x******n 发帖数: 173 | 1 "
1. From a small pilot study in six elderly females after hip fracture, the
mean
hematocrit was 32.3%. In the same institution, in 32 healthy elderly females
, the
mean hematocrit was 33.5%.
2. Two previous studies tested different doses of the new drug in other
patient
groups. In those studies, the placebo group showed no change in hematocrit.
The
treated group showed changes of 2.5% to 5%.
These data taken together suggest that we can expect a change of 0% in the
placebo
treated group, with treatment group changes lying in the range 2.5 to 5%.
Thus, a
conservative estimate of the possible effect of the new drug in elderly
females might
be in the range 2.0% to 2.4%. Such increases would be of real value to the
patient.
"
这个2% to 2.4%是如何算出来的? 谢谢 |
Y******Y 发帖数: 8753 | 2 看来看去不觉得这个是sample size calculation... |
a****g 发帖数: 8131 | 3 这是其中的一段话
后面还有size,variance这样的info
我就是想知道这个2%-2.4%的difference range是如何确定的
【在 Y******Y 的大作中提到】 : 看来看去不觉得这个是sample size calculation...
|
Y******Y 发帖数: 8753 | 4 用的是什么test?
【在 a****g 的大作中提到】 : 这是其中的一段话 : 后面还有size,variance这样的info : 我就是想知道这个2%-2.4%的difference range是如何确定的
|
a****g 发帖数: 8131 | 5 2-sample t with equal variance
【在 Y******Y 的大作中提到】 : 用的是什么test?
|