c*******g
发帖数: 695 | 1 或者和pk部门合作很多
分析phase III的数据
想上来听听经验
需要学NONMEM么？
thanks | l*******n
发帖数: 19 | 2 As long as you can write the explicit models for the Pop PK, you can use
statistical software to fit models so Nonmem is not necessary. For example,
there is an example for One-Compartment Pharmacokinetic Model in SAS manual
for sas nlmixed. One advantage of Nonmem is that it contains some standard
modules (like macros) for PK.
In my view, Pop-PK may serve two purposes depending on the data used: if
early stage data are used, Pop-PK may provide guidance for later study
designs; if Phase I |
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