H*****e
发帖数: 120 | 1 Wow, on the top list!
Well, I never expect to be on the top list. This reason is that I am not
here very often. Also apologize to those are discussing about the topic and
expect me to give my opinion.
I believe that the previous title regarding to someone retract her paper is
misleading. So it is necessary to clear some issue and have an opportunity
to draw more discussion. Now back to the stem cell issue not the Amy or
Carla although name may be mentioned but please ignore my own personal
... 阅读全帖 |
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c****t
发帖数: 19049 | 2 ScienceDaily (July 9, 2011) — For the past decade, researchers have tried
to reprogram the identity of all kinds of cell types. Heart cells are one of
the most sought-after cells in regenerative medicine because researchers
anticipate that they may help to repair injured hearts by replacing lost
tissue. Now, researchers at the Perelman School of Medicine at the
University of Pennsylvania are the first to demonstrate the direct
conversion of a non-heart cell type into a heart cell by RNA transfer... 阅读全帖 |
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O******e
发帖数: 4845 | 3 ☆─────────────────────────────────────☆
yuuli (听，...听) 于 (Thu Nov 16 23:23:06 2006) 提到:
http://www.cell.com/content/article/fulltext?uid=PIIS0092867406012256&highlight=polymerase
Cell, Vol 127, 317-327, 20 October 2006
Role of the Sigma Factor in Transcription Initiation in the Absence of Core
RNA Polymerase
Hsin-Hsien蔋su,1 Kuei-Min蔆hung,1 Tsung-Ching蔆hen,1 and Ban-Yang蔆hang1,*
1 Institute of Biochemistry, National Chung-Hsing University, Taichung 40227
, Taiwan, Republic of China
从第二个图... 阅读全帖 |
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m******1
发帖数: 19713 | 4 Expanding on previous research providing proof-of-principle that human stem
cells can be genetically engineered into HIV-fighting cells, a team of UCLA
researchers has now demonstrated that these cells can actually attack HIV-
infected cells in a living organism.
The study, published April 12 in the journal PLoS Pathogens, demonstrates
for the first time that engineering stem cells to form immune cells that
target HIV is effective in suppressing the virus in living tissues in an
animal model, sa... 阅读全帖 |
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r***e
发帖数: 2539 | 5 Thank everyone for the discussion!
As pineseed pointed out, too many topics were discussed here.
But my personal interests are:
1. what is the cell origin of different type of lung cancers?
2. does cell origin or mutation decide tumor types?
3. how to model different type of lung cancer?
HGTPase, it seems you are working in this field (more lung development than
lung cancer?), and I hope you can give your opinions. We can also discuss in
private mails for technique details.
1. ... 阅读全帖 |
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M**a
发帖数: 4816 | 6 26 January, 2012 Volume 1, Issue 1EditorialMore than the Sum of Its Parts p1
Boyana Konforti
Full Text | PDF (62 kb)
More than the Sum of Its Parts
Boyana Konforti
Editor, Cell Reports
Welcome to the first issue of Cell Reports, a new open-access journal that
covers all of biology with a focus on high-quality short papers. There are,
of course, other open-access journals—in fact, quite a number have launched
just in recent years (and there will almost certainly be more to follow)—
though few hav... 阅读全帖 |
|
M**a
发帖数: 4816 | 7 26 January, 2012 Volume 1, Issue 1EditorialMore than the Sum of Its Parts p1
Boyana Konforti
Full Text | PDF (62 kb)
More than the Sum of Its Parts
Boyana Konforti
Editor, Cell Reports
Welcome to the first issue of Cell Reports, a new open-access journal that
covers all of biology with a focus on high-quality short papers. There are,
of course, other open-access journals—in fact, quite a number have launched
just in recent years (and there will almost certainly be more to follow)—
though few hav... 阅读全帖 |
|
m*******r
发帖数: 202 | 8 Cell Cycle. 2005 Mar;4(3):453-5. Epub 2005 Mar 7.
Cell cycle markers for live cell analyses.
Easwaran HP, Leonhardt H, Cardoso MC.
SourceMax Delbrück Center for Molecular Medicine, Berlin, Germany.
Abstract
Many cellular processes are regulated by cell cycle dependent changes in
protein dynamics and localization. Studying these changes in vivo requires
methods to distinguish the different cell cycle stages. Here we demonstrate
the use of DNA Ligase I fused to DsRed1 as an in situ marker to ident... 阅读全帖 |
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s*******7
发帖数: 399 | 9 那个Structure不是Cell真正的子刊来的（意思是由Cell Press代出版，但不是Cell自
己主办的杂志）。
Cell Press的杂志和Nature一样，也有2种，一种“嫡系”（自己主办）的，就像
Nature里面nc，nn，nm，ni，ncb，nsmb等等这种。另一种是“旁系”（代理出版）
的，比如Nature里面的中国人搞的aps，cell research等等。
Nature系列好判断，只要某杂志前面带Nature，人人都知道，这是Nature的主力“中央
军”（Nature自己主办），是Nature真正的子刊。
Cell里面“中央军”（cell自己办的杂志，可以说是Cell真正的子刊）按首刊时间顺序
有Cell，Neuron，Immunity，Molecular Cell，Developmental Cell，Cancer Cell，
Cell Metabolism，Cell Host & Microbe，Cell Stem Cell ，以及最新的Cell
Reports。
其他几种杂志，有些是Elsevier搞过来委托cell出版社出版的，
其中就包括楼主说的s... 阅读全帖 |
|
w********h
发帖数: 12367 | 10 Solar shakeout continues: Q-Cells to file for bankruptcy
By Ucilia Wang Apr. 2, 2012, 10:47am PT No Comments
Q-Cells was once the largest solar cell maker in the world. Now the company
says on Monday it will be filing for bankruptcy, which makes it the latest
example of the solar industries’ turmoil.
The German company has been in trouble for some time and tried several cost-
reduction measures to stay in business. The decline has been a long-time
coming and made worse by the particularly bruta... 阅读全帖 |
|
d*****r
发帖数: 2583 | 11 发信人: JAMBAHLA (金巴拉), 信区: TsinghuaCent
标 题: 清华大学，华中农大教授入选Cell子刊编委
发信站: 水木社区 (Thu Nov 24 09:45:05 2011), 站内
生物通 11-23 万纹
今年Cell出版社推出了全新的开放获取期刊：Cell Reports，这是自2007年Cell出
版社新增Cell Stem Cell和Cell Host & Microbe两份期刊后的又一重要新成员。这一
期刊致力于报道整个生命科学领域的高质量研究成果，主要集中于短小，单个观点的文
章——当然也接受标准长度的论文，因此这一期刊命名为Reports。
近期Cell Reports公布了最新的编委组名单，其中有4位华裔科学家入选，其中包
括华中农业大学“千人计划”教授阮一骏，清华大学医学院教授颜宁，以及来自凯特林
癌症中心的时松海研究员，和加州大学伯克利分校助理教授何琳。
《Cell》杂志创刊于1976年，以发表具有重要意义的原创性科研报告为主，现已成
为世界自然科学研究领域最著名的期刊之一，除此之外，Cell出版社目前还陆续发行了
十几种姊妹刊，在各... 阅读全帖 |
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H*****e
发帖数: 120 | 12 Well, nothing need to be hidden. If some experimental discussion is needed,
we can communicate privately.
From academic view, there are several questions that need to be answered (
Sorry my chinese input is very slow):
1.Whether stem cell is cancer stem cell is an issue. I read so many
literature that people are using tissue stem cell marker for identify cancer
stem cells. Frankly, I reject all of them, manuscript or grant application.
2.Whether there is Lung stem cell is rather unclear (coul... 阅读全帖 |
|
s******r
发帖数: 2876 | 13 实际上我觉得Pax7细胞就不应该叫做stem cell，
叫个其他名字，比如progenitor cell。
大家都管自己的细胞叫干细胞，实际上只不过是炒作概念，
做development的都说自己是做的干细胞了。
TA cells是个stem cell 的动力学问题. 对于fast turnover tisue以及slow turnover
tissue,我认为其dynamic应该是不同的。fast turnover tissue 来说，quiescent
stem cell-->proliferating TA cells——》committed progenitors_-->terminal
differentiated cells 这样的过程有利于stem cell快速扩增。但对于很多slow
turnover tissue, 比如，肌肉，骨，这样的TA population在生理状况下是检测不到的
。当然对slow turnover tissue的 stem cell dynamic的研究本来就很少。
关于multipotential是否该是stem cell的定义，最好的... 阅读全帖 |
|
J****S
发帖数: 15 | 14 Pls contact: d******[email protected] for more information
We are seeking several highly motivated individuals with mammalian cell
culture experience, and a background in molecular and/or cellular biology
and/or biochemistry to join or lead our Cell Line Development Team. The
successful candidate will have cell culture/cell line development experience
in an industrial setting.
The successful candidate will be involved in the development and
characterization of recombinant cell culture processes fr... 阅读全帖 |
|
t****g
发帖数: 120 | 15 我最近一直在做一个gene的knockdown cell line。 用的是open biosystems的pLKO.1
system。 try了三个不同的cell lines，发现一个普遍问题： 细胞养了一个月之后我
就不同程度地丢失了最开始的knockdown. 我会详细解释一下我的做法，请大家帮我看
看问题到底在哪儿：
day 1: plate cancer cells for transduction
day 2: add virus/polybrene to cells (half volume of media) in the morning;
6hr later, add the other half volume of media to dilute polybrene
day 4: change to selection medium
day 5: in my case, usually the cells have become confluent before the effect
of antibiotics became obvious. I had t... 阅读全帖 |
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w********r
发帖数: 1431 | 16 最近没事，看了几片beta cell的paper，
发现关于beta cell stem/progenitor cell的争论还挺热闹的。
顶尖杂志上经常你来我往灌水争论这个progenitor cell到底存在不存在。
04年Melton DA组的一片nature用了Insulin的reporter mice做了genetic tracing，说
新生的beta cell都是从existing beta cell长出来的，
但08年Xiaobo Xu的Cell比较清楚的证明了progenitor cell的存在，
11年3月的Simon R. Smukler的cell stem cell和说这个细胞是存在的，而且直接说
Melton当年nature paper里面的老鼠有问题。不过看了11年CSC的文章从submit到接受
用了差不多两年，不知道是不是业内反对派的能量太大啊？
CSC配了一片previews，看上去也是各种抹稀泥，各打五十大板，
说progenitor cell是存在的，但是differentiated beta cell自己duplicate也是存在
的。
我一外行... 阅读全帖 |
|
E**********t
发帖数: 56 | 17 Xuebiao Yao, Dasheng Li and Gang Pei recently wrote an essay to Nature
Review in MCB Which is entitled “In focus: molecular and cell biology
research in China”. Here is the link: http://www.nature.com/nrm/journal/v14/n9/full/nrm3638.html In this article, they discussed the past, present and future of molecular and cell biology research in China. One part which interested me is the key MCB discoveries in China. Although most of the work are nice and likely solid work, few of them are breakthrough... 阅读全帖 |
|
z****u
发帖数: 1007 | 18 TA cells是个stem cell 的动力学问题. 对于fast turnover tisue以及slow turnover
tissue,我认为其dynamic应该是不同的。fast turnover tissue 来说，quiescent
stem cell-->proliferating TA cells——》committed progenitors_-->terminal
differentiated cells 这样的过程有利于stem cell快速扩增。但对于很多slow
turnover tissue, 比如，肌肉，骨，这样的TA population在生理状况下是检测不到的
。当然对slow turnover tissue的 stem cell dynamic的研究本来就很少。
关于multipotential是否该是stem cell的定义，最好的回答是Pax7+ satellite cells
for muscle. 它完全只contribute to skeletal muscle而没有别的任何potential ,
除此以外，它的其它特性都完全的复合ste... 阅读全帖 |
|
d**l
发帖数: 1546 | 19 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: dial (四八佳人), 信区: Pharmaceutical
标 题: 诚聘cell culture scientist(中国苏州）
发信站: BBS 未名空间站 (Thu Sep 20 19:37:45 2012, 美东)
我在这帮老板招个人。我们公司现在在中国需要一个人做cell culture. 如感兴趣请发
信到m********[email protected]
Position summary:
We are looking for a scientist with a strong cellular biology background and
expertise in adherent cell culture techniques. Responsibilities include
tissue culture of mammalian stem cells and maintenance of all cell culture
related equipment and laboratory reage... 阅读全帖 |
|
t***q
发帖数: 9 | 20 Protein & Cell为由高等教育出版社、中国科学院北京生命科学研究院和中国生物物理
学会联合创办的英文学术月刊，由Springer负责海外发行，自2010年1月起，每月以纸
质印刷和在线两种形式出版，于2010年11月进入Medline数据检索系统。
Protein & Cell由饶子和院士担任主编，编委会由70余位该领域国内外知名专家、学者
组成。 Protein & Cell报道生命科学和生物医学的前沿热点，特别关注蛋白质和细胞
研究的最新学术成果和发展动向，发表的文章类型包括研究论文、综述、新闻评论、人
物故事等，具体报道学科领域包括：生物物理学、细胞生物学、分子生物学、蛋白质学
、生物化学、发育生物学、结构生物学、免疫生物学、微生物学、遗传学、神经科学和
肿瘤学等，旨在打造一个学术水平高、可读性强、具有全球影响力的生命科学期刊品牌
更多信息，请访问http://www.protein-cell.org。
现 Protein & Cell编辑部面向海内外招贤纳士，欢迎志同道合者的加盟！
职位职能：
全职科学编辑
职位描述：
1． 协助责任编辑进行每期组稿、约稿的联系... 阅读全帖 |
|
E*****m
发帖数: 25615 | 21 http://news.discovery.com/human/embryonic-stem-cells-trials.html?print=true
First Human Embryonic Stem Cell Trial Begins
The landmark trial could one day lead to a breakthrough in the treatment of
spinal cord injuries.
Thu Oct 14, 2010 11:50 AM ET | content provided by Karin Zeitvogel, AFP
Doctors have begun the first tests of human embryonic stem cells in patients
, treating a man with spinal cord injuries in a landmark trial of the
controversial process, the Geron Corporation said Monday.
The ... 阅读全帖 |
|
h********n
发帖数: 4079 | 22 Why the concept of CSC is important in basic cancer research? To me, the
key question is: does a solid tumor (such as lung, liver, etc) arise from a
differentiated epithelial cell, or it arise from a tissue specific stem cell
/progenitor cell.
tissue specific stem cell/progenitor cell ---> differentiated epithelial
cell.
CSC--->differentiated cancer cells (with different potency).
Think of the comparison between these cells, especially the cancer vs normal
cells.
As to cancer cell lines, some o... 阅读全帖 |
|
s******r
发帖数: 2876 | 23 不过自从iPS发明以后，我觉得solid tumor也可能起源于分化细胞。
Why the concept of CSC is important in basic cancer research? To me, the
key question is: does a solid tumor (such as lung, liver, etc) arise from a
differentiated epithelial cell, or it arise from a tissue specific stem cell
/progenitor cell.
tissue specific stem cell/progenitor cell ---> differentiated epithelial
cell.
CSC--->differentiated cancer cells (with different potency).
Think of the comparison between these cells, especially the cancer vs normal... 阅读全帖 |
|
c******r
发帖数: 3778 | 24 实验嘛，不行就自己发明啦。
比如可以先回答cell contact是否required for somatic cell induced stem cell
proliferation.
可以把somatic cell先做你想做的处理，然后放在culture里，跟stem cell用0.3um的
膜分开。这样如果stem cell proliferation增加了，那说明是soluble factor，在
culture medium里面。可以尝试用不同的antibody block。这样可以找到是什么factor。
如果stem cell不增加，那么可以把stem cell用CFSE之类的marker标记了，和处理过的
somatic cell混养，这样如果刺激stem cell proliferation，那么说明cell contact
很重要。那么可以focus on cell surface molecules，试试不同的knock down，看看
有没有哪个能block这个过程。
当然，注意做好controls。
具体实验设计要看情况，我的意思是你这个问题很有意思，不能因为... 阅读全帖 |
|
h******y
发帖数: 1374 | 25 Induction of functional hepatocyte-like cells from mouse fibroblasts by
defined factors
Nature (2011) doi:10.1038/nature10116
Received 23 August 2010 Accepted 15 April 2011 Published online 11 May 2011
Affiliations
Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell
Biology, Shanghai Institutes for
Biological Sciences, Chinese Academy for Sciences, Yueyang Road 320, 200031
Shanghai, China
Pengyu Huang, Zhiying He, Shuyi Ji, Huawang Sun, Changcheng Liu, Xin Wang &
Lijian Hui
... 阅读全帖 |
|
h***y
发帖数: 59 | 26 Protein & Cell为由高等教育出版社、中国科学院北京生命科学研究院和中国生物物理
学会联合创办的英文学术月刊，由Springer负责海外发行，自2010年1月起，每月以纸
质印刷和在线两种形式出版，于2010年11月进入Medline数据检索系统。
Protein & Cell由饶子和院士担任主编，编委会由70余位该领域国内外知名专家、学者
组成。 Protein & Cell报道生命科学和生物医学的前沿热点，特别关注蛋白质和细胞
研究的最新学术成果和发展动向，发表的文章类型包括研究论文、综述、新闻评论、人
物故事等，具体报道学科领域包括：生物物理学、细胞生物学、分子生物学、蛋白质学
、生物化学、发育生物学、结构生物学、免疫生物学、微生物学、遗传学、神经科学和
肿瘤学等，旨在打造一个学术水平高、可读性强、具有全球影响力的生命科学期刊品牌
更多信息，请访问http://www.protein-cell.org。
现 Protein & Cell编辑部面向海内外招贤纳士，欢迎志同道合者的加盟！
职位职能：
全职科学编辑
职位描述：
1． 协助责任编辑进行每期组稿、约稿的联系... 阅读全帖 |
|
d**l
发帖数: 1546 | 27 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: dial (四八佳人), 信区: Pharmaceutical
标 题: 诚聘cell culture scientist(中国苏州）
发信站: BBS 未名空间站 (Thu Sep 20 19:37:45 2012, 美东)
我在这帮老板招个人。我们公司现在在中国需要一个人做cell culture. 如感兴趣请发
信到m********[email protected]
Position summary:
We are looking for a scientist with a strong cellular biology background and
expertise in adherent cell culture techniques. Responsibilities include
tissue culture of mammalian stem cells and maintenance of all cell culture
related equipment and laboratory reage... 阅读全帖 |
|
d**l
发帖数: 1546 | 28 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: dial (四八佳人), 信区: Pharmaceutical
标 题: 诚聘cell culture scientist(中国苏州）
发信站: BBS 未名空间站 (Thu Sep 20 19:37:45 2012, 美东)
我在这帮老板招个人。我们公司现在在中国需要一个人做cell culture. 如感兴趣请发
信到m********[email protected]
Position summary:
We are looking for a scientist with a strong cellular biology background and
expertise in adherent cell culture techniques. Responsibilities include
tissue culture of mammalian stem cells and maintenance of all cell culture
related equipment and laboratory reage... 阅读全帖 |
|
h***y
发帖数: 59 | 29 Protein & Cell为由高等教育出版社、中国科学院北京生命科学研究院和中国生物物理
学会联合创办的英文学术月刊，由Springer负责海外发行，自2010年1月起，每月以纸
质印刷和在线两种形式出版，于2010年11月进入Medline数据检索系统。
Protein & Cell由饶子和院士担任主编，编委会由70余位该领域国内外知名专家、学者
组成。 Protein & Cell报道生命科学和生物医学的前沿热点，特别关注蛋白质和细胞
研究的最新学术成果和发展动向，发表的文章类型包括研究论文、综述、新闻评论、人
物故事等，具体报道学科领域包括：生物物理学、细胞生物学、分子生物学、蛋白质学
、生物化学、发育生物学、结构生物学、免疫生物学、微生物学、遗传学、神经科学和
肿瘤学等，旨在打造一个学术水平高、可读性强、具有全球影响力的生命科学期刊品牌
更多信息，请访问http://www.protein-cell.org。
现 Protein & Cell编辑部面向海内外招贤纳士，欢迎志同道合者的加盟！
职位职能：
全职科学编辑
职位描述：
1． 协助责任编辑进行每期组稿、约稿的联系... 阅读全帖 |
|
d**l
发帖数: 1546 | 30 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: dial (四八佳人), 信区: Pharmaceutical
标 题: 诚聘cell culture scientist(中国苏州）
发信站: BBS 未名空间站 (Thu Sep 20 19:37:45 2012, 美东)
我在这帮老板招个人。我们公司现在在中国需要一个人做cell culture. 如感兴趣请发
信到m********[email protected]
Position summary:
We are looking for a scientist with a strong cellular biology background and
expertise in adherent cell culture techniques. Responsibilities include
tissue culture of mammalian stem cells and maintenance of all cell culture
related equipment and laboratory reage... 阅读全帖 |
|
t********1
发帖数: 18 | 31 买房后发现自己condo的楼顶上有两个Cell phone antenna。听说每年condo associate
能收$20,000，相应homeowner的condo fee每月少~$50。
刚开始搬进来的时候我就觉得有点不对，有时感觉耳边有响声、晚上睡不着，或半夜总
醒，有时又感觉很困。我开始以为刚换了个新地方，还没习惯过来。但这种情况一直持
续，没见太大变化，我以为是自己工作压力大的原因，就尽量调节来自工作的压力。又
过了一段时间，有时觉得头疼。这所有的感觉都是以前没有的，至少没有长时间持续有
这些症状。最近发现楼顶上有两个Cell phone antenna。上网一查吓了大跳，长期可能
引发Cancer，后面有些链接。
我给我们condo的manager打电话，他很显然不愿意跟我谈搬走这两个antennas。
Trustee的人都不住这儿，而且这里大多是租客，大部分homeowner都不住这里。请问各
位有什么好建议，怎么能把这antennas弄走？这种情况我该怎么处理？
另外，不知这种把cell phone antenna装在居民楼顶是否违法？有没有理由sue 电信公
司或... 阅读全帖 |
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t********1
发帖数: 18 | 32 买房后发现自己condo的楼顶上有两个Cell phone antenna。听说每年condo associate
能收$20,000，相应homeowner的condo fee每月少~$50。
刚开始搬进来的时候我就觉得有点不对，有时感觉耳边有响声、晚上睡不着，或半夜总
醒，有时又感觉很困。我开始以为刚换了个新地方，还没习惯过来。但这种情况一直持
续，没见太大变化，我以为是自己工作压力大的原因，就尽量调节来自工作的压力。又
过了一段时间，有时觉得头疼。这所有的感觉都是以前没有的，至少没有长时间持续有
这些症状。最近发现楼顶上有两个Cell phone antenna。上网一查吓了大跳，长期可能
引发Cancer，后面有些链接。
我给我们condo的manager打电话，他很显然不愿意跟我谈搬走这两个antennas。
Trustee的人都不住这儿，而且这里大多是租客，大部分homeowner都不住这里。请问各
位有什么好建议，怎么能把这antennas弄走？这种情况我该怎么处理？
另外，不知这种把cell phone antenna装在居民楼顶是否违法？有没有理由sue 电信公
司或... 阅读全帖 |
|
d**********u
发帖数: 4124 | 33 ☆─────────────────────────────────────☆
CaMKII (不作postdog) 于 (Sat Nov 8 01:18:35 2008) 提到:
发信人: CaMKII (不作postdog), 信区: Biology
标 题: 北大邓宏魁发了一篇Cell Stem Cell
发信站: BBS 未名空间站 (Fri Nov 7 22:09:29 2008)
做的也是iPSC，看来和国外跟得很紧啊。
北大今年ms很牛，除了程和平之前发的一篇Cell，程还有一篇Nature被接受，另外尚永
丰也有一篇Cell被接受。
Cell Stem Cell, Volume 3, Issue 5, 475-479, 6 November 2008
doi:10.1016/j.stem.2008.10.002
Two Supporting Factors Greatly Improve the Efficiency of Human iPSC
Generation
Yang Zhao1, 4, Xiaolei Yin1, 2, 4, Han Qin1,... 阅读全帖 |
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h********n
发帖数: 4079 | 34 I am so glad to read your thought. I would like to discuss a little more.
to 1: the term of CSC is controversy, but what if I say: "In lung adenocarcinoma, there is a population of tumor cells whose potency (in vivo) is much higher than other population in the same tumor. It is important to study this population of cells. How about we call it tumor initiating cell?"
what is your opinion to my above thought?
to 4: I don't agree with you on this point. Most lung cancer model use SPC or CCSP or C... 阅读全帖 |
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w********r
发帖数: 1431 | 35 in the case of beta cell, I think it is more than "literally" argument ...
Existing beta cell dublication and progenitor cell differentiation are
totally two concepts. For the name of muscle satellite cell/primary myoblast
/muscle stem cell, we are also confused. So we call them "muscle progenitor
cell" in our recent paper... lol
exist
work
correct one here though), on muscle satellite/stem cells, about 6 ys ago,
one prominent stem cell biologist(I am sure that many on this board knows
him) we... 阅读全帖 |
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Q**********u
发帖数: 1616 | 36 68核心期刊里面不带cell report elife玩
The Nature Index includes primary research articles published in a group (n=
68; see Section 4.0)
of high-quality science journals. The journals included in the Nature Index
are selected by a panel of active scientists, independently of NPG. The
selection process reflects researchers’ perceptions of journal quality,
rather than using quantitative measures such as Impact Factor. It is
intended that the list of journals amounts to a reasonably consensual upper
echelon ... 阅读全帖 |
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H*****l
发帖数: 702 | 37
5.5%是nrel测定的效率？好像为了organic solar cell的效率，那票人和NREL的嘴仗都
打上IEEE spectrum了
就算是5.5%，cell尺寸多大？是不是用的point contact那种为了破纪录作的特别小的
cell area?
把它high volume化还要多久？
solar cell要high volume cheap的生产
还有，谁告诉你 silicon 才15%？连suntech都量产17%的solar cell
而且对于silicon solar cell而言，cpv化是大势所趋
PARC&Sol Focus现在在合作通过CPV把13-15%的cheap cell 达到30%的efficiency
CPV和epi thin film silicon solar cell的结合比普通crystalline base silicon
solar cell更容易
提示你一点，review solar cell的历史，你会发现long live silicon solar cell!不
仅在AM1.5G下，silicon比3-5 group先做到2 |
|
H*****l
发帖数: 702 | 38
5.5%是nrel测定的效率？好像为了organic solar cell的效率，那票人和NREL的嘴仗都
打上IEEE spectrum了
就算是5.5%，cell尺寸多大？是不是用的point contact那种为了破纪录作的特别小的
cell area?
把它high volume化还要多久？
solar cell要high volume cheap的生产
还有，谁告诉你 silicon 才15%？连suntech都量产17%的solar cell
而且对于silicon solar cell而言，cpv化是大势所趋
PARC&Sol Focus现在在合作通过CPV把13-15%的cheap cell 达到30%的efficiency
CPV和epi thin film silicon solar cell的结合比普通crystalline base silicon
solar cell更容易
提示你一点，review solar cell的历史，你会发现long live silicon solar cell!不
仅在AM1.5G下，silicon比3-5 group先做到2... 阅读全帖 |
|
d**l
发帖数: 1546 | 39 我在这帮老板招个人。我们公司现在在中国需要一个人做cell culture. 如感兴趣请发
信到m********[email protected]
Position summary:
We are looking for a scientist with a strong cellular biology background and
expertise in adherent cell culture techniques. Responsibilities include
tissue culture of mammalian stem cells and maintenance of all cell culture
related equipment and laboratory reagents. In addition to cell culture, the
candidate will aid in preparation of material for use in ongoing human
clinical trials. Familiarity with cGMP pro... 阅读全帖 |
|
f**e
发帖数: 3343 | 40 【 以下文字转载自 Joke 讨论区 】
发信人: biokold (kold), 信区: Joke
标 题: 转贴：《范博中Cell》， 苦逼千老写照 (转载)
发信站: BBS 未名空间站 (Tue Jun 24 00:35:12 2014, 美东)
发信人: dongHei200 (医学小子), 信区: Biology
标 题: 转贴：《范博中Cell》， 苦逼千老写照
发信站: BBS 未名空间站 (Mon Jun 23 13:33:06 2014, 美东)
范博做完实验回office，实验室刚来的rotation student、一块搬砖的千老俱各欢喜。
正待烧锅做饭，只见他老板Dr. 胡，手里拿着一盒miniprep柱和一瓶培养基，走了进来
。范博向他作揖，坐下。Dr. 胡道：“我自倒运，把个博后位置给与你这现世宝 ，历
年以来，不知累了我多少。如今不知因我积了甚么德，带挈你中了个PLoS ONE ，我所
以带个培养基来贺你。”范博唯唯连声，叫rotation student把柱和培养基收起来，在
实验台边上坐着。Rotation student自和小本科生在细胞间换m... 阅读全帖 |
|
f**********r
发帖数: 18251 | 41 【 以下文字转载自 Joke 讨论区 】
发信人: biokold (kold), 信区: Joke
标 题: 转贴：《范博中Cell》， 苦逼千老写照 (转载)
发信站: BBS 未名空间站 (Tue Jun 24 00:35:12 2014, 美东)
发信人: dongHei200 (医学小子), 信区: Biology
标 题: 转贴：《范博中Cell》， 苦逼千老写照
发信站: BBS 未名空间站 (Mon Jun 23 13:33:06 2014, 美东)
范博做完实验回office，实验室刚来的rotation student、一块搬砖的千老俱各欢喜。
正待烧锅做饭，只见他老板Dr. 胡，手里拿着一盒miniprep柱和一瓶培养基，走了进来
。范博向他作揖，坐下。Dr. 胡道：“我自倒运，把个博后位置给与你这现世宝 ，历
年以来，不知累了我多少。如今不知因我积了甚么德，带挈你中了个PLoS ONE ，我所
以带个培养基来贺你。”范博唯唯连声，叫rotation student把柱和培养基收起来，在
实验台边上坐着。Rotation student自和小本科生在细胞间换m... 阅读全帖 |
|
d*****u
发帖数: 71 | 42 这是一个杂志发给我的邀请，但是由于自己没有这么多精力去做这个事。现贴在这个，
看相关领域的谁有兴趣去申请。对在攒绿卡条件的人是个机会。能否申请到看个人运气
和背景了。。。祝成功！！！
Dear Dr. xx,
Warm greetings from J SciMed Central!
We introduce ourselves as JSM Cell, it is an Open access journal publishes
peer-reviewed novel research in the field of Cell Science and Research. Our
journal focuses on the Stem cell biology, Cancer biology, Chromosomal
biology, Molecular biology etc.
JSM Cell welcomes qualified researchers and experts as Editorial Board
Members from Cell research scient... 阅读全帖 |
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f**********r
发帖数: 18251 | 43 【 以下文字转载自 Joke 讨论区 】
发信人: biokold (kold), 信区: Joke
标 题: 转贴：《范博中Cell》， 苦逼千老写照 (转载)
发信站: BBS 未名空间站 (Tue Jun 24 00:35:12 2014, 美东)
发信人: dongHei200 (医学小子), 信区: Biology
标 题: 转贴：《范博中Cell》， 苦逼千老写照
发信站: BBS 未名空间站 (Mon Jun 23 13:33:06 2014, 美东)
范博做完实验回office，实验室刚来的rotation student、一块搬砖的千老俱各欢喜。
正待烧锅做饭，只见他老板Dr. 胡，手里拿着一盒miniprep柱和一瓶培养基，走了进来
。范博向他作揖，坐下。Dr. 胡道：“我自倒运，把个博后位置给与你这现世宝 ，历
年以来，不知累了我多少。如今不知因我积了甚么德，带挈你中了个PLoS ONE ，我所
以带个培养基来贺你。”范博唯唯连声，叫rotation student把柱和培养基收起来，在
实验台边上坐着。Rotation student自和小本科生在细胞间换m... 阅读全帖 |
|
p******d
发帖数: 3737 | 44 I guess these are two different concepts. CSC is to discuss if there are
some unique cells in the tumor that can self-renewal and give rise to
other tumor cells. The question you raised here is about the cell origin
of tumor, which is related with CSC, however not the same concept.Take a
look at this pape:
Crypt stem cells as the cells-of-origin of intestinal cancer.
Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den
Born M, Danenberg E, Clarke AR, Sansom OJ, Clevers H.
Some ... 阅读全帖 |
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d*p
发帖数: 534 | 46 I am talking about general cell therapy. Oncogenic is only one part of the
safety issue. For example, one major concern of T cell therapy is over-
activated T cell might cause autoimmune disease, which is a very common
problem in stem cell and organ transplant, including cancer immunotherapy.
Rosenberg, a big name in cancer immune therapy, killed one patient due to
the infused Her2/neu targeting T cell were activated in lung.
Stem cell therapy actually only account for a small part of cell thera... 阅读全帖 |
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G*****h
发帖数: 320 | 47 自己并不是做这块的，但有学生和我讨论起 Muse vs. iPS cells 的关系。
好像2011年的 一篇 PNAS 文章（http://www.pnas.org/content/108/24/9875.long）发现 human fibroblasts 的 iPS cells 主要是（还是就只是？）从 Muse cells 来的。
那么 Muse vs iPS cells 的现状是什么？
是不是所有 iPS cells 都是从 Muse cells 来的？还是 Muse cells 是其中的一个主
要来源，但其他 cell types 也还是可以变成 iPS cells 的？
麻烦领域内的大妞小妞砖家们给个简单的总结？
谢谢了！ |
|
f**********r
发帖数: 18251 | 48 【 以下文字转载自 Joke 讨论区 】
发信人: biokold (kold), 信区: Joke
标 题: 转贴：《范博中Cell》， 苦逼千老写照 (转载)
发信站: BBS 未名空间站 (Tue Jun 24 00:35:12 2014, 美东)
发信人: dongHei200 (医学小子), 信区: Biology
标 题: 转贴：《范博中Cell》， 苦逼千老写照
发信站: BBS 未名空间站 (Mon Jun 23 13:33:06 2014, 美东)
范博做完实验回office，实验室刚来的rotation student、一块搬砖的千老俱各欢喜。
正待烧锅做饭，只见他老板Dr. 胡，手里拿着一盒miniprep柱和一瓶培养基，走了进来
。范博向他作揖，坐下。Dr. 胡道：“我自倒运，把个博后位置给与你这现世宝 ，历
年以来，不知累了我多少。如今不知因我积了甚么德，带挈你中了个PLoS ONE ，我所
以带个培养基来贺你。”范博唯唯连声，叫rotation student把柱和培养基收起来，在
实验台边上坐着。Rotation student自和小本科生在细胞间换m... 阅读全帖 |
|
U*******a
发帖数: 16 | 49 Senior Director, Commercial Cell Culture Development (req #31735)
Location: Framingham, Massachusetts
Department: Late Stage Process Development, Biologics Development/Science
The Senior Director of Commercial Cell Culture Development (CCCD) reports to
the Vice President of Late Stage Process Development (LSPD), Biologics
Development/Science, and is responsible for directing and managing various
activities related to cell culture development for Genzyme’s processes that
are in late stage devel... 阅读全帖 |
|
b**********g
发帖数: 141 | 50 【 以下文字转载自 Biology 讨论区 】
发信人: blueraindang (blueraindang), 信区: Biology
标 题: Stem cell scientist position available (San Diego)
发信站: BBS 未名空间站 (Thu Jun 30 01:57:00 2016, 美东)
Two positions are available at a San Diego based biotech company. The
candidate should have extensive hands-on experience in working with human
iPSC culture. Check here for more information http://www.ixcellsbiotech.com/Career. If you are interested, please send your CV/resume to [email protected]/* */
Company inform... 阅读全帖 |
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