t****8
发帖数: 1 | 3 原文在这里。确实有一定效果，但那个实验里副作用也很大。今天报道的这个实验，似
乎没什么副作用。剂量也许不一样。
https://www.nejm.org/doi/full/10.1056/NEJMoa2007016
SAFETY
Summary of Adverse Events.
A total of 32 patients (60%) reported adverse events during follow-up (Table
2). The most common adverse events were increased hepatic enzymes, diarrhea
, rash, renal impairment, and hypotension. In general, adverse events were
more common in patients receiving invasive ventilation. A total of 12
patients (23%) had serious adverse events. The most common serious adverse
events — multiple-organ-dysfunction syndrome, septic shock, acute kidney
injury, and hypotension — were reported in patients who were receiving
invasive ventilation at baseline.
Four patients (8%) discontinued remdesivir treatment prematurely: one
because of worsening of preexisting renal failure, one because of multiple
organ failure, and two because of elevated aminotransferases, including one
patient with a maculopapular rash. |
