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v********a
发帖数: 646 | 3 点击fulltext，只有这么多内容：
http://cancerdiscovery.aacrjournals.org/content/5/7/OF20.abstra
Chimeric antigen receptors (CAR) link antigen-binding domains with T-cell
signaling domains and represent potential anticancer agents. However, only
CARs targeting CD19 in hematologic malignancies have demonstrated
significant clinical efficacy. To identify the mechanisms underlying the
poor efficacy of CARs targeting other tumor antigens, Long and colleagues
compared the in vivo antitumor activity of CD19 CAR T ... 阅读全帖 |
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m******j
发帖数: 5079 | 4 发信人: asqwasqw (qwasqwas), 信区: SanDiego
标 题: 房屋出租1BB $1200/month, 7月底
发信站: BBS 未名空间站 (Fri Jun 7 23:30:18 2013, 美东)
房屋出租1BB $1200/month, 7月底开始
帮房东出租的
地址在9535 genesee ave
全新装修，租期一年
有意者请站内信
谢谢
相关情况请看链接
http://sandiego.craigslist.org/csd/apa/3851418820.html
小区现在市场价格是1235, 我去年租的价格是1200所以保持不变 |
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j****x
发帖数: 1704 | 5 http://web.yyjjb.com:8080/html/2014-04/18/content_207700.htm
编者按：本栏目2013年研发盘点的最后一篇毫无疑问落到肿瘤免疫治疗这一大热领域。
在4个多月的写作过程中，作者翻阅上百篇国内外文献，走访中国学者，围绕该疗法的
发现历史到最新思维范式，结合行业并购、研发挫败种种事件回答了这样一个问题——
为什么每个人都想成为这项技术的领跑者。其间不乏许多曲折和悲欢的情节。更惊喜的
是，作者手绘插图，为全文增添色彩。30年后，肿瘤免疫疗法强势回归公众视野，经过
漫长探索之后，必将有更多像结尾讲述的琳达那样的病人，从这一革命性医药技术中获
益。
作者的话：
一个很关键、悬而未解的问题是怎样运用生物标记物依照个性化医疗的原理来挑选最合
适接受肿瘤免疫治疗的病人。这是从事转化科学研究的同行们关注的。
在过去的12个月，对我和许多专注癌症研究的同行们是一段激动人心的旅程。2013年9
月，在上海，我们阿斯利康亚洲及新兴市场创新医药部将公司第一个在中国发现的临床
前候选药物送入全球肿瘤研发管线上。该项目从启动到候选药物投资决定只用了20个月
时... 阅读全帖 |
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f**x
发帖数: 4325 | 6 纽约警察根本不管交通。如果纽约交规真的严格执行，政府一年得暴增$1bb收入 |
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o*****p
发帖数: 2977 | 7
公认日本海军比英国差远了。
二战日本海军实力是否超过英国？
http://www.zhihu.com/question/21740349
著作权归作者所有。
商业转载请联系作者获得授权，非商业转载请注明出处。
作者：Norman Karma
链接：http://www.zhihu.com/question/21740349/answer/28224716
来源：知乎
先给结论吧，二战旧日本帝国海军（下简称IJN）在整个太平洋战争期间的实力都未超
过英国皇家海军（下简称RN），除去在部分装备上的优势之外，基本可以说是全方位的
落后。
题主提的这个问题限制在了二战期间两支海上力量的比较，题主给出了一些比较重要的
方面，还有一些方面我自认为比较重要，因此一起讨论。
文中的一些缩写：
BB：战列舰 BC：战列巡洋舰 CV：航空母舰 CVE：护航航母 CL：轻型巡洋舰 DD：驱逐
舰 SS：攻击潜艇
• 战争物资
•
首先可能题主有一点误解的地方在于，海军航空兵以及航空母舰成为远洋海军的中坚力
量成为共识，是在中途岛海战之后。
在二战开始之前，大概是从186... 阅读全帖 |
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f**x
发帖数: 4325 | 8 谁也没禁止你炒啊，你投$1bb自己炒呗
总指望着别人算个屁本事，是男人的想到就自己去做 |
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A********e
发帖数: 354 | 9 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
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r**u
发帖数: 42 | 10 Reveal Navigation Options
The Wall Street Journal
show search
Close Search
Submit Search
850 189
POLITICS AND POLICY
Push to Tax ‘529’ Plans Stokes Debate
Obama Touts Proposal as Means to Restructure Student Aid, but Critics See
Challenges for Middle Class
ENLARGE
By JOSH MITCHELL
Updated Jan. 22, 2015 4:04 p.m. ET
240 COMMENTS
President Barack Obama ’s push to start taxing college-saving accounts,
including the popular “529” accounts, would affect millions of Americans
who are stashing money fo... 阅读全帖 |
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z*****a
发帖数: 3809 | 11 【 以下文字转载自 Investment 讨论区 】
发信人: rtyu (ccaarr), 信区: Investment
标 题: Obama提案对529 plan征税
发信站: BBS 未名空间站 (Fri Jan 23 11:43:54 2015, 美东)
Reveal Navigation Options
The Wall Street Journal
show search
Close Search
Submit Search
850 189
POLITICS AND POLICY
Push to Tax ‘529’ Plans Stokes Debate
Obama Touts Proposal as Means to Restructure Student Aid, but Critics See
Challenges for Middle Class
ENLARGE
By JOSH MITCHELL
Updated Jan. 22, 2015 4:04 p.m. ET
240 COMMENTS
President Barack Obama ’s push to sta... 阅读全帖 |
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p*******g
发帖数: 2976 | 12 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
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d*******g
发帖数: 114 | 13 有1bb的buyback plan，跌了这么多了，会出来救市吗？ |
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N*****e
发帖数: 2573 | 14 没几个愿意和你老婆孩子合租的吧，
你不要找APT,找那些房东的house，每层都是一个单独的1BB,或２ＢＢ，会便宜不少 |
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O***n
发帖数: 13127 | 16 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
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y***r
发帖数: 65 | 18 天才少年Josh Beckett终于发飙，
9IP, 2Hit, 1BB, 11K, 115Pitch Complete Game Shutout
开始看他狂飙快球我还有点替他担心，不过他的control确实没得说，
fastball, breaking ball, changeup,。。。看得我目瞪口呆
Zambrano其实也不错了，可惜面对Lowell犯了个错误，另外这个人有点
过于情绪化了。
这个系列打到现在，Cubs的打线算是超常发挥了，另外他们的运气也好一点，
不过Marlins很有韧性，如果他们的先发投手能挺住，大翻盘也不是没有可能。
当然Cubs的机会大的多，Prior加Wood，就是有一个被打爆（可能性<50%),还
有另一个呢，而且他们似乎很善于在Wrighly Field打往家跑。
期待明天的比赛。。。 |
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s****r
发帖数: 5546 | 19 被打得东倒西歪，都10 hits 1BB了，怎么就是不爆呢 |
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z******n
发帖数: 1223 | 20 胡撩也弄了2/3 1BB 2run
不过还是2 LOB
曾记得去年WS中某一场（大约是最后一场？）胡撩高接抵挡神勇无比啊 |
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A**d
发帖数: 13310 | 21 别睁眼说瞎话，您9:13PST发帖子时候已经是第六局了。即使top5那也是
4+ inning 2hits, 1BB.还是那句话：无知阳极扇子最好闭嘴，别在这儿
上蹿下跳显摆你们有多无知。 |
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s****r
发帖数: 5546 | 22 不作弊的话做的就是10M签下Ben Sheets这么漂亮的生意：
0IP 8H 10R 9ER 1BB 1HR |
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m*z
发帖数: 2356 | 23 投出NO-Hitter后的Doc
34K, only 1BB的Lee
还有Best Baseball Team in the League的Philly |
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S**********e
发帖数: 852 | 24 昨天Zito不算无解吧
5.2IP 6H 1BB |
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z******n
发帖数: 1223 | 25 2007 ALCS GM5,3:1领先的克利夫兰请了Josh Beckett的老相好Danielle Peck现场唱国
歌，Beckett此战8IP,5H,1R,1BB,11K第二次力克CC Sabathia。
红袜最终七场胜出进军WS |
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z******n
发帖数: 1223 | 26 9月2日在Fenway,7IP, 0ER, 4H, 4K, 4BB打败Lackey (7.1IP, 3ER, 7H, 1BB, 5K)
老虎3:0胜
接下来两场红袜打败了Scherzer（2:1），外加一场20:4. |
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f*****8
发帖数: 69 | 27 Freeland目前总体比Marquez表现优异，这个无可厚非。
只不过Marquez也是挺不错的。尤其是七月以后的表现。要说星期一的game 163. 他的
表现也不能算爆。从数据看4.2IP 5H 4R 2ER 2BB 9K 2HR，其中第一个Belinger的HR的
破坏性，跟之前跟投手沟通不畅，导致Max Muncy三振不死也有很大关系。
这场而言，5IP 7H 2ER 1BB 5K 1HR的表现，也不算是拖后腿了。开场手冷，保送了耶
律齐，然后被打2安打，让耶律齐得分。再就是一个83mph的curveball正中Aguilar的下
怀，打中HR。其他的时候来看，他的表现还是可以可圈可点的。
总体而言，Marquez相对于Freeland, 三振能力更强，但是有些细节和关键球的处理不
如Freeland。但是也不能掩盖他是个很好的投手苗子的潜力。 |
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E******n
发帖数: 6647 | 28 11/2
吃了5个rasberry bagel和10个tuffle巧克力
11/3
早饭：1鸡蛋+1/3cup walnut+1/3cup cereal+4巧克力+150ml牛奶
午饭：酸辣白菜+鸡肉
下午喝了很多咖啡w/伴侣
游泳40min 1000yard+8min abs
晚上：半盒豆腐w/2块腐乳+1bb carrot+3/4cup walnut+1口面包+1苹果 |
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i********r
发帖数: 1153 | 29 first of all your preflop raise is too small, there are already a few
limpers, and you raise to 3BB, you are just inviting them to call you, but
your hand is not a big pot hand even it's suited. It also doesn't play well
in multiway pot. Your little raise didn't do anything, it didn't define your
hand well, it built up a pot that your hand isn't good for and it didn't
limited the field. You need to raise it big, 3.5BB + 1BB per limper is the
standard online raise, I assume you need to raise a li |
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l**********t
发帖数: 269 | 30 小对现在是我的major leak 来的。有时候扔不掉牌。 还在努力的练习。
我打NL25。 凡事按最简单不头痛的打法走。
preflop
22--99 有人raise, 对方short stack. 跟到3bb. 对方full stack. 跟到4bb. 每
加一个跟进的人，可以放宽1bb.
22--99 没人raise. just call at all position except button. Raise 3bb on
button.
1010. 看心情。
JJ. major leak. very aggressive preflop. will try to buy the blinds.
flop
22-1010. hit set, aggressive in most cases will slow play on safe board.
usually try to get all in. don't hit set, try to check down. run as soon
as facing any aggressio |
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y********n
发帖数: 2063 | 31 It sucks. Just feel I throw 300bucks into the water without any reason.
Yep. It influences my game a lot since that bad play.
Will play less those 100chips token game.
Should say I am Ok with it.
The game I posted, I just lose my head, did not see the opponent's stack
size. Normally, I will take that game without any questions.
Only 1bb in the pot. Why I need to risk 6.5bb to get it.
super
swings |
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y********n
发帖数: 2063 | 32 I virtually lose all coin flip.
double the 1st finisher(he comes into the final table with less than 1BB) at
least 4 times.
double the 2nd finisher at least 4 times.
double 4th finisher 2 times.
everytime, pair vs 2 overs, I lose
2 over vs pair, I lose
ace * vs KJ , I lose
KJ vs Ace *, I lose
final hand, I have ace jack suited, SB pushes allin, I have around 11bb(68k chips, blinds 6k/3k level). I
called, SB has tt. I lose. Recall from this morning, I maybe shoul |
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p*****s
发帖数: 33 | 33 Last night on Fulltilt,
Caught 2 ppls bluffing allins, both time they got lucky. Both hands have
about 80+BB.
Hand 1:
I have AQo at Botton-1. UTG raise to 2BB, 4 callers to me, I limp in,
botton raise all in 90BB
All fold to me, since Botton has used that several times when multiple pps
limp in 1BB or 2BB, I felt good to call with 60BB in my hand. Botton shows
45s, I lost.
Hand 2:
QQ UTG. Raise to 4BB, Botton and Botton-1 calls.
Flop 78K rainbow, bet 10BB to see where I stand, got called by b |
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h*******s
发帖数: 3932 | 34 first it's a raise not a re-raise.
a raise needs to add at least the bet amount (which is at least 1BB). a re-
raise needs to add at least the raise amount.
the exception is allin. and if allin amount is not enough to be a raise, it'
s not considered as a raise to reopen another raise possibility.
the
to
since
multiple
most
Does |
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s*********k
发帖数: 1989 | 35 来自主题: TexasHoldem版 - 今赢一小手 Hehe, Thx.
After won this, I went to play two 24+1(one for 200+9 and the other
for 500+35) and one 70+4 (for 200+9). All got kicked out.
So I threw 140$ back immediately(in one hour).
That is one my biggest problem. When I have $$ or win some, I got loose eyes
one bankroll.
One great experience yesterday is that I fell below 1BB (I had 225 only, BB=
300) after two all-in heavy punches (I was chip lead before that. Both hand
I had Ax, x>=J). I got AA and 4x(two guys in and there is ante) and then |
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s*********k
发帖数: 1989 | 36 Sigh. Same here.
I was in 70+4 for 200+16 seat(starting chip=300, BB=30, Turbo game).
I was at BB. The SB call all in (all the guys ahead folded). I had A6. the
guy had 73 (I know he tried to steal my BB). Flop 774, leave zero chance to
me. It is surely ugly. I was left with 30 (1BB) and soon kicked out. |
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n******1
发帖数: 4742 | 37 不知道那位兄弟,long term 是赢是输,打了多少首牌了,bb/100是多少
他打100 or200 nl? 1bb/100+bonus 每月定量打,收入就算不错了
gus |
|
f*****g
发帖数: 15860 | 38 正常业余玩家(一周玩几次，多桌，非天天上班型)，一年也就是100K手左右，rush多一
点。
1BB/100(1000BB)的话，其实非常有限的收入，加上bonus+rake翻一倍，200NL也就是一
年一万以内。
扑克对于绝大多数人，都是指望不上的，只是娱乐别输光了裤衩而已。
象fcf那样的太凤毛鳞角了。 |
|
y********n
发帖数: 2063 | 39 i am not joking.
My over aggressive style costs me a lot. My win rate down a lot recently.
Really frustrating. Winning rate goes as low as 1bb/100 hands. Can not
compare with your 10BB/100 hands.
I guess 10bb/100 is really really hot from any means.
|
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s*********k
发帖数: 1989 | 40 ye, just 1BB is done. Could be the guy dose not pay too much attention or
play too many table at a same time. |
|
s*********k
发帖数: 1989 | 41 Nice Job. I do play RUSH but not much. My RUSh has been long flat (1BB or
2BB/100). Just pick up this week frankly.
Anyone likes to share your experience to intercept these numbers or post
links
which explains how to diguest these? Thanks, |
|
s*********k
发帖数: 1989 | 42 hehe, I ovserve one ME short out BTW. (600+buy-in and 16 seats are handed out)
. When 17 players left, there are 4 bigleaders(100+K). All the others are
chicken (many <3BB). The last guy gets washed out
with 72o at BB (one chip leader allin with anyhand w/ 84o won by pair of 4).
At that time, 5ppl has less than 1BB left. |
|
y********n
发帖数: 2063 | 43 Do not know. Sounds you are too tight. I check my cash full ring games, it
shows vpip is 24%, pfr is 23%.
But my final result is not good. Only 1bb/100.
Maybe I need grind more to check if my winrate can go up a little.
difference |
|
W********m
发帖数: 7793 | 44 goes help me!!! I am back down to 1bb/100 hand.. i need some of your mad
skillz. NL 100 is unkind to me or maybe i am just not good enough for it yet
... This win rate is pathetic...
my bank roll is not broke, but my spirit is definitely at the edge.... |
|
W********m
发帖数: 7793 | 45 I can't play more than 2 windows effectively. I play rush mainly for the
volumn. Regular table is too slow for me certainly. I do agree with you
that rush is getting more more close to regular game with hud around. So the
sheer volumn itself is nice. Even though my win rate has not been good
lately, I think I still have potential.
I just need to improve my game further. 打牌就是逆水行舟， 你不进步，就被别
人超过.
But I still believe not many people have significant edge over me at NL100, but the 1bb/100 hand win |
|
