g*********d 发帖数: 233 | 1 夏荣辉,李江
上海交通大学医学院,上海(200011)
E-mail:e******[email protected]
摘 要:基因的表观遗传学修饰正越来越受到人们的重视,它包括DNA甲基化和组蛋白修
饰,组蛋白修
饰又包括组蛋白乙酰化和组蛋白甲基化。基因的表观遗传学改变在基因转录调节方面有
重要作用。最
近研究较多的是多种组蛋白修饰方式和DNA甲基化在基因转录调节方面的共同作用,本
文详述组蛋白
修饰和DNA甲基化的发生机制,并且总结了组蛋白乙酰化和组蛋白甲基化与DNA甲基化之
间的相互作
用,提示不同位点的组蛋白甲基化与DNA甲基化共同作用于基因转录,并且发挥不同的
作用,具体体
现在组蛋白乙酰化、组蛋白H3K9、H3K27和H4K20甲基化与DNA甲基化协同作用,使基因
发生转录抑
制,而组蛋白H3K4甲基化与基因转录激活有关。
关键词:组蛋白修饰;DNA甲基化;关系
1. 引 言
目前,在研究肿瘤发生发展的过程中,基因的表观遗传学修饰所起的作用日益得到人们
的重视。组蛋
白修饰和DNA甲基化是两种最重要的表观遗传学修饰方式。研究表明,人类几乎所有类
型的肿瘤都存
在组蛋白及DNA甲基化的异常... 阅读全帖 |
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w*********i 发帖数: 1969 | 2 木木和白人果然同根同源,习俗都一样
一切赞颂全归真主!
作为穆斯林,我们被要求剃除阴毛。
为了清洁,属于圣行(模仿先知的行为)。先知穆罕默德认为属于人类赋性的有10
件大事,即剪髭须、割礼、用牙刷、呛鼻、剪指甲、洗趾节、拔腋毛、剃阴毛、节约用
水和漱口。
哈非兹(意思是“能背诵《古兰经》的人”)在圣训集的注释中说:
圣训说:al-‘aanah的意思是男人阴茎之上以及四周的毛发,于女人则指阴道四
周的毛发。据记载,它来自Abu’l-‘Abbaas ibn Surayj,那即是围绕直肠生长的毛发
。从这一切出发我们就可以理解,剃除前前后后以及遍及于那些地方的所有毛发是可嘉
的行为(穆斯泰哈卜)。说到剃,因为这是最常见的方法,不过拔毛或者是用热蜡脱毛
等等也是可以容许的。
Abu Shaamah说:al-‘aanah是长在rakab上的毛发,也就是说在凸起的腹部之下
和阴部之上。或者说它就是私处的最外部,就是阴部它自己,无论男女。前前后后剃除
阴毛的必须的,当然剃除后边的毛更重要,以免任何排泄物沾染到它,然后用水、石头
或者手纸等等清洁方式还不能去... 阅读全帖 |
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w********2 发帖数: 632 | 3 Experimental evidence
Many laboratory studies of bacterial conjugation, trans- duction and
transformation over the last 80 years have provided valuable insights into
some of the mechanisms and frequencies of HGT. More recently, field studies
on HGT support many of the laboratory findings (Souza et al., 2002) and
reveal the widespread occurrence of HGT amongst bacteria and viruses (Maeda
et al., 2006; Sander and Schmieger, 2001; van den Eede et al., 2004;
Weinbauer, 2004).
HGT has been recorded i... 阅读全帖 |
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l***j 发帖数: 3977 | 4 Ford has a device called a Purge Module. Basically what it does is to cycle
the blower motor on and off to dry out the evaporator and case so there is
no moisture to accelerate the growth of mold and mildew. It is part number
F8ZX-19980-AA and is available at any Ford, Lincoln or Mercury dealer. It
does require an adapter harness depending on the vehicle it is going in.
Ford这个number可能是F8XZ19980AA
General Motors has a similar system. It is called Electronic Evaporator
Dryer (EED). Where the Ford ... 阅读全帖 |
|
B*Z 发帖数: 7062 | 5 主要说的是中央差速器。这个是网上一个文章。附件是现在的subaru中央差速器分类。
There is a lot of confusion about the differences between the various Subaru
AWD systems:
? Continuous (for 5MT)
? Active (for 4EAT)
? VTD (for 5EAT)
? availability or non-availability of Rear LSD
So heres an attempt to explain the differences....
1. Continuous AWD System:
The manual transmission’s all-wheel drive is referred to as a continuous al
l-wheel drive system. It uses a center differential located inside the trans
mission... 阅读全帖 |
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C****i 发帖数: 1776 | 6 CHAPTER XVII
Of the Perseverance of the Saints
I. They, whom God hath accepted in his Beloved, effectually called, and sanc
tified by his Spirit, can neither totally nor finally fall away from the sta
te of grace, but shall certainly persevere therein to the end, and be eterna
lly saved.[334]
II. This perseverance of the saints depends not upon their own free will, bu
t upon the immutability of the decree of election, flowing from the free and
unchangeable love of God the Father;[335] upon the e... 阅读全帖 |
|
|
r*****g 发帖数: 7139 | 8 全球期货代码
代码 名称 交易所 合约大小
外汇期货板块,比如JPY,GBP,AUD,CAD,CHF
ZN 美国十年国债期货 CBOT 乘数1000(新增)成交占CBOT的大半
CL 轻甜原油 NYMEX 乘数1000
NG 天然气 NYMEX 乘数10000
COIL 布伦特原油 IPE 乘数1000
SI 白银 NYMEX 乘数5000
QI 小白银 NYMEX 乘数2500
QM 小原油 NYMEX 乘数500
HG 铜 NYMEX 乘数25000
GC 黄金 NYMEX 乘数100
ZS 黄豆 ECBOT 乘数5000
ZL 豆油 ECBOT 乘数60000
ZM 豆粕 ECBOT 乘数100
ZC 玉米 ECBOT 乘数5000
ZW 小麦 ECBOT 乘数5000
ZG 黄金 ECBOT 乘数100
YG 小黄金 ECBOT 乘数33.2
DD $25 大道指 ECBOT 每点$25
YM $5 小道指 ECBOT 每点$5
ZI 5000盎司白银ECBOT 乘数5000
K200 韩国指数 KSE 乘数50万
HSI 恒生指数 HKFE 乘数50
MHI 小恒指 HKFE... 阅读全帖 |
|
s********y 发帖数: 547 | 9 1、迈�7Fk3Mfg2on)
美国最有影响力的科技博客Techcrunch创始人Michael Arrington,他曾在硅谷科
技TechCrunch网站做编辑,他写的博客成为最有影响力的科技博客。
收入:每月50万美元至80万美元
出生:1970年3月13日,美国加利福尼亚
学历:斯坦福大学法学院(1995)、克莱蒙特麦肯纳学院(1992)、加州大学伯克
利分校。
2、皮特(Pete Cashmore)
Mashable是全球最大的社交媒体资讯网站之一。年仅19岁的凯什摩尔2005年在苏格
兰的家中自主创办了Mashable。据估计,该网站每月的页面浏览量为3000万以上,超过
了被AOL收购的TechCrunch。他也是全球十大科技博客创始人之一,涵盖了技术、业务
、社交媒体、娱乐、生活等。也是最具影响力的阅读数字与社交媒体,涵盖技术新闻等
。
收入:每月56万美元至60万美元。
出生:1985年9月18日,英国苏格兰。国籍美国。
教育:Banchory学院
3、马里奥·拉万德拉(Mario Lavanderia, ‘Perez Hilton’)化名:佩雷斯·
... 阅读全帖 |
|
o******r 发帖数: 259 | 10 http://news.xinhuanet.com/english2010/china/2011-07/24/c_131004
At least 33 dead, 190 injured in east China train crash
English.news.cn 2011-07-24 07:15:15 FeedbackPrintRSS
Rescue personnel work on the scene of the accident in Shuangyu Town in Wenzh
ou City of east China's Zhejiang Province, on July 24, 2011. Up to now 32 pe
ople were dead and 171 injured. D301 train from Beijing to Fuzhou rear-ended
the D3115 train at 8:50 p.m. The first four coaches of D301 and the 15th an
d 16th coaches o... 阅读全帖 |
|
n*******t 发帖数: 7254 | 11 http://www.fridae.asia/newsfeatures/2011/06/10/10935.if-only-ga
d-stop-feeling-guilty-for-being-different
Rev Dr Yap Kim Hao, a former Bishop of The Methodist Church in Singapore and
Malaysia who appears as himself in the recent Pink Dot promotional video, u
nderscores the importance of self-acceptance among LGBT people, and acceptin
g others in the community by embracing difference and celebrating diversity.
"If only gay people could stop feeling guilty for being different" is my tag
line in th... 阅读全帖 |
|
l****z 发帖数: 29846 | 12 Gilder sees a direct link from attitudes toward Israel, attitudes toward
Jewish excellence, and attitudes toward free enterprise itself.
By Ken Blackwell
November 25, 2011
In these days of Occupy Wall Street demonstrations across the U.S., it’s
important to see what motivates Obama administration policies here and
abroad. Mr. Obama, as a candidate, had to bat away accusations that he was
close, too close, to Rashid Khalidi, a radical Palestinian Arab intellectual
. Candidate Obama then sooth... 阅读全帖 |
|
o*******p 发帖数: 722 | 13 it eeds new door lock. $400+. Volvo sucks. |
|
c****r 发帖数: 3057 | 14 eed to be brand new, sealed.
bill pay only.
plz Email me at c********[email protected]
include :
your mitbbs id
item
price
quantity
zip code
Thanks |
|
s******b 发帖数: 967 | 15 eed new Canon MX892 printers to OH @ $118
Pls pm with your state-zip and email. |
|
m****s 发帖数: 18160 | 16 【 以下文字转载自 CivilEngineering 讨论区 】
发信人: EngEdu (James), 信区: CivilEngineering
标 题: 招"工程教育研究"博士研究生
关键字: 工程教育
发信站: BBS 未名空间站 (Thu Dec 26 18:06:48 2013, 美东)
PhD Graduate Research Assistantship Available
(Starting Summer or Fall 2014)
PhD in Engineering Education
Utah State University (Logan, Utah)
Background
Engineering Education, a new emerging discipline, grows rapidly in recent
years in parallel to traditional engineering disciplines such as mechanical,
civil, and electrical engineering. A PhD in... 阅读全帖 |
|
h********a 发帖数: 6364 | 17 是不是不同的人不一样啊
刚查新申请连接上是3000后
我的program记得好像是1500,忘记了,也许记错了
REWARDS: Earn cash rewards on all your purchases. Full terms and conditions
will be sent with your card. Up to 1% Cashback Bonus - Automatically earn 1%
unlimited Cashback Bonus on purchases after your total annual purchases exc
eed $3000; purchases that are part of your first $3000 earn .25%. Warehouse
purchases (those made at select warehouse clubs, discount stores and their a
ffiliates) earn .25%. |
|
h*****n 发帖数: 924 | 18 One really needs to think about whether s/he fits this profession if s/he n
eeds asking this question. |
|
c****r 发帖数: 3057 | 19 eed to be brand new, sealed.
bill pay only.
plz Email me at c********[email protected]
include :
your mitbbs id
item
price
quantity
zip code
Thanks |
|
s******b 发帖数: 967 | 20 eed new Canon MX892 printers to OH @ $118
Pls pm with your state-zip and email. |
|
f**********0 发帖数: 3128 | 21 我想要的物品:
spg biz refer
单张面值:
$70 match 合理价格
eed your first name and email address,
you will get 35000 pts through the referral
付款方式说明:
boa paypal or alipay
广告的有效期:
till gone |
|
v*****s 发帖数: 304 | 22 eed one to East
[1;32m我想要的物品:
[Label 求购]Canon MG6320 White Print[email protected]$80 East
单张面值:
Canon MG6320 White [email protected]$80
可接受的价格(必须明码标价!):
$65+my label
物品新旧要求:
New
邮寄方式要求:
fedex
买卖双方谁承担邮寄损失(Required if not code only):
default
付款方式说明:
paypal/billpay
其他补充说明:
广告的有效期:
物品来源:
我的联系方式:
bbs mail
二手交易风险自负!请自行验证是否合法和一手卡!: |
|
f*e 发帖数: 6992 | 23 http://www.consumeraffairs.com/news02/depot_gift.html
Home Depot
has agreed to stop treating gift cards like cash if they are lost or stolen.
Instead, in a settlement with the New York attorney general, Home Depot agr
eed to replace a lost or stolen card, assuming the customer has proof of pur
chase and valid identification.
可以打电话问问,又希望要回来。不过要快。估计如果被人用掉了就没戏了。 |
|
l***h 发帖数: 139 | 24 http://www.hometheaterhifi.com/volume_7_4/dvd-benchmark-proc
eed-pmdt-dvd-player-10-2000.html
I have a friend who is considering this player. He has a set
of $10k speakers and $5k 65" SONY XBR HDTV, so it might be
OK to burn another 5 grand on a DVD player. To me it's
ridiculous. I believe a $1.5K HTPC will do better and is a
lot more configurable/enjoyable -- imagine playing Quake III
with enemies in human size? |
|
m****s 发帖数: 18160 | 25 【 以下文字转载自 CivilEngineering 讨论区 】
发信人: EngEdu (James), 信区: CivilEngineering
标 题: 招"工程教育研究"博士研究生
关键字: 工程教育
发信站: BBS 未名空间站 (Thu Dec 26 18:06:48 2013, 美东)
PhD Graduate Research Assistantship Available
(Starting Summer or Fall 2014)
PhD in Engineering Education
Utah State University (Logan, Utah)
Background
Engineering Education, a new emerging discipline, grows rapidly in recent
years in parallel to traditional engineering disciplines such as mechanical,
civil, and electrical engineering. A PhD in... 阅读全帖 |
|
m****s 发帖数: 18160 | 26 【 以下文字转载自 ME 讨论区 】
发信人: EngEdu (James), 信区: ME
标 题: PhD positions in engineering education
发信站: BBS 未名空间站 (Fri Dec 27 16:11:51 2013, 美东)
Graduate Research Assistantships Available
(Starting in Summer or Fall 2014)
Utah State University
Background:
Engineering Education, a new and emerging discipline, has grown rapidly in
recent years, parallel to traditional engineering disciplines, such as
mechanical, electrical and civil engineering. The College of Engineering at
Utah State University (http:/... 阅读全帖 |
|
m****s 发帖数: 18160 | 27 【 以下文字转载自 Education 讨论区 】
发信人: EngEdu (James), 信区: Education
标 题: PhD in Engineering Education - Research Assistantships Available
发信站: BBS 未名空间站 (Sat Dec 28 13:39:35 2013, 美东)
Graduate Research Assistantships Available
(Starting in Summer or Fall 2014)
Utah State University
Background:
Engineering Education, a new and emerging discipline, has grown rapidly in
recent years, parallel to traditional engineering disciplines, such as
mechanical, electrical and civil engineering. The College of Engi... 阅读全帖 |
|
T*********e 发帖数: 9208 | 28 you are wasting energy efficiently. that's it.
for all you pools, lawns, those are luxury life that normal people doesn't n
eed, and can not be afforded by our earth.
Stop using them if you really want to do good to this environment.
that |
|
y****r 发帖数: 120 | 29 昨天晚上,两岁半的儿子美美的饱餐了一顿MACRONI CHEESE,之后又被妈妈带着出去看
洗车(他最喜欢的之一),回来后又吃了几个他最爱的李子干,最后发现自己失踪数日
的枕头竟然重新露面。那枕头其实是被妈妈藏起来了,因为他对那枕头简直发展到恋物
癖的地步,每天做什么事情都要带着,没办法只好骗他枕头坏了,等妈妈修好再给你。
昨天被阿姨给拆洗了,把里面的棉花重新整理又重新缝好,完璧归赵。经历了这一系列
的喜事,到了晚上洗澡之前他一直是情绪高涨,开心不已。
事情就在这时候突发的。我去给他放洗澡水,让他先在房间里跟自己久别重逢的枕头“
叙旧”。谁知等我放好了水再去房间叫他,却发现他的房间门怎么都拧不开了。他自己
也在里边不停的拧,试图打开。这时我的脑子里就“嗡”的一声响,顿时乱成了一团。
又试了几次,还是怎么都拧不开。此时儿子也有点着急了,我听见他说:“mommy, I n
eed help here." "open the door, open it!" |
|
M***6 发帖数: 410 | 30 No n eed to worry.
prevailing
h1b |
|
x********g 发帖数: 541 | 31 大家好:
有个问题想请教一下这里的各位,有知道的请说一声,先谢谢了。关于stem act中
有关授予学位的学校有规模的要求,还必须要求可以授予博士学位,而且要是注重研究
的大学。我想问一下这个要求是很模糊的还是很严格的。我弟弟在一所大学只有一个
EED教育学位是博士,其他的都是硕士学位。他如果在这样的学校读stem专业那以后会
被认可为stem act的受益者吗。虽然现在stem act还没下来,但我在给我弟弟选学校呢
。 |
|
l***g 发帖数: 221 | 32 你与其说你懒得和对方理论,不如承认不敢正视自己的软弱。很多中国人自我安慰不和
别人计较,懒得争论什么的,是个普遍现象。
当一个人向第三方说你弄丢了什么,你要第一时间制止,在第三人在场的情况下要求cl
arification。特别是向这种职位比你还低的,很简单的就是i feel offended and i n
eed to talk to your supervisor足够把对方镇住。
对方说你没有update system是工作里比较常见的扯皮,通常是发一份email下套让对方
先表明观点,然后再把证据亮出来反击,cc一堆人。对方出丑一两次以后就不敢了。
XX |
|
x********g 发帖数: 541 | 33 大家好:
有个问题想请教一下这里的各位,有知道的请说一声,先谢谢了。关于stem act中
有关授予学位的学校有规模的要求,还必须要求可以授予博士学位,而且要是注重研究
的大学。我想问一下这个要求是很模糊的还是很严格的。我弟弟在一所大学只有一个
EED教育学位是博士,其他的都是硕士学位。他如果在这样的学校读stem专业那以后会
被认可为stem act的受益者吗。虽然现在stem act还没下来,但我在给我弟弟选学校呢
。 |
|
x********g 发帖数: 541 | 34 大家好:
有个问题想请教一下这里的各位,有知道的请说一声,先谢谢了。关于stem act中
有关授予学位的学校有规模的要求,还必须要求可以授予博士学位,而且要是注重研究
的大学。我想问一下这个要求是很模糊的还是很严格的。我弟弟在一所大学只有一个
EED教育学位是博士,其他的都是硕士学位。他如果在这样的学校读stem专业那以后会
被认可为stem act的受益者吗。虽然现在stem act还没下来,但我在给我弟弟选学校呢
。 |
|
y**********9 发帖数: 566 | 35 5. Irfan Fazal, Saurabh Kumar, Poorya Saghari, Lou C. Christen,
Yunchu Li, Alan E. Willner, Martin M. Fejer, “SOA assisted data-
polarization-insensitive wavelength conversion in a PPLN waveguide by cross-
polarization-modulation of the pump using an SOA,” 2006 Optical Fiber
Communication Conference, and the 2006 National Fiber Optic Engineers
Conference, v 2006, Proceedings - Thirteenth International Symposium on
Temporal Representation and Reasoning, TIME 2006, p 1636718.
6. Yangjin... 阅读全帖 |
|
s******s 发帖数: 121 | 36 http://www.eetimes.com/electronics-news/4214667/Congress-hears-
H-1B-visas
Congress hears two views on H-1B visas
Rick Merritt
3/31/2011 3:16 PM EDT
SAN JOSE, Calif. – Congress got two prescriptions for the controversial H-1
B visa program in a public hearing Thursday (March 31).
The H-1B program has long been at the center of debate about immigration and
outsourcing policies in the U.S. The U.S. House of Representatives called
the hearing to come to grips with the conflicts between high tech e... 阅读全帖 |
|
x********g 发帖数: 541 | 37 大家好:
有个问题想请教一下这里的各位,有知道的请说一声,先谢谢了。关于stem act中
有关授予学位的学校有规模的要求,还必须要求可以授予博士学位,而且要是注重研究
的大学。我想问一下这个要求是很模糊的还是很严格的。我弟弟在一所大学只有一个
EED教育学位是博士,其他的都是硕士学位。他如果在这样的学校读stem专业那以后会
被认可为stem act的受益者吗。虽然现在stem act还没下来,但我在给我弟弟选学校呢
。 |
|
m*y 发帖数: 5861 | 38 各位大侠们帮我出出主意怎么才能少破点财。。。
上周四7点多下班回家,
照常黑灯瞎火上了高速101,
照常速度从最右边,第五条lane,逐步提速换到最左lane,
换lane过程中没有超过左边任何车,车速逐渐超过右边的车,
从上高速到换到最最后里面的lane的过程大概走了两个出口的距离,车速达到75-80mph
。
大概又走了不到一个出口,发现后面警灯亮了,被要求下出口在local路边pull over。
要求我出示驾照,保险,注册,一一照做,并且指着驾照后面贴的地址告诉他那不是我
的新地址,两个星期前刚搬了家。警察绕着我的车前后转了一圈,拿手电来回的照。然
后要求我眼睛看着他的手电,眼珠子跟着他的手电动,照做了。然后他就拿着我给的东
西回他车上去了。
大概五六分钟后回来让我签字。我发现他还是写着我的老地址,我跟他说地址错了,能
不能改,他说他不能改。我看了description,虽然他自己潦草,但是还是看清了“exc
eeding 65 mph”还有括号里面passed XXX unit没看清就问他这个什么意思,他说我超
过他了¥%……&*我就跟他说sorry。。。然后签字,然后他说我... 阅读全帖 |
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h**********r 发帖数: 174 | 39 how about this one?
How do we get married in New York City?
First you need to get a marriage license. You don't need an appointment (exc
ept for Staten Island where you need to make an appointment) and you don't n
eed a blood test.
Both the man and the woman must appear in person at one of the borough offic
es of the City Clerk of New York (sited in the Borough Halls in each borough
), bringing proof of identification (either original or certified copies of
passport, driver's license or non-driv |
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m******o 发帖数: 510 | 40 indeed, if you are not driving over 65mph, you can nearly always win your sp
eeding case. but this police is nice too.
to know why, check CA traffic law.
念头 |
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I*****y 发帖数: 6402 | 41 the health insurance offered to UCSD staff should be free TO YOU. You will n
eed to confirm this with your boss and HR.
refund |
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s*****A 发帖数: 478 | 42 出站为啥要刹车呢?
查了一下:
进站前要提前减速的,进站的速度一般是30-40公里/小时,i.e., 25mph, driving sp
eed in residential area
离家最近的地方,应该就是bart开始滑行进站的距离了,可能确实问题不太大
谢谢各位 |
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c********x 发帖数: 232 | 43 OK. Got you.
Haven't followed baseball closely these days. But I do get a sense that the
Jays underperform their talents. They actually have a very good team. They n
eed somebody like Jeter, seriously. |
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a**u 发帖数: 8107 | 44 50种算及格,实在太打击大家BSO的热情了,哈哈
还是按照目前版务组里最低水平的我的标准(20种)比较靠谱。
国内:小时候在公园里钓过鲫鱼,在稻田里摸过泥鳅(算手钓的好了)
美国:只掉过几个pond和小水库。
Sunfish:最开始的时候用蚯蚓在小pond里钓,几乎都是sunfish。后来用grub钓crappi
e,也常上各种各样的sunfish。本地的品种bluegill,redear,redbreast,pumpkin s
eed,green sunfish,rock bass等等都上过。
Crappie:钓crappie就是为了吃。black crappie上过无数,但是white crappie钓上来
的就不多,不过个头都很大。
Catfish:刚学钓鱼的时候很喜欢去钓catfish,按照刀神的办法吃fillet,剩下的做菜
地底肥。本地的三种blue catfish,bullhead catfish,channel catfish都上过。
LM bass。其实不太喜欢钓bass,主要是觉得不如crappie好吃。
white bass。 white bass赶上季节也是钓到... 阅读全帖 |
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m*********r 发帖数: 4692 | 45 Chiefs Agree To Terms With 13 Players
Chiefs President Carl Peterson announced on Monday that the club had agr
eed to terms with 13 Reserve/Future Free Agents.
The list of players who agreed to terms of two-year contracts include: S
Robb Butler, FB Greg Hanoian, DT Brian Howard, G Rob Hunt, QB Omar Jaco
bs, TE Adam Johnson, DE Montez Murphy, CB Zach Norton, CB Dimitri Patter
son, CB Justin Phinisee, LB Nick Reid, TE Keith Willis and LB Timi Wusu.
As per club policy, no further terms of the agree |
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ET 发帖数: 10701 | 46 it's not a good habit..
rule is rule. you can't play not by rule. you can creat your own rule, but
you n
eed understand what's the real rule.
even though you creat your own rule, your rule still needs to be fair so the
re won't be any argument later on. |
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v****e 发帖数: 19471 | 47 I don't see these top athletes screwing around and enjoying a few extra
holes as a problem at all, let alone a "mistake". all successful men enjoy a
few extra
pussies. needless to say these guys are younger and physically more attract
ive than most successful men, so they get even more tail. the social and leg
al environment makes it too easy for these bitches to blackmail them. that n
eeds to be changed. |
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k******6 发帖数: 952 | 48 觉得靠谱,打算实行一下,主题思想如下:
1. Consume high-quality protein at every meal.
2. Go ahead, eat fat 但要适量
3. Indulge in vegetables.
4. Avoid foods that contain sugar and starch
5. Limit your fruit and milk intake.
给了个每餐的参考:
Breakfast: Any type of eggs, whether scrambled, fried, boiled, poached, or m
ade into an omelet (with all the fixings). You can add cheese, of course, an
d serve with any type of meat - even bacon and sausage.
Snacks: Just about any type of cheese makes a great snack, as do nuts and s
ee... 阅读全帖 |
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b**j 发帖数: 20742 | 49 way more budget, 也way more expense啊。这个不是理由。but LHN broadcasting hi
gh school games does give an unfair advantage, honestly texas doesn't even n
eed this advantage to recruit texas kids, when's the last time texas lost
a top texas kid to another school? |
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