zhu Y, Dai J, Fuerst PG, Voytas DF. Controlling integration specificity
of a
yeast retrotransposon. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5891-5.
Epub
2003 May 1. PubMed PMID: 12730380; PubMed Central PMCID: PMC156297.
137 薛贵 男 1977年9月 北京师范大学 生命
科学 2004年06月毕业于[中国]北京师范大学 [美国]南加州大学 助理教授
1: Wong SW, Xue G, Bechara A. Integrating fMRI with psychophysiological
measurements in the study of decision-making. J Neurosci Psychol Econ.
2011;4(2):85-94. PubMed PMID: 21818407; PubMed Central PMCID: PMC3147053.
2: Li J, Chen C, Chen C, He Q, Li H, Li J, Moyzis RK, Xue G, Dong Q.
Neurotensin
receptor 1 gene (NTSR1) polymorphism is associated with working memory. PLoS
One.
2011 Mar 4;6(3):e17365. PubMed PMID: 21394204; PubMed Central PMCID:
PMC3048867.
3: Xue G, Lu Z, Levin IP, Bechara A. An fMRI study of risk-taking following
wins
and losses: implications for the gambler's fallacy. Hum Brain Mapp. 2011
Feb;32(2):271-81. doi: 10.1002/hbm.21015. PubMed PMID: 21229615.
4: Zhang M, Jiang T, Mei L, Yang H, Chen C, Xue G, Dong Q. It's a word:
early
electrophysiological response to the character likeness of pictographs.
Psychophysiology. 2011 Jul;48(7):950-9. doi: 10.1111/j.1469-8986.2010.01153.
x.
Epub 2010 Nov 23. PubMed PMID: 21091960.
5: Xue G, Mei L, Chen C, Lu ZL, Poldrack RA, Dong Q. Facilitating memory for
novel characters by reducing neural repetition suppression in the left
fusiform
cortex. PLoS One. 2010 Oct 6;5(10):e13204. PubMed PMID: 20949093; PubMed
Central
PMCID: PMC2950859.
6: Xue G, Dong Q, Chen C, Lu Z, Mumford JA, Poldrack RA. Greater neural
pattern
similarity across repetitions is associated with better memory. Science.
2010 Oct
1;330(6000):97-101. Epub 2010 Sep 9. PubMed PMID: 20829453; PubMed Central
PMCID:
PMC2952039.
7: He Q, Xue G, Chen C, Lu Z, Dong Q, Lei X, Ding N, Li J, Li H, Chen C, Li
J,
Moyzis RK, Bechara A. Serotonin transporter gene-linked polymorphic region
(5-HTTLPR) influences decision making under ambiguity and risk in a large
Chinese
sample. Neuropharmacology. 2010 Nov;59(6):518-26. Epub 2010 Jul 24. PubMed
PMID:
20659488; PubMed Central PMCID: PMC2946467.
8: Zhu B, Chen C, Loftus EF, Lin C, He Q, Chen C, Li H, Xue G, Lu Z, Dong Q.
Individual differences in false memory from misinformation: cognitive
factors.
Memory. 2010 Jul;18(5):543-55. PubMed PMID: 20623420.
9: Xue G, Mei L, Chen C, Lu ZL, Poldrack R, Dong Q. Spaced learning enhances
subsequent recognition memory by reducing neural repetition suppression. J
Cogn
Neurosci. 2011 Jul;23(7):1624-33. Epub 2010 Jul 9. PubMed PMID: 20617892.
10: Xue G, Chen C, Lu ZL, Dong Q. Brain Imaging Techniques and Their
Applications
in Decision-Making Research. Xin Li Xue Bao. 2010 Feb 3;42(1):120-137.
PubMed
PMID: 20376329; PubMed Central PMCID: PMC2849100.
11: Mei L, Xue G, Chen C, Xue F, Zhang M, Dong Q. The "visual word form area
" is
involved in successful memory encoding of both words and faces. Neuroimage.
2010
Aug 1;52(1):371-8. Epub 2010 Mar 29. PubMed PMID: 20353828; PubMed Central
PMCID:
PMC2883627.
12: Xue G, Lu Z, Levin IP, Bechara A. The impact of prior risk experiences
on
subsequent risky decision-making: the role of the insula. Neuroimage. 2010
Apr
1;50(2):709-16. Epub 2010 Jan 4. PubMed PMID: 20045470; PubMed Central PMCID:
PMC2828040.
13: Chen C, Xue G, Mei L, Chen C, Dong Q. Cultural neurolinguistics. Prog
Brain
Res. 2009;178:159-71. Review. PubMed PMID: 19874968; PubMed Central PMCID:
PMC2821076.
14: Jiang T, Qiao S, Li J, Cao Z, Gao X, Song Y, Xue G, Dong Q, Chen C.
Effects
of symbol type and numerical distance on the human event-related potential.
Neuropsychologia. 2010 Jan;48(1):201-10. Epub . PubMed PMID: 19751750.
15: Xue G, Lu Z, Levin IP, Weller JA, Li X, Bechara A. Functional
dissociations
of risk and reward processing in the medial prefrontal cortex. Cereb Cortex.
2009
May;19(5):1019-27. Epub 2008 Oct 8. PubMed PMID: 18842669; PubMed Central
PMCID:
PMC2665154.
16: Mei L, Chen C, Xue G, He Q, Li T, Xue F, Yang Q, Dong Q. Neural
predictors of
auditory word learning. Neuroreport. 2008 Jan 22;19(2):215-9. PubMed PMID:
18185111.
17: D'Argembeau A, Xue G, Lu ZL, Van der Linden M, Bechara A. Neural
correlates
of envisioning emotional events in the near and far future. Neuroimage. 2008
Mar
1;40(1):398-407. Epub 2007 Dec 3. PubMed PMID: 18164213; PubMed Central
PMCID:
PMC2782689.
18: Dong Q, Mei L, Xue G, Chen C, Li T, Xue F, Huang S. Sex-dependent
neurofunctional predictors of long-term maintenance of visual word learning.
Neurosci Lett. 2008 Jan 10;430(2):87-91. Epub 2007 Oct 17. PubMed PMID:
18083306.
19: Xue G, Jiang T, Chen C, Dong Q. Language experience shapes early
electrophysiological responses to visual stimuli: the effects of writing
system,
stimulus length, and presentation duration. Neuroimage. 2008 Feb
15;39(4):2025-37. Epub 2007 Nov 28. PubMed PMID: 18053744.
20: Wang Y, Xue G, Chen C, Xue F, Dong Q. Neural bases of asymmetric
language
switching in second-language learners: an ER-fMRI study. Neuroimage. 2007
Apr
1;35(2):862-70. Epub 2007 Feb 26. PubMed PMID: 17324590.
138 张二荃 男 1973年3月 北京生命科学研究所 生命
科学 2004年09月毕业于[美国]加州大学圣地亚哥分校 [美国]诺华制药加州圣地
亚哥研究所 高级博士后研究员
1: Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X, Garcia M, Peters
EC,
Etchegaray JP, Traver D, Schultz PG, Kay SA. High-throughput chemical screen
identifies a novel potent modulator of cellular circadian rhythms and
reveals
CKIα as a clock regulatory kinase. PLoS Biol. 2010 Dec 14;8(12):e1000559.
PubMed
PMID: 21179498; PubMed Central PMCID: PMC3001897.
2: Ko CH, Yamada YR, Welsh DK, Buhr ED, Liu AC, Zhang EE, Ralph MR, Kay SA,
Forger DB, Takahashi JS. Emergence of noise-induced oscillations in the
central
circadian pacemaker. PLoS Biol. 2010 Oct 12;8(10):e1000513. Erratum in: PLoS
Biol. 2010;8(10) doi: 10.1371/annotation/45e0bb8b-69bd-4ba0-bb9e-
6641bce10fc6..
PubMed PMID: 20967239; PubMed Central PMCID: PMC2953532.
3: Zhang EE, Kay SA. Clocks not winding down: unravelling circadian networks
. Nat
Rev Mol Cell Biol. 2010 Nov;11(11):764-76. Review. PubMed PMID: 20966970.
4: Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA,
Sun
X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome
mediates
circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nat Med.
2010
Oct;16(10):1152-6. Epub 2010 Sep 19. PubMed PMID: 20852621; PubMed Central
PMCID:
PMC2952072.
5: Zhang EE, Liu AC, Hirota T, Miraglia LJ, Welch G, Pongsawakul PY, Liu X,
Atwood A, Huss JW 3rd, Janes J, Su AI, Hogenesch JB, Kay SA. A genome-wide
RNAi
screen for modifiers of the circadian clock in human cells. Cell. 2009 Oct
2;139(1):199-210. Epub 2009 Sep 17. PubMed PMID: 19765810; PubMed Central
PMCID:
PMC2777987.
6: Hagihara K, Zhang EE, Ke YH, Liu G, Liu JJ, Rao Y, Feng GS. Shp2 acts
downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during
cerebellar development. Dev Biol. 2009 Oct 1;334(1):276-84. Epub 2009 Jul 25.
PubMed PMID: 19635473; PubMed Central PMCID: PMC2744846.
7: Liu AC, Tran HG, Zhang EE, Priest AA, Welsh DK, Kay SA. Redundant
function of
REV-ERBalpha and beta and non-essential role for Bmal1 cycling in
transcriptional
regulation of intracellular circadian rhythms. PLoS Genet. 2008 Feb
29;4(2):e1000023. PubMed PMID: 18454201; PubMed Central PMCID: PMC2265523.
8: Krajewska M, Banares S, Zhang EE, Huang X, Scadeng M, Jhala US, Feng GS,
Krajewski S. Development of diabesity in mice with neuronal deletion of Shp2
tyrosine phosphatase. Am J Pathol. 2008 May;172(5):1312-24. Epub 2008 Apr 10.
PubMed PMID: 18403587; PubMed Central PMCID: PMC2329840.
9: Pan Y, Carbe C, Powers A, Zhang EE, Esko JD, Grobe K, Feng GS, Zhang X.
Bud
specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF
signaling
during lacrimal gland induction. Development. 2008 Jan;135(2):301-10. Epub
2007
Dec 12. PubMed PMID: 18077586.
10: Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B,
Feng
GS. Deletion of Shp2 in the brain leads to defective proliferation and
differentiation in neural stem cells and early postnatal lethality. Mol Cell
Biol. 2007 Oct;27(19):6706-17. Epub 2007 Jul 23. PubMed PMID: 17646384;
PubMed
Central PMCID: PMC2099234.
11: Liu AC, Welsh DK, Ko CH, Tran HG, Zhang EE, Priest AA, Buhr ED, Singer O,
Meeker K, Verma IM, Doyle FJ 3rd, Takahashi JS, Kay SA. Intercellular
coupling
confers robustness against mutations in the SCN circadian clock network.
Cell.
2007 May 4;129(3):605-16. PubMed PMID: 17482552.
12: Nguyen TV, Ke Y, Zhang EE, Feng GS. Conditional deletion of Shp2
tyrosine
phosphatase in thymocytes suppresses both pre-TCR and TCR signals. J Immunol.
2006 Nov 1;177(9):5990-6. PubMed PMID: 17056523.
13: Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima RG, Muller WJ,
Feng GS.
Conditional deletion of Shp2 in the mammary gland leads to impaired
lobulo-alveolar outgrowth and attenuated Stat5 activation. J Biol Chem. 2006
Nov
10;281(45):34374-80. Epub 2006 Sep 7. PubMed PMID: 16959766; PubMed Central
PMCID: PMC1761121.
14: Dong XP, Li XM, Gao TM, Zhang EE, Feng GS, Xiong WC, Mei L. Shp2 is
dispensable in the formation and maintenance of the neuromuscular junction.
Neurosignals. 2006-2007;15(2):53-63. Epub 2006 Jul 11. PubMed PMID: 16837792.
15: Bard-Chapeau EA, Yuan J, Droin N, Long S, Zhang EE, Nguyen TV, Feng GS.
Concerted functions of Gab1 and Shp2 in liver regeneration and
hepatoprotection.
Mol Cell Biol. 2006 Jun;26(12):4664-74. PubMed PMID: 16738330; PubMed
Central
PMCID: PMC1489129.
16: Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS.
Deletion
of Gab1 in the liver leads to enhanced glucose tolerance and improved
hepatic
insulin action. Nat Med. 2005 May;11(5):567-71. Epub 2005 Apr 10. PubMed
PMID:
15821749.
17: Zhang EE, Chapeau E, Hagihara K, Feng GS. Neuronal Shp2 tyrosine
phosphatase
controls energy balance and metabolism. Proc Natl Acad Sci U S A. 2004 Nov
9;101(45):16064-9. Epub 2004 Nov 1. PubMed PMID: 15520383; PubMed Central
PMCID:
PMC528739.
18: Chen Y, Wen R, Yang S, Schuman J, Zhang EE, Yi T, Feng GS, Wang D.
Identification of Shp-2 as a Stat5A phosphatase. J Biol Chem. 2003 May
9;278(19):16520-7. Epub 2003 Mar 3. PubMed PMID: 12615921.
139 赵晨 男 1974年3月 南京医科大学 生命
科学 2007年07月毕业于[中国]天津医科大学 [美国]美国斯坦福大学医学院
研究科学家,项目首席科学家
1: Zhao C, Vollrath D. mTOR pathway activation in age-related retinal
disease.
Aging (Albany NY). 2011 Apr;3(4):346-7. PubMed PMID: 21483039; PubMed
Central
PMCID: PMC3117448.
2: Iacovelli J, Zhao C, Wolkow N, Veldman P, Gollomp K, Ojha P, Lukinova N,
King
A, Feiner L, Esumi N, Zack DJ, Pierce EA, Vollrath D, Dunaief JL. Generation
of
Cre transgenic mice with postnatal RPE-specific ocular expression. Invest
Ophthalmol Vis Sci. 2011 Mar 14;52(3):1378-83. Print 2011 Mar. PubMed PMID:
21212186; PubMed Central PMCID: PMC3101664.
3: Zhao C, Yasumura D, Li X, Matthes M, Lloyd M, Nielsen G, Ahern K, Snyder
M,
Bok D, Dunaief JL, LaVail MM, Vollrath D. mTOR-mediated dedifferentiation of
the
retinal pigment epithelium initiates photoreceptor degeneration in mice. J
Clin
Invest. 2011 Jan 4;121(1):369-83. doi: 10.1172/JCI44303. Epub 2010 Dec 6.
PubMed
PMID: 21135502; PubMed Central PMCID: PMC3007156.
4: Zhao C, Bellur DL, Lu S, Zhao F, Grassi MA, Bowne SJ, Sullivan LS, Daiger
SP,
Chen LJ, Pang CP, Zhao K, Staley JP, Larsson C. Autosomal-dominant retinitis
pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding
of
U4/U6 snRNAs. Am J Hum Genet. 2009 Nov;85(5):617-27. Epub 2009 Oct 29.
PubMed
PMID: 19878916; PubMed Central PMCID: PMC2775825.
5: Li N, Yang Y, Bu J, Zhao C, Lu S, Zhao J, Yan L, Cui L, Zheng R, Li J,
Tang J,
Zhao K. An autosomal dominant progressive congenital zonular nuclear
cataract
linked to chromosome 20p12.2-p11.23. Mol Vis. 2006 Dec 5;12:1506-10. PubMed
PMID:
17167408.
6: Zhao C, Lu SS, Li ND, Chen WY, Zhao KX. [The clinical manifestation and
linkage analysis in one Chinese family with congenital fibrosis of
extraocular
muscles]. Zhonghua Yan Ke Za Zhi. 2005 Jul;41(7):594-9. Chinese. PubMed PMID:
16080892.
7: Lu SS, Zhao C, Cui Y, Li ND, Zhang XM, Zhao KX. [Novel splice-site
mutation in
the pre-mRNA splicing gene PRPF31 in a Chinese family with autosomal
dominant
retinitis pigmentosa]. Zhonghua Yan Ke Za Zhi. 2005 Apr;41(4):305-11.
Chinese.
PubMed PMID: 15924690.
140 黄亿华 男 1971年10月 中国科学院生物物理研究所 生命
科学 2004年02月毕业于[美国]康奈尔大学 [美国]休斯医学研究所/西南医学中
心 讲师
1: Huang Y, Smith BS, Chen LX, Baxter RH, Deisenhofer J. Insights into pilus
assembly and secretion from the structure and functional characterization of
usher PapC. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7403-7. Epub 2009
Apr
20. PubMed PMID: 19380723; PubMed Central PMCID: PMC2670885.
2: Lin SC, Huang Y, Lo YC, Lu M, Wu H. Crystal structure of the BIR1 domain
of
XIAP in two crystal forms. J Mol Biol. 2007 Sep 28;372(4):847-54. Epub 2007
Jul
21. PubMed PMID: 17698078; PubMed Central PMCID: PMC2039701.
3: Lu M, Lin SC, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H.
XIAP
induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1
dimerization.
Mol Cell. 2007 Jun 8;26(5):689-702. PubMed PMID: 17560374; PubMed Central
PMCID:
PMC1991276.
4: Huang Y, Baxter R, Smith BS, Partch CL, Colbert CL, Deisenhofer J.
Crystal
structure of cryptochrome 3 from Arabidopsis thaliana and its implications
for
photolyase activity. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17701-6.
Epub
2006 Nov 13. PubMed PMID: 17101984; PubMed Central PMCID: PMC1635974.
5: Huang Y, Lu M, Wu H. Antagonizing XIAP-mediated caspase-3 inhibition.
Achilles' heel of cancers? Cancer Cell. 2004 Jan;5(1):1-2. Review. PubMed
PMID:
14749118.
6: Huang Y, Rich RL, Myszka DG, Wu H. Requirement of both the second and
third
BIR domains for the relief of X-linked inhibitor of apoptosis protein
(XIAP)-mediated caspase inhibition by Smac. J Biol Chem. 2003 Dec
5;278(49):49517-22. Epub 2003 Sep 25. PubMed PMID: 14512414.
7: Xu G, Rich RL, Steegborn C, Min T, Huang Y, Myszka DG, Wu H. Mutational
analyses of the p35-caspase interaction. A bowstring kinetic model of
caspase
inhibition by p35. J Biol Chem. 2003 Feb 14;278(7):5455-61. Epub 2002 Nov 27.
PubMed PMID: 12458208.
141 王晓群 男 1972年3月 中国科学院生物物理研究所 生命
科学 2003年06月毕业于[中国]中科院遗传与发育生物学研究所 [美国]加州大学
旧金山分校 副研究员
1: Wang X, Tsai JW, LaMonica B, Kriegstein AR. A new subtype of progenitor
cell
in the mouse embryonic neocortex. Nat Neurosci. 2011 May;14(5):555-61. Epub
2011
Apr 10. PubMed PMID: 21478886; PubMed Central PMCID: PMC3083489.
2: Wang X, Yang N, Uno E, Roeder RG, Guo S. A subunit of the mediator
complex
regulates vertebrate neuronal development. Proc Natl Acad Sci U S A. 2006
Nov
14;103(46):17284-9. Epub 2006 Nov 6. PubMed PMID: 17088561; PubMed Central
PMCID:
PMC1859923.
3: Li X, Qian Q, Fu Z, Wang Y, Xiong G, Zeng D, Wang X, Liu X, Teng S,
Hiroshi F,
Yuan M, Luo D, Han B, Li J. Control of tillering in rice. Nature. 2003 Apr
10;422(6932):618-21. PubMed PMID: 12687001.
4: Mou Z, Wang X, Fu Z, Dai Y, Han C, Ouyang J, Bao F, Hu Y, Li J. Silencing
of
phosphoethanolamine N-methyltransferase results in temperature-sensitive
male
sterility and salt hypersensitivity in Arabidopsis. Plant Cell. 2002
Sep;14(9):2031-43. PubMed PMID: 12215503; PubMed Central PMCID: PMC150753.
142 郑海荣 男 1977年11月 中国科学院深圳先进技术研究院 生命
科学 2006年05月毕业于[美国]科罗拉大学 [美国]加州大学戴维斯分校 项目
科学家
1: Hu X, Zheng H, Kruse DE, Sutcliffe P, Stephens DN, Ferrara KW. A
sensitive
TLRH targeted imaging technique for ultrasonic molecular imaging. IEEE Trans
Ultrason Ferroelectr Freq Control. 2010;57(2):305-16. PubMed PMID: 20178897;
PubMed Central PMCID: PMC2892275.
2: Zheng H, Kruse DE, Stephens DN, Ferrara KW, Sutcliffe P, Gardner E. A
sensitive ultrasonic imaging method for targeted contrast microbubble
detection.
Conf Proc IEEE Eng Med Biol Soc. 2008;2008:5290-3. PubMed PMID: 19163911.
3: Tartis MS, Kruse DE, Zheng H, Zhang H, Kheirolomoom A, Marik J, Ferrara
KW.
Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. J
Control Release. 2008 Nov 12;131(3):160-6. Epub 2008 Jul 29. PubMed PMID:
18718854; PubMed Central PMCID: PMC2756153.
4: Liu L, Zheng H, Williams L, Zhang F, Wang R, Hertzberg J, Shandas R.
Development of a custom-designed echo particle image velocimetry system for
multi-component hemodynamic measurements: system characterization and
initial
experimental results. Phys Med Biol. 2008 Mar 7;53(5):1397-412. Epub 2008
Feb 14.
PubMed PMID: 18296769.
5: Zheng H, Dayton PA, Caskey C, Zhao S, Qin S, Ferrara KW. Ultrasound-
driven
microbubble oscillation and translation within small phantom vessels.
Ultrasound
Med Biol. 2007 Dec;33(12):1978-87. Epub 2007 Sep 27. PubMed PMID: 17900793.
6: Kheirolomoom A, Dayton PA, Lum AF, Little E, Paoli EE, Zheng H, Ferrara
KW.
Acoustically-active microbubbles conjugated to liposomes: characterization
of a
proposed drug delivery vehicle. J Control Release. 2007 Apr 23;118(3):275-84.
Epub 2006 Dec 23. PubMed PMID: 17300849; PubMed Central PMCID: PMC2662343.
7: Zheng H, Mukdadi O, Shandas R. Theoretical predictions of harmonic
generation
from submicron ultrasound contrast agents for nonlinear biomedical
ultrasound
imaging. Phys Med Biol. 2006 Feb 7;51(3):557-73. Epub 2006 Jan 11. PubMed
PMID:
16424581.
8: Zheng H, Mukdadi O, Kim H, Hertzberg JR, Shandas R. Advantages in using
multifrequency excitation of contrast microbubbles for enhancing echo
particle
image velocimetry techniques: initial numerical studies using rectangular
and
triangular waves. Ultrasound Med Biol. 2005 Jan;31(1):99-108. PubMed PMID:
15653236.
9: Zheng H, Mukdadi O, Hertzberg J, Shandas R. Advantages in using
multi-frequency driving ultrasound for optimizing echo particle image
velocimetry
techniques. Biomed Sci Instrum. 2004;40:371-6. PubMed PMID: 15133986.
143 吴允昆 男 1974年12月 中国科学院福建物质结构研究所 生命
科学 2007年08月毕业于[美国]阿巴马伯明翰 [美国]HHMI/德州大学西南医学中
心 博士后研究员
1: Wu Y, Yang Y, Ye S, Jiang Y. Structure of the gating ring from the human
large-conductance Ca(2+)-gated K(+) channel. Nature. 2010 Jul 15;466(7304):
393-7.
Epub 2010 Jun 23. PubMed PMID: 20574420; PubMed Central PMCID: PMC2910425.
2: Tao J, Wu Y, Ron D, Sha B. Preliminary X-ray crystallographic studies of
mouse
UPR responsive protein P58(IPK) TPR fragment. Acta Crystallogr Sect F Struct
Biol
Cryst Commun. 2008 Feb 1;64(Pt 2):108-10. Epub 2008 Jan 31. PubMed PMID:
18259061; PubMed Central PMCID: PMC2374174.
3: Hu J, Wu Y, Li J, Qian X, Fu Z, Sha B. The crystal structure of the
putative
peptide-binding fragment from the human Hsp40 protein Hdj1. BMC Struct Biol.
2008
Jan 22;8:3. PubMed PMID: 18211704; PubMed Central PMCID: PMC2254625.
4: Wu Y, Sha B. Crystal structure of yeast mitochondrial outer membrane
translocon member Tom70p. Nat Struct Mol Biol. 2006 Jul;13(7):589-93. Epub
2006
Jun 11. PubMed PMID: 16767096.
5: Li J, Wu Y, Qian X, Sha B. Crystal structure of yeast Sis1 peptide-
binding
fragment and Hsp70 Ssa1 C-terminal complex. Biochem J. 2006 Sep 15;398(3):
353-60.
PubMed PMID: 16737444; PubMed Central PMCID: PMC1559466.
6: Wu Y, McCombs D, Nagy L, DeLucas L, Sha B. Preliminary X-ray
crystallographic
studies of yeast mitochondrial protein Tom70p. Acta Crystallogr Sect F
Struct
Biol Cryst Commun. 2006 Mar 1;62(Pt 3):265-7. Epub 2006 Feb 24. PubMed PMID:
16511318; PubMed Central PMCID: PMC2197198.
7: Wu Y, Li J, Jin Z, Fu Z, Sha B. The crystal structure of the C-terminal
fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40. J
Mol
Biol. 2005 Mar 4;346(4):1005-11. Epub 2005 Jan 16. PubMed PMID: 15701512.
8: Xie Z, Wu Y, Zhou D, Lin X, Lin S. [Detection of serum total MMP-9 and
its
clinical significance for lung neoplasms.]. Zhongguo Fei Ai Za Zhi. 2002 Oct
20;5(5):338-340. Chinese. PubMed PMID: 21329600.
144 侯百东 男 1971年10月 中国科学院生物物理研究所 生命
科学 2001年07月毕业于[中国]协和医科大学 [美国]加州大学旧金山分校 副
研究专员
1: Ismail AS, Severson KM, Vaishnava S, Behrendt CL, Yu X, Benjamin JL, Ruhn
KA,
Hou B, DeFranco AL, Yarovinsky F, Hooper LV. Gammadelta intraepithelial
lymphocytes are essential mediators of host-microbial homeostasis at the
intestinal mucosal surface. Proc Natl Acad Sci U S A. 2011 May 24;108(21):
8743-8.
Epub 2011 May 9. PubMed PMID: 21555560; PubMed Central PMCID: PMC3102410.
2: Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee LM, Coffman RL,
Bachmann MF, DeFranco AL. Selective utilization of Toll-like receptor and
MyD88
signaling in B cells for enhancement of the antiviral germinal center
response.
Immunity. 2011 Mar 25;34(3):375-84. Epub 2011 Feb 25. PubMed PMID: 21353603;
PubMed Central PMCID: PMC3064721.
3: Rahman AH, Zhang R, Blosser CD, Hou B, Defranco AL, Maltzman JS, Wherry
EJ,
Turka LA. Antiviral memory CD8 T-cell differentiation, maintenance, and
secondary
expansion occur independently of MyD88. Blood. 2011 Mar 17;117(11):3123-30.
Epub
2011 Jan 13. PubMed PMID: 21233312; PubMed Central PMCID: PMC3062314.
4: Hou B, Benson A, Kuzmich L, DeFranco AL, Yarovinsky F. Critical
coordination
of innate immune defense against Toxoplasma gondii by dendritic cells
responding
via their Toll-like receptors. Proc Natl Acad Sci U S A. 2011 Jan
4;108(1):278-83. Epub 2010 Dec 20. PubMed PMID: 21173242; PubMed Central
PMCID:
PMC3017180.
5: Mamchak AA, Sullivan BM, Hou B, Lee LM, Gilden JK, Krummel MF, Locksley
RM,
DeFranco AL. Normal development and activation but altered cytokine
production of
Fyn-deficient CD4+ T cells. J Immunol. 2008 Oct 15;181(8):5374-85. PubMed
PMID:
18832694; PubMed Central PMCID: PMC2657555.
6: Hou B, Reizis B, DeFranco AL. Toll-like receptors activate innate and
adaptive
immunity by using dendritic cell-intrinsic and -extrinsic mechanisms.
Immunity.
2008 Aug 15;29(2):272-82. Epub 2008 Jul 24. PubMed PMID: 18656388; PubMed
Central
PMCID: PMC2847796.
7: Hou B, Eren M, Painter CA, Covington JW, Dixon JD, Schoenhard JA, Vaughan
DE.
Tumor necrosis factor alpha activates the human plasminogen activator
inhibitor-1
gene through a distal nuclear factor kappaB site. J Biol Chem. 2004 Apr
30;279(18):18127-36. Epub 2004 Feb 12. PubMed PMID: 14963043.
145 彭广 女 1978年5月 华中科技大学 生命
科学 2002年05月毕业于[美国]南卡罗来纳大学 [美国]德克萨斯大学 讲师
1: Pan MR, Peng G, Hung WC, Lin SY. Monoubiquitination of H2AX Protein
Regulates
DNA Damage Response Signaling. J Biol Chem. 2011 Aug 12;286(32):28599-607.
Epub
2011 Jun 15. PubMed PMID: 21676867; PubMed Central PMCID: PMC3151101.
2: Peng G, Lin SY. Exploiting the homologous recombination DNA repair
network for
targeted cancer therapy. World J Clin Oncol. 2011 Feb 10;2(2):73-9. PubMed
PMID:
21603316; PubMed Central PMCID: PMC3095467.
3: Liang Y, Gao H, Lin SY, Peng G, Huang X, Zhang P, Goss JA, Brunicardi FC,
Multani AS, Chang S, Li K. BRIT1/MCPH1 is essential for mitotic and meiotic
recombination DNA repair and maintaining genomic stability in mice. PLoS
Genet.
2010 Jan 22;6(1):e1000826. PubMed PMID: 20107607; PubMed Central PMCID:
PMC2809772.
4: Peng G, Lin SY. The linkage of chromatin remodeling to genome maintenance:
contribution from a human disease gene BRIT1/MCPH1. Epigenetics. 2009 Oct
1;4(7):457-61. Epub 2009 Oct 8. Review. PubMed PMID: 19829069.
5: Peng G, Yim EK, Dai H, Jackson AP, Burgt I, Pan MR, Hu R, Li K, Lin SY.
BRIT1/MCPH1 links chromatin remodelling to DNA damage response. Nat Cell
Biol.
2009 Jul;11(7):865-72. Epub 2009 Jun 14. PubMed PMID: 19525936; PubMed
Central
PMCID: PMC2714531.
6: Yim EK, Peng G, Dai H, Hu R, Li K, Lu Y, Mills GB, Meric-Bernstam F,
Hennessy
BT, Craven RJ, Lin SY. Rak functions as a tumor suppressor by regulating
PTEN
protein stability and function. Cancer Cell. 2009 Apr 7;15(4):304-14. PubMed
PMID: 19345329; PubMed Central PMCID: PMC2673492.
7: Peng G, Dixon DA, Muga SJ, Smith TJ, Wargovich MJ. Green tea polyphenol
(-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon
carcinogenesis. Mol Carcinog. 2006 May;45(5):309-19. PubMed PMID: 16508969.
8: Peng G, Wargovich MJ, Dixon DA. Anti-proliferative effects of green tea
polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial
cells.
Cancer Lett. 2006 Jul 18;238(2):260-70. Epub 2005 Sep 12. PubMed PMID:
16157446.
146 张晓明 男 1977年1月 中国科学院上海生命科学研究院 生命
科学 2007年09月毕业于[法国]巴黎第6大学 [法国]巴斯德研究所 研究助理
1: Freire T, Zhang X, Dériaud E, Ganneau C, Vichier-Guerre S, Azria E,
Launay O,
Lo-Man R, Bay S, Leclerc C. Glycosidic Tn-based vaccines targeting dermal
dendritic cells favor germinal center B-cell development and potent antibody
response in the absence of adjuvant. Blood. 2010 Nov 4;116(18):3526-36. Epub
2010
Aug 18. PubMed PMID: 20720186.
2: Zhang X, Majlessi L, Deriaud E, Leclerc C, Lo-Man R. Coactivation of Syk
kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory
properties of neutrophils. Immunity. 2009 Nov 20;31(5):761-71. Epub 2009 Nov
12.
PubMed PMID: 19913447.
3: Deng Q, Mancini-Bourgine M, Zhang X, Cumont MC, Zhu R, Lone YC, Michel ML.
Hepatitis B virus as a gene delivery vector activating foreign antigenic T
cell
response that abrogates viral expression in mouse models. Hepatology. 2009
Nov;50(5):1380-91. PubMed PMID: 19821533.
4: Zhang X, Deriaud E, Jiao X, Braun D, Leclerc C, Lo-Man R. Type I
interferons
protect neonates from acute inflammation through interleukin 10-producing B
cells. J Exp Med. 2007 May 14;204(5):1107-18. Epub 2007 May 7. PubMed PMID:
17485512; PubMed Central PMCID: PMC2118587.
147 钟治晖 男 1977年2月 四川大学 生命
科学 2007年05月毕业于[美国]罗切斯特大学 [美国]罗切斯特大学 讲师
1: Zhong Z, Winkler EA, Zlokovic BV. Microhemorrhages: undetectable but
clinically meaningful the question persists. Amyotroph Lateral Scler. 2011
May;12(3):231-2; author reply 233-4. Epub 2011 Mar 17. PubMed PMID: 21413850.
2: Guo H, Barrett TM, Zhong Z, Fernández JA, Griffin JH, Freeman RS,
Zlokovic BV.
Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen
activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1
signaling
pathway. Mol Neurodegener. 2011 Feb 3;6:13. PubMed PMID: 21291561; PubMed
Central
PMCID: PMC3042387.
3: Zhong Z, Wang Y, Guo H, Sagare A, Fernández JA, Bell RD, Barrett TM,
Griffin
JH, Freeman RS, Zlokovic BV. Protein S protects neurons from excitotoxic
injury
by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt
pathway
through its sex hormone-binding globulin-like region. J Neurosci. 2010 Nov
17;30(46):15521-34. PubMed PMID: 21084607; PubMed Central PMCID: PMC3012432.
4: Zhu D, Wang Y, Singh I, Bell RD, Deane R, Zhong Z, Sagare A, Winkler EA,
Zlokovic BV. Protein S controls hypoxic/ischemic blood-brain barrier
disruption
through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. Blood.
2010
Jun 10;115(23):4963-72. Epub 2010 Mar 26. PubMed PMID: 20348395; PubMed
Central
PMCID: PMC2890172.
5: Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan
M,
Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N,
Castellino
FJ, Stojanovic K, Cleveland DW, Zlokovic BV. Activated protein C therapy
slows
ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor
neurons
and microglia cells. J Clin Invest. 2009 Nov;119(11):3437-49. doi:
10.1172/JCI38476. Epub 2009 Oct 19. PubMed PMID: 19841542; PubMed Central
PMCID:
PMC2769191.
6: Deane R, LaRue B, Sagare AP, Castellino FJ, Zhong Z, Zlokovic BV.
Endothelial
protein C receptor-assisted transport of activated protein C across the
mouse
blood-brain barrier. J Cereb Blood Flow Metab. 2009 Jan;29(1):25-33. Epub
2008
Oct 8. PubMed PMID: 18841163; PubMed Central PMCID: PMC2895315.
7: Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic
K,
Sagare A, Boillee S, Cleveland DW, Zlokovic BV. ALS-causing SOD1 mutants
generate
vascular changes prior to motor neuron degeneration. Nat Neurosci. 2008
Apr;11(4):420-2. Epub 2008 Mar 16. PubMed PMID: 18344992; PubMed Central
PMCID:
PMC2895310.
8: Chibalin AV, Leng Y, Vieira E, Krook A, Björnholm M, Long YC, Kotova
O, Zhong
Z, Sakane F, Steiler T, Nylén C, Wang J, Laakso M, Topham MK, Gilbert M,
Wallberg-Henriksson H, Zierath JR. Downregulation of diacylglycerol kinase
delta
contributes to hyperglycemia-induced insulin resistance. Cell. 2008 Feb
8;132(3):375-86. PubMed PMID: 18267070.
9: Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting
PJ,
Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV.
Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med.
2007
Sep;13(9):1029-31. Epub 2007 Aug 12. PubMed PMID: 17694066; PubMed Central
PMCID:
PMC2936449.
10: Cheng T, Petraglia AL, Li Z, Thiyagarajan M, Zhong Z, Wu Z, Liu D,
Maggirwar
SB, Deane R, Fernández JA, LaRue B, Griffin JH, Chopp M, Zlokovic BV.
Activated
protein C inhibits tissue plasminogen activator-induced brain hemorrhage.
Nat
Med. 2006 Nov;12(11):1278-85. Epub 2006 Oct 29. PubMed PMID: 17072311.
148 张永安 男 1972年4月 中国科学院水生生物研究所 生命
科学 2001年06月毕业于[中国]中国科学院水生生物研究所 [美国]宾夕法尼亚大
学 研究助理
1: Zhang YA, Salinas I, Oriol Sunyer J. Recent findings on the structure and
function of teleost IgT. Fish Shellfish Immunol. 2011 Apr 3. [Epub ahead of
print] PubMed PMID: 21466854.
2: Zhang YA, Salinas I, Li J, Parra D, Bjork S, Xu Z, LaPatra SE,
Bartholomew J,
Sunyer JO. IgT, a primitive immunoglobulin class specialized in mucosal
immunity.
Nat Immunol. 2010 Sep;11(9):827-35. Epub 2010 Aug 1. PubMed PMID: 20676094.
3: Liu Y, Cocka L, Okumura A, Zhang YA, Sunyer JO, Harty RN. Conserved
motifs
within Ebola and Marburg virus VP40 proteins are important for stability,
localization, and subsequent budding of virus-like particles. J Virol. 2010
Mar;84(5):2294-303. Epub 2009 Dec 23. PubMed PMID: 20032189; PubMed Central
PMCID: PMC2820906.
4: Zhang YA, Hikima J, Li J, LaPatra SE, Luo YP, Sunyer JO. Conservation of
structural and functional features in a primordial CD80/86 molecule from
rainbow
trout (Oncorhynchus mykiss), a primitive teleost fish. J Immunol. 2009 Jul
1;183(1):83-96. Epub 2009 Jun 17. PubMed PMID: 19535623.
5: McCarthy SE, Johnson RF, Zhang YA, Sunyer JO, Harty RN. Role for amino
acids
212KLR214 of Ebola virus VP40 in assembly and budding. J Virol. 2007
Oct;81(20):11452-60. Epub 2007 Aug 15. PubMed PMID: 17699576; PubMed Central
PMCID: PMC2045517.
6: Li J, Barreda DR, Zhang YA, Boshra H, Gelman AE, Lapatra S, Tort L,
Sunyer JO.
B lymphocytes from early vertebrates have potent phagocytic and microbicidal
abilities. Nat Immunol. 2006 Oct;7(10):1116-24. Epub 2006 Sep 17. PubMed
PMID:
16980980.
149 谢震 男 1976年8月 清华大学 生命
科学 2006年12月毕业于[美国]内华达大学拉斯维加斯分校 [美国]麻省理工学院
博士后
1: Leisner M, Bleris L, Lohmueller J, Xie Z, Benenson Y. Rationally designed
logic integration of regulatory signals in mammalian cells. Nat Nanotechnol.
2010
Sep;5(9):666-70. Epub 2010 Jul 11. PubMed PMID: 20622866; PubMed Central
PMCID:
PMC2934882.
2: Xie Z, Liu SJ, Bleris L, Benenson Y. Logic integration of mRNA signals by
an
RNAi-based molecular computer. Nucleic Acids Res. 2010 May;38(8):2692-701.
Epub
2010 Mar 1. PubMed PMID: 20194121; PubMed Central PMCID: PMC2860122.
3: Xie Z, Zhang ZL, Hanzlik S, Cook E, Shen QJ. Salicylic acid inhibits
gibberellin-induced alpha-amylase expression and seed germination via a
pathway
involving an abscisic-acid-inducible WRKY gene. Plant Mol Biol. 2007
Jun;64(3):293-303. Epub 2007 Mar 28. PubMed PMID: 17390108.
4: Xie Z, Zhang ZL, Zou X, Yang G, Komatsu S, Shen QJ. Interactions of two
abscisic-acid induced WRKY genes in repressing gibberellin signaling in
aleurone
cells. Plant J. 2006 Apr;46(2):231-42. PubMed PMID: 16623886.
5: Xie Z, Ruas P, Shen QJ. Regulatory networks of the phytohormone abscisic
acid.
Vitam Horm. 2005;72:235-69. Review. PubMed PMID: 16492473.
6: Xie Z, Zhang ZL, Zou X, Huang J, Ruas P, Thompson D, Shen QJ. Annotations
and
functional analyses of the rice WRKY gene superfamily reveal positive and
negative regulators of abscisic acid signaling in aleurone cells. Plant
Physiol.
2005 Jan;137(1):176-89. Epub 2004 Dec 23. PubMed PMID: 15618416; PubMed
Central
PMCID: PMC548849.
7: Zhang ZL, Xie Z, Zou X, Casaretto J, Ho TH, Shen QJ. A rice WRKY gene
encodes
a transcriptional repressor of the gibberellin signaling pathway in aleurone
cells. Plant Physiol. 2004 Apr;134(4):1500-13. Epub 2004 Mar 26. PubMed PMID:
15047897; PubMed Central PMCID: PMC419826.
150 晏为力 男 1973年1月 西南交通大学 生命
科学 2006年06月毕业于[美国]肯塔基大学 [美国]奥本大学 助理教授
1: Yan W, Chen WC, Liu Z, Huang L. Bryostatin-I: a dendritic cell stimulator
for
chemokines induction and a promising adjuvant for a peptide based cancer
vaccine.
Cytokine. 2010 Dec;52(3):238-44. Epub 2010 Sep 24. PubMed PMID: 20869878.
2: Wei J, Yan W, Li X, Ding Y, Tai HH. Thromboxane receptor alpha mediates
tumor
growth and angiogenesis via induction of vascular endothelial growth factor
expression in human lung cancer cells. Lung Cancer. 2010 Jul;69(1):26-32.
Epub
2009 Oct 23. PubMed PMID: 19853959.
3: Wei J, Yan W, Li X, Chang WC, Tai HH. Activation of thromboxane receptor
alpha
induces expression of cyclooxygenase-2 through multiple signaling pathways
in
A549 human lung adenocarcinoma cells. Biochem Pharmacol. 2007 Sep
1;74(5):787-800. Epub 2007 Jun 14. PubMed PMID: 17632087; PubMed Central
PMCID:
PMC1995664.
4: Huang X, Yan W, Gao D, Tong M, Tai HH, Zhan CG. Structural and functional
characterization of human microsomal prostaglandin E synthase-1 by
computational
modeling and site-directed mutagenesis. Bioorg Med Chem. 2006 May
15;14(10):3553-62. Epub 2006 Jan 24. PubMed PMID: 16439136.
5: Yan W, Ding Y, Tai HH. 14-3-3zeta interacts with human thromboxane
receptors
and is involved in the agonist-induced activation of the
extracellular-signal-regulated kinase. Biochem Pharmacol. 2006 Feb
28;71(5):624-33. Epub 2006 Jan 4. PubMed PMID: 16413928.
6: Yan W, Tai HH. Glycogen synthase kinase-3 phosphorylation, T-cell factor
signaling activation, and cell morphology change following stimulation of
thromboxane receptor alpha. J Pharmacol Exp Ther. 2006 Apr;317(1):267-74.
Epub
2005 Dec 13. PubMed PMID: 16352701.
151 常兴 男 1978年9月 中国科学院上海生命科学研究院 生命
科学 2006年07月毕业于[美国]俄亥俄州立大学 [美国]耶鲁大学 博士后
1: Chang X, Liu F, Wang X, Lin A, Zhao H, Su B. The kinases MEKK2 and MEKK3
regulate transforming growth factor-β-mediated helper T cell
differentiation.
Immunity. 2011 Feb 25;34(2):201-12. Epub 2011 Feb 17. PubMed PMID: 21333552;
PubMed Central PMCID: PMC3073014.
2: Wang X, Chang X, Facchinetti V, Zhuang Y, Su B. MEKK3 is essential for
lymphopenia-induced T cell proliferation and survival. J Immunol. 2009 Mar
15;182(6):3597-608. PubMed PMID: 19265138; PubMed Central PMCID: PMC2923428.
3: Zuo T, Wang L, Morrison C, Chang X, Zhang H, Li W, Liu Y, Wang Y, Liu X,
Chan
MW, Liu JQ, Love R, Liu CG, Godfrey V, Shen R, Huang TH, Yang T, Park BK,
Wang
CY, Zheng P, Liu Y. FOXP3 is an X-linked breast cancer suppressor gene and
an
important repressor of the HER-2/ErbB2 oncogene. Cell. 2007 Jun
29;129(7):1275-86. Epub 2007 Jun 14. Erratum in: Cell. 2008 Aug 8;134(3):546.
PubMed PMID: 17570480; PubMed Central PMCID: PMC1974845.
4: May KF Jr, Chang X, Zhang H, Lute KD, Zhou P, Kocak E, Zheng P, Liu Y.
B7-deficient autoreactive T cells are highly susceptible to suppression by
CD4(+)CD25(+) regulatory T cells. J Immunol. 2007 Feb 1;178(3):1542-52.
PubMed
PMID: 17237403.
5: Joshi PS, Liu JQ, Wang Y, Chang X, Richards J, Assarsson E, Shi FD,
Ljunggren
HG, Bai XF. Cytokine-induced killer T cells kill immature dendritic cells by
TCR-independent and perforin-dependent mechanisms. J Leukoc Biol. 2006
Dec;80(6):1345-53. Epub 2006 Sep 22. PubMed PMID: 16997856.
6: Chang X, Chen L, Wen J, Godfrey VL, Qiao G, Hussien Y, Zhang J, Gao JX.
Foxp3
controls autoreactive T cell activation through transcriptional regulation
of
early growth response genes and E3 ubiquitin ligase genes, independently of
thymic selection. Clin Immunol. 2006 Dec;121(3):274-85. Epub 2006 Aug 30.
PubMed
PMID: 16945588.
7: Chang X, Zheng P, Liu Y. FoxP3: a genetic link between immunodeficiency
and
autoimmune diseases. Autoimmun Rev. 2006 Jul;5(6):399-402. Epub 2005 Dec 7.
Review. PubMed PMID: 16890893.
8: Kocak E, Lute K, Chang X, May KF Jr, Exten KR, Zhang H, Abdessalam SF,
Lehman
AM, Jarjoura D, Zheng P, Liu Y. Combination therapy with anti-CTL antigen-4
and
anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity.
Cancer
Res. 2006 Jul 15;66(14):7276-84. PubMed PMID: 16849577.
9: Li O, Chang X, Zhang H, Kocak E, Ding C, Zheng P, Liu Y. Massive and
destructive T cell response to homeostatic cue in CD24-deficient lymphopenic
hosts. J Exp Med. 2006 Jul 10;203(7):1713-20. Epub 2006 Jun 12. PubMed PMID:
16769998; PubMed Central PMCID: PMC2118348.
10: Richards JO, Chang X, Blaser BW, Caligiuri MA, Zheng P, Liu Y. Tumor
growth
impedes natural-killer-cell maturation in the bone marrow. Blood. 2006 Jul
1;108(1):246-52. Epub 2006 Mar 23. PubMed PMID: 16556890; PubMed Central
PMCID:
PMC1895835.
11: Chang X, Gao JX, Jiang Q, Wen J, Seifers N, Su L, Godfrey VL, Zuo T,
Zheng P,
Liu Y. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective
thymopoiesis. J Exp Med. 2005 Oct 17;202(8):1141-51. PubMed PMID: 16230479;
PubMed Central PMCID: PMC2213221.
12: Gao JX, Chang X, Zheng X, Wen J, Yin L, Du P, Zheng P, Liu Y. A new role
for
CD28 in the survival of autoreactive T cells in the periphery after chronic
exposure to autoantigen. Int Immunol. 2004 Oct;16(10):1403-9. Epub 2004 Aug
16.
PubMed PMID: 15314039.
13: Zheng X, Gao JX, Chang X, Wang Y, Liu Y, Wen J, Zhang H, Zhang J, Liu Y,
Zheng P. B7-CD28 interaction promotes proliferation and survival but
suppresses
differentiation of CD4-CD8- T cells in the thymus. J Immunol. 2004 Aug
15;173(4):2253-61. PubMed PMID: 15294937.
152 田梅 女 1972年7月 浙江大学 生命
科学 2004年03月毕业于[日本]国立群马大学 [美国]德克萨斯大学 助理教授
40 articles, see at:
http://www.uthouston.edu/dotAsset/2201504.pdf |